Clinicopathologic characteristics and clinical outcomes of esophageal basaloid squamous carcinoma: experience at a single institution.

Abstract:

:This retrospective study investigated the clinicopathologic characteristics and clinical outcomes of esophageal basaloid squamous carcinoma (BSC). Among 190 patients with esophageal carcinoma treated surgically between 1998 and 2011, we identified 9 (4.7%) with BSC. All of the patients were male, with a median age of 65 years. The frequencies of venous invasion, lymphatic invasion, and lymph node metastasis were 56%, 89%, and 67%, respectively. A total of 2 patients were pathologic stage 1, 5 were stage 2, and 2 were stage 3. Tumor recurrence was observed in 56% of the patients. The 5-year survival rate for patients with esophageal BSC was 40%, which was compatible with the figure of 53.8% for control patients (n = 18) with typical squamous cell carcinoma matched for sex, age, tumor location, and pathologic stage (P = 0.45). Although esophageal BSC shows aggressive lymph-vascular invasion and has a high likelihood of recurrence, its prognosis seems identical to that of typical squamous cell carcinoma.

journal_name

Int Surg

journal_title

International surgery

authors

Kumagai Y,Nagata K,Ishiguro T,Haga N,Kuwabara K,Sobajima J,Kumamoto K,Ishibashi K,Baba H,Shimizu M,Tamaru J,Kawano T,Takubo K,Ishida H

doi

10.9738/CC195

subject

Has Abstract

pub_date

2013-10-01 00:00:00

pages

450-4

issue

4

eissn

0020-8868

issn

2520-2456

journal_volume

98

pub_type

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