Hepatitis C virus infection and health-related quality of life.

abstract：AIM:To explore the role of heat shock protein-90 (HSP-90) for nitrergic vasorelaxation in the splanchnic circulation in rats with and without portal hypertension. METHODS:Neuronal nitric oxide synthase (nNOS) and HSP-90 were analyzed by immunofluorescence, western blotting and co-immunoprecipitation in the mesenteric ...

journal_title：World journal of gastroenterology

authors： Moleda L,Jurzik L,Froh M,Gäbele E,Hellerbrand C,Straub RH,Schölmerich J,Wiest R

更新日期：2010-04-21 00:00:00

abstract：AIM:To investigate the therapeutic effects of mesenchymal stem cells (MSCs) transplanted intraperitoneally and intravenously in a murine model of colitis. METHODS:MSCs were isolated from C57BL/6 mouse adipose tissue. MSC cultures were analyzed according to morphology, cellular differentiation potential, and surface mo...

journal_title：World journal of gastroenterology

authors： Gonçalves Fda C,Schneider N,Pinto FO,Meyer FS,Visioli F,Pfaffenseller B,Lopez PL,Passos EP,Cirne-Lima EO,Meurer L,Paz AH

更新日期：2014-12-28 00:00:00

abstract：AIM:To investigate the ultrastructure of oval cells in children with chronic hepatitis B, with special emphasis on their location in areas of collagen fibroplasia. METHODS:Morphological investigations were conducted on biopsy material obtained from 40 children, aged 3-16 years with chronic hepatitis B. The stage of fi...

journal_title：World journal of gastroenterology

authors： Sobaniec-Lotowska ME,Lotowska JM,Lebensztejn DM

更新日期：2007-06-07 00:00:00

abstract：AIM:To compare the antisecretory activity and plasma drug concentrations of a single oral dose of 10 mg lafutidine, a novel H2 receptor antagonist, with those of the proton pump inhibitor lansoprazole (LPZ) 30 mg. METHODS:Ten volunteers without H pylori infection participated in this crossover study comparing lafutidi...

journal_title：World journal of gastroenterology

authors： Yamagishi H,Koike T,Ohara S,Horii T,Kikuchi R,Kobayashi S,Abe Y,Iijima K,Imatani A,Suzuki K,Hishinuma T,Goto J,Shimosegawa T

更新日期：2008-04-21 00:00:00

abstract：AIM:To evaluate the positive predictive value of abdominal non-prepared computed tomography (CT) for diagnosing intestinal lumen or wall lesions in patients presenting to the emergency room (ER) with abdominal complaints. METHODS:For 1-year we prospectively evaluated all ER patients hospitalized after abdominal CT sca...

journal_title：World journal of gastroenterology

authors： Mizrahi M,Mintz Y,Rivkind A,Kisselgoff D,Libson E,Brezis M,Goldin E,Shibolet O

更新日期：2005-04-07 00:00:00

abstract：AIM:To investigate the rate of spontaneous passage of single and symptomatic common bile duct (CBD) stones ≤ 10 mm in diameter in 4 wk with or without a 2-wk course of anisodamine. METHODS:A multicenter, randomized, placebo-controlled trial was undertaken. A total of 197 patients who met the inclusion criteria were en...

journal_title：World journal of gastroenterology

authors： Gao J,Ding XM,Ke S,Zhou YM,Qian XJ,Ma RL,Ning CM,Xin ZH,Sun WB

更新日期：2013-10-21 00:00:00

abstract：AIM:To investigate expression of microRNA (miRNA) and potential targets in chemotherapy resistant esophageal cancer cell lines. METHODS:An in-vitro model of acquired chemotherapy resistance in esophageal adeno- (EAC) and squamous cell carcinoma (ESCC) cells was used, and microRNA expression profiles for cisplatin or 5...

journal_title：World journal of gastroenterology

authors： Hummel R,Sie C,Watson DI,Wang T,Ansar A,Michael MZ,Van der Hoek M,Haier J,Hussey DJ

