Abstract：
:We developed a computational model of lung parenchyma, which is comprised of individual alveolar chamber models. Each alveolus is modeled by a truncated octahedron. Considering the force balance between the elastin and collagen fibers laying on the alveolar membrane and the pressures acting on the membrane, we computed the deformations of the parenchyma with a finite element method. We focused on the effect of surfactant on the force of parenchymal tethering an airway. As the lung inflates, the parenchyma becomes stiffer and the tethering force becomes stronger. As the alveolar surfactant concentration is reduced, the lung volume at a fixed alveolar pressure decreases, and thus, the tethering force becomes weaker. The distortion of parenchyma caused by the deformation of an airway extends widely around the airway. The displacement of parenchyma decays with distance from the airway wall, but deviates from the prediction based on a theory for a continuum material. Using results obtained from the present lung parenchyma model, we also developed a simple 1-dimensional model for parenchyma tethering force on an airway, which could be utilized for the analysis of liquid/gas transports in an axis-symmetric elastic airway. The effective shear modulus was calculated from the pressure-volume relation of parenchyma. By manipulating the pressure-volume curve, this simple model may be used to predict the parenchyma tethering force in diseased lungs.
journal_name
J Biomechjournal_title
Journal of biomechanicsauthors
Fujioka H,Halpern D,Gaver DP 3rddoi
10.1016/j.jbiomech.2012.11.031subject
Has Abstractpub_date
2013-01-18 00:00:00pages
319-28issue
2eissn
0021-9290issn
1873-2380pii
S0021-9290(12)00683-5journal_volume
46pub_type
杂志文章abstract：:A finite element model was used to investigate the counter-intuitive experimental observation that some regions of the aponeuroses of a loaded and contracting muscle may shorten rather than undergo an expected lengthening. The model confirms the experimental findings and suggests that pennation angle plays a significa...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2010.01.005
更新日期：2010-05-07 00:00:00
abstract：:This paperwork deals with the obtaining and characterisation of new acrylic cements for bone surgery. The final mixture of cement contains derivatives of methacryloyloxyethyl phosphate, methacrylic acid or 2-acrylamido-2-methyl-1-propane sulphonic acid. The idea of using these monomers is sustained by their ability to...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2007.05.002
更新日期：2007-01-01 00:00:00
abstract：:Osteocytes actively regulate bone modeling and remodeling, direct skeletal mineralization, and regulate calcium/phosphate homeostasis and extracellular matrix metabolism; yet the specific role of osteocytes in maintaining bone structural integrity and strength is unknown. Studies have shown that the density of osteocy...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2008.01.017
更新日期：2008-01-01 00:00:00
abstract：:We previously developed a load-adaptive bone modelling and remodelling simulation model that can predict changes in the bone micro-architecture as a result of changes in mechanical loading or cell activity. In combination with a novel algorithm to estimate loading conditions, this offers the possibility for patient-sp...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2012.06.031
更新日期：2012-09-21 00:00:00
abstract：:Although we sometimes use the intrasynovial tendon allograft as a donor, the gliding ability of allograft prepared by lyophilization is significantly decreased. The gliding ability of the grafted tendon after tendon reconstruction is very important because the high gliding resistance causes more adhesion and leads to ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2010.12.030
更新日期：2011-06-03 00:00:00
abstract：:Muscle fatigue alters neuromuscular responses. This may lead to increased sensitivity to perturbations and possibly to subsequent injury risk. We studied the effects of muscle fatigue on movement stability during a repetitive upper extremity task. Twenty healthy young subjects performed a repetitive work task, similar...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2009.11.001
更新日期：2010-03-22 00:00:00
abstract：:Musculo-skeletal modeling could play a key role in advancing our understanding of the healthy and pathological spine, but the credibility of such models are strictly dependent on the accuracy of the anatomical data incorporated. In this study, we present a complete and coherent musculo-skeletal dataset for the thoraci...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2017.04.003
更新日期：2017-06-14 00:00:00
