Abstract:
:The objective of this work is to compare the phenotypic and virulence genes characteristics in human and chicken isolates of Proteus mirabilis. The bacterial examination of 50 livers of individual broilers, marketed by four major outlets, revealed a high recovery of P. mirabilis (66%), and a low recovery frequency of Salmonella spp. (4%), Serratia odorifera (2%), Citrobacter brakii (2%), and Providencia stuartii (2%). The phenotypic biochemical characterization of the recovered 33 chicken isolates of P. mirabilis were compared to 30 human isolates (23 urinary and six respiratory isolates). The comparison revealed significant differences in the presence of gelatinase enzyme (100% presence in chicken isolates versus 91.3 and 83.3% presence in human urinary and respiratory isolates, respectively, P,0.05). The H(2)S production occurred in 100% of chicken isolates versus 95.6 and 66.7% presence in human urinary and respiratory isolates, respectively, P,0.05). The other 17 biochemical characteristics did not differ significantly among the three groups of isolates (P.0.05). Two virulence genes, the mrpA and FliL, were having a typical 100% presence in randomly selected isolates of P. mirabilis recovered from chicken livers (N510) versus isolates recovered from urinary (N55) and respiratory specimens of humans (N55) (P.0.05). The average percentage similarity of mrpA gene nucleotide sequence of poultry isolates to human urinary and respiratory isolates was 93.2 and 97.5-%, respectively. The high similarity in phenotypic characteristics, associated with typical frequency of presence of two virulence genes, and high similarity in sequences of mrpA gene among poultry versus human P. mirabilis isolates justifies future investigations targeting the evaluation of adaptable pathogenicity of avian Proteus mirabilis isolates to mammalian hosts.
journal_name
Pathog Glob Healthjournal_title
Pathogens and global healthauthors
Barbour EK,Hajj ZG,Hamadeh S,Shaib HA,Farran MT,Araj G,Faroon O,Barbour KE,Jirjis F,Azhar E,Kumosani T,Harakeh Sdoi
10.1179/2047773212Y.0000000042subject
Has Abstractpub_date
2012-10-01 00:00:00pages
352-7issue
6eissn
2047-7724issn
2047-7732journal_volume
106pub_type
杂志文章abstract:BACKGROUND:The prevalence of sickle cell disease (SCD) is extremely high in the Democratic Republic of Congo (DRC). Despite the high prevalence of this disease in our midst, there has been no report on the clinical features in the sickle cell pediatric population suffering from malaria in our midst. METHODS:A retrospe...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773213Y.0000000089
更新日期:2013-06-01 00:00:00
abstract::Neurocysticercosis has been recognized as a major cause of secondary epilepsy worldwide. So far, most of the knowledge about the disease comes from Latin America and the Indian subcontinent. Unfortunately, in sub-Saharan Africa the condition was neglected for a long time, mainly owing to the lack of appropriate diagn...
journal_title:Pathogens and global health
pub_type: 杂志文章,评审
doi:10.1179/2047773212Y.0000000047
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abstract::Genetic control strategies aimed to bias the sex of progenies towards males present a promising new paradigm to eliminate malaria-transmitting mosquitoes. A synthetic sex-ratio distortion (SD) system was successfully engineered in Anopheles gambiae by exploiting the meiotic activity of the I-PpoI endonuclease targetin...
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abstract:INTRODUCTION:Acute hepatitis A is a worldwide public health problem especially in developing countries. Recently, a large, community-wide outbreak of hepatitis A occurred in the northeast part of Thailand. METHODS:Demographic and clinical data as well as blood samples were collected and analyzed from patients with acu...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773213Y.0000000116
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abstract:BACKGROUND:Visceral leishmaniasis (VL), also known as kala-azar in the Indian sub-continent (ISC), is a major public health concern in Bangladesh, India, and Nepal, where it is caused by Leishmania donovani transmitted by the sand fly Phlebotomus argentipes. Various ecological parameters including air temperature, rain...
journal_title:Pathogens and global health
pub_type: 杂志文章,评审
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journal_title:Pathogens and global health
pub_type: 杂志文章,评审
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journal_title:Pathogens and global health
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abstract::The global spread of the 2019-nCoV is continuing and is fast moving, as indicated by the WHO raising the risk assessment to high. In this article, we provide a preliminary phylodynamic and phylogeographic analysis of this new virus. A Maximum Clade Credibility tree has been built using the 29 available whole genome se...
