Pervasive developmental disorders in children of hyperandrogenic women with polycystic ovary syndrome: a longitudinal case-control study.

abstract：OBJECTIVE:Abdominal visceral (VAT) and subcutaneous (SAT) adipose tissues contribute to obesity, but may have different cardiometabolic risk profiles. We examined and compared the associations of abdominal VAT and SAT with metabolic risk factors in a large cohort of Chinese adults. METHODS:This study was based on cros...

journal_title：Clinical endocrinology

authors： Tang L,Zhang F,Tong N

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:Thyroid dysfunction and obesity during pregnancy have been associated with negative neonatal and obstetric outcomes. Thyroid hormone reference ranges have not been established for the pregnant Hispanic population. This study defines thyroid hormone reference ranges during early pregnancy in Chilean women and ...

journal_title：Clinical endocrinology

authors： Mosso L,Martínez A,Rojas MP,Latorre G,Margozzini P,Lyng T,Carvajal J,Campusano C,Arteaga E,Boucai L

更新日期：2016-12-01 00:00:00

abstract：:In a prospective controlled trial we investigated the effect of an induction dose of etomidate (0.26 mg/kg i.v.) on plasma ACTH, progesterone, 17 alpha OH-progesterone, 11-deoxycortisol, cortisol, cortisone, corticosterone, 11-deoxycorticosterone, and aldosterone in seven males undergoing general anaesthesia. Seven ot...

journal_title：Clinical endocrinology

authors： Allolio B,Dörr H,Stuttmann R,Knorr D,Engelhardt D,Winkelmann W

更新日期：1985-03-01 00:00:00

abstract：OBJECTIVE:To compare the relative utility of GH secretion via pharmacological stimulation, overnight serial sampling, IGF-I levels and auxological variables as predictors of change in height standard deviation score (deltaHt SDS) during GH treatment. DESIGN:A multicentre observational study. PATIENTS:Prepubertal chil...

journal_title：Clinical endocrinology

authors： Rogol AD,Blethen SL,Sy JP,Veldhuis JD

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVE:We explored the possibility of a genetic anomaly in the sex determining region of the Y chromosome, SRY gene, known to be equated to the testis determining region. PATIENTS:Four patients with bilateral congenital anorchia, absence of testicular tissue, elevated FSH and a lack of testosterone response to huma...

journal_title：Clinical endocrinology

authors： Lobaccaro JM,Medlej R,Berta P,Belon C,Galifer RB,Guthmann JP,Chevalier C,Czernichow P,Dumas R,Sultan C

更新日期：1993-02-01 00:00:00

abstract：OBJECTIVE:To compare effectiveness and tolerability of quinagolide (CV 205-502) and cabergoline (CAB) treatments in 39 patients with prolactinoma. STUDY DESIGN:All 39 patients were treated first with quinagolide for 12 months and then with cabergoline for 12 months. A wash-out period was performed in all patients afte...

journal_title：Clinical endocrinology

authors： Di Sarno A,Landi ML,Marzullo P,Di Somma C,Pivonello R,Cerbone G,Lombardi G,Colao A

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVES:We postulated the mechanism for the association between angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and insulin sensitivity might relate to changes in blood flow regulation. We studied the association of this polymorphism with insulin action, and insulin-mediated changes in...

journal_title：Clinical endocrinology

authors： Foo M,Coppack SW,Denver AE,Bulmer K,Yudkin JS

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Adrenal vein sampling (AVS) failure is mainly due to right adrenal vein unavailability. Multinomial regression modelling (MRM) and left adrenal vein-to-peripheral vein ratio (LAV/PV) were proposed to predict the lateralization index without the right AVS. OBJECTIVE:To assess external validity of MRM and LAV...

journal_title：Clinical endocrinology

authors： Bouchard-Bellavance R,Perrault F,Soulez G,Chagnon M,Kline GA,Bourdeau I,Lacroix A,So B,Therasse E

更新日期：2020-12-01 00:00:00

abstract：:Long-term bromocriptine treatment was discontinued in thirty-seven women with hyperprolactinaemic amenorrhoea. After cessation of therapy thirty of the thirty-seven women became hyperprolactinaemic again with amenorrhoea or anovulatory bleeding. Seven of the women continued to have regular ovulatory menstruation but o...

journal_title：Clinical endocrinology

authors： Bergh T,Nillius SJ,Wide L

更新日期：1982-06-01 00:00:00

abstract：OBJECTIVE:Abnormalities in the hypothalamic-pituitary-thyroid (HPT) axis have been implicated in Prader-Willi syndrome (PWS); however, limited information is currently available on age-dependent alterations in the HPT axis. We herein investigated age-dependent differences in thyroid hormone levels in PWS children. DES...

