Successful extracorporeal membrane oxygenation for respiratory failure in an infant with DiGeorge anomaly, following thymus transplantation.

Abstract:

:We report the first successful use of venovenous extracorporeal membrane oxygenation (ECMO) for refractory respiratory failure in an infant with DiGeorge anomaly, following thymus transplantation. A 23-month-old female with complete immune-incompetent DiGeorge anomaly 65 days after allogenic thymus transplantation was treated in our pediatric intensive care unit for acute respiratory failure secondary to bacterial sepsis. She subsequently developed acute hypercarbic respiratory failure unresponsive to conventional medical therapy. She was successfully managed with venovenous ECMO for 4 days, with complete resolution of her respiratory symptoms. This case demonstrates the complex decision making process regarding initiation of ECMO in patients with severe immunodeficiency.

journal_name

Respir Care

journal_title

Respiratory care

authors

Hornik CP,Hartman ME,Markert ML,Lodge AJ,Cheifetz IM,Turner DA

doi

10.4187/respcare.01051

subject

Has Abstract

pub_date

2011-06-01 00:00:00

pages

866-70

issue

6

eissn

0020-1324

issn

1943-3654

pii

rc01051r2hornik

journal_volume

56

pub_type

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