Efficacy of periodontal plastic surgery procedures in the treatment of localized facial gingival recessions. A systematic review.


BACKGROUND:The aim of this Systematic Review (SR) was to assess the clinical efficacy of periodontal plastic surgery procedures in the treatment of localized gingival recessions (Rec) with or without inter-dental clinical attachment loss (iCAL). MATERIAL AND METHODS:Electronic and hand searches were performed to identify randomized clinical trials (RCTs) on treatment of single gingival recessions with at least 6 months of follow-up. Primary outcome variable was complete root coverage (CRC). Secondary outcome variables were recession reduction (RecRed) and keratinized tissue (KT) gain. To evaluate treatment effect, Odds Ratios were combined for dichotomous data and mean differences in continuous data using a random-effect model. RESULTS:Fifty-one RCTs (53 articles) with a total of 1574 treated patients (1744 recessions) were included in this SR. Finally, 30 groups of comparisons were identified and a total of 80 meta-analyses were performed. Coronally Advanced Flap (CAF) was associated with higher probability of CRC and higher amount of RecRed than Semilunar Coronal Positioned Flap (SCPF). The combination CAF plus Connective Tissue Graft (CAF+CTG) or CAF plus Enamel Matrix Derivative (CAF+EMD) was more effective than CAF alone in terms of CRC and RecRed. The combination CAF plus Collagen Matrix (CAF+CM) achieved higher RecRed than CAF alone. In addition, CAF+CTG achieved CRC more frequently than CAF+EMD, SCPF, Free Gingival Graft (FGG) and Laterally Positioned Flap (LPS). CAF+CTG was also associated with higher RecRed than Barrier Membranes (CAF+GTR), CAF+EMD and CAF+CM. GTR was not able to improve the clinical efficacy of CAF. Studies adding Acellular Dermal Matrix (ADM) under CAF showed a large heterogeneity and not significant benefits compared with CAF alone. Multiple combinations, using more than a single graft/biomaterial under the flap, usually provide similar or less benefits than simpler, control procedures in term of root coverage outcomes. CONCLUSIONS:CAF procedures alone or with CTG, EMD are supported by large evidence in modern periodontal plastic surgery. CAF+CTG achieved the best clinical outcomes in single gingival recessions with or without iCAL.


J Clin Periodontol


Cairo F,Nieri M,Pagliaro U




Has Abstract


2014-04-01 00:00:00








41 Suppl 15


  • Depth of alveolar bone dehiscences in relation to gingival recessions.

    abstract::Dehiscence depths were measured in vivo during surgical treatment of 113 teeth with gingival recession in 27 subjects. The average dehiscence depth determined was 5.43 mm with an average recession depth of 2.67 mm. Statistical evidence of a correlation between recession depth and dehiscence depth (average distance bet...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章


    authors: Löst C

    更新日期:1984-10-01 00:00:00

  • Membranes over the lateral window in sinus augmentation procedures: a two-arm and split-mouth randomized clinical trials.

    abstract:OBJECTIVE:This study evaluates whether or not, among other factors, membrane-coverage of antrostomy defects improves implant survival in sinus augmentation procedures. MATERIALS AND METHODS:We performed a two-arm and split-mouth randomized controlled clinical trial on 104 and 5 patients respectively. In the two-arm st...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,随机对照试验


    authors: García-Denche JT,Wu X,Martinez PP,Eimar H,Ikbal DJ,Hernández G,López-Cabarcos E,Fernandez-Tresguerres I,Tamimi F

    更新日期:2013-11-01 00:00:00

  • A study to assess the plaque inhibitory action of a new zinc citrate toothpaste formulation.

    abstract:BACKGROUND, AIMS:Zinc-citrate-containing toothpastes have previously been suggested to be of value at inhibiting plaque and gingival inflammation. Present formulations have included triclosan which is thought to contribute major antibacterial/antiplaque effects. Alternative antimicrobial agents and other ingredients su...

