Abstract：
OBJECTIVES:The aim of this study was to evaluate the influence of different titanium zirconium (TiZr) alloy surfaces on primary human gingival fibroblasts (HGF) for improved soft tissue integration of dental implants. METHODS:TiZr polished, machined and machined+HCl/H2SO4 acid-etched surfaces were modified by cathodic polarization and/or HNO3/HF acid etching. Contact angle of surfaces was measured. The influence of modified TiZr surfaces on HGF was evaluated through the analysis of cell number, morphology, recovery after a wound (wound healing assay) and the expression of several genes, including matrix metalloproteinase-1 (MMP1) and metallopeptidase inhibitor-1 (TIMP1). RESULTS:Modification of TiZr surfaces decreased its hydrophilicity. Hydride implementation on TiZr surfaces via cathodic polarization increased TIMP1 expression and decreased MMP1/TIMP1 mRNA ratio. Cathodic polarization of machined surfaces promoted cell attachment. Cells on machined and machined+cathodic polarization surfaces grew aligned to the microgrooves whereas on all polished surfaces they grew randomly. Acid etching of polished and machined surfaces did not improve HGF function. CONCLUSIONS:Hydride implementation on TiZr machined surfaces may be used as new dental implant material for improved soft tissue integration. CLINICAL SIGNIFICANCE:Enhancing dental implant surfaces' bioactivity by hydride implementation may promote soft tissue attachment and sealing around the implant and reduce peri-implantitis related to ECM-destruction compared with conventional machined surfaces.
journal_name
J Dentjournal_title
Journal of dentistryauthors
Gómez-Florit M,Xing R,Ramis JM,Taxt-Lamolle S,Haugen HJ,Lyngstadaas SP,Monjo Mdoi
10.1016/j.jdent.2013.11.003subject
Has Abstractpub_date
2014-01-01 00:00:00pages
30-8issue
1eissn
0300-5712issn
1879-176Xpii
S0300-5712(13)00289-3journal_volume
42pub_type
杂志文章abstract：:Listerine, a mouthrinse composed of a mixture of essential oils, was created in 1879 and was originally formulated as a surgical antiseptic. In spite of its known antimicrobial properties it was thought of as a product in search of a use and promoted as a deterrent for halitosis and as a floor cleaner. In the last sev...
journal_title：Journal of dentistry
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abstract：OBJECTIVES:This study aimed to evaluate the effect of low-fluoride toothpastes with calcium glycerophosphate (CaGP) on enamel remineralization in situ. METHODS:Volunteers (n=10) wore palatal devices holding four bovine enamel blocks. The treatments involved 5 experimental phases of 3 days each according to the followi...
journal_title：Journal of dentistry
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abstract：OBJECTIVES:To examine if there is a difference in possible sleep bruxism activity (SB) in subjects with or without attrition-type tooth wear. METHODS:Sixteen individuals with pronounced attritional-type tooth wear were compared with sex and aged matched controls without tooth wear by means of measurement of electromyo...
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pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：2005-02-01 00:00:00
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pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：2010-01-01 00:00:00
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journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2010.04.009
更新日期：2010-07-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.jdent.2011.02.009
更新日期：2011-05-01 00:00:00
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journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2003.11.004
更新日期：2004-03-01 00:00:00
abstract：OBJECTIVES:The purpose of this study was to evaluate the effects of a home bleaching gel containing 15% carbamide peroxide on the surface microhardness of four tooth-colored restorative materials in situ. METHODS:Four types of tooth-colored restorative materials, including a nanocomposite resin (Filtek Z350), a packab...
journal_title：Journal of dentistry
pub_type： 杂志文章,随机对照试验
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更新日期：2008-04-01 00:00:00
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journal_title：Journal of dentistry
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.jdent.2011.10.002
更新日期：2012-01-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/0300-5712(92)90057-j
更新日期：1992-10-01 00:00:00
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journal_title：Journal of dentistry
pub_type： 杂志文章
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更新日期：2013-06-01 00:00:00
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pub_type： 杂志文章
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更新日期：2020-03-01 00:00:00
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journal_title：Journal of dentistry
pub_type： 杂志文章
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pub_type： 杂志文章
doi：10.1016/j.jdent.2007.12.004
更新日期：2008-03-01 00:00:00
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pub_type： 杂志文章
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更新日期：2003-01-01 00:00:00
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journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2018.12.008
更新日期：2019-02-01 00:00:00
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journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2016.01.001
更新日期：2016-04-01 00:00:00
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journal_title：Journal of dentistry
pub_type： 杂志文章
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更新日期：1996-07-01 00:00:00
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journal_title：Journal of dentistry
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.jdent.2014.09.002
更新日期：2015-02-01 00:00:00
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journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2004.07.005
更新日期：2004-11-01 00:00:00
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journal_title：Journal of dentistry
pub_type： 杂志文章
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更新日期：2018-07-01 00:00:00
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journal_title：Journal of dentistry
pub_type： 杂志文章,随机对照试验
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更新日期：2020-05-01 00:00:00
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journal_title：Journal of dentistry
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：2004-01-01 00:00:00
abstract：OBJECTIVES:Traditional mechanical methods of retaining restorative materials have been replaced to a large extent by tooth conserving adhesive restorative techniques. Because adhesives have been evolving so rapidly for the last few years, the timing is right for evaluating the clinical status of present day adhesives. ...
journal_title：Journal of dentistry
pub_type： 杂志文章,评审
doi：10.1016/s0300-5712(96)00070-x
更新日期：1998-01-01 00:00:00
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journal_title：Journal of dentistry
pub_type： 杂志文章
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更新日期：2017-12-01 00:00:00
