The transcriptional co-activator multiprotein bridging factor 1 from the fungal insect pathogen, Beauveria bassiana, mediates regulation of hyphal morphogenesis, stress tolerance and virulence.

Abstract:

:Multiprotein bridging factors (MBFs) are evolutionarily highly conserved cofactors that link TATA-binding protein and the associated basal transcription machinery to transcription factors. The filamentous fungus, Beauveria bassiana, has a multipotential lifestyle capable of growing as a saprophyte, plant endophyte and insect pathogen. Deletion of the single B. bassiana MBF homologue (BbMBF1) affected fungal growth and hyphal morphogenesis, stress response and virulence. Compared with wild type, the ΔBbMBF1 strain displayed increased sensitivity to UV-irradiation and to oxidative, osmotic and heat stress, and decreased virulence in both topical and intrahaemocoel injection bioassays using the greater wax moth, Galleria mellonella larvae. Although only minor radial growth effects were seen for the ΔBbMBF1 strain, aberrant hyphal morphogenesis was observed, which could be rescued by growth in rich broth media. Transcriptional analysis during stress response showed altered gene expression in ΔBbMBF1 during growth under osmotic, oxidative and thermal stress conditions. Genome-wide expression analyses during growth under unstressed and thermal stress conditions revealed global gene expression changes and a set of putative targets for MBF1 mediated gene expression control. Our data indicate that BbMBF1 acts as a key regulatory cofactor controlling stress responses and virulence and that MBF1 dependent and independent pathways control proper hyphal morphogenesis.

journal_name

Environ Microbiol

authors

Ying SH,Ji XP,Wang XX,Feng MG,Keyhani NO

doi

10.1111/1462-2920.12450

subject

Has Abstract

pub_date

2014-06-01 00:00:00

pages

1879-97

issue

6

eissn

1462-2912

issn

1462-2920

journal_volume

16

pub_type

杂志文章
  • Elements of the heterocyst-specific transcriptome unravelled by co-expression analysis in Nostoc sp. PCC 7120.

    abstract::Nitrogen is frequently limiting microbial growth in the environment. As a response, many filamentous cyanobacteria differentiate heterocysts, cells devoted to N2 fixation. Heterocyst differentiation is under the control of the master regulator HetR. Through the characterization of the HetR-dependent transcriptome in N...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/1462-2920.14647

    authors: Brenes-Álvarez M,Mitschke J,Olmedo-Verd E,Georg J,Hess WR,Vioque A,Muro-Pastor AM

    更新日期:2019-07-01 00:00:00

  • Development and application of the human intestinal tract chip, a phylogenetic microarray: analysis of universally conserved phylotypes in the abundant microbiota of young and elderly adults.

    abstract::In this paper we present the in silico assessment of the diversity of variable regions of the small subunit ribosomal RNA (SSU rRNA) gene based on an ecosystem-specific curated database, describe a probe design procedure based on two hypervariable regions with minimal redundancy and test the potential of such probe de...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/j.1462-2920.2009.01900.x

    authors: Rajilić-Stojanović M,Heilig HG,Molenaar D,Kajander K,Surakka A,Smidt H,de Vos WM

    更新日期:2009-07-01 00:00:00

  • Transcriptional profiling of Gram-positive Arthrobacter in the phyllosphere: induction of pollutant degradation genes by natural plant phenolic compounds.

    abstract::Arthrobacter chlorophenolicus A6 is a Gram-positive, 4-chlorophenol-degrading soil bacterium that was recently shown to be an effective colonizer of plant leaf surfaces. The genetic basis for this phyllosphere competency is unknown. In this paper, we describe the genome-wide expression profile of A.chlorophenolicus on...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/1462-2920.12375

    authors: Scheublin TR,Deusch S,Moreno-Forero SK,Müller JA,van der Meer JR,Leveau JH

    更新日期:2014-07-01 00:00:00

  • Microbial manganese(III) reduction fuelled by anaerobic acetate oxidation.

