Abstract:
:Recent data strongly suggest an association between the current outbreak of ZIKA virus (ZIKV) in many countries of Central and South America and a sharp increase in the detection of microcephaly and fetal malformations. The link with brain defect, which has been detected mainly in some areas of Brazil, is supported by the following evidence: (1) ZIKV transmission from infected pregnant women to their fetuses; (2) the potential of ZIKV to determine a specific congenital fetal syndrome characterized by abnormalities involving primarily the developing brain and eye. In particular, the risk of transmission and congenital disease appears to be restricted to mother's infection during the first trimester of pregnancy. Among brain defects, microcephaly, brain calcifications, and ventriculomegaly are the most frequent abnormalities of the central nervous system detected so far. However, relevant information on effect of maternal infection with ZIKV on the fetus is still limited. In this review, we focus our attention on current knowledge about ZIKV infection in pregnancy, discussing relevant issues and open problems which merit further investigation.
journal_name
Pathog Glob Healthjournal_title
Pathogens and global healthauthors
Ticconi C,Pietropolli A,Rezza Gdoi
10.1080/20477724.2016.1234804subject
Has Abstractpub_date
2016-01-01 00:00:00pages
262-268issue
7-8eissn
2047-7724issn
2047-7732journal_volume
110pub_type
杂志文章,评审abstract:BACKGROUND:While the aetiology for most psychotic disorders is unknown, a strong association has been observed between Toxoplasma gondii infection and psychosis. The proportion of individuals with psychotic disorders who have current or past infection with toxoplasma has been varied. Reports from the African continent ...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773213Y.0000000093
更新日期:2013-06-01 00:00:00
abstract::The second largest outbreak of Ebolavirus is currently ongoing in Eastern Democratic Republic of the Congo (DRC) and is characterized by lack of compliance with recommended control measures. Trusted local health agents, including medical students, may be valuable social mobilizers in this challenging context. We repor...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1080/20477724.2020.1754654
更新日期:2020-05-18 00:00:00
abstract::Midichloria mitochondrii is an intracellular bacterium found in the hard tick Ixodes ricinus. In this arthropod, M. mitochondrii is observed in the oocytes and in other cells of the ovary, where the symbiont is present in the cell cytoplasm and inside the mitochondria. No studies have so far investigated whether M. m...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773212Y.0000000050
更新日期:2012-11-01 00:00:00
abstract::Over 2 billion people in both developing as well as developed countries - over 30% of the world's population - are anaemic. With the classical preconception that oral iron administration or the intake of foods rich in iron increase haemoglobin concentration and reduce the prevalence of anaemia, specific programs have...
journal_title:Pathogens and global health
pub_type: 杂志文章,评审
doi:10.1179/2047773212Y.0000000043
更新日期:2012-08-01 00:00:00
abstract::Immigration increases physical, mental, and social health problems. Emergency departments constitute resources that refugees can easily access and where they frequently present. Physicians from every specialty (chest diseases, thoracic surgery, internal diseases, etc.) may be consulted if needed. We aimed to compare d...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1080/20477724.2021.1878442
更新日期:2021-01-24 00:00:00
abstract::Plasmodium vivax is now recognized as a cause of severe and fatal infection in many parts of the world. This prospective observational study was undertaken in a tertiary health setting to understand the spectrum of the disease burden and associated complications due to P. vivax malaria in central India. A malaria clin...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/204777213X13777615588180
更新日期:2013-09-01 00:00:00
abstract::The global spread of the 2019-nCoV is continuing and is fast moving, as indicated by the WHO raising the risk assessment to high. In this article, we provide a preliminary phylodynamic and phylogeographic analysis of this new virus. A Maximum Clade Credibility tree has been built using the 29 available whole genome se...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1080/20477724.2020.1725339
更新日期:2020-03-01 00:00:00
abstract::Bovine lactoferrin (bLf) is a multifunctional glycoprotein that plays an important role in innate immunity against infections, including influenza. Here we have dissected bLf into its C- and N-lobes and show that inhibition of influenza virus hemagglutination and cell infection is entirely attributable to the C-lobe ...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773212Y.0000000004
