Abstract:
BACKGROUND:Efforts to curb the spread of HIV transmission through transfusion of blood and its products is still a problem because of challenge in countries using antibody-based rapid methods to detect infection during window period. Transmission of HIV through infected blood and its products accounts for approximately 10% in African region. METHODS:This study analyzed true negativity of HIV infection in blood donors screened by ELISA test based on p24 core antigen detection. Four hundred and eighty (480) blood donors initially negative for HIV antibody by rapid screening kit, Determine™ HIV-1/2 (Abbott Laboratory, IL, USA) and re-screened with Immuno Comb® II HIV 1 and 2 (Bispot kit PBS Organics and Israel 2005). The samples were further tested for the presence of HIV antibody and p24 HIV core antigen using ELISA kits (Genscreen TM ULTRA HIV Ag-Ab) following manufacturer's instructions. All donors initially tested negative for Hepatitis B virus, Hepatitis C virus. RESULT:Two (0.42%) of 480 blood donors tested positive for the p24 HIV core antigen. The two positive donors for the p24 antigen had multiple sexual partners and recent sexually transmitted infections. CONCLUSION:The association of the HIV p24 antigen with blood donation was highly significant (p = 0.000) and pose a great risk to recipients if screening of blood donor is only carried out by HIV antibody detection.
journal_name
Pathog Glob Healthjournal_title
Pathogens and global healthauthors
Olowe OA,Mabayoje VO,Akanbi O,Adefioye OJ,Olowe RA,Fadeni EK,Oluremi AS,Opaleye OOdoi
10.1080/20477724.2016.1205311subject
Has Abstractpub_date
2016-06-01 00:00:00pages
205-8issue
4-5eissn
2047-7724issn
2047-7732journal_volume
110pub_type
杂志文章abstract::The global spread of the 2019-nCoV is continuing and is fast moving, as indicated by the WHO raising the risk assessment to high. In this article, we provide a preliminary phylodynamic and phylogeographic analysis of this new virus. A Maximum Clade Credibility tree has been built using the 29 available whole genome se...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1080/20477724.2020.1725339
更新日期:2020-03-01 00:00:00
abstract::Carbapenem-resistant Klebsiella pneumoniae (CRKP) has been known as a nosocomial pathogen, both for the last 10 years in Turkey and for 20 years worldwide. Due to limited treatment options and high mortality rates, despite improvements in the field of medicine at the present time, CRKP is still a big threat for public...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1080/20477724.2016.1254976
更新日期:2016-01-01 00:00:00
abstract::The objective of this work is to compare the phenotypic and virulence genes characteristics in human and chicken isolates of Proteus mirabilis. The bacterial examination of 50 livers of individual broilers, marketed by four major outlets, revealed a high recovery of P. mirabilis (66%), and a low recovery frequency of ...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773212Y.0000000042
更新日期:2012-10-01 00:00:00
abstract::Crimean-Congo hemorrhagic fever (CCHF) is endemic in Turkey, with peak incidence of hospital admissions in the summer months. The aim of this pilot study was to evaluate the role of the severity grading score (SGS) in predicting length of hospital stay, laboratory usage, need for blood products, and hence total costs ...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1080/20477724.2015.1136130
更新日期:2016-01-01 00:00:00
abstract::During the last decade, the chikungunya (CHIKV) virus has expanded its range of activity, conquering new territories and becoming an important global health threat. In particular, the challenge represented by the recent emergence of CHIKV in the Americas has strengthened the need of a safe and effective vaccine. Altho...
journal_title:Pathogens and global health
pub_type: 杂志文章,评审
doi:10.1179/2047773215Y.0000000017
更新日期:2015-06-01 00:00:00
abstract::Sand flies of Phlebotomus papatasi and P. sergenti are the main vectors of cutaneous leishmanisis (CL) in the old world. We aimed to screen Iranian P. papatasi and P. sergenti for their natural infections with Wolbachia and to determine their phylogenetic association with other species. Wolbachia surface protein (wsp)...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1080/20477724.2018.1471438
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:Visceral leishmaniasis (VL), also known as kala-azar in the Indian sub-continent (ISC), is a major public health concern in Bangladesh, India, and Nepal, where it is caused by Leishmania donovani transmitted by the sand fly Phlebotomus argentipes. Various ecological parameters including air temperature, rain...
