Abstract:
OBJECTIVES:The aim of this comprehensive literature review is to provide recommendations and guidelines for dental implant therapy in patients with a history of radiation in the head and neck region. For the first time, a meta-analysis comparing the implant survival in irradiated and non-irradiated patients was performed. MATERIAL AND METHODS:An extensive electronic search in the electronic databases of the National Library of Medicine was conducted for articles published between January 1990 and January 2013 to identify literature presenting survival data on the topic of dental implants in patients receiving radiotherapy for head and neck cancer. Review and meta-analysis were performed according to Preferred Reporting Items for Systematic Review and Meta-Analyses statement. For meta-analysis, only studies with a mean follow-up of at least 5 years were included. RESULTS:After screening 529 abstracts from the electronic database, we included 31 studies in qualitative and 8 in quantitative synthesis. The mean implant survival rate of all examined studies was 83 % (range, 34-100 %). Meta-analysis of the current literature (2007-2013) revealed no statistically significant difference in implant survival between non-irradiated native bone and irradiated native bone (odds ratio [OR], 1.44; confidence interval [CI], 0.67-3.1). In contrast, meta-analysis of the literature of the years 1990-2006 showed a significant difference in implant survival between non-irradiated and irradiated patients ([OR], 2.12; [CI], 1.69-2.65) with a higher implant survival in the non-irradiated bone. Meta-analysis of the implant survival regarding bone origin indicated a statistically significant higher implant survival in the irradiated native bone compared to the irradiated grafted bone ([OR], 1.82; [CI], 1.14-2.90). CONCLUSIONS:Within the limits of this meta-analytic approach to the literature, this study describes for the first time a comparable implant survival in non-irradiated and irradiated native bone in the current literature. Grafted bone combined with radiotherapy was identified as a negative prognostic factor on implant survival. CLINICAL RELEVANCE:The evolution of implant hardware and improvement of treatment strategies during the last years have affirmed dental implant-supported concepts as a valuable treatment option for patients with a history of radiation in the head and neck region.
journal_name
Clin Oral Investigjournal_title
Clinical oral investigationsauthors
Schiegnitz E,Al-Nawas B,Kämmerer PW,Grötz KAdoi
10.1007/s00784-013-1134-9subject
Has Abstractpub_date
2014-04-01 00:00:00pages
687-98issue
3eissn
1432-6981issn
1436-3771journal_volume
18pub_type
杂志文章,meta分析,评审abstract:OBJECTIVES:The identification of predictors of supragingival biofilm accumulation may improve the results of therapeutic strategies for dental caries and periodontal diseases in general clinical practice. This study aimed to determine predictors of changes in visible plaque (VP) and gingival bleeding (GB) during integr...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2485-z
更新日期:2019-02-01 00:00:00
abstract::The purpose of this 4-day plaque regrowth study was to assess the effect of N-chlorotaurine (NCT) mouth rinses on plaque inhibition and plaque vitality. Eighty volunteers participated in this investigator-blind, randomized, clinical controlled study in parallel groups. No oral hygiene was permitted except rinsing with...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-008-0207-7
更新日期:2009-03-01 00:00:00
abstract:OBJECTIVE:The aim of this in vitro study was to compare fluorescence-aided caries excavation with conventional excavation based on the Martens and Vickers hardness of dentin at the cavity floor after caries removal. MATERIALS AND METHODS:In total, 20 extracted human teeth with dentin caries were bisected through the l...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-0999-y
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:A study is made of the main oral manifestations of patients with rheumatoid arthritis (RA), particularly salivary flow, and of its possible association to periodontal disease. MATERIAL AND METHODS:A prospective comparative study was made of 146 patients (73 with RA and 73 controls), recording pocket depth, c...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-016-1745-z
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to analyze the porosity of three photopolymerizable resin composites: one high-viscous resin composite (Filtek™ P60®, 3 M™ ESPE™), one moderate-viscosity resin composite (Grandio®, VOCO™), and one low-viscous resin composite (Filtek™ Supreme XTE®, 3 M™ ESPE™). MATERIALS AND METHODS...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1139-4
更新日期:2014-07-01 00:00:00
abstract::The aim of this study was to compare different methods of detection of Helicobacter pylori (H. pylori) in the dental plaque of dyspeptic patients. After recording the clinical indices, culture and polymerase chain reaction (PCR) methods were performed on plaque samples, while rapid urease test in addition to these tes...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-007-0104-5
更新日期:2007-09-01 00:00:00
abstract:OBJECTIVES:To provide consensus recommendations on how to intervene in the caries process in adults, specifically proximal and secondary carious lesions. METHODS:Based on two systematic reviews, a consensus conference and followed by an e-Delphi consensus process were held with EFCD/ORCA/DGZ delegates. RESULTS:Managi...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03431-0
更新日期:2020-09-01 00:00:00
abstract::The use of oral implants opened a wide range of prosthetic treatment possibilities in edentulous patients. Although the reported success rates of oral implants are high, failures do occur. This paper reviews the current knowledge about the aetiology, the signs and symptoms and the possible influencing factors of impla...
