Abstract：
:The physiologic effects of noninvasive ventilation (NIV) on work of breathing (WOB) and breathing pattern, respiratory-system mechanics, and hemodynamic function were examined via a literature review of clinical studies done between 1990 and 2008. Forty-one relevant studies were found; the majority examined patients with chronic obstructive pulmonary disease, whereas some also included patients with restrictive chest-wall disease or acute hypoxic respiratory failure. NIV reduced WOB in direct proportion to the level of inspiratory pressure-assist, and also by the ability of applied positive end-expiratory pressure (PEEP) to counter intrinsic PEEP. In general an inspiratory pressure-support level of 15 cm H(2)O and a PEEP of 5 cm H(2)O reduced most measures of WOB and inspiratory effort toward normal. When set to the same level of inspiratory pressure-assist, both pressure-support ventilation and proportional-assist ventilation effected comparable reductions in WOB. At high levels of inspiratory pressure-assist, NIV consistently increased dynamic lung compliance and tidal volume, and improved arterial blood gases. The hemodynamic effects of NIV are dependent upon the interplay between the type of mask, the level of inspiratory pressure-assist and PEEP, and the disease state. In general, patients with chronic obstructive pulmonary disease have a higher tendency toward decreased cardiac output at high levels of inspiratory pressure-assist, compared to those with acute lung injury.
journal_name
Respir Carejournal_title
Respiratory careauthors
Kallet RH,Diaz JVsubject
Has Abstractpub_date
2009-01-01 00:00:00pages
102-15issue
1eissn
0020-1324issn
1943-3654journal_volume
54pub_type
杂志文章相关文献
Respiratory Care文献大全abstract：:We present a patient with acute-onset dyspnea and unexplained severe hypoxemia. No signs of severe cardiopulmonary disease, pulmonary arterial hypertension, or pulmonary embolism were present. The patient was diagnosed with hepatopulmonary syndrome, since liver disease of alcoholic origin was present, markedly increa...
journal_title：Respiratory care
pub_type： 杂志文章
doi：10.4187/respcare.01612
更新日期：2012-11-01 00:00:00
abstract：BACKGROUND:The ventilatory ratio (VR) is a dead-space marker associated with mortality in mechanically ventilated adults with ARDS. The end-tidal alveolar dead space fraction (AVDSf) has been associated with mortality in children. However, AVDSf requires capnography measurements, whereas VR does not. We sought to exami...
journal_title：Respiratory care
pub_type： 杂志文章
doi：10.4187/respcare.07937
更新日期：2021-02-01 00:00:00
abstract：:We report the first successful use of venovenous extracorporeal membrane oxygenation (ECMO) for refractory respiratory failure in an infant with DiGeorge anomaly, following thymus transplantation. A 23-month-old female with complete immune-incompetent DiGeorge anomaly 65 days after allogenic thymus transplantation was...
journal_title：Respiratory care
pub_type： 杂志文章
doi：10.4187/respcare.01051
更新日期：2011-06-01 00:00:00
abstract：BACKGROUND:Ventilation with low tidal volume is recommended for patients with acute lung injury. Current guidelines suggest limiting plateau pressure (Pplat) to < 30 cm H2O for septic patients needing mechanical ventilation. The aim of this study was to determine whether Pplat within the first 24 h of ICU admission is ...
journal_title：Respiratory care
pub_type： 杂志文章
doi：10.4187/respcare.03138
更新日期：2015-01-01 00:00:00
abstract：:We describe a unique presentation of polymyositis-associated pneumonitis. A 45-year-old man with a history of polymyositis presented with an episode of fever, cough, dyspnea, rapidly progressive respiratory failure, and unilateral pulmonary infiltrates. Although bacterial pneumonia was initially suspected, all culture...
journal_title：Respiratory care
pub_type： 杂志文章
doi：
更新日期：2007-12-01 00:00:00
abstract：:In 2002 the National Asthma Education and Prevention Program published evidence-based guidelines for the diagnosis and management of asthma, but there are some unresolved asthma-management issues that need further research. For asthmatic children inhaled corticosteroids are more beneficial than as-needed use of beta(2...
journal_title：Respiratory care
pub_type： 杂志文章,评审
doi：
更新日期：2004-07-01 00:00:00
abstract：BACKGROUND:High-flow nasal cannula (HFNC) is commonly being used to provide noninvasive respiratory support in newborn infants. Continuous distending pressure generated by these devices in preterm infants has not been elucidated. The aim of this work was to determine the association between HFNC flow in L/min and end-e...
journal_title：Respiratory care
pub_type： 杂志文章
doi：10.4187/respcare.04317
更新日期：2016-03-01 00:00:00
abstract：:Sialorrhea or drooling represents quite a common problem in patients with amyotrophic lateral sclerosis (ALS). In this review, we describe the possible treatments for this issue. Current medical management is not always effective: anticholinergic drugs (atropine, glycopyrrolate, amitriptyline, hyoscyamine, and transde...
