Abstract：
:Sleep timing shifts later during adolescence, thus conflicting with early school start times. This can lead to irregular weekday-weekend schedules and circadian misalignment, which have been linked to depression and substance abuse, consistent with disruptions in the processing of rewards. We tested associations between weekend-weekday shifts in sleep timing and the neural response to monetary reward in healthy adolescents, using actigraphy and a functional magnetic resonance imaging paradigm. Region-of-interest analyses focused on the medial prefrontal cortex (mPFC) and striatum, both of which are implicated in reward function. Analyses adjusted for pubertal stage, sex, and total sleep time. Greater weekend-weekday advances in midsleep were associated with decreased mPFC and striatal reactivity to reward, which could reflect reduced regulatory response and reward sensitivity. We speculate that circadian misalignment associated with weekend shifts in sleep timing may contribute to reward-related problems such as depression and substance abuse.
journal_name
Biol Psycholjournal_title
Biological psychologyauthors
Hasler BP,Dahl RE,Holm SM,Jakubcak JL,Ryan ND,Silk JS,Phillips ML,Forbes EEdoi
10.1016/j.biopsycho.2012.08.008subject
Has Abstractpub_date
2012-12-01 00:00:00pages
334-41issue
3eissn
0301-0511issn
1873-6246pii
S0301-0511(12)00173-1journal_volume
91pub_type
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journal_title：Biological psychology
pub_type： 杂志文章
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journal_title：Biological psychology
pub_type： 杂志文章
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更新日期：2010-09-01 00:00:00
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pub_type： 杂志文章
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abstract：:The current study investigated links between trauma exposure, Post-traumatic Stress Disorder (PTSD) symptoms, and inhibitory control assessed using a modified version of the visual flanker task. The study had three aims: (1) specifically confirm general non-affective deficits in sustained attention in PTSD; (2) probe ...
journal_title：Biological psychology
pub_type： 杂志文章
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pub_type： 临床试验,杂志文章
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journal_title：Biological psychology
pub_type： 杂志文章,随机对照试验
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pub_type： 杂志文章
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更新日期：2016-04-01 00:00:00
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journal_title：Biological psychology
pub_type： 杂志文章
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更新日期：2018-07-01 00:00:00
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doi：10.1016/j.biopsycho.2012.12.007
更新日期：2013-04-01 00:00:00
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journal_title：Biological psychology
pub_type： 杂志文章
doi：10.1016/j.biopsycho.2010.01.013
更新日期：2010-05-01 00:00:00
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journal_title：Biological psychology
pub_type： 杂志文章
doi：10.1016/j.biopsycho.2011.10.016
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journal_title：Biological psychology
pub_type： 杂志文章
doi：10.1016/j.biopsycho.2014.02.008
更新日期：2014-05-01 00:00:00
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更新日期：2020-02-01 00:00:00
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更新日期：2014-02-01 00:00:00
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pub_type： 杂志文章
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journal_title：Biological psychology
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更新日期：2013-02-01 00:00:00
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pub_type： 杂志文章
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abstract：:The aim of this study was to determine the relationship between motor skill and attentional reserve. Participants practiced a reaching task with the dominant upper extremity, to which a distortion of the visual feedback was applied, while a control group performed the same task without distortion. Event-related brain ...
journal_title：Biological psychology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.biopsycho.2014.10.008
更新日期：2014-12-01 00:00:00