    abstract::Soluble manganese in the intermediate +III oxidation state (Mn3+ ) is a newly identified oxidant in anoxic environments, whereas acetate is a naturally abundant substrate that fuels microbial activity. Microbial populations coupling anaerobic acetate oxidation to Mn3+ reduction, however, have yet to be identified. We ...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/1462-2920.13829

    authors: Szeinbaum N,Lin H,Brandes JA,Taillefert M,Glass JB,DiChristina TJ

    更新日期:2017-09-01 00:00:00

  • The faulty SOS response of Pseudomonas putida KT2440 stems from an inefficient RecA-LexA interplay.

    abstract::Despite its environmental robustness Pseudomonas putida strain KT2440 is very sensitive to DNA damage and displays poor homologous recombination efficiencies. To gain an insight into this deficiency isogenic ∆recA and ∆lexA1 derivatives of prophage-free strain P. putida EM173 were generated and responses of the recA a...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/1462-2920.15384

    authors: Akkaya Ö,Aparicio T,Pérez-Pantoja D,de Lorenzo V

    更新日期:2021-01-03 00:00:00

  • Prevalence and antibiotic resistance pattern of Salmonella serovars in integrated crop-livestock farms and their products sold in local markets.

    abstract::Major concern in the Mixed Crop-Livestock (MCL) farms, in which livestock and vegetables grown closely in the same facility, is cross-contamination of zoonotic bacterial pathogens especially Salmonella. To investigate the distribution of Salmonella serovars in MCL and their products, a total of 1287 pre-harvest sample...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/1462-2920.13265

    authors: Peng M,Salaheen S,Almario JA,Tesfaye B,Buchanan R,Biswas D

    更新日期:2016-05-01 00:00:00

  • Design and validation of 16S rRNA probes to enumerate members of the Clostridium leptum subgroup in human faecal microbiota.

    abstract::Among human faecal bacteria, many members of the Clostridium leptum subgroup are fibrolytic and butyrate producing microorganisms thereby contributing to processes important to colonic health. Yet this phylogenetic subgroup remains poorly described to date. To improve detection and description of members of the C. lep...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/j.1462-2920.2005.00763.x

    authors: Lay C,Sutren M,Rochet V,Saunier K,Doré J,Rigottier-Gois L

    更新日期:2005-07-01 00:00:00

  • Elucidation of sevadicin, a novel non-ribosomal peptide secondary metabolite produced by the honey bee pathogenic bacterium Paenibacillus larvae.

    abstract::American foulbrood (AFB) caused by the bee pathogenic bacterium Paenibacillus larvae is the most devastating bacterial disease of honey bees worldwide. From AFB-dead larvae, pure cultures of P. larvae can normally be cultivated indicating that P. larvae is able to defend its niche against all other bacteria present. R...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/1462-2920.12417

    authors: Garcia-Gonzalez E,Müller S,Ensle P,Süssmuth RD,Genersch E

    更新日期:2014-05-01 00:00:00

  • Identification of a calcium-controlled negative regulatory system affecting Vibrio cholerae biofilm formation.

    abstract::Vibrio cholerae's capacity to cause outbreaks of cholera is linked to its survival and adaptability to changes in aquatic environments. One of the environmental conditions that can vary in V. cholerae's natural aquatic habitats is calcium (Ca(+2)). In this study, we investigated the response of V. cholerae to changes ...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/j.1462-2920.2009.01923.x

    authors: Bilecen K,Yildiz FH

    更新日期:2009-08-01 00:00:00

  • Pyomelanin-producing Pseudomonas aeruginosa selected during chronic infections have a large chromosomal deletion which confers resistance to pyocins.

    abstract::When bacterial lineages make the transition from free-living to permanent association with hosts, they can undergo massive gene losses, for which the selective forces within host tissues are unknown. We identified here melanogenic clinical isolates of Pseudomonas aeruginosa with large chromosomal deletions (66 to 270 ...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/1462-2920.13336

    authors: Hocquet D,Petitjean M,Rohmer L,Valot B,Kulasekara HD,Bedel E,Bertrand X,Plésiat P,Köhler T,Pantel A,Jacobs MA,Hoffman LR,Miller SI

    更新日期:2016-10-01 00:00:00

  • Communal metabolism by Methylococcaceae and Methylophilaceae is driving rapid aerobic methane oxidation in sediments of a shallow seep near Elba, Italy.

