Abstract:
:Seventy-eight nondemented elderly depressed patients underwent an extensive battery of cognitive tests both before and after seven weeks of treatment with nortriptyline, phenelzine, or placebo. Clinical and cognitive evaluations of the patients were under double-blind conditions. Response to treatment did not appear to significantly affect cognitive capacity; neither did treatment with an active substance as compared to placebo. In addition, the baseline level of cognitive functioning did not appear related to whether a patient responded to treatment. The authors conclude that under optimal conditions neither antidepressant produces measurable changes in the cognitive capacity of nondemented elderly patients.
journal_name
Int Psychogeriatrjournal_title
International psychogeriatricsauthors
Georgotas A,McCue RE,Reisberg B,Ferris SH,Nagachandran N,Chang I,Mir Pdoi
10.1017/s1041610289000141subject
Has Abstractpub_date
1989-10-01 00:00:00pages
135-43issue
2eissn
1041-6102issn
1741-203Xjournal_volume
1pub_type
临床试验,杂志文章,随机对照试验abstract::ABSTRACTBackground:Cognitive decline is an important complication of joint replacement surgeries in senior people. METHODS:We determined incidence rates of dementia diagnosis following endoprosthetic joint replacement surgery (upper and lower extremities). The observation period covered up to 28 quarters using German...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217002976
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:Mild cognitive impairment (MCI) is proposed to describe the transitional stage between normal cognitive aging and dementia. It has had significant impact in the field of dementia research, but it remains controversial whether or not it should be used as a diagnostic category in clinical practice. METHODS:Se...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610208007126
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVES:To evaluate the impact of external memory devices on the efficacy of a package of internal mnemonic techniques. Participants wrote two types of lists during the study phase: (a) a list of study words and/or (b) a loci list. At recall, participants were not allowed to refer to either of the lists they had wri...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610203008755
更新日期:2003-03-01 00:00:00
abstract:BACKGROUND:Dementia caregiving has been linked to negative consequences for mental health in caregivers. Although depression seems to be an enduring psychological consequence associated with caregiving, little is known about the longitudinal effects that modulating variables related to coping strategies have on caregiv...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610211002237
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:The social and economic burden of Alzheimer's disease (AD) and its increasing prevalence has led to much work on new treatment strategies and clinical trials. The search for surrogate markers of disease progression continues but traditional parallel group trial designs that use well-established, but often in...
journal_title:International psychogeriatrics
pub_type: 杂志文章,评审
doi:10.1017/S1041610211001116
更新日期:2012-05-01 00:00:00
abstract::Neuroimaging has become part of the required investigations when assessing a patient with dementia. In this brief paper, we summarize the role of computed tomography (CT) in the routine work-up in dementia and provide some information about the role of the CT scan in the field of dementia research. Although CT is far ...
journal_title:International psychogeriatrics
pub_type: 杂志文章,评审
doi:10.1017/S1041610211000950
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Mental capacity has been little studied among older general hospital inpatients. METHODS:A retrospective analysis was undertaken of routinely collected data (age, gender, ethnicity, admission diagnosis, psychiatric diagnosis, Mini-mental State Examination score, whether capacity was assessed, the outcome of...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S104161020900917X
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:Concerns about suicide risk in people with dementia have been increasing in recent years along with a discourse about rational suicide and assisted suicide. METHODS:A systematic narrative literature review of suicidal behavior and assisted suicide in persons with dementia. RESULTS:Most studies that have ex...
journal_title:International psychogeriatrics
pub_type: 杂志文章,评审
doi:10.1017/S1041610215000629
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:It is of considerable public health importance to prevent or delay the progression of mild cognitive impairment (MCI) to more severely impaired cognitive states. This study examines the risk of progression from mild to severe cognitive impairment in relation to engagement in social activities while mildly im...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212002086
更新日期:2013-04-01 00:00:00
abstract::This article discusses the role of some pathogenetical factors in the main morphological variants of vascular dementia and their correlation with certain clinical parameters. On the basis of computer-tomographical (CT) studies of 62 patients with dementia, it was possible to distinguish three groups of patients, accor...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610292001054
更新日期:1992-10-01 00:00:00
abstract:BACKGROUND:The use of benzodiazepines is associated with increased risk of fall-related injuries in the elderly. However, it is unclear if the risks vary across the products and how they depend on the pattern of use and dosage. Specifically, the possibility of cumulative effects of past benzodiazepine use has not been ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610211002031
更新日期:2012-04-01 00:00:00
abstract::ABSTRACTBackground:The aim of this study is to identify the prevalence and risk factors of documented delirium in general practices in Germany. METHODS:The present study includes 2,194 patients over the age of 65 years with delirium and 2,194 controls without delirium from a sample of 6,180,042 patients from 1,262 ge...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217002587
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Subjective memory complaints (SMC) have been suggested as an early marker of mild cognitive impairment and dementia. However, there is a paucity of evidence on the effects of early life conditions on the development of SMC in old age. This study is aimed at investigating the association between childhood soc...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610219000814
更新日期:2019-12-01 00:00:00
abstract::ABSTRACTBackground:US suicide rates among older women have substantially increased over the past decade. We examined potential differences in sociodemographic and risk/precipitating factors among older female suicide decedents who died by drug overdose versus firearms, hanging/suffocation, and other means, and postmor...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610218000212
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVES:Geriatric depression complicates cognitive health in older adults. This study aims to investigate the impact of depressive symptoms on cognitive impairment in community-dwelling older adults, depending on whether cognitive dysfunction accompanied. DESIGN:A community-based longitudinal cohort study. SETTING...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610220003622
更新日期:2020-11-16 00:00:00
abstract:BACKGROUND:This study aimed to assess the prevalence, incidence, and persistence of suicidal ideation (SI), and to investigate the psychosocial factors associated with these. METHODS:A total of 1,204 community dwelling elderly adults aged 65 years or older were evaluated at baseline, 909 (75%) of whom were followed tw...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610213001634
更新日期:2014-01-01 00:00:00
abstract::The focus of this report is the treatment of persons with dementia who are of a non-English-speaking background (NESB). Noisemaking is one behavioral manifestation associated with severe dementia. It can have devastating effects on persons with dementia by limiting their access to activity programs and social interact...
