Abstract:
BACKGROUND:Measurement of functional residual capacity (FRC) is now possible at bedside, during mechanical ventilation. OBJECTIVES:To determine the relationship of measured absolute and relative predicted FRC values to oxygenation and respiratory-system compliance, and to identify variables that influence FRC in ventilated patients after cardiac surgery. METHODS:We retrospectively analyzed data from 99 patients ventilated after cardiac surgery. Each patient underwent an alveolar recruitment maneuver and was then ventilated with a positive end-expiratory pressure of 10 cm H2O and a tidal volume of 6-8 mL/kg predicted body weight. We measured quasi-static 2-point compliance of the respiratory system, FRC (with the oxygen-wash-out method), PaO2, and fraction of inspired oxygen (F(I)O2). We indexed the FRC values to predicted FRC reference values from sitting and supine healthy volunteers. RESULTS:Correlation analyses revealed no meaningful association between FRC and PaO2/F(I)O2 (r2 0.20, P < .001). There was a moderate association between absolute FRC and respiratory-system compliance (r2 0.50, P < .001). Indexing the absolute measured FRC values to the predicted FRC values did not improve the correlation. We conducted multiple linear regression analyses of height, weight, age, sex, presence of mild chronic obstructive pulmonary disease, minute volume, and peak inspiratory pressure during ventilation, and revealed weight, minute volume, and peak inspiratory pressure (r2 = 0.65) as independent covariates of FRC. CONCLUSIONS:Indexing the measured FRC values to the predicted supine and sitting FRC values does not improve the association between PaO2/F(I)O2 and respiratory-system compliance. In mechanically ventilated patients after cardiac surgery, FRC is influenced more by the ventilator settings than by physiologic variables (as in spontaneously breathing persons).
journal_name
Respir Carejournal_title
Respiratory careauthors
Heinze H,Sedemund-Adib B,Heringlake M,Meier T,Eichler Wsubject
Has Abstractpub_date
2010-05-01 00:00:00pages
589-94issue
5eissn
0020-1324issn
1943-3654journal_volume
55pub_type
杂志文章相关文献
Respiratory Care文献大全abstract::Because of the design characteristics, flow-triggering appears to offer measurable advantages over pressure-triggering, particularly during spontaneous breathing. During the trigger phase, flow-triggering provides a relatively shorter time delay than pressure-triggering. A trigger sensitivity that does not cause autoc...
journal_title:Respiratory care
pub_type: 共识发展会议,杂志文章,评审
doi:
更新日期:1992-09-01 00:00:00
abstract:BACKGROUND:In this study, we aimed to validate the agreement between pulmonary function measurements obtained with a portable spirometer and measurements obtained with conventional spirometry in Chinese pediatric and adult populations. METHODS:Pulmonary function testing was performed to evaluate subjects enrolled at S...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.07116
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:Asthma is defined by airway inflammation associated with various respiratory symptoms, and pharmacologic treatment is based on inhaled corticosteroids and bronchodilators. Physical activity, educational training, nutritional support, and psychological counseling are considered part of non-pharmacologic treat...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.06761
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Spirometry is important for the differential diagnosis of dyspnea. However, some patients cannot exhale for ≥6 s to achieve the American Thoracic Society/European Respiratory Society criteria. The aim of this study was to demonstrate the reliability of a new parameter that quantifies the degree of concavity ...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.05016
更新日期:2017-03-01 00:00:00
abstract:HYPOTHESIS:We hypothesized that aerosol distribution in the lungs of patients with cystic fibrosis changes with positive expiratory pressure (PEP). METHODS:Eight patients were randomized to one of 2 conditions. On one study day, patients inhaled saline aerosol containing 99mtechnetium generated by a Pari LC Plus nebul...
