Medical and economic implications of cognitive and psychiatric disability of survivorship.

abstract：:Antibiotic resistance has emerged as a key determinant of outcome in patients with serious infections along with the virulence of the underlying pathogen. Within the intensive care unit (ICU) setting, ventilator-associated pneumonia (VAP) is a common nosocomial infection that is frequently caused by multidrug-resistan...

journal_title：Seminars in respiratory and critical care medicine

authors： Kollef MH,Burnham CD

更新日期：2017-06-01 00:00:00

abstract：:Critically ill intensive care unit (ICU) patients often require sedation to tolerate life-saving interventions such as mechanical ventilation. Pain, anxiety, and delirium all contribute to patient distress and agitation which can interfere with ICU medical care if not addressed and treated appropriately. Sedation prac...

journal_title：Seminars in respiratory and critical care medicine

authors： DeBiasi EM,Akgün KM,Pisani M

更新日期：2015-12-01 00:00:00

abstract：:Sarcoidosis is by definition a disease of "unknown causes," but recent epidemiologic advances suggest that the long-standing definition of sarcoidosis may soon need to be amended. The recently completed ACCESS (A Case-Control Etiologic Study of Sarcoidosis) study was not able to definitively identify the "cause" of sa...

journal_title：Seminars in respiratory and critical care medicine

authors： Rybicki BA,Iannuzzi MC

更新日期：2007-02-01 00:00:00

abstract：:Severe chronic obstructive pulmonary disease (COPD) exacerbations requiring hospitalization are a major cause of morbidity and mortality. Recognition of the importance of COPD exacerbations has led to the knowledge that prevention of exacerbations and early treatment are important goals of COPD therapy. Preventive man...

journal_title：Seminars in respiratory and critical care medicine

authors： Bourbeau J

更新日期：2010-06-01 00:00:00

abstract：:Nonneoplastic pulmonary lymphoid disorders consist of a complex spectrum of diseases for pathologists and pulmonologists alike. Advances in our understanding of these disorders in recent years have led to revisions in the classification scheme. This review summarizes the clinicoradiological and pathological features o...

journal_title：Seminars in respiratory and critical care medicine

authors： Tian X,Yi ES,Ryu JH

更新日期：2012-10-01 00:00:00

abstract：:Non-small cell lung cancer (NSCLC) is primarily a disease of the elderly. Although NSCLC is the leading cause of cancer death in the United States and the overall prognosis of this disease is poor, treatment improves survival compared with best supportive care, independent of the stage of disease. Elderly patients hav...

journal_title：Seminars in respiratory and critical care medicine

authors： Sequist LV,Fidias P

更新日期：2005-06-01 00:00:00

abstract：:Cystic fibrosis (CF) is now more common in adults than children in countries with well-developed health care systems. The number of adults continues to increase and will further increase if the new cystic fibrosis transmembrane conductance regulator (CFTR) modulators are disease modifying. Most of the complex morbidit...

journal_title：Seminars in respiratory and critical care medicine

authors： Elborn JS

更新日期：2019-12-01 00:00:00

abstract：:Healthcare-associated pneumonia (HCAP) represents one of the largest subsets of patients with pneumonia. Based on epidemiological projections for the aging U.S. population, the number of hospitalizations for HCAP is expected to increase exponentially for the next several decades. The unique risk factors for colonizati...

journal_title：Seminars in respiratory and critical care medicine

authors： Morrow LE

更新日期：2009-02-01 00:00:00

abstract：:Patients admitted to the neuroscience intensive care unit (NICU) may have respiratory compromise from either central or peripheral neurological pathology, and may hence require intubation and mechanical ventilation for very diverse reasons. Liberation from invasive ventilation, that is, extubation, at the earliest pos...

journal_title：Seminars in respiratory and critical care medicine

authors： Bösel J

更新日期：2017-12-01 00:00:00

abstract：:Sarcoidosis is an immune-mediated systemic syndrome of unknown etiology. The treatment of the granulomatous inflammation in sarcoidosis is thus dependent on nonspecific suppression of the immune response. Although steroid-sparing approaches have moved to front-line therapy for many other immune-mediated inflammatory d...

