Abstract:
BACKGROUND:leishmaniasis infection might manifest as sarcoidosis; on the other hand, some evidences propose an association between sarcoidosis and leishmaniasis. Most of the times, it is impossible to discriminate idiopathic sarcoidosis from leishmaniasis by conventional histopathologic exam. AIM:We performed a cross-sectional study to examine the association of sarcoidosis with leishmaniasis in histopathologically diagnosed sarcoidal granuloma biopsy samples by polymerase chain reaction (PCR). MATERIALS AND METHODS:We examined paraffin-embedded skin biopsy samples obtained from patients with clinical and histopathological diagnosis as naked sarcoidal granuloma, referred to Skin Research Center of Shaheed Beheshti Medical University from January 2001 to March 2010, in order to isolate Leishmania parasite. The samples were reassessed by an independent dermatopathologist. DNA extracted from all specimens was analyzed by the commercially available PCR kits (DNPTM Kit, CinnaGen, Tehran, Iran) to detect endemic Leishmania species, namely leishmania major (L. major). RESULTS:L. major was positive in PCR of Eight out of twenty-five examined samples. CONCLUSION:Cutaneous leishmaniasis may be misinterpreted as sarcoidosis; in endemic areas, when conventional methods fail to detect Leishmania parasite, PCR should be utilized in any granulomatous skin disease compatible with sarcoidosis, regardless of the clinical presentation or histopathological interpretation.
journal_name
Indian J Dermatoljournal_title
Indian journal of dermatologyauthors
Moravvej H,Vesal P,Abolhasani E,Nahidi S,Mahboudi Fdoi
10.4103/0019-5154.131453subject
Has Abstractpub_date
2014-05-01 00:00:00pages
316issue
3eissn
0019-5154issn
1998-3611pii
IJD-59-316bjournal_volume
59pub_type
杂志文章abstract:Background:Leprosy is a chronic granulomatous infection primarily affecting the peripheral nervous system, skin and reticuloendothelial system. Cutaneous nerves are severely affected in lepra reaction and this leads to morbidity. Objective:To study electrophysiological pattern of different nerves involved in Type-II r...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/ijd.IJD_38_17
更新日期:2017-11-01 00:00:00
abstract::Dowling-Degos disease (DDD) is a late-onset genodermatosis characterized by hyperpigmented macules on the flexures along with scattered comedo-like lesions and pitted acneiform scars. Follicular Dowling-Degos is a rare type of DDD, with only two reports so far. It presents with follicular papules and comedo-like lesio...
journal_title:Indian journal of dermatology
pub_type:
doi:10.4103/ijd.IJD_260_18
更新日期:2020-07-01 00:00:00
abstract::Dermatofibromas are benign skin lesions that consist of pigmented papules or nodules. They produce the dimple sign when laterally squeezed and are usually found on the legs. These clinical features lead to the diagnosis in most cases. However, the differential diagnosis with other lesions, such as atypical nevi and me...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.110862
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:Oral isotretinoin treatment might influence the levels of vitamin B12 and folic acid. AIMS AND OBJECTIVES:The aim of this study is to compare vitamin B12 and folic acid levels in patients with moderate and severe acne vulgaris with those of the healthy control group and to investigate the effect of isotreti...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.143533
更新日期:2014-11-01 00:00:00
abstract::Patients on anti-TNFα therapy are at increased risk for rare opportunistic infections. Here we are reporting a case of Scedosporium apiospermum infection in a patient treated with anti-TNF for 5 years. Patients on anti-TNFα need close follow-up and clinicians should be suspicious for atypical infections in these immun...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.77560
更新日期:2011-01-01 00:00:00
abstract::A family presented to our dermatology clinic with a complaint of white nails. Physical examination revealed clinical feature of leukonychia totalis and the presence of sensorineural hearing loss, palmo plantar keratoderma and knuckle pads (four essential criteria for the diagnosis of Bart Pumphrey syndrome).Three cons...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.60365
更新日期:2010-01-01 00:00:00
abstract::Diffuse neurofibroma is an unusual variant of neurofibroma with the head and neck being the common sites of involvement. It is benign in nature and spreads superficially and has many ectatic blood vessels. Histologically it is similar to conventional neurofibromas except for a few peculiar distinguishing features. We ...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.169128
更新日期:2015-11-01 00:00:00
abstract::Klinefelter syndrome (KFS) is the most common non-heritable sex chromosome anomaly caused by nondisjunction during cell division and contains two or more X chromosomes. More than two third of all cases are homogenous (47XXY) and the remaining are mosaic (46XY/47XXY). Lower limb ulcers are frequently observed and attri...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.164373
更新日期:2015-09-01 00:00:00
abstract::A Case of faun-tail nevus is presented. A long tuft of hair over the back in the lumbar region hid a bony defect of the fifth lumbar spine. No neurological symptoms were encountered. ...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:
更新日期:1989-09-01 00:00:00
abstract::Two adult patients from a village of district Bhilwara, Rajasthan, consulted Skin Department of R. N. T. Medical College and Hospital, Udaipur, with complaints of thickening of the palms and soles and pigmentation of skin with a nonhealing ulcer on the palm. They also had complaints of loss of appetite, abdominal pain...
