Comparison of cardiopulmonary responses during 2 incremental step tests in subjects with COPD.

Abstract:

BACKGROUND:It is well established that the work rate increment size affects the duration of test and physiological responses to exercise during cycling in patients with COPD. However, this has never been tested for incremental step tests. OBJECTIVE:To compare the exercise tolerance time, cardiopulmonary stress, and perception of effort between the Chester step test (CST) and a modified incremental step test (MIST). METHODS:Thirty-two subjects with COPD (FEV(1) 50 ± 15% of predicted) were randomized to perform the CST and MIST on the same day, an hour apart, on a single step (20 cm high). During tests, pulmonary gas exchange was measured continuously by a portable metabolic system. RESULTS:CST had shorter duration and also lower number of steps, in comparison with MIST. However, similar cardiopulmonary responses were observed at exercise peak: oxygen uptake (V(.)(O(2))) 1.22 ± 0.59 L/min vs 1.24 ± 0.55 L/min, minute ventilation (V(.)(E)) 30.8 ± 12.7 L/min vs 30.0 ± 11.7 L/min, heart rate 86 ± 13 beats/min vs 85 ± 13 beats/min, and S(pO(2)) 87 ± 7% vs 87 ± 6%. Dyspnea and leg fatigue scores when correcting for exercise duration were higher for CST. CONCLUSIONS:The slower the work rate increment during step test, the higher the exercise tolerance. Regardless of the work rate increment, cardiopulmonary stress and exertion effort at peak exercise were equivalent between tests.

journal_name

Respir Care

journal_title

Respiratory care

authors

de Andrade CH,de Camargo AA,de Castro BP,Malaguti C,Dal Corso S

doi

10.4187/respcare.01742

subject

Has Abstract

pub_date

2012-11-01 00:00:00

pages

1920-6

issue

11

eissn

0020-1324

issn

1943-3654

pii

rc01742r1andrade

journal_volume

57

pub_type

杂志文章
  • Emerging gram-negative antibiotic resistance: daunting challenges, declining sensitivities, and dire consequences.

    abstract::Emerging antibiotic resistance has created a major public health dilemma, compounded by a dearth of new antibiotic options. Multidrug-resistant Gram-negative organisms have received less attention than Gram-positive threats, such as methicillin-resistant Staphylococcus aureus, but are just as menacing. Pathogens such ...

    journal_title:Respiratory care

    pub_type: 杂志文章,评审

    doi:

    authors: Siegel RE

    更新日期:2008-04-01 00:00:00

  • Should Aerosolized Antibiotics Be Used to Treat Ventilator-Associated Pneumonia?

    abstract::In patients with ventilator-associated pneumonia, systemic use of antibiotics is the cornerstone of medical management. Supplemental use of aerosolized antibiotics with intravenous antibiotics in both experimental and clinical studies has been shown to have the following pharmacologic benefits: (1) aerosolized antibio...

    journal_title:Respiratory care

    pub_type: 杂志文章,评审

    doi:10.4187/respcare.04748

    authors: Zhang C,Berra L,Klompas M

    更新日期:2016-06-01 00:00:00

  • The Concave Shape of the Forced Expiratory Flow-Volume Curve in 3 Seconds Is a Practical Surrogate of FEV1/FVC for the Diagnosis of Airway Limitation in Inadequate Spirometry.

    abstract:BACKGROUND:Spirometry is important for the differential diagnosis of dyspnea. However, some patients cannot exhale for ≥6 s to achieve the American Thoracic Society/European Respiratory Society criteria. The aim of this study was to demonstrate the reliability of a new parameter that quantifies the degree of concavity ...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:10.4187/respcare.05016

    authors: Li H,Liu C,Zhang Y,Xiao W

    更新日期:2017-03-01 00:00:00

  • Hypoxemia during sleep in patients with chronic obstructive pulmonary disease: significance, detection, and effects of therapy.

    abstract::NOD is a common event in patients with symptomatic COPD who are not hypoxemic while awake. Up to 45% of these patients may have significant oxyhemoglobin desaturation during sleep, and most have evidence of pulmonary arterial hypertension. Although intuitively it would seem that supplemental oxygen during sleep should...

    journal_title:Respiratory care

    pub_type: 杂志文章,评审

    doi:

    authors: O'Donohue WJ Jr,Bowman TJ

    更新日期:2000-02-01 00:00:00

  • The physiologic effects of noninvasive ventilation.

    abstract::The physiologic effects of noninvasive ventilation (NIV) on work of breathing (WOB) and breathing pattern, respiratory-system mechanics, and hemodynamic function were examined via a literature review of clinical studies done between 1990 and 2008. Forty-one relevant studies were found; the majority examined patients w...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:

    authors: Kallet RH,Diaz JV

    更新日期:2009-01-01 00:00:00

  • Sleep-disordered breathing and COPD: the overlap syndrome.

