Abstract:
:This experimental study was undertaken in mice to investigate the procedures for storage of allogenic cancellous bone. Cancellous grafts were were stored at -80 degrees C, -196 degrees C or freeze dried. Grafts were implanted into a defect in the recipient's femur and after one week the cellular kinetic activity was analysed by autoradiography. For immunological study, the grafts were implanted into the recipient's muscle, and 2 weeks later the sensitising properties were examined by killer T-cell toxicity and the complement dependent cytotoxicity test. The capacity for osteogenesis of grafts frozen at -196 degrees C was similar to or higher than those freeze dried, but it was low when storage was at -80 degrees C. Immunogenicity was not affected by these three methods of storage and was very similar to that of fresh autografts. Antigenicity of allografts can be decreased by the freezing procedure. We suggest that the greater osteogenic potency after freezing at 196 degrees C is related to the lesser degree of degeneration of the bone matrix.
journal_name
Int Orthopjournal_title
International orthopaedicsauthors
Mizutani A,Fujita T,Watanabe S,Sakakida K,Okada Ydoi
10.1007/BF00178753subject
Has Abstractpub_date
1990-01-01 00:00:00pages
243-8issue
3eissn
0341-2695issn
1432-5195journal_volume
14pub_type
杂志文章abstract::We developed a locking screw plate system for the stabilisation of distal radial fractures, which can be inserted through a standard volar approach and in which the locking mechanism allows early post-operative mobilisation. Forty-nine patients with 50 fractures underwent surgical treatment; 66% were type C fractures....
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-002-0393-x
更新日期:2003-01-01 00:00:00
abstract:PURPOSE:Despite bilateral knee replacement being frequently performed, little data is available to inform on the relative outcomes of each knee for individual patients. The purpose of this study was to compare these outcomes in a series of bilateral total knee replacements (TKRs) performed either simultaneously or at a...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-016-3122-6
更新日期:2016-10-01 00:00:00
abstract:PURPOSE:The aim of our study was to evaluate the effect of the S3 (spatial subchondral support) humeral plate and to compare the clinical outcomes and complications after ORIF (open reduction and internal fixation) of proximal humeral fractures using either a S3 plate or a PHLP (proximal humeral locking plate). METHOD...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-015-2705-y
更新日期:2015-06-01 00:00:00
abstract:PURPOSE:Osteoporosis mainly involves cancellous bone, and the spine and hip, with their relatively high cancellous bone to cortical bone ratio, are severely affected. Studies of bone mesenchymal stem cells (BMSCs) from osteoporotic patients and animal models have revealed that osteoporosis is often associated with redu...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-012-1543-4
更新日期:2012-10-01 00:00:00
abstract:PURPOSE:To evaluate the regenerative potential of surnatants (SNs) from bone marrow concentrate (SN-BMC) and expanded mesenchymal stromal cells (SN-MSCs) loaded onto a collagen scaffold (SC) in comparison with cell-based treatments (BMC and MSCs) in an osteochondral (OC) defect model in rabbits. METHODS:OC defects (3 ...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-018-4202-6
更新日期:2019-01-01 00:00:00
abstract::We used scanning electron microscopy to perform an ultrastructural analysis and two optical interferometric profilers to measure roughness on 40 prosthetic femoral heads. We expressed roughness as Ra (roughness average) value and Rsk (roughness skewness) value. Our results show that in order to obtain an ideal surface...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s002640000129
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Periprosthetic tissue cultures, sonication and synovial fluid cultures remain the gold standard for prosthetic joint infection (PJI) diagnosis. However, some 15-20% culture-negative PJI are still reported. Therefore, there is the need for other diagnostic criteria. One point of concern relative to the differ...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-017-3430-5
更新日期:2017-07-01 00:00:00
abstract:PURPOSE:Loosening of implants occurs mainly for two reasons: bacterial infection of the implant or "aseptic loosening" presumably due to wear particles derived from the implant. To gain further insight into the pathomechanism, we analysed activation of the T cell response in these patients. METHODS:Activation of perip...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-014-2310-5
更新日期:2014-06-01 00:00:00
