Two cases of lupus vulgaris in childhood and review of the clinical challenges.

Abstract:

BACKGROUND:Lupus vulgaris (LV) is the most common form of cutaneous tuberculosis (TB) in Europe, nevertheless the overall incidence is low. It constitutes about 1.5% of all extra-pulmonary cases worldwide. A slight raise in TB incidence rates among children was recently registered in Germany, which can be explained by the increased immigration. PATIENTS AND METHODS:We present 2 cases of immigrated children who were diagnosed with Lupus vulagris, both clinically and histopathologically. Although the symptoms and the duration of the skin lesions were very different, both patients had a non-healing skin ulceration.In our cases cultures of the skin biopsy were positive for Mycobacterium tuberculosis and the lesions showed marked improvement in response to antituberculous treatment. In the first patient, it took 6 years between occurrence of skin lesions and final diagnosis. The second patient had an extracutaneous focus, namely abdominal TB. CONCLUSION:We report our experience and emphasize on recent advances in the diagnosis and treatment of paediatric skin TB.

journal_name

Klin Padiatr

journal_title

Klinische Padiatrie

authors

Striegel AK,Nazzal R,Fabri M,Rietschel E,Dötsch J,Mauch C,Tantcheva-Poor I

doi

10.1055/s-0033-1343412

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

40-3

issue

1

eissn

0300-8630

issn

1439-3824

journal_volume

226

pub_type

杂志文章,评审
  • Laryngomalacia and complicated, life-threatening mTOR-positive Kaposiform hemangioendothelioma cured by Supraglottoplasty and sirolimus.

    abstract::The therapy of complicated Kaposiform hemangioendothelioma (KHE) is still difficult. We present the first case of laryngomalacia with simultaneous mammalian target of Rapamycin (mTOR)-positive KHE of the neck and thoracic inlet and concurrent Kasabach-Meritt Phenomenon (KMP) in an 11-month-old boy suffering life-threa...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0034-1372587

    authors: Schroeder U,Lauten M,Stichtenoth G,Gebhard MP,Buchholz M,Kaiser MM

    更新日期:2014-11-01 00:00:00

  • Radio-immunodetection of myosarcoma using 111indium antimyosin.

    abstract::Radio-labelled antimyosin-monoclonal antibodies (AMA) have been introduced to demonstrate myocardial necrosis after cardiac infarction or in cardiac allograft transplants. As rhabdomyosarcoma (RMS) and leiomyosarcoma (LMS) are tumors of myogenic origin, thus often containing myosin, we decided to use the 111In-labelle...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2007-1025525

    authors: Koscielniak E,Reuland P,Schilling F,Feine U,Treuner J

    更新日期:1990-07-01 00:00:00

  • [Neonatal form of a nonketotic hyperglycinemia in consanguinous parents].

    abstract::This is a report of the neonatal form of nonketotic hyperglycinemia with rapid progressing neurological symptoms, respiratory distress and seizures. The EEG pattern is characteristic, the ratio of cerebrospinal fluid to plasma glycine abnormally high. The result of cranial computerized tomography demonstrates also in ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2007-1025473

    authors: Plöchl E,Rittinger O,Doringer E,Laubichler W

    更新日期:1991-11-01 00:00:00

  • [Transcutaneous measurements of pO2 in newborns with RDS (author's transl)].

    abstract::pO2 was measured transcutaneously (commercially available Clark Electrode, Bioelectronics Roche) with two different electrode temperatures in new born infants. The correlation between paO2 (arteria radialis) and ptcO2 was bad (r= 0,74) with electrode temperature of 42 degrees C. When the electrode was heated to 44 deg...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:

    authors: Haschke F,Häckel F,Hohenauer L

    更新日期:1976-01-01 00:00:00

  • [Therapy of choroid plexus carcinoma in childhood. Case report and review of the literature].

    abstract::Carcinomas of the plexus choroideus (PCC) represent the rare malignant variety of plexus choroideus papillomas and take a particularly unfavourable course. Tumors of the plexus choroideus account for about 2-4% of all primary brain tumors in children and 0.5% of those in adults. The PCC is more frequent in children th...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章,评审

    doi:10.1055/s-2008-1046511

    authors: Peschgens T,Stollbrink-Peschgens C,Mertens R,Völker A,Thron A,Heimann G

    更新日期:1995-03-01 00:00:00

  • [Neurenteric cyst of the mediastinum--case report and review of the literature].

