Effects of exercise training programs on physical performance and quality of life in patients with metastatic lung cancer undergoing palliative chemotherapy--a study protocol.

abstract：BACKGROUND:Many studies on the health effects of the glycemic index (GI) are confounded by differences in the intakes of other macronutrients and fibre. Little data exist about the within- and between-subject variability of the GI. OBJECTIVE:Our objectives were therefore (i) to calculate the GI of eight commonly used ...

journal_title：Contemporary clinical trials

authors： Vrolix R,Mensink RP

更新日期：2010-01-01 00:00:00

abstract：:Lumbar spinal stenosis is a common degenerative disorder of the spine in elderly patients that can be effectively treated with decompression surgery in some patients. Radiological findings in the diagnostic work-up of the patients do not always correlate well with clinical symptoms, and guidance about when to proceed ...

journal_title：Contemporary clinical trials

authors： Staub LP,Barz T,Melloh M,Lord SJ,Chatfield M,Bossuyt PM

更新日期：2011-05-01 00:00:00

abstract：:Several randomized trials have found behavior change programs delivered via text messaging to be efficacious to improve preventive health behaviors such as physical activity and stopping smoking; however few have assessed its value in skin cancer prevention or early detection. The HealthyTexts study enrolled 678 parti...

journal_title：Contemporary clinical trials

authors： Janda M,Youl P,Marshall AL,Soyer HP,Baade P

更新日期：2013-05-01 00:00:00

abstract：:The HIV pandemic is a pressing threat to global public health; HIV vaccine development is critical. Clinical evaluation of HIV vaccine candidates differs from the standard therapeutics trial framework primarily due to the fact that healthy individuals are studied. We present an early stage evaluation program developed...

journal_title：Contemporary clinical trials

authors： Moodie Z,Rossini AJ,Hudgens MG,Gilbert PB,Self SG,Russell ND

更新日期：2006-04-01 00:00:00

abstract：:Recruiting sufficient patients within an acceptable time horizon is an issue for most clinical trials and is especially challenging in the field of rare diseases. It is therefore an attractive option to include historical data from previous (pilot) trials in the current study thus reducing the recruitment burden. In c...

journal_title：Contemporary clinical trials

authors： Hees K,Kieser M

更新日期：2017-12-01 00:00:00

abstract：:Patients with Parkinson's disease and related disorders (PDRD) and their families have considerable unmet needs including non-motor symptom management, caregiver support, spiritual wellbeing, advance care planning, and end-of-life care. There is increasing interest in applying palliative care (PC) models to better mee...

journal_title：Contemporary clinical trials

authors： Kluger BM,Katz M,Galifianakis N,Pantilat SZ,Kutner JS,Sillau S,Gritz M,Jones J,Fairclough D,Sumrall M,Hall K,Miyasaki J

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Extant obesity efforts have had a limited impact among low-income underserved children, in part because existing programs are limited in terms of their short duration and low dosage, limited accessibility and sustainability; and failure to address barriers faced by diverse low-income families. METHODS:This ...

journal_title：Contemporary clinical trials

authors： de la Haye K,Fluke M,Laney PC,Goran M,Galama T,Chou CP,Salvy SJ

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:To describe the study protocol of the Multimedia Self-Management (MSM) intervention to prepare patients and family caregivers (FCGs) for lung cancer surgery. DESIGN:The study is a five-year, single site, randomized controlled trial of 160 lung cancer surgery FCG and patient dyads (320 total participants), co...

journal_title：Contemporary clinical trials

authors： Sun V,Raz DJ,Erhunmwunsee L,Ruel N,Carranza J,Prieto R,Ferrell B,Krouse RS,McCorkle R,Kim JY

更新日期：2019-08-01 00:00:00

abstract：:Physical therapy (PT) is a key component of treatment for knee osteoarthritis (OA) and can decrease pain and improve function. Given the expected rise in prevalence of knee OA and the associated demand for treatment, there is a need for models of care that cost-effectively extend PT services for patients with this con...

journal_title：Contemporary clinical trials

authors： Allen KD,Bongiorni D,Walker TA,Bartle J,Bosworth HB,Coffman CJ,Datta SK,Edelman D,Hall KS,Hansen G,Jennings C,Lindquist JH,Oddone EZ,Senick MJ,Sizemore JC,St John J,Hoenig H

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Thousands of people die annually from prescription opioid overdoses; however there are few strategies to ensure patients receive medication risk information at the time of prescribing. OBJECTIVES:To compare the effectiveness of the Emergency Department (ED) Electronic Medication Complete Communication (EMC2...

