Long-term survival in patients with tracheostomy and prolonged mechanical ventilation in Olmsted County, Minnesota.

Abstract:

BACKGROUND:An increasing number of patients require prolonged mechanical ventilation (PMV), which is associated with high morbidity and poor long-term survival, but there are few data regarding the incidence and outcome of PMV patients from a community perspective. METHODS:We retrospectively reviewed the electronic medical records of adult Olmsted county, Minnesota, residents admitted to the intensive care units at the 2 Mayo Clinic Rochester hospitals from January 1, 2003, to December 31, 2007, who underwent tracheostomy for PMV. RESULTS:Sixty-five patients, median age 68 years (interquartile range [IQR] 49-80 y), 39 male, underwent tracheostomy for PMV, resulting in an age-adjusted incidence of 13 (95% CI 10-17) per 100,000 patient-years at risk. The median number of days on mechanical ventilation was 24 days (IQR 18-37 d). Forty-six patients (71%) survived to hospital discharge, and 36 (55%) were alive at 1-year follow-up. After adjusting for age and baseline severity of illness, the presence of COPD was independently associated with 1-year mortality (hazard ratio 3.4, 95% CI 1.4-8.2%). CONCLUSIONS:There was a considerable incidence of tracheostomy for PMV. The presence of COPD was an independent predictor of 1-year mortality.

journal_name

Respir Care

journal_title

Respiratory care

authors

Kojicic M,Li G,Ahmed A,Thakur L,Trillo-Alvarez C,Cartin-Ceba R,Gay PC,Gajic O

doi

10.4187/respcare.01096

subject

Has Abstract

pub_date

2011-11-01 00:00:00

pages

1765-70

issue

11

eissn

0020-1324

issn

1943-3654

pii

rc01096r2kojicic

journal_volume

56

pub_type

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