Hypoxemia during sleep in patients with chronic obstructive pulmonary disease: significance, detection, and effects of therapy.

Abstract:

:NOD is a common event in patients with symptomatic COPD who are not hypoxemic while awake. Up to 45% of these patients may have significant oxyhemoglobin desaturation during sleep, and most have evidence of pulmonary arterial hypertension. Although intuitively it would seem that supplemental oxygen during sleep should be of medical benefit in COPD patients with NOD, studies to data have not substantiated this idea. Medicare requirements for prescribing nocturnal oxygen are relatively liberal and there is the possibility of misuse, which would cause a substantial increase in the cost of home health care. A well designed multicenter study is needed to provide appropriate indications and guidelines for therapy in these patients.

journal_name

Respir Care

journal_title

Respiratory care

authors

O'Donohue WJ Jr,Bowman TJ

keywords:

subject

Has Abstract

pub_date

2000-02-01 00:00:00

pages

188-91; discussion 192-3

issue

2

eissn

0020-1324

issn

1943-3654

journal_volume

45

pub_type

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