journal_title:Clinical oral investigations
pub_type: 杂志文章,评审
doi:10.1007/s007840050054
更新日期:1998-09-01 00:00:00
abstract:OBJECTIVE:The objective of this in vitro study was to investigate fracture load, fracture types, and impact of chewing simulation of human molars restored with 3D printed indirect polyetheretherketone (PEEK) inlays and compare these with milled indirect PEEK inlays, direct resin composite fillings, and sound teeth. MA...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03216-5
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVES:The aim of the present retrospective cohort study was to assess the 5-year outcome and survival of secondary root canal treatments (2°RCT), exploring the influence of pre-, intra-, and post-operative variables. MATERIALS AND METHODS:One hundred thirty-two endodontically retreated teeth were radiographically...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-017-2229-5
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVES:This study evaluated the danger zone (DZ) in mesial roots of mandibular molars and the correlation between anatomical references of the DZ and some anatomical landmarks including tooth/root length, depth of mesial and distal grooves, and inter-canal orifices distance. MATERIAL AND METHODS:Twenty-eight mesia...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03686-7
更新日期:2020-11-24 00:00:00
abstract:AIMS:The aims of this double-blind, controlled, crossover study were to assess the influence of food preservatives on in situ dental biofilm growth and vitality, and to evaluate their influence on the ability of dental biofilm to demineralize underlying enamel over a period of 14 days. MATERIALS AND METHODS:Twenty vol...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1053-9
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVES:The purpose of the present study was to evaluate the frequency, locations, and dimensions of mucous retention cysts of the maxillary sinus and analyze potential associated dental pathology. MATERIALS AND METHODS:A total of 156 cone beam computed tomography (CBCT) scans were included in the analysis, resulti...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-017-2206-z
更新日期:2018-04-01 00:00:00
abstract::Acidogenicity and the levels of mutans streptococci (MS) in dental plaque after the use of Lactobacillus rhamnosus GG (LGG) and Lactobacillus reuteri were determined. The study had a randomised, double-blind, crossover design. Thirteen volunteers used tablets containing LGG or a combination of L. reuteri SD2112 and PT...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-011-0584-1
更新日期:2012-06-01 00:00:00
abstract::Oral verrucous carcinoma (OVC) is a rare variant of squamous cell carcinoma with a characteristic morphology and specific behavior. To date, few studies are available focusing the prevalence and clinicopathologic features of the oral verrucous carcinoma in Brazilian population. A total of 3,500 primary oral well-diffe...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-006-0050-7
更新日期:2006-09-01 00:00:00
abstract:OBJECTIVES:The present study aims to investigate the relevance of immunohistochemical p53 expression in carcinomas of the oral cavity and of the head and neck region. Long-term clinical and histopathological follow-up findings as well as HPV status are correlated with the results of this examination. MATERIALS AND MET...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-0939-x
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:Bony reconstruction of jaw defects using the free fibular flap and dental rehabilitation mostly requires insertion of dental implants within the transferred fibula bone. The aim of this paper was to discuss results of the implant stability with data on the possible benefit for the patient's quality of life a...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-015-1487-3
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to assess postoperative pain in a prospective randomized clinical trial comparing two groups, using the Reciproc® system in one group and the ProTaper® rotary system in the other. MATERIAL AND METHODS:The study included 78 male patients, aged 18-64 years (mean age of 26 years), wit...