journal_title:Respiratory care
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2005-11-01 00:00:00
abstract:BACKGROUND:Humidified, high-flow nasal cannula (HFNC) enables mucociliary clearance, accurate oxygen measurement, precise control of flow, and low-level positive airway pressure. There is sparse information concerning the timing of HFNC on patient outcomes such as incidence of adverse events during hospitalization, ICU...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.04016
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:COPD is a leading cause of morbidity and mortality worldwide. Spirometry is the most common lung function test for diagnosing COPD with a post-bronchodilator FEV1/FVC < 0.70 confirming the presence of the disease. However, diagnosticians appear reluctant to use bronchodilators, which have been linked to the ...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.06148
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:This study compared 3 nebulizer technologies for inter- and intradevice reproducibility, humidification, and fill volume sensitivity during mechanical ventilation: a breath-enhanced jet nebulizer, a vibrating mesh nebulizer, and a jet nebulizer. The breath-enhanced jet nebulizer featured a new design located...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.07639
更新日期:2020-10-01 00:00:00
abstract::The cardiopulmonary physiology of dinosaurs-and especially of the long-necked sauropods, which grew much larger than any land animals before or since-should be inherently fascinating to anyone involved in respiratory care. What would the blood pressure be in an animal 12 m (40 ft) tall? How could airway resistance and...
journal_title:Respiratory care
pub_type:
doi:10.4187/002013209793800286
更新日期:2009-07-01 00:00:00
abstract:INTRODUCTION:A mass-casualty respiratory failure event where patients exceed available ventilators has spurred several proposed solutions. One proposal is use of a single ventilator to support 4 patients. METHODS:A ventilator was modified to allow attachment of 4 circuits. Each circuit was connected to one chamber of...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.01236
更新日期:2012-03-01 00:00:00
abstract::Spontaneous breathing trials (SBTs) are among the most commonly employed techniques to facilitate weaning from mechanical ventilation. The preferred SBT technique, however, is still unclear. To clarify the preferable SBT (T-piece or pressure support ventilation [PSV]), we conducted this systematic review. We then sear...
journal_title:Respiratory care
pub_type: 杂志文章,评审
doi:10.4187/respcare.04816
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Chronic hypoxemia in patients with COPD is a limiting factor that is associated with disease progression and significantly contributes to decreased physical activity. Although correction of hypoxemia results in physiological improvements, oxygen therapy may be related to social isolation and inactivity. Howe...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.06206
更新日期:2019-11-01 00:00:00
abstract::A 20-year-old man was admitted in the neurology ICU after the drainage of a large frontal hematoma related to the spontaneous bleeding of a recently diagnosed cavernoma. On admission the Glasgow coma score was 4/15, with evidence of sub-falcorial herniation and elevated intracranial pressure. On the 4th postoperative...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.01322
更新日期:2012-07-01 00:00:00
abstract::An 8-year-old female with pancreatic-insufficiency cystic fibrosis presented with recurrent pharyngitis, and reduction in body mass index and height velocity during the previous 2 years. Her symptoms (eg, snoring and restless sleep) suggested obstructive sleep apnea, and physical examination revealed tonsillar hypertr...
journal_title:Respiratory care
pub_type: 杂志文章
doi:
更新日期:2009-12-01 00:00:00
abstract::Aerosolized medications have been used for centuries to treat respiratory diseases. Until recently, inhalation therapy focused primarily on the treatment of asthma and chronic obstructive pulmonary disease, and the pressurized metered-dose inhaler was the delivery device of choice. However, the role of aerosol therapy...
journal_title:Respiratory care
pub_type: 杂志文章,评审
doi:
更新日期:2005-09-01 00:00:00
abstract::Endotracheal intubation can lead to iatrogenic trauma to the upper airways. Superficial mucosal tears in the mouth, pharynx, or larynx are common and can cause secondary infection and acute respiratory distress due to massive air leak. We report a patient who sustained a severe 5-cm tracheal laceration and subcutaneou...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.00891
更新日期:2011-06-01 00:00:00
abstract::As hospitals begin to implement electronic medical records, the inadequacies of legacy paper charting systems will become more evident. One area of particular concern for respiratory therapists is the charting of mechanical ventilator settings. Our profession's lack of a standardized and generally accepted taxonomy fo...
journal_title:Respiratory care
pub_type: 杂志文章
doi:
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:We previously reported the effects of high-flow nasal cannula (HFNC) oxygen therapy on thoraco-abdominal synchrony. This study was designed to clarify the effect of HFNC on thoraco-abdominal synchrony in pediatric subjects after cardiac surgery and to investigate HFNC optimal flow in this population. METHOD...