journal_title：Contemporary clinical trials

authors： McCarthy DM,Courtney DM,Lank PM,Cameron KA,Russell AM,Curtis LM,Kim KA,Walton SM,Montague E,Lyden AL,Gravenor SJ,Wolf MS

更新日期：2017-08-01 00:00:00

abstract：:Chronic insomnia disorder is a prevalent condition and a significant proportion of these individuals also have obstructive sleep apnea (OSA). These two sleep disorders have distinct pathophysiology and are managed with different treatment approaches. High comorbidity rates have been a catalyst for emerging studies exa...

journal_title：Contemporary clinical trials

authors： Crawford MR,Turner AD,Wyatt JK,Fogg LF,Ong JC

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Research demonstrates a link between migraine and obesity. Obesity increases the risk of frequent migraines and is associated with migraine prevalence among reproductive-aged women. These findings are substantiated by several plausible mechanisms and emerging evidence of migraine improvements after surgical ...

journal_title：Contemporary clinical trials

authors： Bond DS,O'Leary KC,Thomas JG,Lipton RB,Papandonatos GD,Roth J,Rathier L,Daniello R,Wing RR

更新日期：2013-05-01 00:00:00

abstract：:Hepatitis C virus (HCV) is a leading cause of chronic liver disease. The natural history of HCV infection is heterogeneous, and a person infected with HCV can clear the virus or progress to a chronic infection. The chronic infection can remain asymptomatic for decades before the development of liver cirrhosis and/or c...

journal_title：Contemporary clinical trials

authors： Kang M,Nicolay U

更新日期：2008-09-01 00:00:00

abstract：:Patients with malignant disease enrolled in trials of thrombotic disorders may experience competing events such as death. The occurrence of a competing event may prevent the thrombotic event from being observed. Standard survival analysis techniques ignore competing risks, resulting in possible bias and distorted infe...

journal_title：Contemporary clinical trials

authors： Parpia S,Julian JA,Thabane L,Lee AY,Rickles FR,Levine MN

更新日期：2011-11-01 00:00:00

abstract：:Clinical trial research is the cornerstone for successful advancement of medicine that provides hope for millions of people in the future. Full transparency in clinical trials may allow independent investigators to evaluate study designs, perform additional analysis of data, and potentially eliminate duplicate studies...

journal_title：Contemporary clinical trials

authors： Logvinov I

更新日期：2014-03-01 00:00:00

abstract：:The 2-in-1 adaptive design [Chen et al. 2018] allows seamless expansion of an ongoing Phase 2 trial into a Phase 3 trial to expedite a drug development program. An intermediate endpoint can be used for the adaptive decision. Under a mild assumption that is expected to generally hold in practice, both the Phase 2 trial...

journal_title：Contemporary clinical trials

authors： Chen C,Li W,Deng Q

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Training non-specialist health workers (NSHWs) at scale is a major barrier to increasing the coverage of depression care in India. This trial will test the effectiveness of two forms of digital training compared to conventional face-to-face training in changing the competence of NSHWs to deliver a brief evid...

journal_title：Contemporary clinical trials

authors： Naslund JA,Tugnawat D,Anand A,Cooper Z,Dimidjian S,Fairburn CG,Hollon SD,Joshi U,Khan A,Lu C,Mitchell LM,Muke S,Nadkarni A,Ramaswamy R,Restivo JL,Shrivastava R,Singh A,Singla DR,Spiegelman D,Bhan A,Patel V

更新日期：2021-01-06 00:00:00

abstract：BACKGROUND:Although individuals with psychiatric disorders are disproportionately affected by cigarette smoking, few outpatient mental health treatment facilities offer smoking cessation services. In this paper, we describe the development of a smartphone-assisted mindfulness smoking cessation intervention with conting...

journal_title：Contemporary clinical trials

authors： Minami H,Brinkman HR,Nahvi S,Arnsten JH,Rivera-Mindt M,Wetter DW,Bloom EL,Price LH,Vieira C,Donnelly R,McClain LM,Kennedy KA,D'Aquila E,Fine M,McCarthy DE,Graham Thomas J,Hecht J,Brown RA

更新日期：2018-03-01 00:00:00

abstract：:Since its introduction in 1974 the use of the term Minimization has been broadened to include other algorithms. All algorithms use patient characteristics to determine the assignment that produces the best overall balance between treatment groups. They differ in whether or not they use all of the data from each previo...

journal_title：Contemporary clinical trials

authors： Taves DR

更新日期：2010-03-01 00:00:00

abstract：:Identifying effective strategies for treating obesity is a clinical challenge and a public health priority. The present study is an innovative test of the relative effectiveness of lottery-based financial incentives and environmental strategies on weight loss and maintenance. The Healthy Weigh study is evaluating the ...

