Somatomedin-binding proteins: what role do they play in the growth process?

abstract：:Five patients, 11 months to 3 4/12 years old with severe normochromic, normocytis anemia and reticulocytopenia are reported. At the height of erythropoietic arrest when erythroid precursor cells were completely absent, undifferentiated stem cells (transitional cells), accumulated in the bone marrow. They disappeared a...

journal_title：European journal of pediatrics

authors： Tillmann W,Prindull G,Schröter W

更新日期：1976-08-16 00:00:00

abstract：:Since the first description by Catel and Manzke of hyperphalangy and clinodactyly of the index finger associated with Robin malformation sequence, seven further cases have been published. In two families more than one case occurred. Another family is presented with possibly two affected boys showing variable features ...

journal_title：European journal of pediatrics

authors： Brude E

更新日期：1984-08-01 00:00:00

abstract：:Factor VIII procoagulant activity and factor VIII related antigen were examined in 20 full-term and preterm newborn infants during the first days of life. The control group involved 15 adults volunteers. Factor VIII activity was estimated by a one-stage test and factor VIII related antigen was determined by immunelect...

journal_title：European journal of pediatrics

authors： Maak B,Scheidt B,Frenzel J

更新日期：1978-07-19 00:00:00

abstract：UNLABELLED:The aim of this study is to give a systematic overview on publications having investigated the allergy preventive effect of extensively and/or partially hydrolysed infant formulas. Publications were searched by several strategies. Inclusion criteria were: prospective cohort study, randomisation, family histo...

journal_title：European journal of pediatrics

authors： Schoetzau A,Gehring U,Wichmann HE

更新日期：2001-06-01 00:00:00

abstract：:The glycogen storage disorders (GSD)-I, -III, -VI and -VIII are associated with hypertriglyceridaemia or mixed hyperlipidaemia which poses the question whether these patients have an increased risk for atherosclerosis. The atherogenicity of triglycerides has remained controversial, while increased plasma cholesterol l...

journal_title：European journal of pediatrics

authors： Schmitz G,Hohage H,Ullrich K

更新日期：1993-01-01 00:00:00

abstract：UNLABELLED:Severe head injuries in children (under 15 years of age) have many features that differentiate them from head injuries in adults. In such cases, non-surgical treatment cannot always prevent fatal herniation. We report on seven cases of children with severe head injury, presenting with decorticate posturing a...

journal_title：European journal of pediatrics

authors： Hejazi N,Witzmann A,Fae P

更新日期：2002-02-01 00:00:00

abstract：:The effects of laryngoscopy and tracheal intubation on cerebral and systemic haemodynamics were studied in 30 children. The objective was to identify conditions in which the alterations of cerebral and systemic haemodynamics were minimal. The children were intubated after muscular relaxation and following 10 min of me...

journal_title：European journal of pediatrics

authors： Bode H,Ummenhofer W,Frei F

更新日期：1993-11-01 00:00:00

abstract：:Early identification of infants being at high risk to become obese at their later childhood or adolescence can be of vital importance in any obesity prevention initiative. The aim of the present study was to examine the utility and applicability of the "Childhood Obesity Risk Evaluation (CORE)" index as a screening to...

journal_title：European journal of pediatrics

authors： Manios Y,Vlachopapadopoulou E,Moschonis G,Karachaliou F,Psaltopoulou T,Koutsouki D,Bogdanis G,Carayanni V,Hatzakis A,Michalacos S

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Human immunodeficiency virus type 1 (HIV-1) infected children treated with highly active antiretroviral therapy (HAART) may develop a significant reduction of plasma viremia associated with an increase in CD4+ T-cell counts. Functional capacity of this reconstituted immune system in response to recall antige...

journal_title：European journal of pediatrics

authors： Ching N,Deville JG,Nielsen KA,Ank B,Wei LS,Sim MS,Wolinsky SM,Bryson YJ

更新日期：2007-01-01 00:00:00

abstract：UNLABELLED:This study compared the foot morphology of Spanish schoolchildren based on their body mass index and age and analyzed whether body mass index affects the child's foot development at primary school. Cross-sectional study of 1,032 schoolchildren (497 boys and 535 girls), 6-12 years old. Height and weight were ...

journal_title：European journal of pediatrics

authors： Jiménez-Ormeño E,Aguado X,Delgado-Abellán L,Mecerreyes L,Alegre LM

更新日期：2013-05-01 00:00:00

abstract：:Female patients with congenital adrenal hyperplasia have been frequently studied in order to determine the impact of prenatal androgen exposure on various aspects of psychological, psychosocial and psychosexual development. There is no published study to evaluate the impact of the genital malformation, genital operati...

