Ophthalmological aspects of Alzheimer's disease.

Abstract:

:Patients with Alzheimer's disease may present to the ophthalmologist with visual symptoms that precede or overshadow the features of dementia. This visual variant of Alzheimer's disease has been recognized only recently and typically appears in late middle age as progressive visuospatial and reading dysfunction, with normal visual acuity and fields. Common features include simultanagnosia and the other features of Balint's syndrome, and variable hemispatial neglect and hemianopia. The neuroimaging and neuropathological findings in this Alzheimer's variant are distinct and suggest disruption of occipitoparietal visual projections. The identification of the visually symptomatic patient who is destined to develop other signs of Alzheimer's disease depends on the use of appropriate screening tests, including text reading, figure-ground discrimination, and other bedside tests of visuospatial attention and perception.

journal_name

Curr Opin Ophthalmol

authors

Fletcher WA

keywords:

subject

Has Abstract

pub_date

1994-12-01 00:00:00

pages

38-44

issue

6

eissn

1040-8738

issn

1531-7021

journal_volume

5

pub_type

杂志文章,评审
  • Contrast sensitivity: determining the visual quality and function of cataract, intraocular lenses and refractive surgery.

    abstract:PURPOSE OF REVIEW:This review provides an update of recent advances in understanding the quality and functional significance of contrast sensitivity for the clinician regarding cataract, intraocular lenses and refractive surgery that goes beyond the measurement of visual acuity. RECENT FINDINGS:New American National S...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/01.icu.0000192520.48411.fa

    authors: Ginsburg AP

    更新日期:2006-02-01 00:00:00

  • Current concepts in vitreomacular traction syndrome.

    abstract:PURPOSE OF REVIEW:As Reese first described the vitreomacular traction (VMT) syndrome in 1970, the knowledge base about the disease has been changing over time due to the advent of the high-definition optical coherence tomography (HD-OCT). The aim of this article was to present the current information on the pathophysio...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0b013e328352404c

    authors: Bottós JM,Elizalde J,Rodrigues EB,Maia M

    更新日期:2012-05-01 00:00:00

  • Vascular risk factors in glaucoma.

    abstract::The role of the villain in high-pressure glaucoma is played by ocular hypertension. Alterations of lamina cribosa, other mechanical alterations, and a possible loss of optic nerve head capillaries are all accountable, and from a therapeutic standpoint most clinicians readily perceive that lowering ocular pressure is t...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:

    authors: Béchetoille A

    更新日期:1996-04-01 00:00:00

  • The antiphospholipid antibody syndrome.

    abstract::Antiphospholipid syndrome includes elevation of either the lupus anticoagulant titer or the anticardiolipin antibody titer on two occasions, separated by 6 weeks in a patient with an episode of thrombosis. The eye is involved frequently in patients with antiphospholipid syndrome. Patients with retinal vascular disease...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/00055735-200006000-00011

    authors: Bolling JP,Brown GC

    更新日期:2000-06-01 00:00:00

  • Health literacy and glaucoma.

    abstract:PURPOSE OF REVIEW:This review discusses the concept and measurement of health literacy, with a focus on the care of patients with glaucoma. RECENT FINDINGS:Nearly one-fourth of adults in the USA lack the skills needed to fully comprehend and act on verbal or written information in the healthcare environment. This prob...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0b013e32835c8b0e

    authors: Muir KW,Christensen L,Bosworth HB

    更新日期:2013-03-01 00:00:00

  • Intraocular lens calculations in patients with keratoectatic disorders.

    abstract:PURPOSE OF REVIEW:Intraocular lens (IOL) calculations in patients with keratoconus and other keratoectatic disorders continues to be a challenge for today's cataract surgeon. In this article, we review data published over the past 18 months (June 2018 to January 2020). RECENT FINDINGS:Cataract surgery in keratoconus p...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0000000000000671

    authors: Smith RG,Knezevic A,Garg S

    更新日期:2020-07-01 00:00:00

  • Selectivity of site of action and systemic effects of topical alpha agonists.

    abstract::Clonidine hydrochloride, apraclonidine hydrochloride, and brimonidine tartrate constitute the three topical alpha agonists that are used in the treatment of elevated intraocular pressure. All the alpha agonists have prejunctional (alpha 2) as well as postjunctional (alpha 1) effects. Within the past year, questions ha...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/00055735-199804000-00006

    authors: Robin AL,Burnstein Y

    更新日期:1998-04-01 00:00:00

  • Multifocal intraocular lenses in the setting of glaucoma.

    abstract:PURPOSE OF REVIEW:The purpose of this review is to collate evidence and make recommendations regarding the use of multifocal intraocular lenses in patients with glaucoma. RECENT FINDINGS:Multifocal intraocular implants have been in use since the 1980s. Several studies have been done comparing their advantages and disa...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0b013e328011d108

    authors: Kumar BV,Phillips RP,Prasad S

    更新日期:2007-02-01 00:00:00

  • Comparison of designs of laser systems utilized for refractive surgery.