    abstract::A case of an infant with a mediastinal neurenteric cyst is used to review this rare entity. By definition a neurenteric cyst is the combination of an entodermal cyst with a vertebral dysplasia. Neurenteric cysts are located in the posterior mediastinum, preferentially on the right side. In a third of the patients thes...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1026749

    authors: Köster B,Emons D,Kunath U,Födisch HJ

    更新日期:1987-01-01 00:00:00

  • [Identification of bacterial antigens in patients pretreated with antibiotics using counter-current immunoelectrophoresis (author's transl)].

    abstract::The article describes the method of counter-current immunoelectrophoresis as a rapid and safe technique for the identification of bacterial antigens in body fluids. This technique has proved very useful especially in patients who had been pretreated with antibiotics, since the culture yields are usually negative in su...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1034426

    authors: Storm W

    更新日期:1981-01-01 00:00:00

  • [Bottom-up analysis of the case costs of stem cell transplantation and selected chemotherapies].

    abstract:BACKGROUND:Up to now, reliable data has not been available on the actual costs of treating oncological patients. However, such data material is urgently required in view of the institution of the health service reform with the concomitant introduction of the G-DRG remuneration system. PATIENTS:The medical services and...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2003-39379

    authors: Stäbler W,Wagner B

    更新日期:2003-05-01 00:00:00

  • [Analysis of a Family-centred Care Programme with Follow-up Home-visits in Neonatology - In Times of the Directive from G-BA].

    abstract:BACKGROUND:Marked progress in neonatology changed care of very preterm infants (VLBW) over the last decades - but also the attitude towards family-centred care (FCC). With the directive of the German Federal Joined Committee (G-BA), politicians recognize the necessity of neonatal FCC. AIM:To evaluate time and personne...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0042-102787

    authors: Hüning BM,Reimann M,Sahlmen S,Leibold S,Nabring JC,Felderhoff-Müser U

    更新日期:2016-07-01 00:00:00

  • Ceftriaxone alone or in Combination with Teicoplanin in the Management of Febrile Episodes in Neutropenic Children and Adolescents with Cancer on an Outpatient Base.

    abstract:STUDY OBJECTIVE:This study prospectively investigated the outpatient once daily therapy with ceftriaxone alone or if necessary in combination with teicoplanin, in the treatment of infections in children and adolescents with chemotherapy-induced neutropenia or aplastic anemia. PATIENTS:42 patients 1-22 years of age suf...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2007-1025240

    authors: Preis S,Jürgens H,Friedland C,Oudekotte-David AA,Thomas L,Göbel U

    更新日期:1993-07-01 00:00:00

  • Diabetes in Patients with ß-thalassemia or other Hemoglobinopathies - Analysis from the DPV Database.

    abstract::Background: Diabetes mellitus is a common endocrinopathy in patients with thalassemia major, but the occurrence of hemoglobinopathies is rare in Germany and Western Europe. The longitudinal German-Austrian DPV (Diabetes Patienten Verlaufsdokumentation) registry allows a comprehensive characterization of this group of ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0042-111691

    authors: Warncke K,Konrad K,Kohne E,Hammer E,Ohlenschläger U,Herrlinger S,Jäger A,Holl RW

    更新日期:2016-11-01 00:00:00

  • Cerebellar mutism syndrome.

    abstract::Since 1980, a growing number of pediatric patients with mutism following posterior fossa surgery have been recognized. This syndrome typically affects children and in rare cases young adults who become mute one or two days after tumor operation but do not show disturbances of consciousness or language comprehension. T...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1043886

    authors: Janssen G,Messing-Jünger AM,Engelbrecht V,Göbel U,Bock WJ,Lenard HG

    更新日期:1998-07-01 00:00:00

  • [Transmission of the human immunodeficiency virus by a dry heat-treated Factor VIII concentrate?].

    abstract::Short presentation of the common procedures to avoid transmission of human-immunodeficiency-virus (HIV) by hemoderivates especially clotting-factor-preparations. The stepwise seroconversion (ELISA, IFT, Western-blot) of HIV is shown in a 7 5/12 ys old boy with hemophilia A after administration of a dry-heated factor V...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1033736

    authors: Weisser J

    更新日期:1988-09-01 00:00:00

  • [Treatment and results of the first relapse of acute lymphatic leukemia in childhood (author's transl)].

    abstract::In our experience the prognosis of hematological relapse in patients with acute lymphatic leukemia treated according to the Pinkel programme is very bad. It may be a little better for patients in whom relapse occurred after the end of therapy and who were submitted to intensified cytostatic treatment. The chances for ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:

    authors: Gröbe H,Schellong G

    更新日期:1977-01-01 00:00:00

  • Easy removal of a large mucus plug with a flexible paediatric bronchoscope after administration of rhDNase (Pulmozyme).