    abstract::Sleep-disordered breathing (mainly obstructive sleep apnea [OSA]) and COPD are among the most common pulmonary diseases, so a great number of patients have both disorders; this "overlap syndrome" causes more severe nocturnal hypoxemia than either disease alone. This common combination of OSA and COPD has important imp...

    journal_title:Respiratory care

    pub_type: 杂志文章,评审

    doi:

    authors: Owens RL,Malhotra A

    更新日期:2010-10-01 00:00:00

  • Respiratory controversies in the critical care setting. Should heliox be used for mechanically ventilated patients?

    abstract::Helium is an inert gas with a very low density (0.18 g/L), which allows it to pass through narrowed passages with less turbulence than nitrogen or oxygen. For many years, helium-oxygen mixture (heliox) has been used for patients with severe airway obstruction. However, the data supporting the clinical application of h...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:

    authors: Hurford WE,Cheifetz IM

    更新日期:2007-05-01 00:00:00

  • Staffing exercise sessions in pulmonary rehabilitation.

    abstract:INTRODUCTION:There is no published standard for the ratio of staff to patients during exercise sessions in outpatient pulmonary rehabilitation. This lack of a standard raises concern about patient safety and the ability to monitor patients adequately. OBJECTIVE:Determine a staff-to-patient ratio standard by examining ...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:

    authors: Hoberty PD,Chiu CY,Hoberty RJ

    更新日期:2001-07-01 00:00:00

  • Reciprocal influence of refractory hypoxemia and high intracranial pressure on the postoperative management of an urgent neurosurgical procedure.

    abstract::A 20-year-old man was admitted in the neurology ICU after the drainage of a large frontal hematoma related to the spontaneous bleeding of a recently diagnosed cavernoma. On admission the Glasgow coma score was 4/15, with evidence of sub-falcorial herniation and elevated intracranial pressure. On the 4th postoperative...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:10.4187/respcare.01322

    authors: Vanhoonacker M,Roeseler J,Hantson P

    更新日期:2012-07-01 00:00:00

  • Factors affecting the job satisfaction of respiratory therapists who work in adult general and critical care: a multivariate study.

    abstract:UNLABELLED:The development of an expanded understanding of employees' reaction to their job may be important for improvement in the quality of work life and of services rendered. We sought to determine the factors, or rewards, that significantly affect respiratory therapists' job satisfaction. METHOD:Questionnaires de...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:

    authors: Akroyd HD,Robertson R

    更新日期:1989-03-01 00:00:00

  • Safety and efficacy of short-term intrapulmonary percussive ventilation in patients with bronchiectasis.

    abstract:BACKGROUND:Treatment of bronchiectasis includes drugs, oxygen therapy, and bronchial-clearance maneuvers. OBJECTIVE:To assess the safety and efficacy of intrapulmonary percussive ventilation (IPV) compared to traditional standard chest physical therapy in patients with bronchiectasis and productive cough. METHODS:In ...

    journal_title:Respiratory care

    pub_type: 杂志文章,随机对照试验

    doi:10.4187/respcare.01098

    authors: Paneroni M,Clini E,Simonelli C,Bianchi L,Degli Antoni F,Vitacca M

    更新日期:2011-07-01 00:00:00

  • Heliox and forward-leaning posture improve the efficacy of nebulized bronchodilator in acute asthma: a randomized trial.

    abstract:BACKGROUND:Heliox and forward-leaning posture (torso inclined forward at 50-60° with the elbows resting on the thighs) are adjuncts in the administration of nebulized bronchodilator to patients with acute asthma. METHODS:We randomized 59 patients who presented to the emergency department in severe asthma crisis, into ...

    journal_title:Respiratory care

    pub_type: 杂志文章,随机对照试验

    doi:10.4187/respcare.00963

    authors: Brandão DC,Britto MC,Pessoa MF,de Sá RB,Alcoforado L,Matos LO,Silva TN,de Andrade AD

    更新日期:2011-07-01 00:00:00

  • Relationship between functional residual capacity, respiratory compliance, and oxygenation in patients ventilated after cardiac surgery.

    abstract:BACKGROUND:Measurement of functional residual capacity (FRC) is now possible at bedside, during mechanical ventilation. OBJECTIVES:To determine the relationship of measured absolute and relative predicted FRC values to oxygenation and respiratory-system compliance, and to identify variables that influence FRC in venti...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:

    authors: Heinze H,Sedemund-Adib B,Heringlake M,Meier T,Eichler W

    更新日期:2010-05-01 00:00:00

  • Quality assurance of the pulmonary function technologist.

