Preparation of biopolymer fibers by electrospinning from room temperature ionic liquids.

Abstract:

:Electrospinning is a versatile process used to prepare micro- and nano- sized fibers from various polymers dissolved in volatile solvents. In this report, cellulose and cellulose-heparin composite fibers are prepared from nonvolatile room temperature ionic liquid (RTIL) solvents by electrospinning. RTILs are extracted from the biopolymer fiber after the fiber formation using a cosolvent. Micron to nanometer sized, branched fibers were obtained from 10% (w/w) concentration of polysaccharide biopolymer in RTIL solution with an applied voltage of 15-20 kV. Cellulose-heparin composite fibers showed anticoagulant activity, demonstrating that the bioactivity of heparin remained unaffected even on exposure to a high voltage involved in electrospinning.

journal_name

Biomacromolecules

journal_title

Biomacromolecules

authors

Viswanathan G,Murugesan S,Pushparaj V,Nalamasu O,Ajayan PM,Linhardt RJ

doi

10.1021/bm050837s

keywords:

subject

Has Abstract

pub_date

2006-02-01 00:00:00

pages

415-8

issue

2

eissn

1525-7797

issn

1526-4602

journal_volume

7

pub_type

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