更新日期：2014-10-28 00:00:00

abstract：:Although spinal tumors are uncommon, they may reduce survival or cause serious functional disorders in the extremities. Metastatic spinal tumors from malignant tumors can induce symptoms of spinal cord compression, such as paraplegia, quadriplegia, and vesicorectal disturbance, which are aggravated with progression of...

journal_title：World journal of gastroenterology

authors： Tamaki K,Shimizu I,Urata M,Kohno N,Fukuno H,Ito S,Sano N

更新日期：2007-05-21 00:00:00

abstract：AIM:Because of a major resistance to chemotherapy, prognosis of hepatocellular carcinoma (HCC) is still poor. New treatments are required and gene therapy may be an option. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis in multiple malignant tumors, and using adenoviral vectors has sh...

journal_title：World journal of gastroenterology

authors： Jacob D,Schumacher G,Bahra M,Davis J,Zhu HB,Zhang LD,Teraishi F,Neuhaus P,Fang BL

更新日期：2005-05-07 00:00:00

abstract：AIM:To investigate the influence of experimental obstructive jaundice and exogenous bombesin (BBS) and neurotensin (NT) administration on the expression of the tight junction (TJ)-protein claudin-4 in intestinal epithelium of rats. METHODS:Forty male Wistar rats were randomly divided into five groups: I = controls, II...

journal_title：World journal of gastroenterology

authors： Assimakopoulos SF,Vagianos CE,Charonis AS,Alexandris IH,Spiliopoulou I,Thomopoulos KC,Nikolopoulou VN,Scopa CD

更新日期：2006-06-07 00:00:00

abstract：AIM:To analyze the association between Helicobacter spp. and some common gut bacteria in patients with cholecystitis. METHODS:A nested-polymerase chain reaction (PCR), specific to 16S rRNA of Helicobacter spp. was performed on paraffin-embedded gallbladder samples of 100 cholecystitis and 102 control cases. The sample...

journal_title：World journal of gastroenterology

authors： Karagin PH,Stenram U,Wadström T,Ljungh A

更新日期：2010-10-14 00:00:00

abstract：:More than five years ago, the treatment of hepatitis C virus infection was revolutionized with the introduction of all-oral direct-acting antiviral (DAA) drugs. They proved highly efficient in curing patients with chronic hepatitis C (CHC), including patients with cirrhosis. The new DAA treatments were alleged to indu...

journal_title：World journal of gastroenterology

authors： Laursen TL,Sandahl TD,Kazankov K,George J,Grønbæk H

更新日期：2020-06-14 00:00:00

abstract：:Ischemic bowel disease results from an acute or chronic drop in the blood supply to the bowel and may have various clinical presentations, such as intestinal angina, ischemic colitis or intestinal infarction. Elderly patients with systemic atherosclerosis who are symptomatic for the disease in two or more vascular bed...

journal_title：World journal of gastroenterology

authors： Georgescu EF,Carstea D,Dumitrescu D,Teodorescu R,Carstea A

更新日期：2012-10-21 00:00:00

abstract：:To review the underlying pathophysiology and currently available treatments for pruritis associated with jaundice. English language literature was reviewed using MEDLINE, PubMed, EMBASE and clinicaltrials.gov for papers and trails addressing the pathophysiology and potential treatments for pruritis associated with jau...

journal_title：World journal of gastroenterology

authors： Bassari R,Koea JB

更新日期：2015-02-07 00:00:00

abstract：AIM:To investigate whether potent acid inhibition is effective in non-erosive reflux disease (NERD) refractory to standard rabeprazole (RPZ) treatment. METHODS:We treated 10 Japanese patients with NERD resistant to standard dosages of RPZ: 10 mg or 20 mg od, 20 mg bid, or 10 mg qid for 14 d. All patients completed a f...

