Mechanical properties of mammalian single smooth muscle cells. I. A low cost large range microforce transducer.

abstract：:Chronic low-frequency electrical stimulation of rabbit fast-twitch skeletal muscle induces increased levels of two intermediate filament proteins, desmin and vimentin, during the first 3 weeks of stimulation. These increases occur over the same timecourse as reported shifts in alpha-actinin expression and increased Z-...

journal_title：Journal of muscle research and cell motility

authors： Baldi JC,Reiser PJ

更新日期：1995-12-01 00:00:00

abstract：:Single muscle fiber sodium dodecyl sulfate polyacrylamide gel-electrophoresis (SDS-PAGE) is a sensitive technique for determining skeletal muscle myosin heavy chain (MHC) composition of human biopsy samples. However, the number of fibers suitable to represent fiber type distribution via this method is undefined. Muscl...

journal_title：Journal of muscle research and cell motility

authors： Murach KA,Bagley JR,McLeland KA,Arevalo JA,Ciccone AB,Malyszek KK,Wen Y,Galpin AJ

更新日期：2016-04-01 00:00:00

abstract：:Filamin binds to F-actin and influences the myosin-actin interaction. At relatively low concentrations, filamin activates actomyosin Mg2+-ATPase, whereas higher concentrations of filamin exert an inhibitory effect. Activation of ATPase activity occurs under conditions where a loose meshwork of actin filaments is prese...

journal_title：Journal of muscle research and cell motility

authors： Dabrowska R,Goch A,Osińska H,Szpacenko A,Sosinski J

更新日期：1985-02-01 00:00:00

abstract：:Skeletal muscle tissue is mechanosensitive, as it is able to sense mechanical impacts and to translate these into biochemical signals making the tissue adapt. Among its mechanosensitive nature, skeletal muscle tissue is the largest metabolic organ of the human body. Disturbances in skeletal muscle mechanosensing and m...

journal_title：Journal of muscle research and cell motility

authors： Pingel J,Suhr F

更新日期：2017-08-01 00:00:00

abstract：:Cleavage of vertebrate muscle tropomyosin by bacterial Omp T produces an amino-terminally truncated product (residues 7-284). The proteolysed protein, which is resolved from the parent by electrophoresis in the presence of sodium dodecylsulphate, can be generated from a variety of striated and smooth muscle tropomyosi...

journal_title：Journal of muscle research and cell motility

authors： Goonasekara CL,Gallivan LJ,Jackman DM,Heeley DH

更新日期：2007-01-01 00:00:00

abstract：:It is generally thought that the rapid relaxation of fast muscles is facilitated by the Ca(2+) binding protein parvalbumin (Parv). Indeed superfast swimbladder (SWB) muscle of toadfish contains the largest concentration of this protein ever observed (up to 1.5 mM). At 15 degrees C toadfish perform a 100 Hz call, 400 m...

journal_title：Journal of muscle research and cell motility

authors： Tikunov BA,Rome LC

更新日期：2009-01-01 00:00:00

abstract：:Because complex structural differences in adult extraocular muscles may have physiological and pathophysiological significance, the three-dimensional pattern of myosin heavy chain (MHC) isoform expression within the orbital and global layers of the muscle bellies compared with the distal tendon ends was quantitatively...

journal_title：Journal of muscle research and cell motility

authors： McLoon LK,Rios L,Wirtschafter JD

更新日期：1999-11-01 00:00:00

abstract：:There is evidence to suggest that 8 nm calcium transport particles in the sarcoplasmic reticulum are involved in the regulation of twitch properties in adult muscles. We have studied ultrastructural characteristics of the sarcoplasmic reticulum in relation to previously defined physiological changes that take place in...

journal_title：Journal of muscle research and cell motility

authors： Gauthier GF,Hobbs AW

更新日期：1986-04-01 00:00:00

abstract：:We investigated the regulatory roles of MgADP and free Ca2+ in isometric tension development in skinned bovine cardiac muscle. We found that, in the relaxed state without free Ca2+, MgADP elicited a sigmoidal increase in active tension, as is the case in skeletal muscle (ADP-contraction). The critical MgADP concentrat...

journal_title：Journal of muscle research and cell motility

authors： Fukuda N,Fujita H,Fujita T,Ishiwata S

更新日期：1998-11-01 00:00:00

abstract：:The giant molecule titin (also called connectin) provides an elastic connection in the I-band between the Z-disk and A-band of striated muscle. This region is assembled in a tissue-specific way by extensive differential splicing events. We have raised monoclonal antibodies against the two N2-line isoforms of titin and...