journal_title：Seminars in respiratory and critical care medicine

authors： Lazar CA,Culver DA

更新日期：2010-08-01 00:00:00

abstract：:Among immunocompromised individuals, members of the human Herpesviridae family are frequently encountered pathogens. Cytomegalovirus, herpes simplex virus 1 and 2, varicella zoster virus, Epstein-Barr virus, and human herpesvirus-6, -7, and -8 all establish latency after infection and can reactivate during periods of ...

journal_title：Seminars in respiratory and critical care medicine

authors： Reid GE,Lynch JP 3rd,Weigt S,Sayah D,Belperio JA,Grim SA,Clark NM

更新日期：2016-08-01 00:00:00

abstract：:Cryptococcosis is an invasive fungal infection (IFI), caused predominantly by Cryptococcus neoformans or Cryptococcus gattii, that affects both immunocompromised (IC) and non-IC patients. Although the most serious disease manifestation is meningoencephalitis, cryptococcal pneumonia is underdiagnosed and may disseminat...

journal_title：Seminars in respiratory and critical care medicine

authors： Brizendine KD,Baddley JW,Pappas PG

更新日期：2011-12-01 00:00:00

abstract：:A significant number of drugs and toxins have been associated with eosinophilic pneumonia. Antibiotics and NSAID, are the most commonly reported drugs. Toxins suspected to cause eosinophilic pneumonia include cigarette smoke and illicit drugs. Drug- or toxin-induced eosinophilic pneumonia is indistinguishable from idi...

journal_title：Seminars in respiratory and critical care medicine

authors： Solomon J,Schwarz M

更新日期：2006-04-01 00:00:00

abstract：:Lung-protective ventilator strategies are considered standard practice in the care of patients with the acute respiratory distress syndrome (ARDS). To minimize ventilator-induced lung injury, attention is directed at avoidance of alveolar overdistention and cyclical opening and closing. The lowest possible plateau pre...

journal_title：Seminars in respiratory and critical care medicine

authors： Hess DR

更新日期：2014-08-01 00:00:00

abstract：:The use of predictive models has been proposed as a potential tool to reduce maternal morbidity and mortality, by aiding in the timely identification of potential high-risk patients. Prognostic models in critical care have been used to characterize the severity of illness of specific diseases. Physiological changes in...

journal_title：Seminars in respiratory and critical care medicine

authors： Levinson A,Miranda J,Rojas-Suarez JA

更新日期：2017-04-01 00:00:00

abstract：:Bleeding from gastroesophageal varices is a frequent complication of cirrhosis. Mortality from a variceal bleeding episode has decreased in the last 2 decades from 40% to 15 to 20% due to the implementation of effective treatments and improvement in the general medical care. Initial treatment should include adequate f...

journal_title：Seminars in respiratory and critical care medicine

authors： García-Pagán JC,Reverter E,Abraldes JG,Bosch J

更新日期：2012-02-01 00:00:00

abstract：:Lung transplantation is a therapeutic option for patients with end stage lung diseases, but long-term survival remains poor, primarily due to chronic allograft rejection. Bronchiolitis obliterans (BO), a fibrotic process resulting in progressive narrowing of bronchiolar lumens and airflow obstruction, is a manifestati...

journal_title：Seminars in respiratory and critical care medicine

authors： Belperio JA,Lake K,Tazelaar H,Keane MP,Strieter RM,Lynch JP 3rd

更新日期：2003-10-01 00:00:00

abstract：:Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease of unknown cause, occurring in adults, limited to the lungs and associated with the pathologic and radiologic pattern of usual interstitial pneumonia. Prognosis is poor, and most patients die of respiratory failure within 3 to 6 years from the o...

journal_title：Seminars in respiratory and critical care medicine

authors： Puglisi S,Torrisi SE,Giuliano R,Vindigni V,Vancheri C

更新日期：2016-06-01 00:00:00

abstract：:Usual interstitial pneumonia (UIP) is a distinct histological lesion observed in idiopathic pulmonary fibrosis (IPF) but can be found in other etiologies. The diagnosis of UIP can be established by surgical lung biopsy or by high-resolution thin-section computed tomographic (CT) scans (provided the radiographic featur...

journal_title：Seminars in respiratory and critical care medicine

authors： Lynch JP 3rd,Saggar R,Weigt SS,Zisman DA,White ES

更新日期：2006-12-01 00:00:00

abstract：:Invasive fungal infections, especially candidemia and systemic candidiasis, have become a major cause of morbidity and mortality in the last few decades. This comes in parallel with the major advances made in intensive care. Patients who are critically ill, in medical or surgical ICUs are especially at risk for CANDID...