journal_title:International psychogeriatrics
pub_type: 临床试验,杂志文章
doi:10.1017/s1041610299005864
更新日期:1999-09-01 00:00:00
abstract:BACKGROUND:Depressive symptoms are common in patients with Alzheimer's disease (AD) and increase the caregiver burden, although the etiology and pathologic mechanism of depressive symptoms in AD patients remain unclear. In this study, we tried to clarify the cerebral blood flow (CBF) correlates of subjective depressive...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610213002573
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Patient and carer participation in old age psychiatry is less developed than in other areas of mental health. What can we learn from the historical context about increasing participation and how can it be conceptualized? METHODS:The historical and policy context of patient and carer participation in the Nat...
journal_title:International psychogeriatrics
pub_type: 历史文章,杂志文章,评审
doi:10.1017/S1041610211001864
更新日期:2012-02-01 00:00:00
abstract::Most people who work in aged care have a fair idea of what is meant by cognitive impairment or decline, and we have some moderately robust instruments for detecting it and measuring change over time. Frailty is much more difficult to define, but like hard core pornography (Stewart, 1964), many of us "know it when we s...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217000060
更新日期:2017-04-01 00:00:00
abstract::Epidemiologic survey data were used to examine relationships between alcohol use and abuse and the physical and mental health status of elderly public housing residents (weighted n = 865) and to determine the influence that drinking behavior had on mortality. Residents with a current alcohol disorder (4%) were more li...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610298005407
更新日期:1998-09-01 00:00:00
abstract::Staging methodologies are an essential tool in the assessment of disease severity in progressive dementing illness. Several different instruments have been developed for this purpose. One of the most widely used methodologies is the Global Deterioration Scale/Functional Assessment Staging (GDS/FAST) system. This syste...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610297004869
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Hospital-treated deliberate self harm and suicide among older adults have rarely been examined at a national level. METHODS:The Irish Central Statistics Office provided suicide and undetermined death data for 1980-2006. The National Registry of Deliberate Self Harm collected data relating to deliberate self...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610210001377
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:In old age, both apathy and depression have been associated with an increased cardiovascular disease (CVD) risk. This study evaluated the mediating role of cardiovascular risk factors in the relationship of apathy and mood symptoms with incident CVD. METHODS:Prospective cohort study of 1,790 community-dwell...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610215001751
更新日期:2016-04-01 00:00:00
abstract::ABSTRACTBackground:The current research sought to characterize current mood state profiles in healthy young versus older adults using 100-point visual analogue mood scales (VAMS), provide within-sample and new sample replication of age-group differences, assess sex differences, and compare with commonly used standardi...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610218000996
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Elder mistreatment, social ageism, and human rights are increasingly powerful discourses in positioning older people in society, yet the relationship between them has rarely been subjected to critical investigation. This perceived relationship will have implications for how mistreatment is understood and res...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212002372
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:To examine the effects of complex cognitive (mahjong) and physical (Tai Chi) activities on dementia severity in nursing home residents with dementia. METHODS:Cluster-randomized open-label controlled design. 110 residents were randomized by nursing home into three conditions: mahjong, Tai Chi, and simple han...
journal_title:International psychogeriatrics
pub_type: 杂志文章,随机对照试验
doi:10.1017/S1041610213002524
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:Qualitative research has suggested that spousal carers of someone with dementia differ in terms of whether they perceive their relationship with that person as continuous with the premorbid relationship or as radically different, and that a perception of continuity may be associated with more person-centered...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212001743
更新日期:2013-02-01 00:00:00
abstract:BACKGROUND:Socioeconomic status (SES) has been identified as a possible risk factor for the development of dementia, with low SES shown to be associated with a higher prevalence of dementia, increased psychiatric comorbidity and worse baseline cognitive functioning. Few studies have actually looked at the impact of SES...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610209990846
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:The negative image of Alzheimer's disease (AD) in our society has a substantial impact on treating, caring for and integrating those suffering from the disease and their relatives. Little research has been conducted on social perception of AD in the community. METHODS:The aim of this study was to investigat...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610211001529
更新日期:2012-01-01 00:00:00