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Evolution of low molecular weight immunoglobulins. V. Degree of antigenic relationship between the 7S immunoglobulins of mammals, birds, and lower vertebrates to the turkey IgY.

Abstract：

:There are close antigenic relations between the turkey IgY--the dominant 7S Ig of serum--and the corresponding IgY-like Igs of chicken, duck, goose, tortoise, and frog as well as serum or colostral IgA of man and swine. The RIA-systems used for the determination of immunological cross-reactivity among the Ig types consisted of 125-I-labelled turkey IgY and class-specific rabbit anti-turkey IgY antibodies. The results stand in a good agreement with our findings demonstrating strong antigenic relationships between various serum or colostral Igs of IgY and IgA types, respectively, to the chicken IgY. Therefore, the IgY-like Igs seem to be the precursors for the IgA class of mammals.

journal_name

Dev Comp Immunol

journal_title

Developmental and comparative immunology

authors

Hädge D,Ambrosius H

doi

10.1016/0145-305x(86)90027-3

subject

Has Abstract

pub_date

1986-07-01 00:00:00

pages

377-85

issue

3

eissn

0145-305X

issn

1879-0089

pii

0145-305X(86)90027-3

journal_volume

10

pub_type

杂志文章

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