abstract：:The force maintained following stretching of an active muscle exceeds the isometric force at the same muscle length. This residual force enhancement (RFE) is different for various muscles. It is currently unknown whether training induces changes in RFE. Weightlifters perform a large number of eccentric contractions du...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2016.05.017
更新日期：2016-07-05 00:00:00
abstract：:The literature contains many measurements of the fatigue properties of compact bone, but these experimental results have been difficult to interpret and use due to a large amount of apparent scatter: variation in the number of cycles to failure for a given cyclic stress or strain range. Recently Taylor (1998a, Journal...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(99)00112-8
更新日期：1999-11-01 00:00:00
abstract：:There are many diseases which cause detrimental changes in the trabecular structure of cancellous bone, leading to mechanical failure of the tissue. One approach to understanding the mechanisms of these diseases is to create idealized models that recreate the morphology of the tissue. This paper presents a partial dev...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(93)90057-l
更新日期：1993-08-01 00:00:00
abstract：:The purpose of this study was to determine the accuracy of a video system which our laboratory has been using to measure soft tissue strain. Both static and dynamic error analyses were performed to assess the accuracy of our video system. Static error was defined as the amount of movement reported by the video system ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(95)00131-x
更新日期：1996-06-01 00:00:00
abstract：:In biomechanical investigations, geometrically accurate computer models of anatomical structures can be created readily using computed-tomography scan images. However, representation of soft tissue structures is more challenging, relying on approximations to predict the muscle loading conditions that are essential in ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2010.05.037
更新日期：2010-10-19 00:00:00
abstract：:Linking human mechanical work to physiological work for the purpose of developing a model of physical fatigue is a complex problem that cannot be solved easily by conventional biomechanical analysis. The purpose of the study was to determine if two nonlinear analysis methods can address the fundamental issue of utiliz...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2009.06.011
更新日期：2009-09-18 00:00:00
abstract：:The thoracolumbar fascia (TLF) provides a means of attachment to the lumbar spine for several muscles including the transverse abdominis, and parts of the latissimus dorsi and internal oblique muscles. Previous biomechanical models of the lumbar spine either tend to omit the TLF on the assumption that its contribution...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2010.06.022
更新日期：2010-10-19 00:00:00
abstract：:Many cardiovascular diseases are characterised by the restriction of blood flow through arteries. Stents can be expanded within arteries to remove such restrictions; however, tissue in-growth into the stent can lead to restenosis. In order to predict the long-term efficacy of stenting, a mechanobiological model of the...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2012.12.014
更新日期：2013-03-15 00:00:00
abstract：:To establish whether conducting polymer-coated fabric sensors could be used to monitor breast motion, vertical breast motion of two large breasted women (C+ bra cup) was simultaneously monitored using an OPTOTRAK 3020 motion analysis system (200 Hz) and polymer-coated fabric sensors linked to a custom-made Bluetooth t...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2007.01.020
更新日期：2007-01-01 00:00:00
abstract：:The intervertebral disc is formed by the nucleus pulposus (NP) and annulus fibrosus (AF), and intervertebral tissue contains a large amount of negatively charged proteoglycan. When this tissue becomes deformed, a streaming potential is induced by liquid flow with positive ions. The anisotropic property of the AF tissu...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2011.06.018
更新日期：2011-09-02 00:00:00
abstract：:In this study, a new radiostereometric analysis (RSA) calibration cage was developed with the aim of improving the accuracy and precision of RSA. This development consisted of three steps: a numerical simulation technique was first used to design the new cage; a synthetic imaging method was then implemented to predict...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2007.11.012
更新日期：2008-01-01 00:00:00
abstract：:Low-back load during manual lifting is considered an important risk factor for the occurrence of low-back pain. Splitting a load, so it can be lifted beside the body (one load in each hand), instead of in front of the body, can be expected to reduce low-back load. Twelve healthy young men lifted 10 and 20-kg wide and ...