journal_title:Pathogens and global health
pub_type: 杂志文章,评审
doi:10.1080/20477724.2016.1180775
更新日期:2016-05-01 00:00:00
abstract::Plasma levels of pro- and anti-inflammatory cytokines of Plasmodium falciparum-infected patients with severe malaria (SM; n = 62) and uncomplicated malaria (UM; n = 69) from Sri Lanka were assessed. SM patients had significantly higher levels of TNF-alpha (P < 0·01), IL-6 (P < 0·01), and IL-10 (P < 0·05) compared to t...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773212Y.0000000069
更新日期:2013-01-01 00:00:00
abstract::One of the essential steps in targeting tuberculosis (TB) intervention is early diagnosis and treatment of patients by reducing the reservoir of infection in the community. In the North-Eastern (NE) region of India pulmonary TB and paragonimiasis are overlapping public health issues. We performed a cross-sectional stu...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773213Y.0000000086
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:We aimed to identify challenges and to propose solutions for the implementation of tuberculosis (TB) programmes in rural Sub-Saharan Africa (SSA) by evaluating the outcomes of the TB programme in the Ancuabe district in rural Northern Mozambique. METHODS:Retrospective descriptive study of the patients inclu...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773215Y.0000000027
更新日期:2015-07-01 00:00:00
abstract::The study describes prevalence, clinical symptoms and risk factors for brucellosis in personnel engaged in veterinary health care in Karnataka, India. A total of 1050 sera samples were collected from animal handlers, veterinarians, veterinary students, para-veterinarians and persons engaged in artificial insemination ...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1080/20477724.2017.1345366
更新日期:2017-07-01 00:00:00
abstract::Trichomonas vaginalis is a flagellated protozoan parasite that infects the human urogenital tract, causing the most common non-viral, sexually transmitted disease worldwide. In this study, genetic variants of T. vaginalis were identified in Henan Province, China. Fragments of the small subunit of nuclear ribosomal RNA...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773215Y.0000000020
更新日期:2015-07-01 00:00:00
abstract::Italy was initially one of the worse affected countries by the novel coronavirus (COVID-19). Medical students frequenting hospitals are more susceptible to be infected by the virus but also able to see the effects of the pandemic from the frontline. The aim of this study was to assess the COVID-19 related knowledge, b...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1080/20477724.2021.1878447
更新日期:2021-01-31 00:00:00
abstract::Over 2 billion people in both developing as well as developed countries - over 30% of the world's population - are anaemic. With the classical preconception that oral iron administration or the intake of foods rich in iron increase haemoglobin concentration and reduce the prevalence of anaemia, specific programs have...
journal_title:Pathogens and global health
pub_type: 杂志文章,评审
doi:10.1179/2047773212Y.0000000043
更新日期:2012-08-01 00:00:00
abstract::Eastern Europe (EE) has been severely affected by mosquito-borne viruses (moboviruses). In this review, we summarize the epidemiology of moboviruses, with particular attention to West Nile virus (WNV). The study of WNV human cases in EE between 2010 and 2016, revealed that the epidemiology of WNV in EE is complex with...
journal_title:Pathogens and global health
pub_type: 杂志文章,评审
doi:10.1080/20477724.2018.1483567
更新日期:2018-07-01 00:00:00
abstract::Genetic control strategies aimed to bias the sex of progenies towards males present a promising new paradigm to eliminate malaria-transmitting mosquitoes. A synthetic sex-ratio distortion (SD) system was successfully engineered in Anopheles gambiae by exploiting the meiotic activity of the I-PpoI endonuclease targetin...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1080/20477724.2020.1803628
更新日期:2020-10-01 00:00:00
abstract::Giardiasis is one of the commonest intestinal parasitic infections in Cuba. In order to determine care-seeking behaviour and diagnostic processes in paediatric in-patients with giardiasis, structured questionnaires were administered by interview mothers of children with giardiasis during January to December 2010. Duri...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773214Y.0000000152
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND:The prevalence of sickle cell disease (SCD) is extremely high in the Democratic Republic of Congo (DRC). Despite the high prevalence of this disease in our midst, there has been no report on the clinical features in the sickle cell pediatric population suffering from malaria in our midst. METHODS:A retrospe...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773213Y.0000000089
更新日期:2013-06-01 00:00:00
abstract::The second largest outbreak of Ebolavirus is currently ongoing in Eastern Democratic Republic of the Congo (DRC) and is characterized by lack of compliance with recommended control measures. Trusted local health agents, including medical students, may be valuable social mobilizers in this challenging context. We repor...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1080/20477724.2020.1754654
更新日期:2020-05-18 00:00:00
abstract::Approximately 120 years ago the link between mosquito and the malaria transmission was discovered. However, even today it remains an open question whether the parasite is able to direct the blood-seeking and feeding behavior of its mosquito vector to maximize the probability of transmission. If the parasite has this a...