    journal_title:Journal of clinical periodontology

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Moran J,Addy M,Corry D,Newcombe RG,Haywood J

    更新日期:2001-02-01 00:00:00

  • Generation of inflammatory stimuli: how bacteria set up inflammatory responses in the gingiva.

    abstract:OBJECTIVES:The primary aetiologic factor of periodontal disease is the bacterial biofilm. Gram-positive and gram-negative bacteria possess a plethora of structural or secreted components that may cause direct destruction to periodontal tissues or stimulate host cells to activate a wide range of inflammatory responses. ...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,评审


    authors: Madianos PN,Bobetsis YA,Kinane DF

    更新日期:2005-01-01 00:00:00

  • A biomechanical assessment of the relation between the oral implant stability at insertion and subjective bone quality assessment.

    abstract:AIM:The study was set to evaluate the validity of subjective jaw bone quality assessment. MATERIALS AND METHODS:A total of 298 patients (198 females, mean age 56.4) were treated with oral implants at the Periodontology Department at the University Hospital of KUL. A total of 761 TiUnite implants have been installed. S...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章


    authors: Alsaadi G,Quirynen M,Michiels K,Jacobs R,van Steenberghe D

    更新日期:2007-04-01 00:00:00

  • Microbiology of destructive periodontal disease in adolescent patients with congenital neutropenia. A report of 3 cases.

    abstract:BACKGROUND, AIMS:Congenital neutropenia is one condition that may predispose for destructive periodontal disease at a young age. In this report, we describe the microbiology of 3 adolescent patients with congenital neutropenia two of whom suffered from severe periodontitis. METHOD:Microbiological testing of the parent...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章


    authors: van Winkelhoff AJ,Schouten-van Meeteren AY,Baart JA,Vandenbroucke-Grauls CM

    更新日期:2000-11-01 00:00:00

  • Clinical research activity in periodontal medicine: a systematic mapping of trial registers.

    abstract:AIM:The primary aim of the study was to systematically map registration records on periodontal medicine in clinical trial registers. The secondary aim was to assess the evolution of periodontal medicine in clinical periodontal research as a whole. MATERIAL AND METHODS:We searched all registration records related to pe...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,评审


    authors: Monsarrat P,Blaizot A,Kémoun P,Ravaud P,Nabet C,Sixou M,Vergnes JN

    更新日期:2016-05-01 00:00:00

  • Comparison of circulating tumour necrosis factor superfamily cytokines in periodontitis patients undergoing supportive therapy: a case-controlled cross-sectional study comparing smokers and non-smokers in health and disease.

    abstract:BACKGROUND:B-cells are prominent immune cells in established periodontitis lesions. Tumour necrosis factor superfamily (TNFSF) cytokines play roles in supporting B-cell function as well as bone re-modelling. The influence of smoking on factors that support B-cell function in periodontitis remains unclear. AIM:To inves...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章


    authors: Nile CJ,Sherrabeh S,Ramage G,Lappin DF

    更新日期:2013-09-01 00:00:00

  • Incorporating antibiotics into platelet-rich fibrin: A novel antibiotics slow-release biological device.

    abstract:BACKGROUND:The aim of the present in vitro study was to explore the possibility of using platelet-rich fibrin (PRF) as a local sustained released device for antibiotics. MATERIALS AND METHODS:Platelet-rich fibrin was prepared with the addition of antibiotics (5 mg/ml metronidazole; 150 mg/ml clindamycin; 1 mU/ml penic...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章


    authors: Polak D,Clemer-Shamai N,Shapira L

    更新日期:2019-02-01 00:00:00

  • Peri-implant reconstruction using autologous periosteum-derived cells and guided bone regeneration.