journal_title：World journal of gastroenterology

authors： Sugimoto M,Nishino M,Kodaira C,Yamade M,Uotani T,Ikuma M,Umemura K,Furuta T

更新日期：2011-04-14 00:00:00

abstract：AIM:To compare the hemostatic efficacy and safety of two mechanical endoscopic methods: endoscopic band ligation (EBL) and endoscopic hemoclip placement (EHP) in patients with actively bleeding Mallory-Weiss syndrome (MWS). METHODS:A prospective randomized study to compare the efficacy and safety of EHP with EBL was p...

journal_title：World journal of gastroenterology

authors： Cho YS,Chae HS,Kim HK,Kim JS,Kim BW,Kim SS,Han SW,Choi KY

更新日期：2008-04-07 00:00:00

abstract：AIM:To determine whether efflux systems contribute to multidrug resistance of H pylori. METHODS:A chloramphenicol-induced multidrug resistance model of six susceptible H pylori strains (5 isolates and H pylori NCTC11637) was developed. Multidrug-resistant (MDR) strains were selected and the minimal inhibitory concentr...

journal_title：World journal of gastroenterology

authors： Liu ZQ,Zheng PY,Yang PC

更新日期：2008-09-07 00:00:00

abstract：AIM:To establish a quantitative method to measure the amount of lipids. METHODS:The livers of 53 male Wistar rats (225 g) with different degrees of hepatic steatosis were studied. This model of hepatic steatosis was based on a high carbohydrate, fat-free modified diet. Biopsies were classified into four grades dependi...

journal_title：World journal of gastroenterology

authors： Hijona E,Hijona L,Larzabal M,Sarasqueta C,Aldazabal P,Arenas J,Bujanda L

更新日期：2010-03-28 00:00:00

abstract：AIM:To evaluate the risk factors-other than nonsteroidal anti-inflammatory drugs-for colonic diverticular bleeding in a westernized population. METHODS:One hundred and forty patients, treated for symptomatic diverticular disease in a community based hospital, were included. Thirty (21%) had signs of diverticular bleed...

journal_title：World journal of gastroenterology

authors： Jansen A,Harenberg S,Grenda U,Elsing C

更新日期：2009-01-28 00:00:00

abstract：BACKGROUND:Public awareness of colorectal cancer (CRC) and uptake of CRC screening remain challenges. The viewpoints of the target population (asymptomatic individuals older than 50) regarding CRC screening information sources and the reasons for and against participation in CRC screening are not well known in the Czec...

journal_title：World journal of gastroenterology

authors： Kroupa R,Ondrackova M,Kovalcikova P,Dastych M,Pavlik T,Kunovsky L,Dolina J

更新日期：2019-03-07 00:00:00

abstract：:Chronic pancreatitis (CP) continues to be a clinical challenge. Persistent or recurrent abdominal pain is the most compelling symptom that drives patients to seek medical care. Unfortunately, in spite of using several treatment approaches in the clinical setting, there is no single specific treatment modality that can...

journal_title：World journal of gastroenterology

authors： Talukdar R,Reddy DN

更新日期：2013-10-14 00:00:00

abstract：:Colonic motility subserves large bowel functions, including absorption, storage, propulsion and defaecation. Colonic motor dysfunction remains the leading hypothesis to explain symptom generation in chronic constipation, a heterogeneous condition which is extremely prevalent in the general population, and has huge soc...

journal_title：World journal of gastroenterology

authors： Dinning PG,Benninga MA,Southwell BR,Scott SM

更新日期：2010-11-07 00:00:00

abstract：AIM:To evaluate the efficacy and safety of grasper type scissors (GTS) for endoscopic submucosal dissection (ESD) of gastric epithelial neoplasia. METHODS:The study was performed by 4 endoscopists in 4 institutions affiliated to The Catholic University of Korea. ESD was performed in 76 consecutive patients with gastri...