更新日期:2012-03-01 00:00:00
abstract::Genetic control strategies aimed to bias the sex of progenies towards males present a promising new paradigm to eliminate malaria-transmitting mosquitoes. A synthetic sex-ratio distortion (SD) system was successfully engineered in Anopheles gambiae by exploiting the meiotic activity of the I-PpoI endonuclease targetin...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1080/20477724.2020.1803628
更新日期:2020-10-01 00:00:00
abstract::One of the essential steps in targeting tuberculosis (TB) intervention is early diagnosis and treatment of patients by reducing the reservoir of infection in the community. In the North-Eastern (NE) region of India pulmonary TB and paragonimiasis are overlapping public health issues. We performed a cross-sectional stu...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773213Y.0000000086
更新日期:2013-04-01 00:00:00
abstract::The objective of this work is to compare the phenotypic and virulence genes characteristics in human and chicken isolates of Proteus mirabilis. The bacterial examination of 50 livers of individual broilers, marketed by four major outlets, revealed a high recovery of P. mirabilis (66%), and a low recovery frequency of ...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773212Y.0000000042
更新日期:2012-10-01 00:00:00
abstract::We previously attempted to identify 96 nonpolio enteroviruses (EVs) recovered in RD cell culture from children <15 years with acute flaccid paralysis in Nigeria. We succeeded in identifying 69 of the isolates. Here, we describe an attempt to identify the remaining 27 isolates. Twenty-six (the 27th isolate was exhauste...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1080/20477724.2018.1548117
更新日期:2018-12-01 00:00:00
abstract::Giardiasis is one of the commonest intestinal parasitic infections in Cuba. In order to determine care-seeking behaviour and diagnostic processes in paediatric in-patients with giardiasis, structured questionnaires were administered by interview mothers of children with giardiasis during January to December 2010. Duri...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773214Y.0000000152
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND:Visceral leishmaniasis (VL), also known as kala-azar in the Indian sub-continent (ISC), is a major public health concern in Bangladesh, India, and Nepal, where it is caused by Leishmania donovani transmitted by the sand fly Phlebotomus argentipes. Various ecological parameters including air temperature, rain...
journal_title:Pathogens and global health
pub_type: 杂志文章,评审
doi:10.1080/20477724.2016.1180775
更新日期:2016-05-01 00:00:00
abstract::The spread of P. falciparum resistant strain has led to a significant resurgence of malaria morbidity and mortality. The current cornerstone in malaria treatment in India is Artemisinin based Combination (Artesunate + Sulphadoxine-Pyrimethamine) Therapy (ACT) for treatment of uncomplicated P. falciparum malaria since ...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1080/20477724.2017.1331875
更新日期:2017-06-01 00:00:00
abstract::The aim of this study was to describe the clinical and epidemiological profile of immunosuppressed patients with imported strongyloidiasis in a non-endemic setting, and to compare these results with non-immunosuppressed patients. This is a case-control substudy from a larger observational retrospective study that incl...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1080/20477724.2020.1857491
更新日期:2020-12-30 00:00:00
abstract::In order to assess cardiac tolerance of halofantrine in children, we studied, retrospectively, 15 non complicated falciparum malaria cases treated with halofantrine, and focused on the effect on ventricular repolarisation. Our data showed that halofantrine can produce a moderate QTc prolongation without any life-thre...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773212Y.0000000007
更新日期:2012-05-01 00:00:00
abstract::Giardiasis, a common gastrointestinal parasitic infection in tropics, is diagnosed on stool microscopy (gold standard); however, its sensitivity is low due to intermittent fecal shedding. Coproantigen detection (ELISA) is useful but requires further evaluation. We aimed to study: (a) detection of Giardia by stool micr...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1080/20477724.2016.1254141
更新日期:2016-01-01 00:00:00
abstract::During the last decade, the chikungunya (CHIKV) virus has expanded its range of activity, conquering new territories and becoming an important global health threat. In particular, the challenge represented by the recent emergence of CHIKV in the Americas has strengthened the need of a safe and effective vaccine. Altho...