    abstract:AIM:This investigation evaluated the bone healing in peri-implant defects treated with periosteum-derived cells (PCs) and guided bone regeneration (GBR). MATERIAL AND METHODS:PCs were harvested from six beagle dogs and characterized in vitro with regard to their osteogenic properties. The animals were subjected to tee...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章


    authors: Ribeiro FV,Suaid FF,Ruiz KG,Rodrigues TL,Carvalho MD,Nociti FH,Sallum EA,Casati MZ

    更新日期:2010-12-01 00:00:00

  • Probiotic effects of orally administered Lactobacillus reuteri-containing tablets on the subgingival and salivary microbiota in patients with gingivitis. A randomized clinical trial.

    abstract:OBJECTIVE:To investigate the effects of an orally administered probiotic on the oral microbiota. METHODS:A placebo-controlled, parallel study was conducted in 40 gingivitis subjects during 8 weeks. Treatment consisted on the administration of a daily tablet, either containing Lactobacillus reuteri or placebo. Unstimul...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,随机对照试验


    authors: Iniesta M,Herrera D,Montero E,Zurbriggen M,Matos AR,Marín MJ,Sánchez-Beltrán MC,Llama-Palacio A,Sanz M

    更新日期:2012-08-01 00:00:00

  • Association between periodontal condition and the development of type 2 diabetes mellitus-Results from a 15-year follow-up study.

    abstract:AIM:To study whether periodontal condition is associated with the development of type 2 diabetes mellitus (T2DM). MATERIALS AND METHODS:A population-based follow-up study was conducted among persons born in 1935 and living in the city of Oulu, Finland (n = 395). The baseline examinations were done during 1990-1992, an...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章


    authors: Myllymäki V,Saxlin T,Knuuttila M,Rajala U,Keinänen-Kiukaanniemi S,Anttila S,Ylöstalo P

    更新日期:2018-11-01 00:00:00

  • Periodontal treatment of rapid progressive periodontitis in 2 siblings with Papillon-Lefèvre syndrome: 15-year follow-up.

    abstract:AIMS:This paper reports the treatment of the periodontal component of the Papillon-Lefèvre syndrome in 2 siblings (case A, born 1974; case B, born 1976). METHOD:The initial treatment, in 1982, consisted of extraction of all primary teeth, scaling and rootplaning of the erupted permanent teeth and systemic antibiotic t...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章


    authors: De Vree H,Steenackers K,De Boever JA

    更新日期:2000-05-01 00:00:00

  • Local delivery of chemotherapeutic agents in periodontal therapy: has its time arrived?

    abstract::The concept of locally delivering chemotherapeutic agents to the periodontal pocket as a method to treat periodontal disease has been studied for over 20 years. A number of locally delivered chemotherapeutic agents in periodontal therapy are either currently available or under investigation. Clinical efficacy derives ...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章


    authors: Finkelman RD,Williams RC

    更新日期:1998-11-01 00:00:00

  • Clinical effects of root instrumentation using conventional steel or non-tooth substance removing plastic curettes during supportive periodontal therapy (SPT).

    abstract::Although root instrumentation has been accepted as the most important cause-related treatment of periodontal diseases, repeated scaling and root planing may over time result in substantive loss of tooth substance and increased sensitivity of the teeth. In an effort to minimize these side effects of therapy, non-root s...

    journal_title:Journal of clinical periodontology

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Bardet P,Suvan J,Lang NP

    更新日期:1999-11-01 00:00:00

  • The relationship of the periodontal status to fluoride levels of alveolar bone and tooth roots.

    abstract::The periodontal status and fluoride levels of alveolar bone and tooth roots were compared for subjects from a high (2.5 ppm F) and a low (less than 0.05 ppm F) fluoride area. The plaque index, gingival index, probing depth and loss of attachment were measured to determine the periodontal status. The fluoride levels we...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章


    authors: Reddy J,Grobler SR

    更新日期:1988-04-01 00:00:00

  • Clinical, microbiological and host defense parameters associated with a case of localized prepubertal periodontitis.