journal_title:Indian journal of dermatology
pub_type:
doi:10.4103/ijd.IJD_704_16
更新日期:2019-03-01 00:00:00
abstract:Context:Androgenic alopecia (AGA) is a hereditary androgen-dependent disorder, characterized by gradual conversion of terminal hair into miniaturized hair and defined by various patterns. Common age group affected is between 30 and 50 years. Metabolic syndrome (MetS) is a cluster of cardiovascular risk factors that inc...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/ijd.IJD_526_16
更新日期:2019-01-01 00:00:00
abstract::Eruptive syringoma is a very rare variant of syringoma. It is a benign adnexal tumor of the intraepidermal portion of eccrine sweat ducts. Here we report a 32-year-old female presented with classical asymptomatic eruptive syringomas involving her face and extremities. ...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.152586
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Acanthosis nigricans (AN) is a dermatosis characterized by thickened, hyperpigmented plaques, typically on the intertriginous surfaces and neck. Common in some populations, its prevalence depends on race. Clinicians should recognize AN; it heralds disorders ranging from endocrinologic disturbances to maligna...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.91828
更新日期:2011-11-01 00:00:00
abstract::Cancer of the oral cavity makes up approximately 30% of all head and neck region tumors. Skin metastasis is rare with an incidence ranging between 0.7% and 2.4%. Skin metastasis usually occurs in the neck, scalp, and over the skin near the primary site. We report a patient with carcinoma left buccal mucosa who present...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.185764
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Vitiligo is an acquired pigmentary disorder of the skin. Genetic factors, oxidative stress, autoimmunity, and neurochemical agents might be contributing factors for the development of the disease. AIMS:To evaluate the oxidative stress level and tyrosinase activity in vitiligo patients and to compare them wi...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.60344
更新日期:2010-01-01 00:00:00
abstract::As researchers, we often collect data on a clinical record form or a questionnaire. It is an important part of study design. If the questionnaire is not well designed, the data collected will not be useful. In this section of the module, we have discussed some practical aspects of designing a questionnaire. It is usef...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/ijd.IJD_76_17
更新日期:2017-03-01 00:00:00
abstract::A 48-year-old man presented with acute abdominal pain underwent laparotomy that revealed two perforated ulcers in jejunum. He had skin lesions with porcelain white atrophic scar which were ignored for 3 years, whereas the disease revealed own malignant nature and progressed to nervous, gastrointestinal, and cardiopulm...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.87157
更新日期:2011-09-01 00:00:00
abstract::Foot dermatitis refers to the predominant involvement of feet in the eczematous process. This study is undertaken to determine the clinical pattern and causative agent in foot eczema and to evaluate the role of patch testing in determining the causative agent of foot eczema. Data was collected from 50 patients with fo...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.41649
更新日期:2008-01-01 00:00:00
abstract::Crohn's disease (CD) is a type of inflammatory bowel disease that can affect any part of the gut from mouth to anus. It also may occur at contiguous sites, like, lip, perineal or peristomal regions or may occur at sites separated from the bowel by normal tissue referred to as metastatic CD. The condition is relatively...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/ijd.IJD_389_16
更新日期:2018-07-01 00:00:00
abstract::A 19 year old girl had mutilating palmoplantar keratoderma with generalised ichthyosiform dermatosis and linear verrucous plaques in popliteal fossae. Her mother had similar disorder. ...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:
更新日期:1989-03-01 00:00:00
abstract:AIM:To evaluate whether oxidative stress is implicated in melanocyte damage in vitiligo. BACKGROUND:Vitiligo is a complex disorder characterized by gradually enlarging areas of depigmentation. A new unifying hypothesis for the etiology of this pigment disorder is proposed, in which we postulate that the final destruct...