    abstract::The skill and work habits of the pulmonary function technologist are central to the quality of patient testing. Pulmonary function technologists should be chosen carefully. The pulmonary function technologists must be intelligent, conscientious, and possess critical thinking skills. Studies are needed to better ident...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:10.4187/respcare.01401

    authors: Haynes JM

    更新日期:2012-01-01 00:00:00

  • Chest radiography validity in screening pulmonary tuberculosis in immigrants from a high-burden country.

    abstract:BACKGROUND:Chest x-ray (CXR) is widely used for diagnosing and screening pulmonary tuberculosis (PTB), yet its validity is debatable and its costs are relatively high. This study aimed to determine the validity of CXR screening in detecting radiological findings compatible with active PTB or with old healed tuberculos...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:10.4187/respcare.01475

    authors: Mor Z,Leventhal A,Weiler-Ravell D,Peled N,Lerman Y

    更新日期:2012-07-01 00:00:00

  • Mechanical ventilator design and function: the trigger variable.

    abstract::Because of the design characteristics, flow-triggering appears to offer measurable advantages over pressure-triggering, particularly during spontaneous breathing. During the trigger phase, flow-triggering provides a relatively shorter time delay than pressure-triggering. A trigger sensitivity that does not cause autoc...

    journal_title:Respiratory care

    pub_type: 共识发展会议,杂志文章,评审

    doi:

    authors: Sassoon CS

    更新日期:1992-09-01 00:00:00

  • Practical tips for working effectively with your institutional review board.

    abstract::The federal government regulates human research with a local institutional review board (IRB) at your institution. Your IRB's main responsibility is to protect the rights and welfare of human subjects recruited to participate in research. The IRB is responsible for reviewing and approving all research protocols that i...

    journal_title:Respiratory care

    pub_type: 杂志文章,评审

    doi:

    authors: Schwenzer KJ

    更新日期:2008-10-01 00:00:00

  • Limits of effective cough-augmentation techniques in patients with neuromuscular disease.

    abstract:BACKGROUND:Manual and mechanical cough-augmentation techniques can improve peak cough flow (PCF) in patients with respiratory insufficiency caused by neuromuscular disease. METHODS:We studied cough-augmentation techniques in 179 clinically stable patients with various neuromuscular diseases. We measured vital capacity...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:

    authors: Toussaint M,Boitano LJ,Gathot V,Steens M,Soudon P

    更新日期:2009-03-01 00:00:00

  • Prediction of pneumonia 30-day readmissions: a single-center attempt to increase model performance.

    abstract:BACKGROUND:Existing models developed to predict 30 days readmissions for pneumonia lack discriminative ability. We attempted to increase model performance with the addition of variables found to be of benefit in other studies. METHODS:From 133,368 admissions to a tertiary-care hospital from January 2009 to March 2012,...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:10.4187/respcare.02563

    authors: Mather JF,Fortunato GJ,Ash JL,Davis MJ,Kumar A

    更新日期:2014-02-01 00:00:00

  • Bench assessment of a new insufflation-exsufflation device.

    abstract:BACKGROUND:The Nippy Clearway is a new mechanical insufflation-exsufflation device used to assist cough. METHODS:We compared the peak expiratory flow (PEF) with the Nippy Clearway versus the CoughAssist in a bench experiment. The relationship between PEF and pressure at the airway opening during exsufflation (minimum ...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:10.4187/respcare.02345

    authors: Porot V,Guérin C

    更新日期:2013-09-01 00:00:00

  • Idiopathic pulmonary fibrosis with emphysema: evidence of synergy among emphysema and idiopathic pulmonary fibrosis in smokers.

    abstract:BACKGROUND:Emphysema and fibrosis, typically the idiopathic pulmonary fibrosis (IPF) form of usual interstitial pneumonia (UIP), can co-exist as combined pulmonary fibrosis emphysema (CPFE). It is unknown whether there is a pathobiologic basis for CPFE beyond the coexistence of fibrosis and emphysema. The aim of this s...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:10.4187/respcare.03389

    authors: Mitchell PD,Das JP,Murphy DJ,Keane MP,Donnelly SC,Dodd JD,Butler MW

    更新日期:2015-02-01 00:00:00

  • Adjunct therapies during mechanical ventilation: airway clearance techniques, therapeutic aerosols, and gases.

    abstract::Mechanically ventilated patients in respiratory failure often require adjunct therapies to address special needs such as inhaled drug delivery to alleviate airway obstruction, treat pulmonary infection, or stabilize gas exchange, or therapies that enhance pulmonary hygiene. These therapies generally are supportive in ...

