Multiple global radiations in tadpole shrimps challenge the concept of 'living fossils'.

abstract：Background:BRCA1 and BRCA2 genes are currently proven to be closely related to high lifetime risks of breast cancer. To date, the closely related genes to BRCA1/2 mutations in breast cancer remains to be fully elucidated. This study aims to identify the gene expression profiles and interaction networks influenced by BR...

journal_title：PeerJ

authors： Li Y,Zhou X,Liu J,Yin Y,Yuan X,Yang R,Wang Q,Ji J,He Q

更新日期：2020-01-21 00:00:00

abstract：:The blacklegged tick Ixodes scapularis is widely distributed in the United States and transmits multiple pathogens to humans, wildlife and domestic animals. Recently, several novel viruses in the family Bunyaviridae (South Bay virus (SBV) and Blacklegged tick phlebovirus (BTPV)) were identified infecting female I. sca...

journal_title：PeerJ

authors： Sakamoto JM,Ng TFF,Suzuki Y,Tsujimoto H,Deng X,Delwart E,Rasgon JL

更新日期：2016-08-11 00:00:00

abstract：:There is a lack of stability in language difficulties across early childhood: most late talkers (LTs) resolve their difficulties by pre-school; and a significant number of children who were not LTs subsequently manifest language difficulties. Greater reliability in predicting individual outcomes is needed, which might...

journal_title：PeerJ

authors： Duff FJ,Nation K,Plunkett K,Bishop D

更新日期：2015-07-23 00:00:00

abstract：:Correct identification of forensically important insects, such as flies in the family Calliphoridae, is a crucial step for them to be used as evidence in legal investigations. Traditional identification based on morphology has been effective, but has some limitations when it comes to identifying immature stages of cer...

journal_title：PeerJ

authors： Yusseff-Vanegas SZ,Agnarsson I

更新日期：2017-07-25 00:00:00

abstract：:To investigate community shelter effects of two invasive decapod species, Hemigrapsus sanguineus and Carcinus maenas, in the Long Island Sound (LIS), we deployed artificial shelters in the intertidal and immediate subtidal zones. These consisted of five groups during the summer: a control, a resident H. sanguineus mal...

journal_title：PeerJ

authors： Hudson DM,Reagan D,Crivello JF

更新日期：2016-07-27 00:00:00

abstract：:The reliability of finite element analysis (FEA) in biomechanical investigations depends upon understanding the influence of model assumptions. In producing finite element models, surface mesh resolution is influenced by the resolution of input geometry, and influences the resolution of the ensuing solid mesh used for...

journal_title：PeerJ

authors： McCurry MR,Evans AR,McHenry CR

更新日期：2015-06-02 00:00:00

abstract：:Irruptions of small consumer populations, driven by pulsed resources, can lead to adverse effects including the decline of indigenous species or increased disease spread. Broad-scale pest management to combat such effects benefits from forecasting of irruptions and an assessment of the optimal control conditions for m...

journal_title：PeerJ

authors： Holland EP,Binny RN,James A

更新日期：2018-12-20 00:00:00

abstract：Objectives:The purpose of this study is to investigate the patterns of complementary and alternative medicine use and its association with time to conventional treatment. Design:A cross-sectional study design was designed. Setting and participants:The study was performed at the Chonburi Cancer Hospital, with chart re...

journal_title：PeerJ

authors： Chotipanich A,Sooksrisawat C,Jittiworapan B

更新日期：2019-06-14 00:00:00

abstract：:Background. Many Long-Term Care (LTC) institutionalized patients are the most frail and functionally dependent among the geriatric population and have significant oral health disparities.They often suffer from dental neglect due to limited access to appropriate professional dental care. These patients have chronic hea...

journal_title：PeerJ

authors： Bilder L,Yavnai N,Zini A

更新日期：2014-06-10 00:00:00

abstract：:Purpose. People with stroke living in the community have an increased prevalence of depression and lower quality of life than healthy older adults. This cross-sectional observational study investigated whether participation in regular exercise was associated with improved mood and quality of life. Methods. We recruite...

journal_title：PeerJ

authors： McDonnell MN,Mackintosh SF,Hillier SL,Bryan J

更新日期：2014-03-27 00:00:00

abstract：:Structural variants (SVs) are an important class of genetic variation implicated in a wide array of genetic diseases including cancer. Despite the advances in whole genome sequencing, comprehensive and accurate detection of SVs in short-read data still poses some practical and computational challenges. We present sv-c...