journal_title：Journal of muscle research and cell motility

authors： Gautel M,Lehtonen E,Pietruschka F

更新日期：1996-08-01 00:00:00

abstract：:The fine structure of leech body wall muscles, has been analysed under great length variations. All the measurable parameters of the fibre (distance between thick filaments, sarcomere and A band width, percentage of actin crowns around myosin filaments, fibre radius) at different elongations were tested with equations...

journal_title：Journal of muscle research and cell motility

authors： Lanzavecchia G,de Eguileor M,Valvassori R

更新日期：1985-10-01 00:00:00

abstract：:Hodges and his colleagues identified a 12 amino acid fragment of troponin I (TnI-ip) that inhibits Ca(2+)-activated force and reduces the effectiveness Ca(2+) as an activator. To understand the role of troponin C (TnC) in the extended cooperative interactions of thin filament activation, we compared the effect of TnI-...

journal_title：Journal of muscle research and cell motility

authors： Schachat F,Brandt PW

更新日期：2013-05-01 00:00:00

abstract：:The hypothesis that calmodulin (CaM) may act as a positive modulator of junctional SR Ca2+-release channel/ ryanodine receptor (RyRl) rests largerly on the demonstrated capacity of CaM to interact structurally and functionally with RyRl at pCa > 8 (Tripathy et al., 1995). The goal of the present [3H]-ryanodine binding...

journal_title：Journal of muscle research and cell motility

authors： Damiani E,Margreth A

更新日期：2000-01-01 00:00:00

abstract：:Rotary-shadowed filamin molecules appear as long, highly flexible rods curved into a variety of configurations. The particles observed were 2.7 nm wide but had contour lengths of either 98 nm or 193 nm. The longer particles are probably end-to-end dimers of the shorter but it is not clear how many polypeptide chains t...

journal_title：Journal of muscle research and cell motility

authors： Castellani L,Offer G,Elliott A,O'Brien EJ

更新日期：1981-06-01 00:00:00

abstract：:In this study the spontaneous activities of prescapular lymph nodes, which were isolated from calves, goats and sheep and mesenteric lymph nodes of guinea-pigs were recorded and analysed in the frequency domain. Stretch-evoked contractions of the mesenteric lymph nodes were also recorded and their frequency characteri...

journal_title：Journal of muscle research and cell motility

authors： Tümer A,Oztürk-Demir N,Basar-Eroğlu C,Noyan A

更新日期：1983-02-01 00:00:00

abstract：:This paper studies human gallbladder (GB) smooth muscle contractions. A two-state cross-bridge model was used to estimate the apparent attachment and detachment rate constants, as well as increased Ca2+ concentration from the peak active stress during the isometric contraction. The active stress was computed from a me...

journal_title：Journal of muscle research and cell motility

authors： Li WG,Luo XY,Hill NA,Ogden RW,Tian TH,Smythe A,Majeed AW,Bird N

更新日期：2011-11-01 00:00:00

abstract：:Isolated fibres from various muscles were skinned mechanically in oil. From a Ca2+-loaded micropipette, local applications of Ca2+ were made. These produced a limited contraction which relaxed spontaneously. The time-course of sarcomere shortening and re-lengthening was recorded by microcinephotography. Application of...

journal_title：Journal of muscle research and cell motility

authors： Gillis JM

更新日期：1997-08-01 00:00:00

abstract：:The optimal utilization of energy substrates in muscle fibers is of primary importance for muscle contraction and whole body physiology. This study aimed to investigate the age-related changes in some indicators of glucose catabolism and fatty acid oxidation in muscles of growing rabbits. Longissimus lumborum (fast-tw...

journal_title：Journal of muscle research and cell motility

authors： Gondret F,Damon M,Jadhao SB,Houdebine LM,Herpin P,Hocquette JF

更新日期：2004-01-01 00:00:00

abstract：:Changes in the isoform patterns of myosin heavy chains (MHC) and Ca2+-ATPase (SERCA) were studied in long-term (72 days) denervated slow-twitch soleus muscles of euthyroid and hyperthyroid rabbits. MHC isoforms were separated electrophoretically. SERCA isoforms were assessed by electrophoretic separation of the trypsi...

journal_title：Journal of muscle research and cell motility

authors： Hämäläinen N,Pette D

更新日期：2001-01-01 00:00:00

abstract：:Scallop S1 has a region sensitive to tryptic hydrolysis not found thus far in S1s of other species, located 65K from the N-terminus as determined by SDS/polyacrylamide-gel electrophoresis. In the presence of actin the S1 heavy chain is preferentially cleaved at this site. The high-salt EDTA and calcium ATPase activiti...