journal_title:Pathogens and global health
pub_type: 杂志文章,评审
doi:10.1080/20477724.2019.1703398
更新日期:2019-12-01 00:00:00
abstract:INTRODUCTION:Waste management through community mobilization to reduce breeding places at household level could be an effective and sustainable dengue vector control strategy in areas where vector breeding takes place in small discarded water containers. The objective of this study was to assess the validity of this a...
journal_title:Pathogens and global health
pub_type: 杂志文章,随机对照试验
doi:10.1179/2047773212Y.0000000060
更新日期:2012-12-01 00:00:00
abstract::We previously attempted to identify 96 nonpolio enteroviruses (EVs) recovered in RD cell culture from children <15 years with acute flaccid paralysis in Nigeria. We succeeded in identifying 69 of the isolates. Here, we describe an attempt to identify the remaining 27 isolates. Twenty-six (the 27th isolate was exhauste...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1080/20477724.2018.1548117
更新日期:2018-12-01 00:00:00
abstract::Infection caused by intestinal parasites has significant public health consequences amongst children in the developing world. Street children are an under-studied group of society subjected to increased health risks when compared to their peers. To estimate the prevalence of intestinal parasitic infection and ascertai...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773213Y.0000000073
更新日期:2013-03-01 00:00:00
abstract::Methicillin-resistant Staphylococcus aureus (MRSA) is one of the important pathogens worldwide showing resistance to several widely used antibiotics. This has made the treatment of MRSA infections harder, especially due to their prevalence in the hospital setting. We evaluated the antibiotic susceptibility patterns of...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1080/20477724.2020.1827197
更新日期:2020-12-01 00:00:00
abstract::Giardiasis, a common gastrointestinal parasitic infection in tropics, is diagnosed on stool microscopy (gold standard); however, its sensitivity is low due to intermittent fecal shedding. Coproantigen detection (ELISA) is useful but requires further evaluation. We aimed to study: (a) detection of Giardia by stool micr...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1080/20477724.2016.1254141
更新日期:2016-01-01 00:00:00
abstract::Neurocysticercosis has been recognized as a major cause of secondary epilepsy worldwide. So far, most of the knowledge about the disease comes from Latin America and the Indian subcontinent. Unfortunately, in sub-Saharan Africa the condition was neglected for a long time, mainly owing to the lack of appropriate diagn...
journal_title:Pathogens and global health
pub_type: 杂志文章,评审
doi:10.1179/2047773212Y.0000000047
更新日期:2012-09-01 00:00:00
abstract::Acanthamoeba keratitis is a painful and progressive infection of the cornea that can result in loss of vision. Here, for the first time in Pakistan, we report two cases of Acanthamoeba keratitis. The first patient was a 37-year-old female who presented with severe itching, redness, pain, along with loss of vision. The...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773213Y.0000000124
更新日期:2014-01-01 00:00:00
abstract::Bovine lactoferrin (bLf) is a multifunctional glycoprotein that plays an important role in innate immunity against infections, including influenza. Here we have dissected bLf into its C- and N-lobes and show that inhibition of influenza virus hemagglutination and cell infection is entirely attributable to the C-lobe ...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773212Y.0000000004
更新日期:2012-03-01 00:00:00
abstract::Plasmodium vivax is now recognized as a cause of severe and fatal infection in many parts of the world. This prospective observational study was undertaken in a tertiary health setting to understand the spectrum of the disease burden and associated complications due to P. vivax malaria in central India. A malaria clin...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/204777213X13777615588180
更新日期:2013-09-01 00:00:00
abstract::The aim of this study was to describe the clinical and epidemiological profile of immunosuppressed patients with imported strongyloidiasis in a non-endemic setting, and to compare these results with non-immunosuppressed patients. This is a case-control substudy from a larger observational retrospective study that incl...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1080/20477724.2020.1857491
更新日期:2020-12-30 00:00:00