journal_title:Respiratory care
pub_type: 杂志文章,随机对照试验
doi:10.4187/respcare.06193
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Obstructive sleep apnea is a disorder characterized by recurrent obstruction of the upper airways during sleep. The high prevalence of this disease led to proposed new strategies based on the home evaluation and management of patients. OBJECTIVE:To compare home unattended portable monitoring and automatic C...
journal_title:Respiratory care
pub_type: 杂志文章,随机对照试验
doi:10.4187/respcare.01939
更新日期:2013-07-01 00:00:00
abstract:OBJECTIVE:To investigate the predictive value of the maximal inspiratory pressure obtained by a digital vacuometer using a unidirectional valve (P(ImaxUV)) as to weaning outcome, and to compare its performance with the respiratory drive using airway occlusion pressure at 0.1 second (P(0.1)), and P(0.1)/P(ImaxUV). METH...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.01489
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:Directed cough maneuvers are often included in physiotherapy management aimed at preventing postoperative pulmonary complications after open heart surgery, but there is little scientific evidence of the effectiveness of directed cough maneuvers. METHODS:We conducted a randomized intra-subject crossover tria...
journal_title:Respiratory care
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND:The benefits of contract learning have been identified in the literature as increased individualization to meet the student's individual needs, promotion of learner independence, and development of lifelong learning behaviors among students. METHODS:I used an "action research" approach to implement the cont...
journal_title:Respiratory care
pub_type: 杂志文章
doi:
更新日期:2008-11-01 00:00:00
abstract:BACKGROUND:Ventilation with low tidal volume is recommended for patients with acute lung injury. Current guidelines suggest limiting plateau pressure (Pplat) to < 30 cm H2O for septic patients needing mechanical ventilation. The aim of this study was to determine whether Pplat within the first 24 h of ICU admission is ...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.03138
更新日期:2015-01-01 00:00:00
abstract::The story of the development of oxygen and its role in mitigating the ravages of chronic stable hypoxemia have been fascinating. Today, over one million Americans receive home oxygen each day, usually for COPD, from one of the three available systems. The future requires less expensive, highly portable, and practical ...
journal_title:Respiratory care
pub_type: 历史文章,杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::Patient adherence with prescribed inhaled therapy is related to morbidity and mortality. The terms "compliance" and "adherence" are used in the literature to describe agreement between prescribed medication and patient practice, with "adherence" implying active patient participation. Patient adherence with inhaled med...
journal_title:Respiratory care
pub_type: 杂志文章,评审
doi:
更新日期:2005-10-01 00:00:00
abstract::Gorham syndrome is a rare disease that presents as progressive osteolysis, and may affect any part of the skeleton. The pathologic process involves the replacement of normal bone by aggressively expanding but non-neoplastic vascular tissue, resulting in massive osteolysis of the adjacent bone. If the spine and ribs ar...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.02355
更新日期:2013-11-01 00:00:00
abstract::Hospital-wide computerized information systems evolved from the need to capture patient information and perform billing and other financial functions. These systems, however, have fallen short of meeting the needs of respiratory care departments regarding work load assessment, productivity management, and the level of...
journal_title:Respiratory care
pub_type: 杂志文章,评审
doi:
更新日期:2004-04-01 00:00:00
abstract::Pulmonary rehabilitation (PR) is the standard of care for patients suffering chronic obstructive pulmonary disease (COPD). This report describes and defines PR and reviews the evidence regarding the efficacy of PR. COPD management guidelines that include PR have been published by the European Respiratory Society, the ...
journal_title:Respiratory care
pub_type: 杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:The value of impulse oscillometry (IOS) for bronchial provocation testing is poorly defined. We investigated the positive threshold derived from the parameters and diagnostic power of IOS for asthma with the leukotriene D(4) bronchial provocation test. METHODS:We enrolled 62 subjects with asthma and 21 heal...
journal_title:Respiratory care
pub_type: 杂志文章
doi:10.4187/respcare.02417
更新日期:2013-12-01 00:00:00
abstract::A computerized clinical information system (CIS) is potentially a very important information tool for research and improving health care processes as well as for optimizing data management and thereby minimizing health care costs. The newest CISs automatically collect patient data from various sources, including monit...
journal_title:Respiratory care
pub_type: 杂志文章
doi:
更新日期:2004-05-01 00:00:00