    abstract::A 4-year-old Japanese boy was referred to Osaka University Dental Hospital because of severe mobility and pain of the right lower primary canine. The canine had severe bone loss and a pocket depth exceeding 5-6 mm. The left lower canine showed slight mobility and moderate alveolar bone loss. The other primary teeth sh...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章


    authors: Yoshida-Minami I,Kishimoto K,Suzuki A,Fujiwara T,Shintani S,Morisaki I,Sobue S,Miyamoto M,Nagai A,Kurihara H

    更新日期:1995-01-01 00:00:00

  • Entire papilla preservation technique in the regenerative treatment of deep intrabony defects: 1-Year results.

    abstract:AIM:This study evaluates the clinical outcomes of a novel tunnel-like surgical technique in the treatment of isolated deep intrabony defects. MATERIAL AND METHODS:Twelve patients presenting with at least one isolated deep intrabony defect received regenerative periodontal treatment with "entire papilla preservation (E...

    journal_title:Journal of clinical periodontology



    authors: Aslan S,Buduneli N,Cortellini P

    更新日期:2017-09-01 00:00:00

  • Human intrabony defect regeneration with micrografts containing dental pulp stem cells: A randomized controlled clinical trial.

    abstract:AIM:The goal of this study was to evaluate if dental pulp stem cells (DPSCs) delivered into intrabony defects in a collagen scaffold would enhance the clinical and radiographic parameters of periodontal regeneration. MATERIALS AND METHODS:In this randomized controlled trial, 29 chronic periodontitis patients presentin...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,随机对照试验


    authors: Ferrarotti F,Romano F,Gamba MN,Quirico A,Giraudi M,Audagna M,Aimetti M

    更新日期:2018-07-01 00:00:00

  • Oral hygiene phase revisited: How different study designs have affected results in intervention studies.

    abstract::Every periodontal researcher have been taught, and every textbook in periodontics have advocated, that a phase in which the patient is meticulously motivated and instructed in proper oral hygiene-the oral hygiene phase-must be included in any periodontal intervention. However, how is this oral hygiene phase actually p...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,评审


    authors: Preus HR,Maharajasingam N,Rosic J,Baelum V

    更新日期:2019-05-01 00:00:00

  • Post-extraction dimensional changes: A systematic review and meta-analysis.

    abstract:AIM:To analyse the evidence pertaining to post-extraction dimensional changes in the alveolar ridge after unassisted socket healing. MATERIALS AND METHODS:The protocol of this PRISMA-compliant systematic review (SRs) was registered in PROSPERO (CRD42020178857). A literature search to identify studies that fulfilled th...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章,评审


    authors: Couso-Queiruga E,Stuhr S,Tattan M,Chambrone L,Avila-Ortiz G

    更新日期:2021-01-01 00:00:00

  • Prevalence of self-reported gingival bleeding in a representative sample of the Brazilian adolescent population.

    abstract:AIM:To estimate the prevalence of self-reported gingival bleeding in a representative sample of 12- to 17-year-old Brazilian adolescents. MATERIALS AND METHODS:Sociodemographic and oral health information were obtained through a self-administered questionnaire of the Study of Cardiovascular Risk Factors in Adolescents...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章


    authors: Nadanovsky P,Dos Santos APP,Bloch KV

    更新日期:2018-08-01 00:00:00

  • The effects of a simplified mechanical oral hygiene regime plus supragingival irrigation with chlorhexidine or metronidazole on subgingival plaque.

    abstract::23 patients with pockets greater than or equal to 4 mm and evidence of bone loss on radiographs received thorough scaling and root planing followed by instruction in Bass brushing. They refrained from routine interdental cleaning for the first 28 days. A pulsating jet irrigator was used once daily supragingivally with...

    journal_title:Journal of clinical periodontology

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Sanders PC,Linden GJ,Newman HN

