Analysis of the flavonoid component of bioactive New Zealand mānuka (Leptospermum scoparium) honey and the isolation, characterisation and synthesis of an unusual pyrrole.

Abstract:

:The flavonoid components of New Zealand mānuka (Leptospermum scoparium) honey have been quantified in a series of 31 honeys of varying non-peroxide antibacterial activity to clarify discrepancies between previous studies reported in the literature. Total flavonoid content was 1.16 mg/100 g honey. The principal flavonoids present were pinobanksin, pinocembrin, luteolin and chrysin and together these represented 61% of the total flavonoid content. 1, 2-formyl-5-(2-methoxyphenyl)-pyrrole, which was weakly correlated with the non-peroxide antibacterial activity, was isolated from the flavonoid fraction and separately synthesised. 1 did not display inhibitory activity against Staphylococcus aureus in vitro and thus the origin of the correlation, which is still unknown, is not a direct contribution.

journal_name

Food Chem

journal_title

Food chemistry

authors

Chan CW,Deadman BJ,Manley-Harris M,Wilkins AL,Alber DG,Harry E

doi

10.1016/j.foodchem.2013.04.092

subject

Has Abstract

pub_date

2013-12-01 00:00:00

pages

1772-81

issue

3

eissn

0308-8146

issn

1873-7072

pii

S0308-8146(13)00552-9

journal_volume

141

pub_type

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