journal_title：Journal of muscle research and cell motility

authors： Szentkiralyi EM

更新日期：1987-08-01 00:00:00

abstract：:The mechanical events following release of ATP from P3-1-(2-nitro)phenylethyladenosine-5'-triphosphate (caged-ATP) in skinned guinea pig taenia coli smooth muscle in rigor were investigated. A rigor force of about 25-35% of the maximal active force was obtained by removing ATP at the plateau of a maximal active contra...

journal_title：Journal of muscle research and cell motility

authors： Arner A,Goody RS,Rapp G,Rüegg JC

更新日期：1987-10-01 00:00:00

abstract：:A set of five differential equations has been found which gives a satisfactory account of the isotonic and isometric properties of striated muscle. Four of these differential equations give an equally satisfactory account of the results of length-drive experiments with sinusoidal variation of length. In this case, the...

journal_title：Journal of muscle research and cell motility

authors： Cheung AS,Gray BF

更新日期：1984-10-01 00:00:00

abstract：:The details of the global and local structure and function of titin, a giant filamentous intrasarcomeric protein are largely undiscovered. Here we discuss a combination of bulk-solution and novel single-molecule techniques that may lend unique insights into titin's molecular dynamic, structural and mechanical characte...

journal_title：Journal of muscle research and cell motility

authors： Kellermayer MS,Grama L

更新日期：2002-01-01 00:00:00

abstract：:Myosin has been purified from chicken pectoralis muscle at various stages of development, from 10 days' incubation to approximately 10 months after hatching. Embryonic myosin from the earliest stage showed a high level of ATPase activity, similar to that obtained for adult pectoralis myosin. Two-dimensional peptide ma...

journal_title：Journal of muscle research and cell motility

authors： Lowey S,Benfield PA,LeBlanc DD,Waller GS

更新日期：1983-12-01 00:00:00

abstract：:temporaria (0.9-2.5degrees C) were stimulated to produce a 1 s isometric tetanus at regular intervals until constant mechanical responses were attained. Various degrees of force depression ("fatigue") were produced by decreasing the contraction interval from 30 or 15 min (control to 120, 60, 30 and 15s, respectively. ...

journal_title：Journal of muscle research and cell motility

authors： Edman KA,Mattiazzi AR

更新日期：1981-09-01 00:00:00

abstract：:Skeletal muscle has a remarkable ability to respond to different physical stresses. Loading muscle through exercise, either anaerobic or aerobic, can lead to increases in muscle size and function while, conversely, the absence of muscle loading stimulates rapid decreases in size and function. A principal mediator of t...

journal_title：Journal of muscle research and cell motility

authors： Graham ZA,Gallagher PM,Cardozo CP

更新日期：2015-10-01 00:00:00

abstract：:The β-adrenergic receptor stimulation improves endurance in fast twitch muscles and these effects are sensitive to extracellular Ca2+ influx. Present study is aimed to determine the effects of adrenaline, with different concentrations of extracellular Ca2+[Formula: see text], on the contractility and endurance of slow...

journal_title：Journal of muscle research and cell motility

authors： Rizvi MH,Abdul Azeem M,Savanur A

更新日期：2019-12-01 00:00:00

abstract：:High speed isovelocity shortening using a servo-controlled lever was performed on isolated whole frog sartorius muscles at long lengths to ensure substantial passive tension. The tension records of unstimulated control experiments were subtracted from the tension records of fully-tetanized experiments on the same musc...

journal_title：Journal of muscle research and cell motility

authors： Seo JS,Krause PC,McMahon TA

更新日期：1994-02-01 00:00:00

abstract：:Twitchin, also called mini-titin, is structurally related to the giant elastic protein connectin/titin, and has been found in not only striated but also smooth muscles of bivalves. Many bivalve smooth muscles such as byssus retractor muscles and the opaque part of adductor muscles are known as catch muscles that can m...

journal_title：Journal of muscle research and cell motility

authors： Tsutsui Y,Yoshio M,Oiwa K,Yamada A

更新日期：2005-01-01 00:00:00

abstract：:The efficacy of the 'EGTA-treatment' for producing a model of selectively 'skinned' cardiac muscle has been questioned. This paper deals with ultrastructural evidence designed to test whether small ions can gain access to the myofibrillar space of the heart after 'EGTA-treatment'. Lanthanum has been employed because o...

journal_title：Journal of muscle research and cell motility

authors： Miller DJ,Elder HY,Smith GL

更新日期：1985-10-01 00:00:00