journal_title：PeerJ

authors： Kuzniar A,Maassen J,Verhoeven S,Santuari L,Shneider C,Kloosterman WP,de Ridder J

更新日期：2020-01-06 00:00:00

abstract：Background:E-health technology applications are essential tools of modern information technology that improve quality of healthcare delivery in hospitals of both developed and developing countries. However, despite its positive benefits, studies indicate that the rate of the e-health adoption in some developing countri...

journal_title：PeerJ

authors： Zayyad MA,Toycan M

更新日期：2018-03-01 00:00:00

abstract：:Limestone karsts of Southeast Asia can harbor high levels of endemism, but are highly fragmented, increasingly threatened, and their biodiversity is often poorly studied. This is true of the Padawan Limestone Area of Sarawak, Malaysia, home to the endemic Artocarpus annulatus, the closest known wild relative of two im...

journal_title：PeerJ

authors： Dickinson L,Noble H,Gardner E,Puad ASA,Zakaria WNFW,Zerega NJC

更新日期：2020-09-21 00:00:00

abstract：:Because cancer evolution underlies the therapeutic difficulties of cancer, it is clinically important to understand the evolutionary dynamics of cancer. Thus far, a number of evolutionary processes have been proposed to be working in cancer evolution. However, there exists no simulation model that can describe the dif...

journal_title：PeerJ

authors： Niida A,Hasegawa T,Innan H,Shibata T,Mimori K,Miyano S

更新日期：2020-04-08 00:00:00

abstract：Background:The exoskeleton of an insect could be an important factor in the success of its evolutionary process. This reaches its maximum expression in beetles, which constitute the most diversified animal taxon. The involvement in the management of environmental radiation could be one of the most important functions o...

journal_title：PeerJ

authors： Cuesta E,Lobo JM

更新日期：2019-11-25 00:00:00

abstract：:The Asian citrus psyllid (ACP), Diaphorina citri Kuwayama, is one of the most serious citrus pests worldwide due to its role as vector of huanglongbing or citrus greening disease. While some optimal plant species for ACP oviposition and development have been identified, little is known of the influence of host plants ...

journal_title：PeerJ

authors： Paris TM,Allan SA,Hall DG,Hentz MG,Hetesy G,Stansly PA

更新日期：2016-11-03 00:00:00

abstract：:Afrotheria is a strongly supported clade within placental mammals, but morphological synapomorphies for the entire group have only recently come to light. Soft tissue characters represent an underutilized source of data for phylogenetic analysis, but nonetheless provide features shared by some or all members of Afroth...

journal_title：PeerJ

authors： Brocklehurst RJ,Crumpton N,Button E,Asher RJ

更新日期：2016-04-12 00:00:00

abstract：:The shifting baseline syndrome describes a gradual lowering of human cognitive baselines, as each generation accepts a lower standard of resource abundance or size as the new norm. There is strong empirical evidence of declining trends of abundance and body sizes of marine fish species reported from docks and markets....

journal_title：PeerJ

authors： Francis FT,Howard BR,Berchtold AE,Branch TA,Chaves LCT,Dunic JC,Favaro B,Jeffrey KM,Malpica-Cruz L,Maslowski N,Schultz JA,Smith NS,Côté IM

更新日期：2019-02-15 00:00:00

abstract：:Trees in the Morus genera belong to the Moraceae family. To better understand the species status of genus Morus and to provide information for studies on evolutionary biology within the genus, the complete chloroplast (cp) genomes of M. cathayana and M. multicaulis were sequenced. The plastomes of the two species are ...

journal_title：PeerJ

authors： Kong WQ,Yang JH

更新日期：2017-03-08 00:00:00

abstract：Background and Purpose:Several studies have proposed that the advanced lung cancer inflammation index (ALI), a new inflammation-related index, can be used for the prognosis assessment of various malignancies. However, few studies have reported its prognostic value in colorectal cancer (CRC). Therefore, this study explo...