journal_title:Clinical oral investigations
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00784-015-1692-0
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVES:Ankaferd BloodStopper® (ABS) is an herbal extract which has been used historically as a hemostatic agent in traditional Turkish medicine. ABS comprises of standardized mixture of herbs Thymus vulgaris, Glycyrrhiza glabra, Vitis vinifera, Alpinia officinarum, and Urtica dioica. In addition to its hemostatic e...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-2399-9
更新日期:2018-12-01 00:00:00
abstract:OBJECTIVES:To explore whether a computed tomography (CT) examination of the head and neck region induces biological damage and whether the damage was correlated with the radiation dose. MATERIALS AND METHODS:Peripheral blood was taken from 33 individuals who received head and neck CT examinations. Blood samples were d...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-020-03331-3
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVES:The main goal of the present study was to compare the biomechanical stability of locking plates and conventional miniplate combinations in human mandibles reconstructed with fibular grafts. MATERIALS AND METHODS:A specially developed and well-proven testing device reproduced the in vivo loading conditions o...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-013-1105-1
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVE:This study aimed to prospectively observe gustatory and neurosensory alterations following surgical removal of mandibular third molars. MATERIAL AND METHODS:A prospective clinical study was conducted with patients who required mandibular third molar extraction, recruited from the Division of Oral and Maxillo...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-018-02798-5
更新日期:2019-07-01 00:00:00
abstract::The goal of the study was to develop a validated manual preparation process that conforms to the requirements of validation guidelines. Twelve dental transmission devices from various manufacturers (turbines, handpieces, and contra-angle handpieces) were artificially contaminated with bovine hemoglobin for the test. T...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-010-0425-7
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVES:This work aimed to comparatively evaluate the three modalities of vestibuloplasty around implants in the posterior mandible. MATERIALS AND METHODS:Forty patients who presented with a shallow vestibule and insufficient keratinized gingiva were divided into three groups: apically positioned flap only (APF gro...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-017-2320-y
更新日期:2018-06-01 00:00:00
abstract:OBJECTIVES:The aim of the study was to investigate the caries-preventive effect of newly developed fluoride and fluoride-free toothpastes specially designed for erosion prevention. The hypothesis was that these products might also show superior caries-inhibiting effect than regular fluoride toothpastes, since they were...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-016-1789-0
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVES:This study aimed to estimate the dental age (DA) using the London Atlas, Willems, and Nolla methods and to compare their accuracies. METHODS:The DA was estimated using the aforementioned methods on panoramic radiograms of a total of 919 Eastern Turkish patients aged 6-14 years, of whom 459 were female and 4...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-021-03788-w
更新日期:2021-01-18 00:00:00
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journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-016-1824-1
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVES:Lithium disilicate can easily be machined by CAM techniques in its metasilicate status. Due to slightly inferior material properties, the material is not yet recommended for three-unit fixed dental prosthesis (FDP) as it is the case for the press material up to the second bicuspid. Therefore, the aim of this...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-014-1191-8
更新日期:2014-12-01 00:00:00
abstract::The main objective of this study was to identify the risk factors for the incidence of visible caries experience in a cohort of preschool children living in Flanders. Data were collected from 1,057 children; validated questionnaires on oral health-related behaviour were completed by parents at birth (2003-2004), at ag...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-011-0579-y
更新日期:2012-06-01 00:00:00
abstract::The aim of the present study was to comparatively evaluate DNA damage (micronucleus) and cellular death (pyknosis, karyolysis, and karyorrhexis) in exfoliated oral mucosa cells from smokers and non-smokers submitted to dental X-ray using two anatomic sites: buccal mucosa and lateral border of the tongue. A total of 15...
journal_title:Clinical oral investigations
pub_type: 杂志文章
doi:10.1007/s00784-009-0345-6
更新日期:2010-12-01 00:00:00