    journal_title:Respiratory care

    pub_type: 杂志文章,评审

    doi:10.4187/respcare.02217

    authors: Kallet RH

    更新日期:2013-06-01 00:00:00

  • Feasibility and Efficacy of Pulsed-Dose Oxygen Delivery During Noninvasive Ventilation.

    abstract:BACKGROUND:It is difficult to apply noninvasive ventilation (NIV) simultaneously with pulsed-dose oxygen delivery. We evaluated the feasibility and efficacy of pulsed-dose oxygen delivery during NIV. METHODS:A bench study was conducted using a simulated lung during NIV, with a breathing frequency of 10 or 20 breaths/m...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:10.4187/respcare.06922

    authors: Li LL,Yang HY,Jin H,Dai B,Peng Y,Tan W

    更新日期:2020-09-01 00:00:00

  • Reduced FEV1/FVC and FEV1 in the Normal Range as a Physiological Variant.

    abstract:BACKGROUND:Healthy individuals without respiratory symptoms can sometimes present with low FEV1/FVC. The objective of this study was to characterize and compare subjects without symptoms and with reduced FEV1/FVC but normal FEV1 with subjects with mild obstructive lung disease. METHODS:Fifty healthy subjects with FEV1...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:10.4187/respcare.06131

    authors: Dos Santos Andreata L,Soares MR,Pereira CA

    更新日期:2019-05-01 00:00:00

  • Impact of Home Oxygen Therapy on the Level of Physical Activities in Daily Life in Subjects With COPD.

    abstract:BACKGROUND:Chronic hypoxemia in patients with COPD is a limiting factor that is associated with disease progression and significantly contributes to decreased physical activity. Although correction of hypoxemia results in physiological improvements, oxygen therapy may be related to social isolation and inactivity. Howe...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:10.4187/respcare.06206

    authors: Cani KC,Matte DL,Silva IJCS,Gulart AA,Karloh M,Mayer AF

    更新日期:2019-11-01 00:00:00

  • Propofol infusion is associated with a higher rapid shallow breathing index in patients preparing to wean from mechanical ventilation.

    abstract:OBJECTIVE:To determine whether propofol affects spontaneous breathing patterns in critically ill patients recovering from respiratory failure during initial attempts at liberation from mechanical ventilation. DESIGN:Observational cohort study. PATIENTS:Ten critically ill patients in the medical intensive care unit of...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:

    authors: Khamiees M,Amoateng-Adjepong Y,Manthous CA

    更新日期:2002-02-01 00:00:00

  • Variation Among Spirometry Interpretation Algorithms.

    abstract::Several algorithms exist to facilitate spirometric interpretation in clinical practice, yet there is a lack of consensus on how spirometric criteria for asthma, COPD, and restrictive disorders should be incorporated into spirometry interpretation algorithms suitable for use in day-to-day primary care management. The p...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:10.4187/respcare.07294

    authors: D'Urzo KA,Mok F,D'Urzo AD

    更新日期:2020-10-01 00:00:00

  • Imaging of acute respiratory distress syndrome.

    abstract::Chest radiography and computed tomography (CT) have a crucial role to play in the diagnosis and management of acute respiratory distress syndrome (ARDS). The identification of pulmonary opacification is a requirement for the definition of ARDS on the chest radiograph, while CT has a role to play, not only in the diag...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:10.4187/respcare.01731

    authors: Sheard S,Rao P,Devaraj A

    更新日期:2012-04-01 00:00:00

  • Practical problems with aerosol therapy in COPD.

    abstract::Inhaled aerosol drugs commonly used by patients with chronic obstructive pulmonary disease include short-acting and long-acting bronchodilators, as well as corticosteroids. These agents are available in a variety of inhaler devices, which include metered-dose inhalers (MDI), breath-actuated MDIs, nebulizers, and, curr...

    journal_title:Respiratory care

    pub_type: 杂志文章,评审

    doi:

    authors: Rau JL

    更新日期:2006-02-01 00:00:00

  • Factors that delay COPD detection in the general elderly population.

    abstract:BACKGROUND:In patients with COPD, early detection and rapid treatment are essential to prevent its progression and exacerbations. OBJECTIVE:To identify factors that delay COPD detection. METHODS:We conducted a cross-sectional study of elderly COPD patients and healthy subjects in rural Japan. We measured respiratory ...

    journal_title:Respiratory care

    pub_type: 杂志文章

    doi:10.4187/respcare.01109

    authors: Horie J,Murata S,Hayashi S,Murata J,Miyazaki J,Mizota K,Horikawa E

    更新日期:2011-08-01 00:00:00