Low differentiated microvascular density and low expression of platelet-derived growth factor-BB (PDGF-BB) predict distant metastasis and poor prognosis in clear cell renal cell carcinoma.

abstract：OBJECTIVES:To assess the activity of baclofen, a potent gamma-aminobutyric acid-ergic agonist, against dysfunctional voiding (DV) and lower urinary tract symptoms (LUTS) in a clinical trial, as DV is a leading cause of LUTS in women, but there is no effective treatment. PATIENTS AND METHODS:We conducted a randomized d...

journal_title：BJU international

authors： Xu D,Qu C,Meng H,Ren J,Zhu Y,Min Z,Kong Y

更新日期：2007-09-01 00:00:00

abstract：UNLABELLED:WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: Prostate cancer has three known clinical risk factors: age, ethnicity and family history. Men's knowledge of prostate cancer is low. This study demonstrates that men rely on family and friends to learn about prostate cancer and help them interpret th...

journal_title：BJU international

authors： Forbat L,Place M,Kelly D,Hubbard G,Boyd K,Howie K,Leung HY

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:To examine, in a retrospective analysis of outcome based on prostate-specific antigen (PSA) levels, whether the 1992 and revised 1997 staging criteria for prostate cancer can be used to predict progression-free survival for patients after radical prostatectomy for pT2 and pT3 prostate cancer. PATIENTS AND ME...

journal_title：BJU international

authors： May F,Hartung R,Breul J

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVES:To describe temporal changes in patient characteristics and outcomes for radical cystectomy (RC) in England between 1995 and 2002, using routinely collected administrative data. PATIENTS AND METHODS:Data were extracted from the Hospital Episode Statistics database of the Department of Health in England, des...

journal_title：BJU international

authors： Nuttall MC,van der Meulen J,McIntosh G,Gillatt D,Emberton M

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:To examine the effect of short-course androgen-suppression therapy (AST) before brachytherapy on all-cause mortality (ACM) rates, stratified by the presence or absence of a history of myocardial infarction (MI) or stroke. AST is used to reduce prostate size to enable men with favourable-risk prostate cancer t...

journal_title：BJU international

authors： Hayes JH,Chen MH,Moran BJ,Braccioforte MH,Dosoretz DE,Salenius S,Katin MJ,Ross R,Choueiri TK,D'Amico AV

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the conservative management of encrusted pyelitis (EP), an infectious disease caused by urea-splitting micro-organisms (Corynebacterium group D2 being the most common), and characterized by stone encrustation of the collecting system. PATIENTS AND METHODS:Four patients (aged 17-62 years) with EP ...

journal_title：BJU international

authors： Meria P,Desgrippes A,Fournier R,Arfi C,Antoine C,Martinat L,Teillac P,Le Duc A

更新日期：1999-08-01 00:00:00

abstract：:What's known on the subject? and What does the study add? The suppressor effect of probiotics on superficial bladder cancer is an observed phenomenon but the specific mechanism is poorly understood. The evidence strongly suggests natural killer (NK) cells are the anti-tumour effector cells involved and NK cell activit...

journal_title：BJU international

authors： Feyisetan O,Tracey C,Hellawell GO

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:To determine the effects of cycling oestrogen in rabbits, as oestrogen is essential for physiological maintenance and integrity of the female urogenital tract. MATERIALS AND METHODS:Changes in circulating oestrogen have marked effects on the bladder of experimental animals, with ovariectomy (Ovx) inducing sm...

journal_title：BJU international

authors： Palmieri K,Mannikarottu AS,Chichester P,Kogan B,Leggett RE,Whitbeck C,Levin RM

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:To investigate the potential role of platelet-derived growth factor-AA (PDGF-AA) and the PDGF-α receptor as prognostic markers in Wilms' tumour. PATIENTS AND METHODS:The expression of PDGF-AA and PDGF-α were investigated using immunohistochemical analysis of 62 Wilms' tumours. Patients were treated with chem...

journal_title：BJU international

authors： Ghanem M,Nijman R,Safan M,van der Kwast T,Vansteenbrugge G

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVES:To analyse the gene expression level of prostate stem cell antigen (PSCA) in human clear cell renal cell carcinoma (CC-RCC) and its relationship with conventional clinicopathological manifestations, to evaluate its prognostic value for patient outcome, and to determine the effect of PSCA on the progression o...

journal_title：BJU international

authors： Elsamman EM,Fukumori T,Tanimoto S,Nakanishi R,Takahashi M,Toida K,Kanayama HO