journal_title：PeerJ

authors： Xie H,Huang S,Yuan G,Kuang J,Yan L,Wei L,Tang S,Gan J

更新日期：2020-10-08 00:00:00

abstract：:Bacterial populations present in Hg-rich environments have evolved biological mechanisms to detoxify methylmercury and other organometallic mercury compounds. The most common resistance mechanism relies on the H(+)-assisted cleavage of the Hg-C bond of methylmercury by the organomercurial lyase MerB. Although the init...

journal_title：PeerJ

authors： Silva PJ,Rodrigues V

更新日期：2015-07-28 00:00:00

abstract：Background:Epidemiological surveillance of HIV infection in Japan involves two technical problems for directly applying a classical backcalculation method, i.e., (i) all AIDS cases are not counted over time and (ii) people diagnosed with HIV have received antiretroviral therapy, extending the incubation period. The pre...

journal_title：PeerJ

authors： Nishiura H

更新日期：2019-01-15 00:00:00

abstract：:It is assumed that the sequencing of ribosomes better reflects the active microbial community than the sequencing of the ribosomal RNA encoding genes. Yet, many studies exploring microbial communities in various environments, ranging from the human gut to deep oceans, questioned the validity of this paradigm due to th...

journal_title：PeerJ

authors： Šťovíček A,Cohen-Chalamish S,Gillor O

更新日期：2019-10-25 00:00:00

abstract：Background:Non-small cell lung cancer (NSCLC) is one of the most common malignant tumors in the world, and it has become the leading cause of death of malignant tumors. However, its mechanisms are not fully clear. The aim of this study is to investigate the key genes and explore their potential mechanisms involving in ...

journal_title：PeerJ

authors： Zhang L,Peng R,Sun Y,Wang J,Chong X,Zhang Z

更新日期：2019-12-12 00:00:00

abstract：:Rhizoctonia solani causes the disease peanut sheath blight, involving symptoms of maceration and necrosis of infected tissue, mainly caused by cell-wall-degrading enzymes (CWDEs). This study investigated the production of CWDEs including polygalacturonase (PG), polymethyl-galacturonase (PMG), cellulase (Cx) and β-gluc...

journal_title：PeerJ

authors： Xue CY,Zhou RJ,Li YJ,Xiao D,Fu JF

更新日期：2018-09-05 00:00:00

abstract：BACKGROUND:As one of the highest forest ecosystems in the world, Polylepis forests are recognized both as center of endemism and diversity along the Andes and as an ecosystem under serious threat from habitat loss, fragmentation, and climate change due to human activities. Effective conservation efforts are limited, in...

journal_title：PeerJ

authors： Sevillano-Ríos CS,Rodewald AD

更新日期：2017-04-27 00:00:00

abstract：:What are the greatest sizes that the largest marine megafauna obtain? This is a simple question with a difficult and complex answer. Many of the largest-sized species occur in the world's oceans. For many of these, rarity, remoteness, and quite simply the logistics of measuring these giants has made obtaining accurate...

journal_title：PeerJ

authors： McClain CR,Balk MA,Benfield MC,Branch TA,Chen C,Cosgrove J,Dove AD,Gaskins LC,Helm RR,Hochberg FG,Lee FB,Marshall A,McMurray SE,Schanche C,Stone SN,Thaler AD

更新日期：2015-01-13 00:00:00

abstract：Background:The ongoing change in climate is predicted to exert unprecedented effects on Earth's biodiversity at all levels of organization. Biological conservation is important to prevent biodiversity loss, especially for species facing a high risk of extinction. Understanding the past responses of species to climate c...

journal_title：PeerJ

authors： Bai Y,Wei X,Li X

更新日期：2018-01-16 00:00:00

abstract：:Background. Research addressing distinctions and similarities between people's malevolent character traits (i.e., the Dark Triad: Machiavellianism, narcissism, and psychopathy) has detected inconsistent linear associations to temperament traits. Additionally, these dark traits seem to have a common core expressed as u...

journal_title：PeerJ

authors： Garcia D,Rosenberg P

更新日期：2016-02-08 00:00:00

abstract：:Vitellogenin has been proposed to regulate division of labor and social organization in social insects. The red imported fire ant (Solenopsis invicta) harbors four distinct, adjacent vitellogenin genes (Vg1, Vg2, Vg3, and Vg4). Contrary to honey bees that have a single Vg ortholog as well as potentially fertile nurses...

journal_title：PeerJ

authors： Hawkings C,Tamborindeguy C

更新日期：2018-05-28 00:00:00