The global spread of 2019-nCoV: a molecular evolutionary analysis.


:The global spread of the 2019-nCoV is continuing and is fast moving, as indicated by the WHO raising the risk assessment to high. In this article, we provide a preliminary phylodynamic and phylogeographic analysis of this new virus. A Maximum Clade Credibility tree has been built using the 29 available whole genome sequences of 2019-nCoV and two whole genome sequences that are highly similar sequences from Bat SARS-like Coronavirus available in GeneBank. We are able to clarify the mechanism of transmission among the countries which have provided the 2019-nCoV sequence isolates from their patients. The Bayesian phylogeographic reconstruction shows that the 2019-2020 nCoV most probably originated from the Bat SARS-like Coronavirus circulating in the Rhinolophus bat family. In agreement with epidemiological observations, the most likely geographic origin of the new outbreak was the city of Wuhan, China, where 2019-nCoV time of the most recent common ancestor emerged, according to molecular clock analysis, around November 25th, 2019. These results, together with previously recorded epidemics, suggest a recurring pattern of periodical epizootic outbreaks due to Betacoronavirus. Moreover, our study describes the same population genetic dynamic underlying the SARS 2003 epidemic, and suggests the urgent need for the development of effective molecular surveillance strategies of Betacoronavirus among animals and Rhinolophus of the bat family.


Pathog Glob Health


Benvenuto D,Giovanetti M,Salemi M,Prosperi M,De Flora C,Junior Alcantara LC,Angeletti S,Ciccozzi M




Has Abstract


2020-03-01 00:00:00












  • Identification of previously untypable RD cell line isolates and detection of EV-A71 genotype C1 in a child with AFP in Nigeria.

    abstract::We previously attempted to identify 96 nonpolio enteroviruses (EVs) recovered in RD cell culture from children <15 years with acute flaccid paralysis in Nigeria. We succeeded in identifying 69 of the isolates. Here, we describe an attempt to identify the remaining 27 isolates. Twenty-six (the 27th isolate was exhauste...

    journal_title:Pathogens and global health

    pub_type: 杂志文章


    authors: Adewumi OM,Faleye TOC,Okeowo CO,Oladapo AM,Oyathelemhi J,Olaniyi OA,Isola OC,Adeniji JA

    更新日期:2018-12-01 00:00:00

  • Comparison of phenotypic and virulence genes characteristics in human and chicken isolates of Proteus mirabilis.

    abstract::The objective of this work is to compare the phenotypic and virulence genes characteristics in human and chicken isolates of Proteus mirabilis. The bacterial examination of 50 livers of individual broilers, marketed by four major outlets, revealed a high recovery of P. mirabilis (66%), and a low recovery frequency of ...

    journal_title:Pathogens and global health

    pub_type: 杂志文章


    authors: Barbour EK,Hajj ZG,Hamadeh S,Shaib HA,Farran MT,Araj G,Faroon O,Barbour KE,Jirjis F,Azhar E,Kumosani T,Harakeh S

    更新日期:2012-10-01 00:00:00

  • Clinical and molecular monitoring of Plasmodium falciparum resistance to antimalarial drug (artesunate+sulphadoxine-pyrimethamine) in two highly malarious district of Madhya Pradesh, Central India from 2012-2014.

    abstract::The spread of P. falciparum resistant strain has led to a significant resurgence of malaria morbidity and mortality. The current cornerstone in malaria treatment in India is Artemisinin based Combination (Artesunate + Sulphadoxine-Pyrimethamine) Therapy (ACT) for treatment of uncomplicated P. falciparum malaria since ...

    journal_title:Pathogens and global health

    pub_type: 杂志文章


    authors: Mishra S,Bharti PK,Shukla MM,Ali NA,Kashyotia SS,Kumar A,Dhariwal AC,Singh N

    更新日期:2017-06-01 00:00:00

  • Frequency, diagnostic performance of coproantigen detection and genotyping of the Giardia among patients referred to a multi-level teaching hospital in northern India.

    abstract::Giardiasis, a common gastrointestinal parasitic infection in tropics, is diagnosed on stool microscopy (gold standard); however, its sensitivity is low due to intermittent fecal shedding. Coproantigen detection (ELISA) is useful but requires further evaluation. We aimed to study: (a) detection of Giardia by stool micr...

