Abstract:
:We describe a rare case of complete hydatidiform mole with twin live fetus (CHMTF) confirmed by histopathology, flow cytometry and polymerase chain reaction techniques. No malformations were observed, fetal karyotype was normal and β-human chorionic gonadotropin levels were high (>100,000 IU/ml). The patient was informed of the risks and decided to continue with the pregnancy, but at week 15, she had to undergo hysterectomy due to uterine rupture. She subsequently developed persistent trophoblastic disease (PTD) with pulmonary metastases that required treatment with polychemotherapy. Patients with CHMTF should be informed of all known risks, including the considerable risk of PTD, which is similar to or, even higher than that associated with a singleton complete mole. The risk does not appear to be increased by continuing the pregnancy. Because so few series have been published, there is a lack of evidence-based clinical management guidelines. To our knowledge, this is the first report of uterine rupture in CHMTF.
journal_name
Gynecol Obstet Investjournal_title
Gynecologic and obstetric investigationauthors
Sánchez-Ferrer ML,Hernández-Martínez F,Machado-Linde F,Ferri B,Carbonel P,Nieto-Diaz Adoi
10.1159/000355566subject
Has Abstractpub_date
2014-01-01 00:00:00pages
127-33issue
2eissn
0378-7346issn
1423-002Xpii
000355566journal_volume
77pub_type
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000294887
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299256
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journal_title:Gynecologic and obstetric investigation
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doi:10.1159/000184679
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journal_title:Gynecologic and obstetric investigation
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doi:10.1159/000052999
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journal_title:Gynecologic and obstetric investigation
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doi:10.1159/000085535
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journal_title:Gynecologic and obstetric investigation
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doi:10.1159/000443829
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章,多中心研究
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journal_title:Gynecologic and obstetric investigation
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doi:10.1159/000072323
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journal_title:Gynecologic and obstetric investigation
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doi:10.1159/000291848
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journal_title:Gynecologic and obstetric investigation
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doi:10.1159/000292464
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000009949
更新日期:1998-01-01 00:00:00
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000300975
更新日期:1978-01-01 00:00:00
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1159/000338892
更新日期:2012-01-01 00:00:00
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000092857
更新日期:2006-01-01 00:00:00
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299612
更新日期:1981-01-01 00:00:00
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000293338
更新日期:1990-01-01 00:00:00
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299212
更新日期:1983-01-01 00:00:00
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299827
更新日期:1980-01-01 00:00:00
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journal_title:Gynecologic and obstetric investigation
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journal_title:Gynecologic and obstetric investigation
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doi:10.1159/000292595
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000072082
更新日期:2003-01-01 00:00:00
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000294853
更新日期:1992-01-01 00:00:00
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000292330
更新日期:1995-01-01 00:00:00
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000299082
更新日期:1984-01-01 00:00:00
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
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更新日期:2020-01-01 00:00:00
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
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更新日期:2009-01-01 00:00:00
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000010256
更新日期:2000-01-01 00:00:00
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journal_title:Gynecologic and obstetric investigation
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更新日期:1984-01-01 00:00:00
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journal_title:Gynecologic and obstetric investigation
pub_type: 杂志文章
doi:10.1159/000052885
更新日期:2001-01-01 00:00:00