journal_title:Pathogens and global health
pub_type: 杂志文章,评审
doi:10.1179/2047773215Y.0000000017
更新日期:2015-06-01 00:00:00
abstract::Neonatal liver abscess is an uncommon seen condition in neonatology and it holds a very high neonatal mortality because of difficulty in diagnosis and treatment. Till today, only few instances are reported that too are mainly in preterm. Its diagnosis requires a high index of suspicion. Fungal hepatic abscess is very ...
journal_title:Pathogens and global health
pub_type: 杂志文章,评审
doi:10.1179/2047773215Y.0000000008
更新日期:2015-03-01 00:00:00
abstract::Infection caused by intestinal parasites has significant public health consequences amongst children in the developing world. Street children are an under-studied group of society subjected to increased health risks when compared to their peers. To estimate the prevalence of intestinal parasitic infection and ascertai...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773213Y.0000000073
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:The prevalence of sickle cell disease (SCD) is extremely high in the Democratic Republic of Congo (DRC). Despite the high prevalence of this disease in our midst, there has been no report on the clinical features in the sickle cell pediatric population suffering from malaria in our midst. METHODS:A retrospe...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773213Y.0000000089
更新日期:2013-06-01 00:00:00
abstract::Acanthamoeba keratitis is a painful and progressive infection of the cornea that can result in loss of vision. Here, for the first time in Pakistan, we report two cases of Acanthamoeba keratitis. The first patient was a 37-year-old female who presented with severe itching, redness, pain, along with loss of vision. The...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773213Y.0000000124
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:We aimed to identify challenges and to propose solutions for the implementation of tuberculosis (TB) programmes in rural Sub-Saharan Africa (SSA) by evaluating the outcomes of the TB programme in the Ancuabe district in rural Northern Mozambique. METHODS:Retrospective descriptive study of the patients inclu...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773215Y.0000000027
更新日期:2015-07-01 00:00:00
abstract::Eastern Europe (EE) has been severely affected by mosquito-borne viruses (moboviruses). In this review, we summarize the epidemiology of moboviruses, with particular attention to West Nile virus (WNV). The study of WNV human cases in EE between 2010 and 2016, revealed that the epidemiology of WNV in EE is complex with...
journal_title:Pathogens and global health
pub_type: 杂志文章,评审
doi:10.1080/20477724.2018.1483567
更新日期:2018-07-01 00:00:00
abstract::Approximately 120 years ago the link between mosquito and the malaria transmission was discovered. However, even today it remains an open question whether the parasite is able to direct the blood-seeking and feeding behavior of its mosquito vector to maximize the probability of transmission. If the parasite has this a...
journal_title:Pathogens and global health
pub_type: 杂志文章,评审
doi:10.1080/20477724.2019.1703398
更新日期:2019-12-01 00:00:00
abstract::Anti-bacterial proteins in mosquitoes are known to play an important modulatory role on immune responses to infections with human pathogens including malaria parasites. In this study we characterized two members of the Anopheles gambiae Nimrod superfamily, namely AgNimB2 and AgEater. We confirm that current annotation...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/204777213X13867543472674
更新日期:2013-12-01 00:00:00
abstract::Crimean-Congo hemorrhagic fever (CCHF) is endemic in Turkey, with peak incidence of hospital admissions in the summer months. The aim of this pilot study was to evaluate the role of the severity grading score (SGS) in predicting length of hospital stay, laboratory usage, need for blood products, and hence total costs ...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1080/20477724.2015.1136130
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Efforts to curb the spread of HIV transmission through transfusion of blood and its products is still a problem because of challenge in countries using antibody-based rapid methods to detect infection during window period. Transmission of HIV through infected blood and its products accounts for approximately...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1080/20477724.2016.1205311
更新日期:2016-06-01 00:00:00
abstract::Many neglected tropical diseases, including the zoonotic disease cystic echinococcosis (hydatidosis), are endemic to East Africa. However, their geographical distribution is heterogenous and incompletely characterized. The aim of this study was to determine if Mundari pastoralists harbor endemic human hydatidosis. The...
journal_title:Pathogens and global health
pub_type: 杂志文章
doi:10.1179/2047773213Y.0000000111
更新日期:2013-09-01 00:00:00