    journal_title:Pathogens and global health

    pub_type: 杂志文章


    authors: Ghoshal U,Shukla R,Pant P,Ghoshal UC

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  • Factors associated with parasitic infection amongst street children in orphanages across Lima, Peru.

    abstract::Infection caused by intestinal parasites has significant public health consequences amongst children in the developing world. Street children are an under-studied group of society subjected to increased health risks when compared to their peers. To estimate the prevalence of intestinal parasitic infection and ascertai...

    journal_title:Pathogens and global health

    pub_type: 杂志文章


    authors: Bailey C,Lopez S,Camero A,Taiquiri C,Arhuay Y,Moore DA

    更新日期:2013-03-01 00:00:00

  • Failure of chemotherapy in the first reported cases of Acanthamoeba keratitis in Pakistan.

    abstract::Acanthamoeba keratitis is a painful and progressive infection of the cornea that can result in loss of vision. Here, for the first time in Pakistan, we report two cases of Acanthamoeba keratitis. The first patient was a 37-year-old female who presented with severe itching, redness, pain, along with loss of vision. The...

    journal_title:Pathogens and global health

    pub_type: 杂志文章


    authors: Siddiqui R,Chaudhry T,Lakhundi S,Ahmad K,Khan NA

    更新日期:2014-01-01 00:00:00

  • Evaluation of Syrian refugees' emergency service admissions in the western region of Turkey.

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    journal_title:Pathogens and global health

    pub_type: 杂志文章


    authors: Kaya H,Sengoren Dikis O,Sezgin B,Demirci H,Haberal MA,Akar E,Yüksel M

    更新日期:2021-01-24 00:00:00

  • Ebola crisis in Eastern Democratic Republic of Congo: student-led community engagement.

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    journal_title:Pathogens and global health

    pub_type: 杂志文章


    authors: Masumbuko Claude K,Hawkes MT

    更新日期:2020-05-18 00:00:00

  • West Nile virus and other mosquito-borne viruses present in Eastern Europe.

    abstract::Eastern Europe (EE) has been severely affected by mosquito-borne viruses (moboviruses). In this review, we summarize the epidemiology of moboviruses, with particular attention to West Nile virus (WNV). The study of WNV human cases in EE between 2010 and 2016, revealed that the epidemiology of WNV in EE is complex with...

    journal_title:Pathogens and global health

    pub_type: 杂志文章,评审


    authors: Napp S,Petrić D,Busquets N

    更新日期:2018-07-01 00:00:00

  • Cystic echinococcosis in Mundari tribe-members of South Sudan.

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    journal_title:Pathogens and global health

    pub_type: 杂志文章


    authors: Stewart BT,Jacob J,Finn T,Lado M,Napoleon R,Brooker S,Sidhu PS,Kolaczinski J

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    journal_title:Pathogens and global health

    pub_type: 杂志文章


    authors: James BO,Agbonile IO,Okolo M,Lawani AO,Omoaregba JO

    更新日期:2013-06-01 00:00:00

  • Active detection of tuberculosis and paragonimiasis in the remote areas in North-Eastern India using cough as a simple indicator.

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    journal_title:Pathogens and global health

    pub_type: 杂志文章


    authors: Rekha Devi K,Narain K,Mahanta J,Deori R,Lego K,Goswami D,Kumar Rajguru S,Agatsuma T

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    journal_title:Pathogens and global health

    pub_type: 杂志文章


    authors: Haghighat-Khah RE,Sharma A,Wunderlich MR,Morselli G,Marston LA,Bamikole C,Hall A,Kranjc N,Taxiarchi C,Sharakhov I,Galizi R

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    pub_type: 杂志文章


    authors: Karimian F,Vatandoost H,Rassi Y,Maleki-Ravasan N,Choubdar N,Koosha M,Arzamani K,Moradi-Asl E,Veysi A,Alipour H,Shirani M,Oshaghi MA

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    journal_title:Pathogens and global health

    pub_type: 杂志文章


    authors: Bozkurt I,Sunbul M,Yilmaz H,Esen S,Leblebicioglu H,Beeching NJ

    更新日期:2016-01-01 00:00:00

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    authors: Escobedo AA,Almirall P,Ávila I,Salazar Y,Alfonso M

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    journal_title:Pathogens and global health

    pub_type: 杂志文章


    authors: Jain V,Agrawal A,Singh N

    更新日期:2013-09-01 00:00:00

  • Community mobilization and household level waste management for dengue vector control in Gampaha district of Sri Lanka; an intervention study.

