Abstract：
:We explore here the possibility that polypeptide chains with directional multiplicity might provide for the control of peptide self-assembly processes. We tested this new possibility using an oppositely directed peptide (ODP) supramolecular system. The ODP could make it possible to form a βαβ motif with antiparallel β-sheets, which does not exist in nature. Furthermore, the designed ODPs were able to self-assemble into discrete, homogeneous, and structured protein-like controlled nano-objects. ODPs represent a simple but powerful unnatural self-assembling peptide system that can become a basic scaffold for fabricating more complex and elaborate artificial nanostructures.
journal_name
Biomacromoleculesjournal_title
Biomacromoleculesauthors
Jeong WJ,Han S,Park H,Jin KS,Lim YBdoi
10.1021/bm500313fsubject
Has Abstractpub_date
2014-06-09 00:00:00pages
2138-45issue
6eissn
1525-7797issn
1526-4602journal_volume
15pub_type
杂志文章abstract：:Although micelles are commonly used for drug delivery purposes, their long-term fate is often unknown due to photobleaching of the fluorescent labels or the use of toxic materials. Here, we present a metal-free, nontoxic, nonbleaching, fluorescent micelle that can address these shortcomings. A simple, yet versatile, p...
journal_title：Biomacromolecules
pub_type： 杂志文章
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journal_title：Biomacromolecules
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journal_title：Biomacromolecules
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journal_title：Biomacromolecules
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journal_title：Biomacromolecules
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更新日期：2007-02-01 00:00:00
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journal_title：Biomacromolecules
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更新日期：2011-06-13 00:00:00
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journal_title：Biomacromolecules
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journal_title：Biomacromolecules
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更新日期：2009-11-09 00:00:00
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