    abstract::The release of abiotic methane from marine seeps into the atmosphere is a major source of this potent greenhouse gas. Methanotrophic microorganisms in methane seeps use methane as carbon and energy source, thus significantly mitigating global methane emissions. Here, we investigated microbial methane oxidation at the ...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/1462-2920.14728

    authors: Taubert M,Grob C,Crombie A,Howat AM,Burns OJ,Weber M,Lott C,Kaster AK,Vollmers J,Jehmlich N,von Bergen M,Chen Y,Murrell JC

    更新日期:2019-10-01 00:00:00

  • Escherichia coli has multiple enzymes that attack TNT and release nitrogen for growth.

    abstract::There has been a growing interest in the degradation of 2,4,6-trinitrotoluene (TNT) over the last decade, ever since its removal from polluted sites was declared an international environmental priority. Certain aerobic and anaerobic microorganisms are capable of using TNT as an N source, although very few studies have...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/j.1462-2920.2007.01272.x

    authors: González-Pérez MM,van Dillewijn P,Wittich RM,Ramos JL

    更新日期:2007-06-01 00:00:00

  • Targeting spatiotemporal dynamics of planktonic SAGMGC-1 and segregation of ammonia-oxidizing thaumarchaeota ecotypes by newly designed primers and quantitative polymerase chain reaction.

    abstract::The annual dynamics of three different ammonia-oxidizing archaea (AOA) ecotypes (amoA gene) and of the SAGMGC-1 (Nitrosotalea-like aquatic Thaumarchaeota) group (16S rRNA gene) were studied by newly designed specific primers and quantitative polymerase chain reaction analysis in a deep oligotrophic high mountain lake ...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/1462-2920.12191

    authors: Restrepo-Ortiz CX,Auguet JC,Casamayor EO

    更新日期:2014-03-01 00:00:00

  • Isolation and molecular detection of methylotrophic bacteria occurring in the human mouth.

    abstract::Diverse methylotrophic bacteria were isolated from the tongue, and supra- and subgingival plaque in the mouths of volunteers and patients with periodontitis. One-carbon compounds such as dimethylsulfide in the mouth are likely to be used as growth substrates for these organisms. Methylotrophic strains of Bacillus, Bre...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/j.1462-2920.2005.00805.x

    authors: Anesti V,McDonald IR,Ramaswamy M,Wade WG,Kelly DP,Wood AP

    更新日期:2005-08-01 00:00:00

  • Insights into the antibiotic resistance dissemination in a wastewater effluent microbiome: bacteria, viruses and vesicles matter.

    abstract::Wastewater treatment plants effluents are considered as hotspots for the dispersion of antibiotic resistance genes (ARGs) into natural ecosystems. The bacterial resistome (ARG collection in a metagenome) analyses have provided clues on antibacterial resistance dynamics. However, viruses and vesicles are frequently ign...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/1462-2920.14758

    authors: Maestre-Carballa L,Lluesma Gomez M,Angla Navarro A,Garcia-Heredia I,Martinez-Hernandez F,Martinez-Garcia M

    更新日期:2019-12-01 00:00:00

  • Formation of granules and Methanosaeta fibres in an anaerobic migrating blanket reactor (AMBR).

    abstract::It has generally been accepted that the formation of granules in anaerobic wastewater treatment systems requires a hydraulic upflow pattern. To evaluate this hypothesis, we operated an anaerobic migrating blanket reactor (AMBR) without a hydraulic upflow pattern, using a synthetic wastewater containing acetate, propio...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/j.1462-2920.2004.00597.x

    authors: Angenent LT,Sung S,Raskin L

    更新日期:2004-04-01 00:00:00

  • The influence of soil pH on the diversity, abundance and transcriptional activity of ammonia oxidizing archaea and bacteria.