    abstract::Mucoid impaction and plastic bronchitis are relatively rare disorders affecting patients of any age. Here we report the case of mucoid impaction developing in a four-year-old child as a complication of pneumonic infection treated four weeks prior. p.a. chest X-ray and fiberoptic bronchoscopy showed atelectasis and the...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2005-836608

    authors: Kamin W,Klär-Hlawatsch B,Truebel H

    更新日期:2006-03-01 00:00:00

  • [Fertility Preservation in Prepubertal und Pubertal Children and Adolescents].

    abstract:BACKGROUND:Due to rising survival rates in cancer and autoimmune diseases fertility preservation before gonadotoxic therapies has become increasingly important. Although fertility can be significantly affected by gonadotoxic therapies, the possibility of fertility preservation during childhood has not been sufficiently...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0044-100396

    authors: Sänger N,Jarisch A,Ochsendorf F,Klingebiel T,Liebenthron J,Kliesch S,von Wolff M

    更新日期:2018-02-08 00:00:00

  • Tumorangiogenesis: a network of cytokines.

    abstract::During angiogenesis new blood vessels sprout from an existing vascular bed. This is a prerequisite for tumor growth beyond a certain size and for metastasis formation. Tumors produce a number of cytokines. The development of in vivo bio-assays for angiogenesis and in vitro analysis of endothelial cells permits charact...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章,评审

    doi:10.1055/s-2008-1043960

    authors: Hotfilder M,Nowak-Göttl U,Wolff JE

    更新日期:1997-07-01 00:00:00

  • Diagnostic value of immature myeloid information in early-onset bacterial infection in term and preterm neonates.

    abstract:BACKGROUND:For quick detection of neonatal early-onset bacterial infection (EOBI) pro-inflammatory cytokines like Interleukin-6 (IL-6) and Interleukin-8 (IL-8) in combiantion with C-reactive Protein (CRP) have been used. Automated determination of immature myeloid information (IMI) seems to be an additional useful tool...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0034-1395552

    authors: Neunhoeffer F,Dabek MT,Renk H,Rimmele P,Poets C,Goelz R,Orlikowsky T

    更新日期:2015-03-01 00:00:00

  • [Determination and clinical significance of colloid osmotic pressure in pediatric patients].

    abstract::The clinical significance of colloid osmotic pressure (COP) in transcapillary fluid exchange and water homeostasis in health and disease is described. Under pathophysiological circumstances measurement of COP should be preferred to COP value calculation. After extensive COP experiences in critically ill adults and num...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1034010

    authors: Abel M

    更新日期:1985-09-01 00:00:00

  • [Creatine kinase "NAC-activated": reference values for children (author's transl)].

    abstract::Reference values for 327 children aged between 1 day and 15 years are given for the revised standard method for the determination of serum creatine kinase (CK) activity by activation with N-acetylcysteine (NAC). No sex-dependence could be observed, but CK activity was found to vary markedly with age. The following val...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1035606

    authors: Kupke IR,Tritschler W,Kather B,Bablok W

    更新日期:1980-07-01 00:00:00

  • Children and adolescents with fetal alcohol syndrome (FAS): better social and emotional integration after early diagnosis.

    abstract:BACKGROUND:Alcoholism during pregnancy is one of the most common factors in western societies causing persisting congenital and multiple physical as well as neurological impairments. Finding the diagnosis at first sight puts medical professionals into a demanding situation. Therefore the objective of this study was to ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0031-1299682

    authors: Alex K,Feldmann R

    更新日期:2012-03-01 00:00:00

  • [Children and Adolescents with Asthma Differ in Lung Function Parameters and Exhaled NO from Children and Adolescents with Obesity].

    abstract:BACKGROUND:The prevalence of asthma and overweight/obesity in children and adolescents is continuously increasing over the last decades. It remains unclear if overweight/obesity raises the risk of developing asthma or if an uncontrolled asthma increases the risk of developing overweight/obesity by restricting physical ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0042-102254

    authors: Schmauck-Gómez JS,Menrath I,Kaiser MM,Herz A,Kopp MV

    更新日期:2016-07-01 00:00:00

  • [Effects of self-adapting G-DRG system 2004 to 2006 on in-patient services payment in pediatric hematology and oncology patients of a university hospital].