journal_title：Clinical endocrinology

authors： Konishi A,Ida S,Shoji Y,Etani Y,Kawai M

更新日期：2020-08-31 00:00:00

abstract：OBJECTIVE:Circulating testosterone declines during male ageing, and low testosterone may predispose to ill health. We sought to determine whether greater participation in healthy behaviours predicted reduced risk of subsequent lower circulating testosterone in older men. DESIGN:Cross-sectional analysis of a population...

journal_title：Clinical endocrinology

authors： Yeap BB,Almeida OP,Hyde Z,Norman PE,Chubb SA,Jamrozik K,Hankey GJ,Flicker L

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:Our clinical practice has been to offer treatment with cyclical disodium etidronate and high dose calcium supplements (1500-1600 mg/day) to all female patients with osteoporosis who are unable or unwilling to take hormone replacement therapy (HRT), and male osteoporotics. In a retrospective study we compared ...

journal_title：Clinical endocrinology

authors： Orme SM,Simpson M,Stewart SP,Oldroyd B,Westmacott CF,Smith MA,Belchetz PE

更新日期：1994-08-01 00:00:00

abstract：OBJECTIVE:Obesity is characterized by hyperleptinaemia, which is associated with diabetes, hypertension and coronary heart disease. The aim of this study was to determine if body fat and muscle measures predict the natural increase in leptin over 2·6 years in older adults. METHODS:A total of 190 subjects (50% females)...

journal_title：Clinical endocrinology

authors： Antony B,Jones G,Stannus O,Blizzard L,Ding C

更新日期：2013-11-01 00:00:00

abstract：:To test whether the administration of sodium fluoride in vivo results in an increase in osteocalcin concentration, we administered sodium fluoride to seven healthy male subjects for a period of 3 weeks. Fasting calcium, phosphate, alkaline phosphatase, 25-hydroxyvitamin D, parathyroid hormone and osteocalcin were meas...

journal_title：Clinical endocrinology

authors： Dandona P,Coumar A,Gill DS,Bell J,Thomas M

更新日期：1988-10-01 00:00:00

abstract：INTRODUCTION:  Surgical remission rates for acromegaly vary and are dependent on the tumour morphology, biochemical definition of disease remission and surgical expertise. A previous report from the Manchester region in 1998 reported an overall surgical remission rate of 27% using accepted criteria for biochemical remi...

journal_title：Clinical endocrinology

authors： Wang YY,Higham C,Kearney T,Davis JR,Trainer P,Gnanalingham KK

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Increased frequencies of adrenal tumours and testicular adrenal rest tumours (TART) have been reported in patients with 21-hydroxylase deficiency (21OHD). OBJECTIVE:Patients, methods and design From a cross-sectional population-based study of 101 adult Norwegian patients with 21OHD, sixty-two participated i...

journal_title：Clinical endocrinology

authors： Nermoen I,Rørvik J,Holmedal SH,Hykkerud DL,Fougner KJ,Svartberg J,Husebye ES,Løvås K

更新日期：2011-12-01 00:00:00

abstract：:A 39-year-old woman presented with secondary amenorrhoea in the absence of galactorrhoea, hirsutism or virilization. Investigation revealed a strikingly elevated serum testosterone, dihydrotesterone, free testosterone and LH level. At laparotomy a large granulosa cell tumour was encountered and totally removed. Analys...

journal_title：Clinical endocrinology

authors： Taylor HC,Velasco ME,Flores SG,Berg G,Brown TR

更新日期：1982-12-01 00:00:00

abstract：:The ratios of reverse triiodothyronine (rT3) to triiodothyronine (T3) concentrations were similar (0.89 +/- 0.09) in twenty-three autonomous thyroid nodules (fourteen decompensated, nine compensated) and paranodular tissues (0.82 +/- 0.08), whereas the serum ratio was significantly lower (0.098 +/- 0.014). This is com...

journal_title：Clinical endocrinology

authors： Reinwein D,Durrer H,Emrich D,Meinhold H,Wenzel KW

更新日期：1977-08-01 00:00:00

abstract：OBJECTIVE:Non-tumour causes of hyperprolactinaemia, including prolactin-elevating drugs, must be excluded. There is a general view that such drugs are unlikely to raise serum PRL above 3000 mU/I, but the literature is confusing. We report 8 patients receiving treatment with neuroleptic drugs, whose serum PRL concentrat...

journal_title：Clinical endocrinology

authors： Pollock A,McLaren EH

更新日期：1998-10-01 00:00:00

abstract：:In order to evaluate simultaneously in thyrotoxic subjects the relative contributions of insulin secretion, insulin-sensitivity (SI) and glucose-mediated (SG) glucose disposal to overall glucose tolerance, seven non-obese patients with thyrotoxicosis were studied by the minimal model analysis of the frequently sampled...