journal_title：Respiratory care
pub_type： 杂志文章,评审
doi：10.4187/respcare.02856
更新日期：2015-03-01 00:00:00
abstract：BACKGROUND:Current literature has been inconsistent in demonstrating that minimizing the duration of mechanical ventilation in very-low-birth-weight (VLBW) newborns reduces lung damage. OBJECTIVE:To determine if introduction of bubble nasal CPAP (bnCPAP), early surfactant treatment, and rapid extubation (combined bnCP...
journal_title：Respiratory care
pub_type： 杂志文章
doi：10.4187/respcare.01998
更新日期：2013-07-01 00:00:00
abstract：BACKGROUND:Nebulizers are a popular means of delivering aerosolized medication, primarily albuterol, to the bronchial airways of patients, and there has been extensive research done on numerous nebulizers used with nebulizer T-pieces and corrugated tubing. Very little research has been performed on other types of nebul...
journal_title：Respiratory care
pub_type： 杂志文章
doi：
更新日期：2000-03-01 00:00:00
abstract：BACKGROUND:In patients with kyphoscoliosis, long-term mechanical ventilation improves chronic alveolar hypoventilation during spontaneous breathing, improves quality of life, decreases the need for hospitalization, and improves survival. In these patients respiratory infection can precipitate acute respiratory failure ...
journal_title：Respiratory care
pub_type： 杂志文章
doi：
更新日期：2007-06-01 00:00:00
abstract：OBJECTIVE:To determine whether outcomes (mortality and need for intensive care unit [ICU] readmission) of patients undergoing tracheostomy in the ICU can be predicted by common clinical or historical criteria. METHODS:We conducted a retrospective review of data from the medical record and Project Impact database in a ...
journal_title：Respiratory care
pub_type： 杂志文章
doi：
更新日期：2009-12-01 00:00:00
abstract：BACKGROUND:Predicting mortality has become a necessary step for selecting patients for clinical trials and defining outcomes. We examined whether stratification by tertiles of respiratory and ventilatory variables at the onset of acute respiratory distress syndrome (ARDS) identifies patients with different risks of dea...
journal_title：Respiratory care
pub_type： 杂志文章,多中心研究
doi：10.4187/respcare.00811
更新日期：2011-04-01 00:00:00
abstract：:It should be recognized that the advent of LTOT created a new health care system that is based on powerful scientific data. Oxygen therapy studies such as those by the Nocturnal Oxygen Therapy Trial Group and the British Medical Research Council study clearly demonstrated that LTOT improves both the length and quality...
journal_title：Respiratory care
pub_type： 共识发展会议,杂志文章,评审
doi：
更新日期：2000-08-01 00:00:00
abstract：:Dieulafoy disease of the bronchus is a rare condition. A 28-y-old male patient with recurrent exacerbations of hemoptysis (producing up to 300 mL) over the previous 4 y was admitted to our hospital following an acute episode. A 3-mm sessile lesion covered with somewhat ulcerated smooth mucosa was detected at the dista...
journal_title：Respiratory care
pub_type： 杂志文章
doi：10.4187/respcare.03307
更新日期：2015-01-01 00:00:00
abstract：BACKGROUND:Treatment of bronchiectasis includes drugs, oxygen therapy, and bronchial-clearance maneuvers. OBJECTIVE:To assess the safety and efficacy of intrapulmonary percussive ventilation (IPV) compared to traditional standard chest physical therapy in patients with bronchiectasis and productive cough. METHODS:In ...
journal_title：Respiratory care
pub_type： 杂志文章,随机对照试验
doi：10.4187/respcare.01098
更新日期：2011-07-01 00:00:00
abstract：:We describe the case of a woman who presented to the intensive care unit with acute respiratory failure that required mechanical ventilation. She had severe pulmonary hypertension secondary to interstitial lung disease, and her history included sarcoidosis and tuberculosis. She was dependent on inhaled nitric oxide (...
journal_title：Respiratory care
pub_type： 杂志文章
doi：10.4187/respcare.01147
更新日期：2011-10-01 00:00:00
abstract：BACKGROUND:Extracorporeal membrane oxygenation (ECMO) is often used in patients with severe respiratory failure to improve oxygenation and survival. ECMO gives the lungs an opportunity to rest and recover. The addition of prone positioning therapy used concurrently with ECMO can further aid in optimizing alveolar recru...
journal_title：Respiratory care
pub_type： 杂志文章,评审
doi：10.4187/respcare.03882
更新日期：2016-02-01 00:00:00
abstract：BACKGROUND:The utilization of noninvasive ventilation (NIV) in the Veterans Affairs health-care system is not well characterized. A survey of physicians and respiratory therapists was conducted to better understand its use. METHODS:Three hospitals in each of 21 Veterans Affairs networks were selected based on severity...