    abstract:BACKGROUND:Reimbursement of inpatient treatment by daily constant charges is replaced by diagnosis- and procedure-related group system (G-DRG) in German acute care hospitals excerpt for psychiatry since 2004. Re-designs of G-DRG system were undertaken in 2005 and 2006. Parallel to implementation requirement- and resour...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2006-942274

    authors: Christaras A,Schaper J,Strelow H,Laws HJ,Göbel U

    更新日期:2006-11-01 00:00:00

  • Imaging of chronic inflammatory bowel disease with 18F-FDG PET in children and adolescents.

    abstract::Standard for diagnosis of inflammatory bowel disease (IBD) is the endoscopy of the stomach and the intestine. Aim of this study was to determine the value of 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) in pediatric patients with mild to moderate IBD.We included 23 children and adolescents between 8 a...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0033-1334878

    authors: Berthold LD,Steiner D,Scholz D,Alzen G,Zimmer KP

    更新日期:2013-07-01 00:00:00

  • Is there a predictive value of EEG and MRI after a first afebrile seizure in children?

    abstract:BACKGROUND:After a first afebrile seizure, EEG in addition to cMRI is recommended for pediatric patients. Once indications requiring immediate treatment are excluded, it is of interest to determine if the results provide a prognostic tool for seizure relapses. METHODS:Patients aged between 1 month and 18 years who had...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0034-1394421

    authors: Tews W,Weise S,Syrbe S,Hirsch W,Viehweger A,Merkenschlager A,Bertsche A,Kiess W,Bernhard MK

    更新日期:2015-03-01 00:00:00

  • Bleeding and thrombosis in children with acute lymphoblastic leukaemia, treated according to the ALL-BFM-90 protocol.

    abstract::A multi-center retrospective survey was conducted to evaluate the incidence and types of hemostatic complications occurring in children with acute lymphoblastic leukemia (ALL) during treatment according to the ALL-BFM-90 treatment protocol. All of the BFM-treatment centers (n = 77) were approached and a 95% response r...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章,多中心研究

    doi:10.1055/s-2008-1043788

    authors: Sutor AH,Mall V,Thomas KB

    更新日期:1999-07-01 00:00:00

  • [Interferons--biologic principles and clinical uses].

    abstract::Interferons are components of the nonspecific defense system. Their most prominent biological roles are the antiviral, the antiproliferative, and the immunoregulatory activities. However, their primary functions within the organism remains to be determined. Three types of IFNs have been described so far (IFN alpha, IF...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1033980

    authors: Jacobsen H,Kirchner H

    更新日期:1985-07-01 00:00:00

  • [Pneumatocele after hydrocarbon aspiration].

    abstract::Report of accidental ingestion and aspiration of lamp oil of a boy aged 16 months. He develops in a few hours a severe pneumonitis with tachycardia. Echocardiography shows diminished contractability. After losing his symptoms, the chest x-rays on the 13th day show bilateral pneumatoceles. The course remains asymptomat...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1043916

    authors: Leuchter D,Stübecke W,Oberschulte-Beckmann D

    更新日期:1998-11-01 00:00:00

  • Symptom patterns in childhood arterial ischemic stroke: Analysis of a population-based study in Germany.

    abstract:HINTERGRUND: Die zeitliche Verzögerung zwischen Symptombeginn und Diagnose ist eine Herausforderung in der Behandlung von Kindern mit arteriell ischämischem Schlaganfall. Frühere Studien zur klinischen Präsentation beschäftigten sich v. a. mit kumulativen Symptomen. ZIELSETZUNG: Ziel dieser Studie ist es, mögliche Sym...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/a-0684-9794

    authors: Gerstl L,Weinberger R,von Kries R,Heinen F,Sebastian Schroeder A,Veronika Bonfert M,Borggräfe I,Tacke M,Vill K,N Landgraf M,Kurnik K,Olivieri M

    更新日期:2018-10-01 00:00:00

  • A Case of Hemophagocytic Lymphohistiocytosis following Refractory Kawasaki Disease.

    abstract::Hemophagocytic lymphohistiocytosis (HLH) is a systemic inflammatory disorder characterized by uncontrolled histiocytic proliferation, hemophagocytosis, macrophage activation, and up-regulation of inflammatory cytokines (Grom AA., Current opinion in rheumatology 2003; 15: 587-590). HLH is usually divided into two types...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/a-1110-7303

    authors: Li Y,Wang Y,Li S,Liu M,Wang D,Xu C,Zhang L

    更新日期:2020-02-25 00:00:00