Effects of laser therapy in peripheral nerve regeneration.

Abstract:

OBJECTIVE:The influence of dose of low power lasertherapy (AsGaAl, 830 nm) on the regeneration of the fibular nerve of rats after a crush injury was evaluated by means of the functional gait analysis and histomorphometric parameters. METHODS:Controlled crush injury of the right common fibular nerve, immediately followed by increasing doses (G1: no irradiation; G2: simulated; G3: 5 J/cm(2); G4: 10 J/cm(2); G5: 20 J/cm(2)) laser irradiation directly on the lesion site for 21 consecutive days. Functional gait analysis was carried out at weekly intervals by measuring the peroneal/fibular functional index (PFI). The animals were killed on the 21(st) postoperative day for removal of the fibular nerve, which was prepared for the histomorphometric analysis. RESULTS:The PFI progressively increased during the observation period in all groups, without significant differences between them (p>0.05). The transverse nerve area was significantly wider in group 2 than in groups 3 and 4, while fiber density was significantly greater in group 4 than in all remaining groups. CONCLUSION:The low power AsGaAl laser irradiation did not accelerate nerve recovery with any of the doses used. Level of Evidence I, Therapeutic Studies Investigating the Results of Treatment.

journal_name

Acta Ortop Bras

authors

Sene GA,Sousa FF,Fazan VS,Barbieri CH

doi

10.1590/S1413-78522013000500005

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

266-70

issue

5

eissn

1413-7852

issn

1809-4406

journal_volume

21

pub_type

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