journal_title：Seminars in respiratory and critical care medicine

authors： Vazquez JA

更新日期：2010-02-01 00:00:00

abstract：:Shock is a broad category of injury to the human body caused by a variety of insults. Fluid resuscitation is the cornerstone of initial therapy for nearly all forms of shock. This article reviews the basic physiology determining body fluid composition, the goals of fluid resuscitation in shock, the types of fluids ava...

journal_title：Seminars in respiratory and critical care medicine

authors： Martin GS,Lewis CA

更新日期：2004-12-01 00:00:00

abstract：:Acinetobacter baumannii is a highly resilient, gram-negative coccobacillus that thrives within the unique and complex ecological setting of an intensive care unit. This evolving pathogen has now surpassed human capacity to create new antimicrobials, and has led physicians into a concerning era for hospital-acquired in...

journal_title：Seminars in respiratory and critical care medicine

authors： Peleg AY

更新日期：2007-12-01 00:00:00

abstract：:Antimicrobial resistance has generally increased over the past 5 decades, with occasional brief respites following the introduction of new antimicrobial classes. Resistance has been driven by bacterial genetic events, antibiotic pressures, and lapses in hospital hygiene. Recently promoted solutions to the problem of h...

journal_title：Seminars in respiratory and critical care medicine

authors： Weinstein RA

更新日期：2003-02-01 00:00:00

abstract：:This review summarizes the effects of beta2-agonists on asthma severity. There has been a controversy as to whether the regularly scheduled use of beta2-adrenergic agonists increases the risk of adverse outcomes in asthma. A number of epidemiological and clinical studies have found an association between the regularly...

journal_title：Seminars in respiratory and critical care medicine

authors： Ford JG,Iqbal J,Sunmonu Y

更新日期：2002-08-01 00:00:00

abstract：:Venous thromboembolism (VTE) is a frequent complication in surgical patients, with the potential for long-term disability or fatal outcome. The rationale behind routine use of thromboprophylaxis can be summarized in three points: (1) VTE is frequent in certain surgical populations, (2) VTE may be fatal, (3) thrombopro...

journal_title：Seminars in respiratory and critical care medicine

authors： Petralia GA,Kakkar AK

更新日期：2008-02-01 00:00:00

abstract：:Pneumothorax is a common clinical entity that may present to a wide variety of medical specialties. Primary pneumothorax (in the presence of no known underlying lung disease) and secondary pneumothorax (in known lung disease) are distinct entities with varied etiology, treatment, and prognosis. Diagnosis is usually ba...

journal_title：Seminars in respiratory and critical care medicine

authors： Rahman NM,Davies RJ,Gleeson FV

更新日期：2008-08-01 00:00:00

abstract：:Over the past 3 decades, antimicrobial resistance among Streptococcus pneumoniae, the most common cause of community-acquired pneumonia (CAP), has escalated dramatically worldwide. In the late 1970s, strains of pneumococci displaying resistance to penicillin were described in South Africa and Spain. By the early 1990s...

journal_title：Seminars in respiratory and critical care medicine

authors： Lynch JP 3rd,Zhanel GG

更新日期：2009-04-01 00:00:00

abstract：:In heart failure (HF), pleural effusion results from increased interstitial fluid in the lung due to elevated pulmonary capillary pressure. Rarely, pleural effusions may occur in association with isolated right HF. HF-associated effusions are typically bilateral, but if unilateral, they are more commonly seen on the r...

journal_title：Seminars in respiratory and critical care medicine

authors： Porcel JM

更新日期：2010-12-01 00:00:00

abstract：:This review provides an update on literature published over the past 5 years that is relevant to using chest computed tomography (CT) as a tool for preventing occupational respiratory disease. An important area of investigation has been in the use of low-dose CT (LDCT) to screen asbestos-exposed populations for lung c...

journal_title：Seminars in respiratory and critical care medicine

authors： Weissman DN

更新日期：2015-06-01 00:00:00

abstract：:Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is the third most common cardiovascular pathology after coronary disease and cerebrovascular diseases and is responsible for significant morbidity and mortality in the general population. Full-dose anticoagulation is the st...

journal_title：Seminars in respiratory and critical care medicine

authors： Imberti D,Maraldi C,Gallerani M

更新日期：2012-04-01 00:00:00