abstract:PURPOSE:The aims of this retrospective study were to firstly introduce three practical bulk bone graft techniques based on acetabular morphology for dysplasia and secondly evaluate the long-term durability of acetabular reconstruction using those techniques combined with cemented total hip arthroplasty (THA). METHODS:...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-015-3039-5
更新日期:2016-09-01 00:00:00
abstract::Subluxation of the patella may produce pain and instability in young people. However its classification, diagnosis and treatment are controversial. We have used computerized tomography (CT) to measure the amount of lateral shift of the patella and the angle of tilt to the femur in patients with subluxation. The mean l...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract:PURPOSE:Indications for amputation in natural disasters are not the same compared to our daily practice. They must be determined by those with great surgical experience and good knowledge of military or disaster surgical doctrine. Unfortunately, nowadays few surgeons have this experience. In fact, some volunteer surgeo...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-012-1548-z
更新日期:2012-10-01 00:00:00
abstract::The purpose of this study was to evaluate the relationship between body mass index and early complications following total hip replacements. Five hundred and fifty patients who underwent primary total hip replacement were recruited. All these patients were subjected to a pre-operative assessment and follow-up at 6 wee...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-006-0222-8
更新日期:2007-08-01 00:00:00
abstract::Fifty-four consecutive acute Achilles tendon ruptures were treated with end-to-end suture augmented with gastrocnemius fascial flaps. Surgery was performed within 24 h. Mean patient age was 35 (23-57) years, and 46 were men. Mean follow-up time was 4.8 (2-8) years. At follow-up, the mean visual analogue scale for pain...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-004-0598-2
更新日期:2005-02-01 00:00:00
abstract:PURPOSES:Post arthroplasty gait analysis has up till now been performed on subjects walking slowly on flat ground rather than challenging them at faster speeds or walking uphill. We therefore asked: (1) Is there a measurable difference in the performance of hip resurfacing arthroplasty (HRA) and total hip arthroplasty ...
journal_title:International orthopaedics
pub_type: 临床试验,杂志文章
doi:10.1007/s00264-013-1819-3
更新日期:2013-05-01 00:00:00
abstract::In vitro and in vivo studies have demonstrated the possibility that cancellous bone could be used as a carrier of antibiotics for local delivery. However, the release of antibiotics from the loaded cancellous bone is too rapid and uncertain. We hypothesised that demineralisation of cancellous bone would increase the a...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-002-0384-y
更新日期:2003-01-01 00:00:00
abstract:STUDY DESIGN:This was a retrospective study to evaluate clinical characteristics of patients who developed symptomatic spinal epidural haematoma (SSEH) after spinal surgery. OBJECTIVE:The objective was to determine clinical parameters associated with the development of SSEH after spinal surgery, and to discuss clinica...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-017-3506-2
更新日期:2017-07-01 00:00:00
abstract:PURPOSE:The objective of this report was to analyse injury patterns and definitive management of local casualties with multiple blast extremity injuries in the Kabul International Airport Combat Support Hospital. METHODS:A clinical prospective study was performed from July 2012 to January 2013. Afghan victims of a bla...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-014-2532-6
更新日期:2014-12-01 00:00:00
abstract:PURPOSE:Limited data exist for the reconstructive potential of short bone-preserving stems in THA using a minimal invasive posterolateral approach. Our study aim was to assess the effect of stem design on the reconstruction of hip offset and leg length in MIS posterolateral THA. METHODS:This retrospective consecutive ...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-014-2299-9
更新日期:2014-07-01 00:00:00
abstract::Fourteen femoral stems were implanted either manually by an experienced surgeon or by a robot in fresh human cadaveric femora. The neck-shaft angle, the anteversion, the length of the femoral neck and the gap between stem and bone was measured in each specimen. Implantation by robot showed higher precision in reconstr...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s002640050356
更新日期:1999-01-01 00:00:00
abstract:PURPOSE:The purpose of this study was to assess the effects of operative and non-operative treatment on clavicle fractures. METHOD:Relevant clinical trials on the operative and non-operative treatment for clavicle fractures were retrieved through searching the databases MEDLINE, Embase, OVID and the Cochrane Central R...