journal_title：Journal of biomechanics
pub_type： 临床试验,杂志文章
doi：10.1016/j.jbiomech.2008.10.013
更新日期：2009-01-05 00:00:00
abstract：:Mechanical constraints to spine motion can arise in a variety of real-world situations such as when shoulder belts prevent anterior translation of the thorax during automotive collisions. The effect of such constraint on spinal column-spinal cord interaction during injury remains unknown. The purpose of the present st...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2007.06.030
更新日期：2008-01-01 00:00:00
abstract：:Although numerous studies have addressed the effects of ACL injury and reconstruction on knee joint motion, there is currently little data available describing in vivo ACL strain during activities of daily living. Data describing in vivo ACL strain during activities such as gait is critical to understanding the biomec...
journal_title：Journal of biomechanics
pub_type： 临床试验,杂志文章
doi：10.1016/j.jbiomech.2012.10.031
更新日期：2013-02-01 00:00:00
abstract：:The differences between the assessments performed with and without the point cluster technique (PCT) for knee joint motions during the high-risk movements associated with non-contact anterior cruciate ligament (ACL) injuries have not been reported. This study aims to examine the differences between PCT and non-PCT ass...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2011.05.001
更新日期：2011-07-07 00:00:00
abstract：:In this work we propose a method to estimate the elastic properties of the extracellular matrix of articular cartilage, once the elastic properties of the chondrocytes and the whole tissue are known. The influence of the elastic properties of the tissue and the cell concentration on the estimated elastic properties of...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(03)00280-x
更新日期：2004-03-01 00:00:00
abstract：:Traumatic damage to the brainstem occurs frequently when the brain skull complex experiences injurious loading especially during those traumatic situations that produce diffuse axonal injury (DAI). DAI has been shown to be dependent on load direction and correlated with regional tissue deformation in response to rotat...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(98)00068-2
更新日期：1998-09-01 00:00:00
abstract：:The orientation of the line of pull and geometrical characteristics of rat semimembranosus lateralis muscle (SM1) were measured in a plane during isometric contractions at different muscle lengths. The orientation of the line of pull was always similar in our plane of analysis. It was always aligned with the external ...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(94)90051-5
更新日期：1994-09-01 00:00:00
abstract：:The problem of blood flow through stenoses is solved using the incompressible generalized Newtonian model. The Herschel-Bulkley, Bingham and power-law fluids are incorporated. The geometry corresponds to a rigid circular tube with a partial occlusion. Calculations are performed by a Galerkin finite-element method. For...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(95)00151-4
更新日期：1996-07-01 00:00:00
abstract：:Force plates for human movement analysis provide accurate measurements when mounted rigidly on an inertial reference frame. Large measurement errors occur, however, when the force plate is accelerated, or tilted relative to gravity. This prohibits the use of force plates in human perturbation studies with controlled s...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2018.05.009
更新日期：2018-06-25 00:00:00
abstract：:Bone is a dynamic tissue which, through the process of bone remodeling in the mature skeleton, renews itself during normal function and adapts to mechanical loads. It is, therefore, important to understand the effect of remodeling on the mechanical function of bone, as well as the effect of the inherent time lag in th...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/s0021-9290(00)00221-9
更新日期：2001-03-01 00:00:00
abstract：:The patchy distribution of atherosclerosis within arteries is widely attributed to local variation in haemodynamic wall shear stress (WSS). A recently-introduced metric, the transverse wall shear stress (transWSS), which is the average over the cardiac cycle of WSS components perpendicular to the temporal mean WSS vec...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/j.jbiomech.2016.11.035
更新日期：2017-01-04 00:00:00
abstract：:Cultured cells subjected to fluid flow are exposed to mechanical forces and electrokinetic forces. The convective current establishes an electrokinetic force created by the flow-dependent transport of mobile ions in the media over the charged cell surfaces. This current can be expressed as a current density, the curre...
journal_title：Journal of biomechanics
pub_type： 杂志文章
doi：10.1016/0021-9290(96)84535-0
更新日期：1996-11-01 00:00:00