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    journal_title:Pathogens and global health

    pub_type: 杂志文章,随机对照试验


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    journal_title:Pathogens and global health

    pub_type: 杂志文章


    authors: Ammendolia MG,Agamennone M,Pietrantoni A,Lannutti F,Siciliano RA,De Giulio B,Amici C,Superti F

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    journal_title:Pathogens and global health

    pub_type: 杂志文章


    authors: Siriez JY,Lupoglazoff JM,Bouchy-Bagros ML,Pull L,Denjoy I

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  • Neurocysticercosis in sub-Saharan Africa: a review of prevalence, clinical characteristics, diagnosis, and management.

    abstract::Neurocysticercosis has been recognized as a major cause of secondary epilepsy worldwide. So far, most of the knowledge about the disease comes from Latin America and the Indian subcontinent. Unfortunately, in sub-Saharan Africa the condition was neglected for a long time, mainly owing to the lack of appropriate diagn...

    journal_title:Pathogens and global health

    pub_type: 杂志文章,评审


    authors: Winkler AS

    更新日期:2012-09-01 00:00:00

  • Implication of vector characteristics of Phlebotomus argentipes in the kala-azar elimination programme in the Indian sub-continent.

    abstract:BACKGROUND:Visceral leishmaniasis (VL), also known as kala-azar in the Indian sub-continent (ISC), is a major public health concern in Bangladesh, India, and Nepal, where it is caused by Leishmania donovani transmitted by the sand fly Phlebotomus argentipes. Various ecological parameters including air temperature, rain...

    journal_title:Pathogens and global health

    pub_type: 杂志文章,评审


    authors: Chowdhury R,Kumar V,Mondal D,Das ML,Das P,Dash AP,Kroeger A

    更新日期:2016-05-01 00:00:00

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    journal_title:Pathogens and global health

    pub_type: 杂志文章,评审


    authors: Sharma D,Choudhary M,Shastri S,Sharma PK

    更新日期:2015-03-01 00:00:00

  • Humans parasitized by the hard tick Ixodes ricinus are seropositive to Midichloria mitochondrii: is Midichloria a novel pathogen, or just a marker of tick bite?

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    journal_title:Pathogens and global health

    pub_type: 杂志文章


    authors: Mariconti M,Epis S,Gaibani P,Dalla Valle C,Sassera D,Tomao P,Fabbi M,Castelli F,Marone P,Sambri V,Bazzocchi C,Bandi C

    更新日期:2012-11-01 00:00:00

  • Malaria, clinical features and acute crisis in children suffering from sickle cell disease in resource-limited settings: a retrospective description of 90 cases.

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    journal_title:Pathogens and global health

    pub_type: 杂志文章


    authors: Aloni MN,Tshimanga BK,Ekulu PM,Ehungu JL,Ngiyulu RM

    更新日期:2013-06-01 00:00:00

  • Discovery and characterization of two Nimrod superfamily members in Anopheles gambiae.

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    journal_title:Pathogens and global health

    pub_type: 杂志文章


    authors: Midega J,Blight J,Lombardo F,Povelones M,Kafatos F,Christophides GK

    更新日期:2013-12-01 00:00:00

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    journal_title:Pathogens and global health

    pub_type: 杂志文章,评审


    authors: Emami SN,Hajkazemian M,Mozūraitis R

    更新日期:2019-12-01 00:00:00

  • Do we need a vaccine against chikungunya?

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    journal_title:Pathogens and global health

    pub_type: 杂志文章,评审


    authors: Rezza G

    更新日期:2015-06-01 00:00:00

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    journal_title:Pathogens and global health

    pub_type: 杂志文章


    authors: Olowe OA,Mabayoje VO,Akanbi O,Adefioye OJ,Olowe RA,Fadeni EK,Oluremi AS,Opaleye OO

    更新日期:2016-06-01 00:00:00

  • Prevalence and risk factors of brucellosis among veterinary health care professionals.

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    journal_title:Pathogens and global health

    pub_type: 杂志文章


    authors: Shome R,Kalleshamurthy T,Shankaranarayana PB,Giribattanvar P,Chandrashekar N,Mohandoss N,Shome BR,Kumar A,Barbuddhe SB,Rahman H

    更新日期:2017-07-01 00:00:00