journal_title：World journal of gastroenterology

authors： Chung WC,Kim BW,Lim CH,Kim TH,Park JM,Kim JS

更新日期：2013-10-07 00:00:00

abstract：AIM:To investigate markers for high-grade dysplasia for the optimal timing of liver transplantation in patients with primary sclerosing cholangitis (PSC). METHODS:Earlier data support a dysplasia-carcinoma sequence, even low- to high-grade dysplasia, in PSC-associated cholangiocarcinoma (CCA). Surveillance using endos...

journal_title：World journal of gastroenterology

authors： Boyd S,Vannas M,Jokelainen K,Isoniemi H,Mäkisalo H,Färkkilä MA,Arola J

更新日期：2017-09-07 00:00:00

abstract：:The combination of either boceprevir or telaprevir with ribavirin and interferon (triple therapy) has been shown to be more effective than ribavirin+interferon (dual therapy) for the treatment of genotype 1 hepatitis C. Since the benefit of these treatments takes place after years, simulation models are needed to pred...

journal_title：World journal of gastroenterology

authors： Messori A,Fadda V,Maratea D,Trippoli S

更新日期：2012-06-21 00:00:00

abstract：AIM:To analyze the effect of intralesional steroid injections in addition to endoscopic dilation of benign refractory esophageal strictures. METHODS:A comprehensive search was performed in three databases from inception to 10 April 2017 to identify trials, comparing the efficacy of endoscopic dilation to dilation comb...

journal_title：World journal of gastroenterology

authors： Szapáry L,Tinusz B,Farkas N,Márta K,Szakó L,Meczker Á,Hágendorn R,Bajor J,Vincze Á,Gyöngyi Z,Mikó A,Csupor D,Hegyi P,Erőss B

更新日期：2018-06-07 00:00:00

abstract：:Sorafenib is the current standard treatment for advanced hepatocellular carcinoma (HCC), but its efficacy is modest with low response rates and short response duration. Predictive biomarkers for sorafenib efficacy are necessary. However, efforts to determine biomarkers for sorafenib have led only to potential candidat...

journal_title：World journal of gastroenterology

authors： Shao YY,Hsu CH,Cheng AL

更新日期：2015-09-28 00:00:00

abstract：:Mastocytosis is a clonal neoplastic disorder of the mast cells (MC) that can be limited to the skin (cutaneous mastocytosis) or involve one or more extracutaneous organs (systemic mastocytosis). The clinical manifestations of mastocytosis are heterogeneous ranging from indolent disease with a long-term survival to a h...

journal_title：World journal of gastroenterology

authors： Martins C,Teixeira C,Ribeiro S,Trabulo D,Cardoso C,Mangualde J,Freire R,Gamito É,Alves AL,Cremers I,Alves C,Neves A,Oliveira AP

更新日期：2016-07-28 00:00:00

abstract：AIM:To evaluate the clinical characteristics of nonvariceal upper gastrointestinal hemorrhage (NGIH) in patients with chronic kidney disease (CKD). METHODS:From 2003 to 2010, a total of 72 CKD patients (male n = 52, 72.2%; female n = 20, 27.8%) who had undergone endoscopic treatments for NGIH were retrospectively iden...

journal_title：World journal of gastroenterology

authors： Bang CS,Lee YS,Lee YH,Sung H,Park HJ,Kim HS,Kim JB,Baik GH,Kim YS,Yoon JH,Kim DJ,Suk KT

更新日期：2013-11-21 00:00:00

abstract：AIM:To study the protective effect of Astragalus membranaceus on intestinal mucosa reperfusion injury and its mechanism after hemorrhagic shock in rats. METHODS:A total of 32 SD rats were randomly divided into four groups (n = 8, each group): normal group, model group, low dosage group (treated with 10 g/kg Astragalus...

journal_title：World journal of gastroenterology

authors： Hei ZQ,Huang HQ,Zhang JJ,Chen BX,Li XY

更新日期：2005-08-28 00:00:00