更新日期：2006-09-01 00:00:00

abstract：OBJECTIVES:To re-evaluate the role of diabetes mellitus (DM) as a risk factor for penile implant infection by exploring the association between glycated haemoglobin (HbA1c) levels and penile implant infection rates and to define a threshold value that predicts implant infection. PATIENTS AND METHODS:We conducted a mul...

journal_title：BJU international

authors： Habous M,Tal R,Tealab A,Soliman T,Nassar M,Mekawi Z,Mahmoud S,Abdelwahab O,Elkhouly M,Kamr H,Remeah A,Binsaleh S,Ralph D,Mulhall J

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:To assess whether the optimal use of combined treatment with chemotherapy and appropriately timed surgical intervention by a specialized team might improve the outcome for patients with poor- and intermediate-prognosis (International Germ Cell Consensus Classification, IGCCC) nonseminomatous germ cell tumours...

journal_title：BJU international

authors： Pentheroudakis G,De Bono JS,Kaye SB,Simpson A,Paul J,Brown I,Pamenter B,Kirk A,Vasey P,Raby N,Kirk D

更新日期：2003-07-01 00:00:00

abstract：UNLABELLED:Study Type - Therapy (RCT) Level of Evidence 1b What's known on the subject? and What does the study add? Men with prostate cancer have higher rates of non-cancer mortality and CV morbidity and some of that excess risk has been attributed to the treatment they receive. ADT is an established treatment option ...

journal_title：BJU international

authors： Nobes JP,Langley SE,Klopper T,Russell-Jones D,Laing RW

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:To describe metastasis-free survival (MFS) in men with prostate-specific antigen (PSA) recurrence following radical prostatectomy, and to define clinical prognostic factors modifying metastatic risk. PATIENTS AND METHODS:We conducted a retrospective analysis of 450 men treated with prostatectomy at a tertiar...

journal_title：BJU international

authors： Antonarakis ES,Feng Z,Trock BJ,Humphreys EB,Carducci MA,Partin AW,Walsh PC,Eisenberger MA

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To determine if there is a significant difference in outcomes of clinical trials funded by industry or not of antimuscarinic medications used to treat overactive bladder (OAB) symptoms and detrusor overactivity (DOA). METHODS:A Medline search was conducted from January 1966 to June 2003 to identify human cli...

journal_title：BJU international

authors： Tulikangas PK,Ayers A,O'Sullivan DM

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of contact laser prostate surgery in the treatment of benign prostatic hyperplasia. PATIENTS AND METHODS:A prospective double-blind randomized controlled trial of transurethral resection of the prostate (TURP) and contact laser prostatectomy was conducted, with an economic evaluation o...

journal_title：BJU international

authors： Keoghane SR,Lawrence KC,Gray AM,Doll HA,Hancock AM,Turner K,Sullivan ME,Dyar O,Cranston D

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the impact of demographic, clinical, treatment and patient-reported parameters on satisfaction with prostate cancer care. Despite the significant worldwide impact of prostate cancer, few data are available specifically addressing satisfaction with treatment-related care. PATIENTS AND METHODS:CaPS...

journal_title：BJU international

authors： Resnick MJ,Guzzo TJ,Cowan JE,Knight SJ,Carroll PR,Penson DF

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVES:ERG-gene rearrangement defines a distinct molecular subtype of PCA with potential biological and clinical implications. To identify a molecular signature reflective of the downstream effects of ERG-mediated transcriptional regulation with prognostic implication in patients with prostate cancer (PCA). MATERI...

journal_title：BJU international

authors： Bismar TA,Alshalalfa M,Petersen LF,Teng LH,Gerke T,Bakkar A,Al-Mami A,Liu S,Dolph M,Mucci LA,Alhajj R

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:To summarize the urological procedures recorded in Hospital Episodes Statistics (HES, 1998-99) and to examine the accuracy of coding and HES. MATERIALS AND METHODS:Data on the 10 commonest urological procedures from the Department of Health website (www.doh.gov.uk/hes) were extracted, summarized and presente...

journal_title：BJU international

authors： Lee F,Patel HR,Emberton M

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:• To evaluate the functional and morphological outcome after open pyeloplasty for ureteropelvic junction obstruction (UPJO) with huge renal pelvis. PATIENTS AND METHODS:• A retrospective review of all cases who underwent pyeloplasty for huge renal pelvis was conducted. • Records were evaluated with respect t...

