Gene therapy for corneal dystrophies and disease, where are we?

abstract：PURPOSE OF REVIEW:The function is described of the Implantable Miniature Telescope, which is completing clinical development for bilateral end-stage macular degeneration, and 6-month results of the Phase II/III IMT002 prospective, multicenter study are presented. Multispecialty patient management and implications of th...

journal_title：Current opinion in ophthalmology

authors： Lane SS,Kuppermann BD

更新日期：2006-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss a new class of medication that has recently become available for the treatment of glaucoma; as well as share insights into developments in glaucoma medicine administration which has the potential to revolutionize medical therapy for glaucoma. RECENT FINDINGS:Newly available eye drops, neta...

journal_title：Current opinion in ophthalmology

authors： Ostler E,Rhee D,Burney E,Sozeri Y

更新日期：2020-12-30 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this article is to assess the current state of teleophthalmology given the sudden surge in telemedicine demand in response to the novel coronavirus 2019 (COVID-19). RECENT FINDINGS:Recommendations and policies from government and national health organizations, combined with social distanci...

journal_title：Current opinion in ophthalmology

authors： Kalavar M,Hua HU,Sridhar J

更新日期：2020-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The phakomatoses are a group of inherited disorders with variable clinical manifestations that are characterized by brain, cutaneous, ocular and other distinct lesions in multiple organs. Correctly recognizing the neuro-ophthalmic signs and symptoms can lead to early diagnosis and treatment. The group...

journal_title：Current opinion in ophthalmology

authors： Douglas KAA,Douglas VP,Cestari DM

更新日期：2019-11-01 00:00:00

abstract：:Ophthalmologic nystagmus can be congenital and manifest/latent both of whose waveforms, compensatory mechanisms, and treatment are different. Physiologically, latent nystagmus may be reversed at will, whereas nystagmus and head nodding may be simultaneously triggered at will. Occasional oscillopsia is more frequent th...

journal_title：Current opinion in ophthalmology

authors： Spielmann A

更新日期：1994-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Toxic anterior segment syndrome (TASS) is a surgical complication resulting from a noninfectious inflammatory reaction to substances used during intraocular ophthalmic surgery. Continuous reporting of new information concerning risk factors and possible causes is critical for preventing this condition...

journal_title：Current opinion in ophthalmology

authors： Shouchane-Blum K,Dotan A,Bahar I

更新日期：2019-01-01 00:00:00

abstract：:The status of the cornea is crucial to a good outcome with cataract extraction. Preexisting corneal disease must be managed appropriately to get the high quality results that we have come to expect with modern day cataract surgery. It is now more common to perform cataract surgery on patients who have had previous cor...

journal_title：Current opinion in ophthalmology

authors： Preschel N,Hardten DR

更新日期：1998-02-01 00:00:00

abstract：:Patients with Alzheimer's disease may present to the ophthalmologist with visual symptoms that precede or overshadow the features of dementia. This visual variant of Alzheimer's disease has been recognized only recently and typically appears in late middle age as progressive visuospatial and reading dysfunction, with ...

journal_title：Current opinion in ophthalmology

authors： Fletcher WA

更新日期：1994-12-01 00:00:00

abstract：:Human amniotic membrane (AM) is composed of three layers: a single epithelial layer, a thick basement membrane, and an avascular stroma. Amniotic membrane has anti-adhesive properties and is felt to promote epithelialization and decrease inflammation, neovascularization, and fibrosis. Amniotic membrane transplantation...

journal_title：Current opinion in ophthalmology

authors： Sippel KC,Ma JJ,Foster CS

更新日期：2001-08-01 00:00:00

abstract：:The surgical management of Graves ophthalmopathy includes treatment of globe malposition (exophthalmos), strabismus, and eyelid abnormalities. The various techniques used continue to be refined and are detailed in this review. ...