journal_title:International orthopaedics
pub_type: 杂志文章,meta分析
doi:10.1007/s00264-013-1871-z
更新日期:2013-08-01 00:00:00
abstract::During a six-year period, eleven persons with primary pyogenic abscess of the psoas muscle were treated at the Mackay Memorial Hospital. Five were males and six were females and their average age was 47.2 years (range 6-83 years). The abscess was identified by CT in 7 patients, MRI in 2 and ultrasonography in 1. One a...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s002640050205
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:This prospective randomized trial is to determine the effectiveness of treating lumbar facet syndrome with oral diclofenac, methylprednisolone facet joint injection or both. METHODS:We enrolled lumbar facet syndrome patients treated at Srinagarind Hospital. Enrolled patients were randomly assigned to receive 1...
journal_title:International orthopaedics
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00264-016-3154-y
更新日期:2016-06-01 00:00:00
abstract:PURPOSE:Extracorporeal shockwave therapy (ESWT) has become a common practice for treating knee osteoarthritis (OA). However, the effectiveness and safety of this treatment are still questionable. This meta-analysis is aimed at determining the degree of pain reduction and functional outcome after ESWT for knee OA. METH...
journal_title:International orthopaedics
pub_type: 杂志文章,评审
doi:10.1007/s00264-020-04489-x
更新日期:2020-05-01 00:00:00
abstract::The purpose of this study was to investigate the effects of addition of antibiotics into cement powder on the shear properties of the cement-metal interface. The approach involved adding 800 mg of teicoplanin to 40 g bone cement powder in the t-800 group, 1,600 mg teicoplanin in the t-1,600 group, and no antibiotic in...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-007-0347-4
更新日期:2008-08-01 00:00:00
abstract::Results of two methods, conventional open reduction-internal plating and minimally invasive plating osteosynthesis (MIPO), in the treatment of mid-distal humeral shaft fractures were compared. Thirty-three patients were retrospectively analysed and divided into two groups. Group A (n = 17) patients were treated by MIP...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-009-0753-x
更新日期:2010-02-01 00:00:00
abstract::A 21 year old Japanese male of normal intelligence with severe athetosis, scoliosis with pelvic obliquity, and a positive Galant's reflex was seen with complaint of difficulty in maintaining a sitting posture. After release of the soft tissues around the hip and axilla, followed by physiotherapy, he underwent ipsilate...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/BF00271094
更新日期:1980-01-01 00:00:00
abstract:PURPOSE:We investigated if patient-reported outcomes (PROMs) one year after total hip replacement (THR) can predict the risk of re-operation using data from the Swedish Hip Arthroplasty Register. METHODS:A total of 75,899 patients with THR due to osteoarthritis operated in 2002-2014 were included. We used Kaplan-Meier...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-017-3711-z
更新日期:2018-02-01 00:00:00
abstract::We measured the size and volume of the femoral broaches and stems supplied with three commercial total hip replacement (THR) systems (JRI Furlong, Biomet Stanmore, and Howmedica Exeter). Using an in vitro method, we created cement mantles that could be directly measured. The broaches supplied with the Biomet Stanmore ...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-003-0509-y
更新日期:2004-02-01 00:00:00
abstract::Bony defects caused by trauma, tumors, infection or congenital anomalies can present a significant surgical challenge. Free vascularised fibular bone grafts (FVFGs) have proven to be extremely effective in managing larger defects (longer than 6 cm) where other conventional grafts have failed. FVFGs also have a role in...
journal_title:International orthopaedics
pub_type: 杂志文章,评审
doi:10.1007/s00264-014-2281-6
更新日期:2014-06-01 00:00:00
abstract::The purpose of this study was to assess the referral system, clinical notes and radiographs of patients presenting with metastatic disease of long bones. The study demonstrated that 93% of oncologists did not use a reliable scoring system to assess risk of pathological fracture, and 60% felt an improvement in communic...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-008-0556-5
更新日期:2009-04-01 00:00:00