journal_title：BJU international

authors： Sarhan O,Helmy T,Abou-El Ghar M,Baky MA,El-Assmy A,Dawaba M

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVE:To validate high-sensitivity C-reactive protein (hs-CRP) serum levels as an independent marker for disease-free survival (DFS) in clinically localised clear cell renal cell carcinoma (ccRCC). PATIENTS AND METHODS:In all, 403 consecutive patients with clinically localised (T1-3N0M0) ccRCC treated by radical o...

journal_title：BJU international

authors： de Martino M,Klatte T,Seemann C,Waldert M,Haitel A,Schatzl G,Remzi M,Weibl P

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To evaluate peri-operative peripheral and renal venous plasma levels of vascular endothelial growth factor (VEGF), platelet-derived growth factor type BB (PDGF-BB), transforming growth factor (TGF)-beta1, endostatin, and thrombospondin-1 (TSP-1) in relation to pathological variables and prognosis, as pro- and...

journal_title：BJU international

authors： Klatte T,Böhm M,Nelius T,Filleur S,Reiher F,Allhoff EP

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVES:To study the patterns of care of penile cancer diagnosed in the state of New South Wales (NSW) over a 10 year period and determine factors that are associated with differences in survival. PATIENTS AND METHODS:All invasive penile cancer diagnosed between 2001 and 2009 in NSW, Australia, were identified from...

journal_title：BJU international

authors： Patel MI,Yuminaga Y,Bang A,Lawrentschuk N,Skyring T,Smith DP

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:To determine whether bilateral electrical stimulation (BiES) of the transected pudendal sensory nerves could further enhance the voiding efficiency beyond that produced by unilateral electrical stimulation (UniES) of transected pudendal afferents in rats with urinary retention. MATERIALS AND METHODS:The effi...

journal_title：BJU international

authors： Chen SC,Grill WM,Fan WJ,Kou YR,Lin YS,Lai CH,Peng CW

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVES:To evaluate the relative merits of robotically assisted partial nephrectomy (RPN), using a matched-pair analysis, with laparoscopic PN (LPN). PATIENTS AND METHODS:Between July 2006 and August 2007, 12 patients had RPN for tumour; the outcomes were compared retrospectively with 12 matched patients who had LP...

journal_title：BJU international

authors： Aron M,Koenig P,Kaouk JH,Nguyen MM,Desai MM,Gill IS

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:To quantify the incremental detection rate (DR) of a targeted biopsy in addition to a randomized 10-core biopsy. PATIENTS AND METHODS:This retrospective study analysed 1024 patients who consecutively underwent a four-core real-time elastography (RTE) targeted biopsies in addition to a randomized 10-core tran...

journal_title：BJU international

authors： Salomon G,Drews N,Autier P,Beckmann A,Heinzer H,Hansen J,Michl U,Schlomm T,Haese A,Steuber T,Graefen M,Becker A

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:To present two patients with the tuberous sclerosis complex in whom giant angiomyolipomas (AMLs) were managed conservatively for >20 years, as large (>4 cm) symptomatic AMLs are generally treated with embolization or nephrectomy because of the risks of haemorrhage. PATIENTS AND METHODS:The first patient init...

journal_title：BJU international

authors： Danforth TL,Lane BR,Novick AC

更新日期：2007-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the association of urodynamic variables with continence and upper tract status after reconstruction in patients with classical bladder exstrophy. PATIENTS AND METHODS:Thirty-one patients with bladder exstrophy were assessed 1 year after a modified bladder neck reconstruction. The evaluation inclu...

journal_title：BJU international

authors： Dave S,Grover VP,Agarwala S,Mitra DK,Bhatnagar V

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:To determine whether heat, used in transurethral microwave thermotherapy (TUMT) for benign prostatic hyperplasia and which causes necrotic lesions within the adenoma, induces apoptosis in benign human prostatic stromal cells. Materials and methods Prostatic stromal cells were cultured from benign human prosta...

journal_title：BJU international

authors： Brehmer M,Svensson I

更新日期：2000-03-01 00:00:00

abstract：OBJECTIVES:To determine the most frequent urodynamic observations associated with bladder calculi, and to assess whether the presence of calculi alters these observations. PATIENTS AND METHODS:Fifty patients with bladder stones were included in a prospective study in which two urodynamic tests were used, one at inclus...

journal_title：BJU international

authors： Millán-Rodríguez F,Errando-Smet C,Rousaud-Barón F,Izquierdo-Latorre F,Rousaud-Barón A,Villavicencio-Mavrich H

更新日期：2004-06-01 00:00:00