journal_title：Current opinion in ophthalmology

authors： Meyer DR

更新日期：1999-10-01 00:00:00

abstract：:Vascular occlusions of the retina and choroid can cause severe visual loss. These occlusions can occur as a result of systemic disease or after surgery. In most cases, the retinal appearance provides evidence of ischemia as the cause of visual loss. On occasion, however, clinical examination shows no objective signs o...

journal_title：Current opinion in ophthalmology

authors： Zacks DN,Rizzo JF

更新日期：1999-12-01 00:00:00

abstract：:Giant cell arteritis is a systemic disease that can have devastating ophthalmic consequences. New insights into the epidemiology and pathophysiology of the disease may improve early diagnosis and treatment. ...

journal_title：Current opinion in ophthalmology

authors： Tovilla-Canales JL

更新日期：1998-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review summarizes factors for progression in the Early Manifest Glaucoma Trial (EMGT), including the effect of treatment. EMGT randomized patients with early glaucoma either to argon laser trabeculoplasty plus betaxolol (n = 129) or to no immediate treatment (n = 126) and followed them every 3 mo...

journal_title：Current opinion in ophthalmology

authors： Leske MC,Heijl A,Hyman L,Bengtsson B,Komaroff E

更新日期：2004-04-01 00:00:00

abstract：:Porous high-density polyethylene implants have become well accepted for the repair of orbital wall fractures, delayed orbital reconstruction, orbital rim and malar bony onlay augmentation, and volume replacement as orbital spherical implants for the treatment of anophthalmos. Medpor (Porex Surgical, Inc. College Park,...

journal_title：Current opinion in ophthalmology

authors： Purdy EP

更新日期：1997-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To review recent studies on potential neurodevelopmental impacts on the pediatric population through general anesthesia events or intravitreal anti-vascular endothelial growth factor (VEGF) injection. RECENT FINDINGS:Studies on this topic have been extensive with varied reported neurodevelopmental ou...

journal_title：Current opinion in ophthalmology

authors： De Andrade LM,Isenberg SJ

更新日期：2019-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To present an overview on the clinical manifestations and an update on the current management of neuromyelitis optica (NMO). RECENT FINDINGS:NMO is associated with a significant risk of neurological, ocular and systemic morbidity. Many cases of NMO assume a relapsing course, which can lead clinicians...

journal_title：Current opinion in ophthalmology

authors： Hazin R,Khan F,Bhatti MT

更新日期：2009-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Although lens surgery for high myopia has a long History, it has been extremely controversial. Colin's study of 1999 indicated a much higher than expected rate of retinal detachment. The purpose of this review is to reassess the place of refractive lens exchange in high myopia in the light of more rec...

journal_title：Current opinion in ophthalmology

authors： Packard R

更新日期：2005-02-01 00:00:00

abstract：:Retinopathy of prematurity (ROP) is a potentially blinding condition that afflicts preterm infants in the neonatal period. Although advances in scleral buckling and vitrectomy techniques offer hope for those infants suffering from stage 4 or 5 ROP, prevention of progression to these stages offers the most promise for ...

journal_title：Current opinion in ophthalmology

authors： Banach MJ,Berinstein DM

更新日期：2001-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Meibomian gland dysfunction (MGD) is understood to be a highly prevalent, chronic progressive disease and the leading cause of dry eye. All available published peer-reviewed results of the novel vectored thermal pulsation therapy for patients with MGD are investigated. RECENT FINDINGS:The PubMed and ...

journal_title：Current opinion in ophthalmology

authors： Blackie CA,Carlson AN,Korb DR

更新日期：2015-07-01 00:00:00

abstract：PURPOSE OF REVIEW:This review summarizes the recent literature of the impact of cataract surgery from the patient's perspective, with a focus on second-generation patient reported outcome (PRO) measures that used Rasch analysis to explore their data. RECENT FINDINGS:Irrespective of the instrument utilized, the overrid...