    abstract::Autotrophic ammonia oxidation occurs in acid soils, even though laboratory cultures of isolated ammonia oxidizing bacteria fail to grow below neutral pH. To investigate whether archaea possessing ammonia monooxygenase genes were responsible for autotrophic nitrification in acid soils, the community structure and phylo...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/j.1462-2920.2008.01701.x

    authors: Nicol GW,Leininger S,Schleper C,Prosser JI

    更新日期:2008-11-01 00:00:00

  • Quinolone-resistant Escherichia coli isolated from birds of prey in Portugal are genetically distinct from those isolated from water environments and gulls in Portugal, Spain and Sweden.

    abstract::The influence of geographic distribution and type of habitat on the molecular epidemiology of ciprofloxacin resistant Escherichia coli was investigated. Ciprofloxacin resistant E. coli from wastewater, urban water with faecal contamination and faeces of gulls, pigeons and birds of prey, from Portugal, Spain and Sweden...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/1462-2920.12231

    authors: Vredenburg J,Varela AR,Hasan B,Bertilsson S,Olsen B,Narciso-da-Rocha C,Bonnedahl J,Stedt J,Da Costa PM,Manaia CM

    更新日期:2014-04-01 00:00:00

  • Conversion of cis-2-carboxycyclohexylacetyl-CoA in the downstream pathway of anaerobic naphthalene degradation.

    abstract::The cyclohexane derivative cis-2-(carboxymethyl)cyclohexane-1-carboxylic acid [(1R,2R)-/(1S,2S)-2-(carboxymethyl)cyclohexane-1-carboxylic acid] has previously been identified as metabolite in the pathway of anaerobic degradation of naphthalene by sulfate-reducing bacteria. We tested the corresponding CoA esters of iso...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/1462-2920.13806

    authors: Weyrauch P,Zaytsev AV,Stephan S,Kocks L,Schmitz OJ,Golding BT,Meckenstock RU

    更新日期:2017-07-01 00:00:00

  • Large-scale distribution and activity patterns of an extremely low-light-adapted population of green sulfur bacteria in the Black Sea.

    abstract::The Black Sea chemocline represents the largest extant habitat of anoxygenic phototrophic bacteria and harbours a monospecific population of Chlorobium phylotype BS-1. High-sensitivity measurements of underwater irradiance and sulfide revealed that the optical properties of the overlying water column were similar acro...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/j.1462-2920.2010.02178.x

    authors: Marschall E,Jogler M,Hessge U,Overmann J

    更新日期:2010-05-01 00:00:00

  • Double-tagged fluorescent bacterial bioreporter for the study of polycyclic aromatic hydrocarbon diffusion and bioavailability.

    abstract::Bacterial degradation of polycyclic aromatic hydrocarbons (PAHs), ubiquitous contaminants from oil and coal, is typically limited by poor accessibility of the contaminant to the bacteria. In order to measure PAH availability in complex systems, we designed a number of diffusion-based assays with a double-tagged bacter...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/j.1462-2920.2009.01952.x

    authors: Tecon R,Binggeli O,van der Meer JR

    更新日期:2009-09-01 00:00:00

  • Specificity in the settlement -- modifying response of bacterial biofilms towards zoospores of the marine alga Enteromorpha.

    abstract::Previous studies have shown that the rate of settlement of zoospores of the green alga Enteromorpha is stimulated by mixed microbial biofilms and that the number of zoospores settling is positively correlated with the number of bacteria in the biofilm. In the present study the specificity of this relationship has been...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1046/j.1462-2920.2003.00407.x

    authors: Patel P,Callow ME,Joint I,Callow JA

    更新日期:2003-05-01 00:00:00

  • Diversity of human colonic butyrate-producing bacteria revealed by analysis of the butyryl-CoA:acetate CoA-transferase gene.

    abstract::Butyrate-producing bacteria play an important role in the human colon, supplying energy to the gut epithelium and regulating host cell responses. In order to explore the diversity and culturability of this functional group, we designed degenerate primers to amplify butyryl-CoA:acetate CoA-transferase sequences from fa...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/j.1462-2920.2009.02066.x

    authors: Louis P,Young P,Holtrop G,Flint HJ

    更新日期:2010-02-01 00:00:00

  • Replication, lies and lesser-known truths regarding experimental design in environmental microbiology.