journal_title:Pathogens and global health
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journal_title:Pathogens and global health
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journal_title:Pathogens and global health
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abstract::Trichomonas vaginalis is a flagellated protozoan parasite that infects the human urogenital tract, causing the most common non-viral, sexually transmitted disease worldwide. In this study, genetic variants of T. vaginalis were identified in Henan Province, China. Fragments of the small subunit of nuclear ribosomal RNA...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773215Y.0000000020
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abstract:INTRODUCTION:Waste management through community mobilization to reduce breeding places at household level could be an effective and sustainable dengue vector control strategy in areas where vector breeding takes place in small discarded water containers. The objective of this study was to assess the validity of this a...
journal_title:Pathogens and global health
pub_type: 杂志文章,随机对照试验
doi:10.1179/2047773212Y.0000000060
更新日期:2012-12-01 00:00:00
abstract::Crimean-Congo hemorrhagic fever (CCHF) is endemic in Turkey, with peak incidence of hospital admissions in the summer months. The aim of this pilot study was to evaluate the role of the severity grading score (SGS) in predicting length of hospital stay, laboratory usage, need for blood products, and hence total costs ...
journal_title:Pathogens and global health
pub_type: 杂志文章
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更新日期:2016-01-01 00:00:00
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journal_title:Pathogens and global health
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journal_title:Pathogens and global health
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更新日期:2018-05-01 00:00:00
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journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773212Y.0000000069
更新日期:2013-01-01 00:00:00
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journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773213Y.0000000086
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journal_title:Pathogens and global health
pub_type: 杂志文章,评审
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journal_title:Pathogens and global health
pub_type: 杂志文章
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journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773213Y.0000000124
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journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1080/20477724.2021.1878442
更新日期:2021-01-24 00:00:00
abstract::Plasmodium vivax is now recognized as a cause of severe and fatal infection in many parts of the world. This prospective observational study was undertaken in a tertiary health setting to understand the spectrum of the disease burden and associated complications due to P. vivax malaria in central India. A malaria clin...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/204777213X13777615588180
更新日期:2013-09-01 00:00:00
abstract::Giardiasis, a common gastrointestinal parasitic infection in tropics, is diagnosed on stool microscopy (gold standard); however, its sensitivity is low due to intermittent fecal shedding. Coproantigen detection (ELISA) is useful but requires further evaluation. We aimed to study: (a) detection of Giardia by stool micr...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1080/20477724.2016.1254141
更新日期:2016-01-01 00:00:00
abstract::The aim of this study was to describe the clinical and epidemiological profile of immunosuppressed patients with imported strongyloidiasis in a non-endemic setting, and to compare these results with non-immunosuppressed patients. This is a case-control substudy from a larger observational retrospective study that incl...
journal_title:Pathogens and global health
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doi:10.1080/20477724.2020.1857491
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abstract::Recent data strongly suggest an association between the current outbreak of ZIKA virus (ZIKV) in many countries of Central and South America and a sharp increase in the detection of microcephaly and fetal malformations. The link with brain defect, which has been detected mainly in some areas of Brazil, is supported by...
journal_title:Pathogens and global health
pub_type: 杂志文章,评审
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更新日期:2016-01-01 00:00:00
abstract::Over 2 billion people in both developing as well as developed countries - over 30% of the world's population - are anaemic. With the classical preconception that oral iron administration or the intake of foods rich in iron increase haemoglobin concentration and reduce the prevalence of anaemia, specific programs have...
journal_title:Pathogens and global health
pub_type: 杂志文章,评审
doi:10.1179/2047773212Y.0000000043
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:Efforts to curb the spread of HIV transmission through transfusion of blood and its products is still a problem because of challenge in countries using antibody-based rapid methods to detect infection during window period. Transmission of HIV through infected blood and its products accounts for approximately...
journal_title:Pathogens and global health
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abstract::Bovine lactoferrin (bLf) is a multifunctional glycoprotein that plays an important role in innate immunity against infections, including influenza. Here we have dissected bLf into its C- and N-lobes and show that inhibition of influenza virus hemagglutination and cell infection is entirely attributable to the C-lobe ...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773212Y.0000000004
更新日期:2012-03-01 00:00:00
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journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773213Y.0000000111
更新日期:2013-09-01 00:00:00