journal_title：Contemporary clinical trials

authors： Glanz K,Shaw PA,Hoffer K,Chung A,Zhu J,Wu R,Huang QE,Choi JR,Volpp KG

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Individuals with serious mental illness (SMI) smoke at disproportionately higher rates than those without SMI, have lifespans 25-32 years shorter, and thus bear an especially large burden of tobacco-related morbidity and mortality. Several recent studies demonstrate that smokers with SMI can successfully qui...

journal_title：Contemporary clinical trials

authors： Hecht J,Rigotti NA,Minami H,Kjome KL,Bloom EL,Kahler CW,Price LH,Levy DE,Carpenter KM,Brown RA

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Despite controversy about paying research subjects, little is known about actual practices in the U.S., including what type of studies offer payment, to what type of subjects, and how amounts are determined. OBJECTIVE:To document current U.S. practices regarding payment to research subjects. METHODS:The pr...

journal_title：Contemporary clinical trials

authors： Grady C,Dickert N,Jawetz T,Gensler G,Emanuel E

更新日期：2005-06-01 00:00:00

abstract：:Slow or insufficient enrollment in clinical research and a high demand for research participants raises questions about the need for and use of incentives to participate, including payment. Much of the available literature on payment to research participants focuses on ethical concerns, and rarely addresses guidelines...

journal_title：Contemporary clinical trials

authors： Dominguez D,Jawara M,Martino N,Sinaii N,Grady C

更新日期：2012-09-01 00:00:00

abstract：INTRODUCTION:Excessive recreational screen time (i.e., screen use for entertainment) is a global public health issue associated with adverse mental and physical health outcomes. Considering the growing popularity of screen-based recreation in adolescents, there is a need to identify effective strategies for reducing sc...

journal_title：Contemporary clinical trials

authors： Babic MJ,Morgan PJ,Plotnikoff RC,Lonsdale C,Eather N,Skinner G,Baker AL,Pollock E,Lubans DR

更新日期：2015-01-01 00:00:00

abstract：:A response-adaptive randomization (RAR) design refers to the method in which the probability of treatment assignment changes according to how well the treatments are performing in the trial. Holding the promise of treating more patients with the better treatments, RARs have been successfully implemented in clinical tr...

journal_title：Contemporary clinical trials

authors： Du Y,Wang X,Jack Lee J

更新日期：2015-01-01 00:00:00

abstract：:College student alcohol use and associated negative consequences are clear public health problems with consequences including damage to self, others, and institutions. This paper describes the protocol of a research study designed to answer a number of important questions in the development of an adaptive preventive i...

journal_title：Contemporary clinical trials

authors： Patrick ME,Boatman JA,Morrell N,Wagner AC,Lyden GR,Nahum-Shani I,King CA,Bonar EE,Lee CM,Larimer ME,Vock DM,Almirall D

更新日期：2020-09-01 00:00:00

abstract：:Suicide remains the 10th leading cause of death among adults in the United States (U.S.). Annually, approximately 30 per 100,000 U.S. military Veterans commit suicide, compared to 14 per 100,000 U.S. civilians. Symptoms associated with suicidality can be treatment resistant and proven-effective pharmaceuticals may hav...

journal_title：Contemporary clinical trials

authors： Marriott BP,Hibbeln JR,Killeen TK,Magruder KM,Holes-Lewis K,Tolliver BK,Turner TH,BRAVO Group.

更新日期：2016-03-01 00:00:00

abstract：INTRODUCTION:Youth in disadvantaged urban areas are frequently exposed to chronic stress and trauma, including housing instability, neighborhood violence, and other poverty-related adversities. These exposures increase risk for emotional, behavioral, and academic problems and ultimately, school dropout. Schools are a p...

journal_title：Contemporary clinical trials

authors： Mendelson T,Clary LK,Sibinga E,Tandon D,Musci R,Mmari K,Salkever D,Stuart EA,Ialongo N

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:In the past 20-30 years, the prevalence of atopic diseases, particularly among children in the Western world, has increased. It has been suggested that Western lifestyle may have reduced the overall exposure to microbial stimulation early in life. The role of the gut flora in this connection has been studied...

journal_title：Contemporary clinical trials

authors： Øien T,Storrø O,Johnsen R

更新日期：2006-08-01 00:00:00

abstract：:The COVID-19 pandemic has substantially impacted the conduct of clinical trials. While initially preparing for a period of time, where it would likely be impossible to supervise trials in the usual way and precautionary measures had to be implemented to care for medication supply and general safety of study participan...

journal_title：Contemporary clinical trials

authors： Großhennig A,Koch A

更新日期：2020-11-01 00:00:00