    更新日期:1986-03-01 00:00:00

  • Self-reported questionnaire for surveillance of periodontitis in Chinese patients from a prosthodontic clinic: a validation study.

    abstract:BACKGROUND AND PURPOSE:Periodontal maintenance is critical for the long-term success of prosthodontic treatment. This study investigates the validity of questionnaires/models in monitoring periodontitis for Chinese prosthodontic patients. METHODS:In total, 114 patients completed the questionnaire. The chi-squared test...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章


    authors: Wu X,Weng H,Lin X

    更新日期:2013-06-01 00:00:00

  • Comparative longitudinal study of 2 methods of scheduling maintenance visits: 4-year data.

    abstract::116 subjects were recruited from a population of patients previously treated for adult periodontitis and maintained in periodontal health by means of periodic prophylaxes every 3-6 months. The subjects were divided into a control (C) and a test (T) group. A total of 33 patients in the T group and 47 in the C group com...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章


    authors: Listgarten MA,Sullivan P,George C,Nitkin L,Rosenberg ES,Chilton NW,Kramer AA

    更新日期:1989-02-01 00:00:00

  • Chemiluminescent assay of alkaline phosphatase in human gingival crevicular fluid: investigations with an experimental gingivitis model and studies on the source of the enzyme within crevicular fluid.

    abstract::The purpose of this study was to investigate how levels of gingival crevicular fluid (GCF) alkaline phosphatase (ALP) change in relation to levels of plaque and gingival inflammation in 20 adults during a 21 day period of experimental gingivitis. The source of ALP within GCF was also investigated using a repeat sampli...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章


    authors: Chapple IL,Socransky SS,Dibart S,Glenwright HD,Matthews JB

    更新日期:1996-06-01 00:00:00

  • The effect of electronic dental analgesia during sonic scaling.

    abstract::The aim of the present study was to investigate the effects of electronic dental analgesia (EDA) during sonic scaling. The clinical trial included 30 healthy adult subjects and was conducted as a randomised single-blind split-mouth design. The applied procedure consisted of periodontal scaling by means of a sonic scal...

    journal_title:Journal of clinical periodontology

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Jacobs R,van Steenberghe D

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  • Essential oil mouthwashes: a key component in oral health management.

    abstract::This Supplement provides clear evidence that essential oil (EO) mouthwashes can be a beneficial, safe component of daily oral health routines. However, despite the wealth of supporting evidence, several issues are worthy of discussion. Patient compliance is a clear issue with oral home-care routines, and the emphasis ...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章


    authors: Claffey N

    更新日期:2003-01-01 00:00:00

  • Flow-cytometric analysis of lymphocyte subsets in patients with advanced periodontitis.

    abstract::Peripheral blood lymphocytes from 36 patients with advanced periodontitis and from 34 healthy subjects were examined using a panel of monoclonal antibodies and fluorescence flow cytometry. The absolute and relative counts of B-cells, T-cells, T-helper (TH), T-suppressor/cytotoxic (TS) cells, activated T-cells and natu...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章


    authors: Zafiropoulos GG,Flores-de-Jacoby L,Schoop B,Havemann K,Heymanns J

    更新日期:1990-10-01 00:00:00

  • The association between missing teeth and non-alcoholic fatty liver disease in adults.

    abstract:AIMS:Long-term oral chronic inflammatory process is closely related to systemic inflammation, which is a main mechanism involved in non-alcoholic fatty liver disease (NAFLD). Tooth loss could reflect the accumulation of oral local inflammation, implying that number of missing teeth may associate with NAFLD. This study ...

    journal_title:Journal of clinical periodontology

    pub_type: 杂志文章


    authors: Qiao F,Fu K,Zhang Q,Liu L,Meng G,Wu H,Xia Y,Bao X,Gu Y,Shi H,Sun S,Wang X,Zhou M,Jia Q,Song K,Niu K

    更新日期:2018-08-01 00:00:00