journal_title：Current opinion in ophthalmology

authors： Lamoureux EL,Fenwick E,Pesudovs K,Tan D

更新日期：2011-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Pseudoexfoliation syndrome (XFS) is a late-onset and complex disorder that is strongly associated with the development of glaucoma. The purpose of this review is to discuss the inheritance patterns and recent genetic advances in the study of this disorder. RECENT FINDINGS:XFS has a strong familial as...

journal_title：Current opinion in ophthalmology

authors： Challa P

更新日期：2009-03-01 00:00:00

abstract：:Ocular manifestations of systemic malignancy are important for both the ophthalmologist and the internist to recognize because they may precede the diagnosis of cancer. This review of the current literature discusses the clinical manifestations, etiology, and potential therapeutic interventions for a group of visual p...

journal_title：Current opinion in ophthalmology

authors： Solomon SD,Smith JH,O'Brien J

更新日期：1999-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The diagnosis and successful treatment of visually significant refractive errors in children are a subject of continued study and debate. RECENT FINDINGS:Treatment of significant refractive errors is widely accepted to reduce lifelong vision loss from amblyopia. Children aged 3-5 years may be screene...

journal_title：Current opinion in ophthalmology

authors： Braverman R

更新日期：2007-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Posterior vitreous detachment is the principal predisposing event for the development of retinal breaks and rhegmatogenous retinal detachments. Patients with unilateral posterior vitreous detachment are potentially at risk of developing the complications associated with posterior vitreous detachment i...

journal_title：Current opinion in ophthalmology

authors： Hikichi T

更新日期：2007-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The phaco machine is frequently overlooked as the crucial surgical instrument it is. Understanding how to set parameters is initiated by understanding fundamental concepts of machine function. RECENT FINDINGS:This study analyses the critical concepts of partial occlusion phaco, occlusion phaco and pu...

journal_title：Current opinion in ophthalmology

authors： Fishkind WJ

更新日期：2013-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe recent advances in clinical features, diagnostic tools, and treatment modalities for lymphoproliferative diseases affecting the ocular adnexa. RECENT FINDINGS:A close relationship of non-Hodgkin lymphoma with long-term use of aspirin and nonaspirin nonsteroidal antiinflammatory drugs has ...

journal_title：Current opinion in ophthalmology

authors： Tovilla-Canales JL,Tovilla y Pomar JL,Ceron JR

更新日期：2004-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Although researchers continue to investigate the multifarious etiologic, anatomical, physiological, and pathological factors of dry eye, successful treatment remains a challenge. RECENT FINDINGS:Dry eye prevalence is substantial across populations and the term 'dry eye' is used to describe numerous c...

journal_title：Current opinion in ophthalmology

authors： Abelson MB,Ousler GW 3rd,Maffei C

更新日期：2009-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Asians make up the world's largest ethnic group, and the eyelid is one of the most prominent features of the face, regardless of race. Recent advances in Asian eyelid research have improved the understanding of its unique anatomy and, more importantly, highlighted differences surgeons should be aware ...

journal_title：Current opinion in ophthalmology

authors： Saonanon P

更新日期：2014-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The concept of neuroprotective therapy for glaucoma is that damage to retinal ganglion cells (RGCs) may be prevented by intervening in neuronal death pathways. This review focuses on strategies for neuroprotection and summarizes preclinical studies that have investigated potential agents over the last...

journal_title：Current opinion in ophthalmology

authors： Danesh-Meyer HV

更新日期：2011-03-01 00:00:00

abstract：:Glaucoma surgery has evolved over the past 30 years from the full-thickness procedure to the guarded filtration procedure. However, many of the risks and complications attendant with the full-thickness procedure, including endophthalmitis, hypotony, cataract progression, and filtration failure, continue to plague the ...

journal_title：Current opinion in ophthalmology

authors： Borisuth NS,Phillips B,Krupin T

更新日期：1999-04-01 00:00:00