journal_title：Clinical endocrinology

authors： Pestell R,Alford F,Ramos R,Sawyer S,Best J,Ward G

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVE:In the present study we have performed a grey-scale quantitative analysis of thyroid echogenicity in the patients affected by Hashimoto's thyroiditis (HT), obtaining a numerical estimate of the degree of hypoechogenicity associated with the appearance of thyroid dysfunction. MATERIALS AND METHODS:The study g...

journal_title：Clinical endocrinology

authors： Mazziotti G,Sorvillo F,Iorio S,Carbone A,Romeo A,Piscopo M,Capuano S,Capuano E,Amato G,Carella C

更新日期：2003-08-01 00:00:00

abstract：OBJECTIVE:Patients on long-term dialysis may develop secondary hyperparathyroidism (SHPT), which causes varying degrees of bone mass loss. This condition is treated with parathyroidectomy (PTX). We investigated whether serial serum bone turnover markers could predict changes in bone mineral density (BMD) after PTX. DE...

journal_title：Clinical endocrinology

authors： Lu KC,Ma WY,Yu JC,Wu CC,Chu P

更新日期：2012-05-01 00:00:00

abstract：:A A 23-year-old man with secondary hypogonadism was also found to be thyrotoxic. Results of thyroid function tests were in the hyperthyroid range but the serum TSH was inappropriately high. A pituitary tumour was demonstrated and following hypophysectomy he became biochemically hypothyroid. Evidence is presented and d...

journal_title：Clinical endocrinology

authors： Baylis PH

更新日期：1976-03-01 00:00:00

abstract：OBJECTIVE:To assess the efficacy and safety of prenatal dexamethasone treatment in offspring at risk for congenital adrenal hyperplasia. METHODS:MEDLINE, EMBASE, the Cochrane Library, the clinicaltrials.gov website databases were systematically searched from inception through March 2019. WMD and SMD with 95%CIs were c...

journal_title：Clinical endocrinology

authors： Xu L,Lin W,Cai L,Huang H,Liang J,Li L,Zong L,Wang N,Wen J,Chen G

更新日期：2020-02-01 00:00:00

abstract：:Bilateral, selective and simultaneous catheterization of the inferior petrosal sinus with measurements of ACTH after stimulation with ovine corticotrophin-releasing factor (CRF) is now frequently used to establish the differential diagnosis in patients with Cushing's disease and to determine the side of the microadeno...

journal_title：Clinical endocrinology

authors： Schulte HM,Allolio B,Günther RW,Benker G,Winkelmann W,Ohnhaus EE,Reinwein D

更新日期：1988-03-01 00:00:00

abstract：OBJECTIVE:Whether nonalcoholic fatty liver disease (NAFLD) can predict atherosclerosis in obese patients remains unclear. The aim of our study was to investigate the usefulness of NAFLD and other cardiometabolic parameters in predicting subclinical atherosclerosis in obese patients. DESIGN, PATIENTS AND MEASUREMENTS:W...

journal_title：Clinical endocrinology

authors： Puig J,Blasco G,Daunis-I-Estadella J,Loshuertos E,Codina J,Cuba V,Ortiz R,Xifra G,Ricart W,Pedraza S,Federici M,Fernández-Real JM

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:Women with polycystic ovary syndrome (PCOS) have an increased risk of cardiovascular disease. The contribution of lipid abnormalities to this higher risk, in particular atherogenic modifications of low density lipoprotein (LDL) such as a shift towards smaller LDL, has not been properly explored. We aimed to e...

journal_title：Clinical endocrinology

authors： Dejager S,Pichard C,Giral P,Bruckert E,Federspield MC,Beucler I,Turpin G

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVE:The LMNA 1908C/T polymorphism has been reported to be associated with dyslipidaemia, metabolic syndrome, adipose tissue metabolism and obesity phenotypes, suggesting that this polymorphism presents an increased risk of atherosclerosis and vascular diseases. However, there have been no previous reports on the ...

journal_title：Clinical endocrinology

authors： Liang H,Murase Y,Katuta Y,Asano A,Kobayashi J,Mabuchi H

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:Androgens have paradoxically different effects on hair follicles depending on body site, stimulating beard growth while inducing regression in some areas of the scalp. The mesenchyme derived dermal papilla at the base of the hair follicle regulates many aspects of the growth of follicular epithelium, and is p...

journal_title：Clinical endocrinology

authors： Thornton MJ,Laing I,Hamada K,Messenger AG,Randall VA

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVE:Serum thyroglobulin (Tg) is a marker of residual differentiated thyroid cancer (DTC) after total thyroidectomy; however, circulating antithyroglobulin antibodies (TgAb) may interfere with the immunoassay for Tg. Ultrasensitive assays may have a more significant role in detecting circulating Tg in the context ...

journal_title：Clinical endocrinology

authors： McGrath RT,Preda VA,Clifton-Bligh P,Robinson B,Sywak M,Delbridge L,Ward P,Clifton-Bligh RJ,Learoyd DL

更新日期：2016-02-01 00:00:00