journal_title：European journal of pediatrics

authors： Kuhnle U,Bullinger M,Schwarz HP

更新日期：1995-09-01 00:00:00

abstract：:To determine the relationship between total serum bilirubin (TSB) during the first 2 days of life and subsequent neonatal morbidity in very low birth weight (VLBW, less than 1500 g) infants. We performed a prospective study of 582 VLBW infants born between July 1, 2005 and December 31, 2009. TSB was measured in umbili...

journal_title：European journal of pediatrics

authors： Zhu J,Xu Y,Zhang G,Bao Y,Wu M,Du L

更新日期：2012-04-01 00:00:00

abstract：:Positional plagiocephaly (PP) denotes flattening of the skull that occurs frequently in healthy infants. Aim of this study was to estimate the prevalence of positional plagiocephaly and to identify the risk factors in a cohort of healthy infants in order to help prevention of PP. In a prospective design, all healthy f...

journal_title：European journal of pediatrics

authors： Ballardini E,Sisti M,Basaglia N,Benedetto M,Baldan A,Borgna-Pignatti C,Garani G

更新日期：2018-10-01 00:00:00

abstract：:Congenital adrenal hyperplasia (CAH) is an inherited metabolic disease caused by the deficiency of one of the enzymes necessary for cortisol synthesis. With carefully supervised medical treatment, CAH patients have the capacity for normal puberty and fertility. We report on a 12.4-year-old female who, because of the e...

journal_title：European journal of pediatrics

authors： Tahirovic H,Toromanovic A,Grubic M,Grubic Z,Dumic K

更新日期：2009-07-01 00:00:00

abstract：UNLABELLED:In patients with propionic acidaemia (PA), the increased intracellular concentration of propionyl-CoA leads to a relative abundance of odd-numbered long-chain fatty acids (OLCFAs) in body lipids. We investigated the relative amount of OLCFA in erythrocyte membrane lipids over a period of 1-8 years in five pa...

journal_title：European journal of pediatrics

authors： Sperl W,Murr C,Skladal D,Sass JO,Suormala T,Baumgartner R,Wendel U

更新日期：2000-01-01 00:00:00

abstract：:Adolescents have specific healthcare needs distinct from adults or younger children secondary to anatomical, physiological and socio-behavioural differences. Healthcare providers have been slow to address this, leading the UK Department of Health (2011) to publish 'You're Welcome' quality criteria for services for you...

journal_title：European journal of pediatrics

authors： Tuckwell R,Wood D,Mansfield-Sturgess S,Brierley J

更新日期：2017-02-01 00:00:00

abstract：:Child maltreatment is a major social problem with many adverse consequences, and a substantial number of maltreated children are not identified by health care professionals. In 2010, in order to improve the identification of maltreated children in hospitals, a new hospital-based policy was developed in Amsterdam, The ...

journal_title：European journal of pediatrics

authors： Hoytema van Konijnenburg EM,Sieswerda-Hoogendoorn T,Brilleslijper-Kater SN,van der Lee JH,Teeuw AH

更新日期：2013-02-01 00:00:00

abstract：UNLABELLED:Fibronectin (a glycoprotein which modulates inflammation) may decrease mortality in systemic infection. Children with meningococcal disease (MCD) may have low fibronectin levels. We aimed to compare plasma fibronectin levels in children with MCD and controls, correlate fibronectin levels with interleukin-6 (...

journal_title：European journal of pediatrics

authors： Riordan FA,Bestwick K,Thomson AP,Sills JA,Hart CA

更新日期：1997-06-01 00:00:00

abstract：:The traditional recommendation that Swiss children receive vitamin D during the first year of life was recently extended to the second and third year of life and during winter for older children. The aim of the study was to identify how Swiss pediatricians prescribe vitamin D. Between December 2016 and March 2017, 795...

journal_title：European journal of pediatrics

authors： Santi M,Janner M,Simonetti GD,Lava SAG

更新日期：2019-07-01 00:00:00

abstract：:There are three forms of high frequency ventilation, high frequency jet ventilation (HFJV, up to 400/min), high frequency oscillation (HFO, up to 40 Hz), and high frequency positive pressure ventilation (HFPPV, rates between 60 and 150/min). The first two forms of ventilation are still experimental and have been used ...