    abstract::A recent analysis revealed that most environmental microbiologists neglect replication in their science (Prosser, 2010). Of all peer-reviewed papers published during 2009 in the field's leading journals, slightly more than 70% lacked replication when it came to analyzing microbial community data. The paucity of replic...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/j.1462-2920.2011.02445.x

    authors: Lennon JT

    更新日期:2011-06-01 00:00:00

  • Distribution of S-layers on the surface of Bacillus cereus strains: phylogenetic origin and ecological pressure.

    abstract::Bacillus anthracis, Bacillus cereus and Bacillus thuringiensis have been described as members of the Bacillus cereus group but are, in fact, one species. B. anthracis is a mammal pathogen, B. thuringiensis an entomopathogen and B. cereus a ubiquitous soil bacterium and an occasional human pathogen. In two clinical iso...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1046/j.1462-2920.2001.00220.x

    authors: Mignot T,Denis B,Couture-Tosi E,Kolstø AB,Mock M,Fouet A

    更新日期:2001-08-01 00:00:00

  • Variation at the common polysaccharide antigen locus drives lipopolysaccharide diversity within the Pseudomonas syringae species complex.

    abstract::The common polysaccharide antigen (CPA) of the lipopolysaccharide (LPS) from Pseudomonas syringae is highly variable, but the genetic basis for this is poorly understood. We have characterized the CPA locus from P. syringae pv. actinidiae (Psa). This locus has genes for l- and d-rhamnose biosynthesis and an operon cod...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/1462-2920.15250

    authors: Jayaraman J,Jones WT,Harvey D,Hemara LM,McCann HC,Yoon M,Warring SL,Fineran PC,Mesarich CH,Templeton MD

    更新日期:2020-12-01 00:00:00

  • A dynamic microbial sulfur cycle in a serpentinizing continental ophiolite.

    abstract::Serpentinization is the hydration and oxidation of ultramafic rock, which occurs as oceanic lithosphere is emplaced onto continental margins (ophiolites), and along the seafloor as faulting exposes this mantle-derived material to circulating hydrothermal fluids. This process leads to distinctive fluid chemistries as m...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/1462-2920.15006

    authors: Sabuda MC,Brazelton WJ,Putman LI,McCollom TM,Hoehler TM,Kubo MDY,Cardace D,Schrenk MO

    更新日期:2020-06-01 00:00:00

  • Transcriptional characterization of Vibrio fischeri during colonization of juvenile Euprymna scolopes.

    abstract::The marine bacterium Vibrio fischeri is the monospecific symbiont of the Hawaiian bobtail squid, Euprymna scolopes, and the establishment of this association involves a number of signaling pathways and transcriptional responses between both partners. We report here the first full RNA-Seq dataset representing host-asso...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/1462-2920.13684

    authors: Thompson LR,Nikolakakis K,Pan S,Reed J,Knight R,Ruby EG

    更新日期:2017-05-01 00:00:00

  • PAAR-Rhs proteins harbor various C-terminal toxins to diversify the antibacterial pathways of type VI secretion systems.

    abstract::The type VI secretion system (T6SS) of bacteria plays a key role in competing for specific niches by the contact-dependent killing of competitors. Recently, Rhs proteins with polymorphic C-terminal toxin-domains that inhibit or kill neighboring cells were identified. In this report, we identified a novel Rhs with an M...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/1462-2920.13621

    authors: Ma J,Sun M,Dong W,Pan Z,Lu C,Yao H

    更新日期:2017-01-01 00:00:00

  • Transcriptomic insights into the alternative splicing-mediated adaptation of the entomopathogenic fungus Beauveria bassiana to host niches: autophagy-related gene 8 as an example.

    abstract::Alternative splicing (AS) regulates various biological processes in fungi by extending the cellular proteome. However, comprehensive studies investigating AS in entomopathogenic fungi are lacking. Based on transcriptome data obtained via dual RNA-seq, the first overview of AS events was developed for Beauveria bassian...

    journal_title:Environmental microbiology

    pub_type: 杂志文章

    doi:10.1111/1462-2920.13862

    authors: Dong WX,Ding JL,Gao Y,Peng YJ,Feng MG,Ying SH

    更新日期:2017-10-01 00:00:00