journal_title：Respiratory care
pub_type： 杂志文章
doi：
更新日期：2009-10-01 00:00:00
abstract：:As the basis for this paper, it must be acknowledged that children are not simply small adults. But this acknowledgment must go further: infants are not simply small adolescents. As data for pediatric mechanical ventilation, in general, and the management for pediatric acute lung injury, more specifically, are very l...
journal_title：Respiratory care
pub_type： 杂志文章,评审
doi：10.4187/respcare.01413
更新日期：2011-09-01 00:00:00
abstract：BACKGROUND:The use of neurally-adjusted ventilatory assist (NAVA) during noninvasive ventilation (NIV) results in better patient-ventilator interaction. Whether this improves clinical outcomes lacks dedicated study. METHODS:In this randomized controlled trial, we compared NAVA with PSV for delivering NIV in consecutiv...
journal_title：Respiratory care
pub_type： 杂志文章
doi：10.4187/respcare.07952
更新日期：2021-02-01 00:00:00
abstract：:Acute brain injury, in the form of trauma, stroke, or spontaneous hemorrhage, occurs commonly and in all age groups. Although the management of these conditions differs considerably, certain physiologic principles are shared by all and are useful in guiding the management of the most severely injured patients. This ar...
journal_title：Respiratory care
pub_type： 杂志文章
doi：
更新日期：2006-04-01 00:00:00
abstract：:Pulmonary rehabilitation has emerged as a standard of care for patients with chronic lung disease, based on a growing body of scientific evidence. Over recent decades, several organizations have championed pulmonary rehabilitation and developed comprehensive statements, practice guidelines, and evidence-based guidelin...
journal_title：Respiratory care
pub_type： 杂志文章,评审
doi：
更新日期：2008-09-01 00:00:00
abstract：:Oxygen is a colorless, odorless, tasteless gas that is utilized by the body for respiration. Oxygen has played a major role in respiratory care. Oxygen therapy is useful in treating hypoxemia but is often thought of as a benign therapy. After many years of study, we have learned a great deal of the benefits and potent...
journal_title：Respiratory care
pub_type： 杂志文章,评审
doi：10.4187/respcare.05245
更新日期：2017-06-01 00:00:00
abstract：:CPAP is a spontaneous mode of ventilation that maintains a constant airway pressure during the inspiratory and expiratory phases. This therapeutic modality is used across the continuum of care from pre-hospital treatment to intensive and acute care units to the home care environment to treat a host of acute and chroni...
journal_title：Respiratory care
pub_type： 杂志文章,评审
doi：10.4187/respcare.06625
更新日期：2019-06-01 00:00:00
abstract：OBJECTIVE:Evaluate the effects of continuous positive airway pressure (CPAP)/positive end-expiratory pressure (PEEP) and pressure support ventilation (PSV) on work of breathing (WOB). METHODS:With 13 anesthetized lambs we measured WOB with an esophageal balloon and flow signals. All the animals were sedated, intubated...
journal_title：Respiratory care
pub_type： 杂志文章
doi：
更新日期：2003-07-01 00:00:00
abstract：:Mechanical ventilation incurs substantial morbidity, mortality, and costs. Both premature extubation and delayed extubation can cause harm. Therefore, weaning that is both expeditious and safe is highly desirable. The purpose of this review is to summarize the literature related to weaning modes, spontaneous breathing...
journal_title：Respiratory care
pub_type： 杂志文章,评审
doi：
更新日期：2001-12-01 00:00:00
abstract：:NOD is a common event in patients with symptomatic COPD who are not hypoxemic while awake. Up to 45% of these patients may have significant oxyhemoglobin desaturation during sleep, and most have evidence of pulmonary arterial hypertension. Although intuitively it would seem that supplemental oxygen during sleep should...
journal_title：Respiratory care
pub_type： 杂志文章,评审
doi：
更新日期：2000-02-01 00:00:00
abstract：BACKGROUND:Because of our concern for the safety of bedside caregivers who care for infants receiving ribavirin for long periods of time each day for many days, we evaluated the effectiveness of a double-tent enclosure with vacuum scavengers during simulated and actual patient administration. MATERIALS & METHODS:Part ...
journal_title：Respiratory care
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：:The estimation of pleural pressure with esophageal manometry has been used for decades, and it has been a fertile area of physiology research in healthy subject as well as during mechanical ventilation in patients with lung injury. However, its scarce adoption in clinical practice takes its roots from the (false) idea...
journal_title：Respiratory care
pub_type： 杂志文章,评审
doi：10.4187/respcare.07425
更新日期：2020-06-01 00:00:00