journal_title：European journal of pediatrics

authors： Greenough A,Milner AD

更新日期：1987-09-01 00:00:00

abstract：UNLABELLED:To examine the value of surfactant protein D and KL-6 as markers for the diagnosis and the severity of interstitial pneumonia caused by measles infection, surfactant protein D, KL-6 and lactic acid dehydrogenase were measured serially in three patients with measles complicated by interstitial pneumonia as co...

journal_title：European journal of pediatrics

authors： Arai Y,Obinata K,Sato Y,Hisata K,Tadokoro R,Tawa T,Kinoshita K

更新日期：2001-07-01 00:00:00

abstract：:The light- and electron-microscopic structure of articular and costal cartilage in a case of achondrogenesis type I has been described. The most characteristic ultrastructural change in the chondrocytes was conspicuous dilatation of the rough endoplasmatic reticulum (RER) which contained amorphous electronopaque mater...

journal_title：European journal of pediatrics

authors： Molz G,Spycher MA

更新日期：1980-06-01 00:00:00

abstract：UNLABELLED:Cleidocranial dysplasia (CCD; MIM 119600) is an autosomal dominant skeletal dysplasia characterised by hypoplastic clavicles, patent fontanelles, short stature, tooth anomalies and other variable skeletal changes. Different mutations of the RUNX2/CBFA1 gene (MIM 600211) have been detected in patients with CC...

journal_title：European journal of pediatrics

authors： Morava E,Kárteszi J,Weisenbach J,Caliebe A,Mundlos S,Méhes K

更新日期：2002-11-01 00:00:00

abstract：:Vitamin D is important for calcium homeostasis, muscle, and bone health. It has also immunomodulatory capacities in vivo and in vitro. Regulatory T cells (Treg) have been found to suppress a number of T cell-mediated immune disorders, including allergic responses and autoimmune diseases. This study aimed to investigat...

journal_title：European journal of pediatrics

authors： Güven A,Ecevit A,Sözer O,Tarcan A,Tarcan A,Ozbek N

更新日期：2012-08-01 00:00:00

abstract：:Thrombocypenic purpura was noted in a 3-year-old Japanese girl with an active varicella infection. The administration of intravenous gamma globulin (IVG) drastically improved bleeding manifestations as well as the active varicella infection. We believe that IVG should be the first choice of therapy for thrombocytopeni...

journal_title：European journal of pediatrics

authors： Hara T,Mizuno Y,Igarashi H,Ueda K

更新日期：1987-09-01 00:00:00

abstract：:An Arab Moslem kindred is reported in which six abnormal male fetuses were born in three closely related sibships. They had amelia, malformed head and other severe skeletal and visceral malformations. The similarities and differences between the developmental and inherent characteristics found in our patients and in f...

journal_title：European journal of pediatrics

authors： Zimmer EZ,Taub E,Sova Y,Divon MY,Pery M,Peretz BA

更新日期：1985-11-01 00:00:00

abstract：:We aimed to describe the experiences of children and adolescents with congenital heart disease (CHD). Electronic databases were searched until August 2016. Qualitative studies of children's perspectives on CHD were included. Data was extracted using thematic synthesis. From 44 studies from 12 countries involving 995 c...

journal_title：European journal of pediatrics

authors： Chong LSH,Fitzgerald DA,Craig JC,Manera KE,Hanson CS,Celermajer D,Ayer J,Kasparian NA,Tong A

更新日期：2018-03-01 00:00:00

abstract：:Male pseudohermaphroditism (MPH) is defined as incomplete masculinization in patients with normal male karyotype (XY) and testicular histology. MPH encompasses a spectrum of female to male phenotypes and presents both diagnostic and technical challenges to the surgeon. Once gender is assigned, based on phenotype, adeq...

journal_title：European journal of pediatrics

authors： Packer MG

更新日期：1993-01-01 00:00:00

abstract：:Protein C deficiency can lead to cerebrovascular occlusive disease. We describe a patient in whom heterozygous protein C deficiency (type 1) is suspected on the grounds of reduced protein C activity and who suffered from multiple thrombo-embolic events involving the brain and peripheral organs. The patient developed h...

journal_title：European journal of pediatrics

authors： Schmitt S,Auberger K,Fendel T,Kiess W

更新日期：1992-06-01 00:00:00

abstract：:Arterial hypertension in childhood is less frequent as compared to adulthood but is more likely to be secondary to an underlying disorder. After ruling out more obvious causes, some patients still present with strongly suspected secondary hypertension of yet unknown etiology. A number of these children have hypertensi...

journal_title：European journal of pediatrics

authors： Simonetti GD,Mohaupt MG,Bianchetti MG

更新日期：2012-10-01 00:00:00