journal_title:Indian journal of dermatology
pub_type: 杂志文章,收录出版
doi:10.4103/0019-5154.55628
更新日期:2009-07-01 00:00:00
abstract:INTRODUCTION:Hand, foot, and mouth disease (HFMD), an enteroviral disease has emerged as a major emerging infection in India. This is caused most commonly by enterovirus 71 (EV71) and coxsackievirus A16 (CVA16) but can also be due to CVA4-10, CVA24, CVB2-5, and echovirus 18 (Echo18). Virological analysis of the cases o...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/ijd.IJD_381_17
更新日期:2017-09-01 00:00:00
abstract::An eccrine poroma is a solitary tumor arising from the eccrine duct epithelium in the epidermis. The lesions commonly occur on the sole of the foot, the hands, and occasionally on the nose, eyelids, neck, and chest. We report a patient who presented with a slow-growing nodular lesion over her left cheek, prompting a d...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.123515
更新日期:2014-01-01 00:00:00
abstract::Dermatitis neglecta is a condition that results from inadequate frictional cleansing leading to accumulation of corneocytes, sebum and sweat ultimately resulting in hyper-pigmented patch or verrucous plaque. Recognizing this condition avoids unnecessary, aggressive diagnostic and therapeutic procedures. Here we report...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.152525
更新日期:2015-03-01 00:00:00
abstract::Pemphigus is a chronic, potentially life threatening, autoimmune intraepidermal blistering disease affecting the skin and the mucous membrane. Pemphigus may have profound impact on the quality of life in the affected patients. Counselling and adjuvant psychotherapy may be beneficial at least in few patients and should...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/ijd.IJD_198_17
更新日期:2017-05-01 00:00:00
abstract::Venereology-the study of venereal diseases or more recently, the sexually transmitted infections (STI) includes a variety of pathogens namely viruses, bacteria, fungi and protozoa for which the common factor is the mode of transmission and acquisition: Sexual relations between human beings. Medical and other historian...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.84713
更新日期:2011-07-01 00:00:00
abstract::Melanoma is a rare form of cutaneous malignancy encountered in the dark skin population. Epidermotropic metastatic melanoma is a rare form of cutaneous metastatic melanoma which can mimic primary melanoma on histopathology. Hence its differentiation is of immense prognostic importance. The occurrence of rim of depigme...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.117323
更新日期:2013-09-01 00:00:00
abstract:Introduction:Mycobacterium leprae has a small genome and a tendency of persisting as a very low-grade infection. The authors have shown earlier, that the changes in TTC repeats, in M. leprae genome may contribute to the restriction of the pathogenicity of the bacterium and its survival strategy in case of pure neural H...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/ijd.IJD_90_18
更新日期:2018-11-01 00:00:00
abstract::Palmo-plantar keratodermas (PPKD) are a diverse group of acquired and hereditary disorders, characterized by excessive thickening of the skin of palms and soles. Here, we report a case of Type I or Buschke-Fischer-Brauer variant of punctate palmo-plantar keratoderma, in a 66-year-old gentleman. The association of our ...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.156452
更新日期:2015-05-01 00:00:00
abstract:UNLABELLED:Vitiligo is a common skin disorder, and the pathogenesis is unknown. An increased prevalence of autoimmune thyroid diseases has been described in these patients. The aim of this study is to assess the prevalence of thyroid dysfunction and hypoparathyroidism in patients with vitiligo. MATERIALS AND METHODS:O...
journal_title:Indian journal of dermatology
pub_type: 杂志文章
doi:10.4103/0019-5154.39733
更新日期:2008-01-01 00:00:00