    abstract::Several different laser types are available on the market for the practitioner to use in refractive surgery. Each laser type has certain parameters that the surgeon must understand to obtain the best refractive outcomes. Studies published in peer-reviewed literature between February 2002 and March 2003 show that refra...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/00055735-200308000-00008

    authors: Hardten DR,Hauswirth SG

    更新日期:2003-08-01 00:00:00

  • Glaucoma therapy and ocular surface disease: current literature and recommendations.

    abstract:PURPOSE OF REVIEW:To provide an update on clinical and experimental literature for ocular surface effects of glaucoma therapy and to provide practical guidelines for ophthalmologists treating glaucoma patients with ocular surface disease (OSD). RECENT FINDINGS:Preservatives, notably benzalkonium chloride (BAK), contin...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0b013e32835c8aba

    authors: Anwar Z,Wellik SR,Galor A

    更新日期:2013-03-01 00:00:00

  • Amblyopia.

    abstract::New knowledge of the pathophysiology of amblyopia has evolved through animal research over the past 30 years. We now know that development and treatment of amblyopia have a critical and sensitive period. After more than a millennium, patching of the dominant eye remains the cornerstone of amblyopia treatment, and comp...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/00055735-199610000-00003

    authors: de Faber JT,Kingma-Wilschut C

    更新日期:1996-10-01 00:00:00

  • Endothelium-derived vasoactive substances relevant to normal-tension glaucoma.

    abstract::Glaucoma is a progressive optic neuropathy that has a multi-factorial etiology. The most important risk factor is certainly an increased intraocular pressure. However, clinical observations have indicated that factors other than increased intraocular pressure also damage the neural tissue in glaucomatous optic neuropa...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/00055735-199804000-00016

    authors: Orgül S,Prünte C,Flammer J

    更新日期:1998-04-01 00:00:00

  • Use of botulinum toxin in strabismus.

    abstract:PURPOSE OF REVIEW:The history, pharmacology, indications, complications, and success rates of botulinum administration are discussed in this review as they relate to strabismus and associated conditions. RECENT FINDINGS:Botulinum has been used to treat strabismus and a variety of other ocular conditions for over three...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/01.icu.0000243018.97627.4c

    authors: Crouch ER

    更新日期:2006-10-01 00:00:00

  • The phaco machine: analysing new technology.

    abstract:PURPOSE OF REVIEW:The phaco machine is frequently overlooked as the crucial surgical instrument it is. Understanding how to set parameters is initiated by understanding fundamental concepts of machine function. RECENT FINDINGS:This study analyses the critical concepts of partial occlusion phaco, occlusion phaco and pu...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0b013e32835b0770

    authors: Fishkind WJ

    更新日期:2013-01-01 00:00:00

  • eyeGENE(R): a novel approach to combine clinical testing and researching genetic ocular disease.

    abstract:PURPOSE OF REVIEW:Molecular genetics is revolutionizing the diagnosis and treatment of inherited eye diseases. The National Eye Institute of the National Institutes of Health (NIH), in an effort to facilitate future basic and clinical research in inherited eye disease, created The National Ophthalmic Disease Genotyping...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0b013e32835715c9

    authors: Goetz KE,Reeves MJ,Tumminia SJ,Brooks BP

    更新日期:2012-09-01 00:00:00

  • Myelin oligodendrocyte glycoprotein-IgG-associated optic neuritis.

    abstract:PURPOSE OF REVIEW:Myelin oligodendrocyte glycoprotein (MOG)-IgG-associated optic neuritis has been established as a new entity of optic neuropathy. We will review recent advances in pathophysiology, diagnosis, and clinical manifestations of MOG-IgG-associated optic neuritis to better understand its distinctive characte...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0000000000000520

    authors: Chun BY,Cestari DM

    更新日期:2018-11-01 00:00:00

  • Macular translocation.

    abstract::Macular translocation is a term used to describe any surgical procedure that involves the deliberate detachment of the retina with subsequent repositioning of the macula to a new location relative to the underlying retinal pigment epithelium. By moving the fovea away from abnormal pigment epithelium and/or choroid and...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/00055735-200006000-00001

    authors: Vander JF

    更新日期:2000-06-01 00:00:00

  • Teleophthalmology: an essential tool in the era of the novel coronavirus 2019.

    abstract:PURPOSE OF REVIEW:The aim of this article is to assess the current state of teleophthalmology given the sudden surge in telemedicine demand in response to the novel coronavirus 2019 (COVID-19). RECENT FINDINGS:Recommendations and policies from government and national health organizations, combined with social distanci...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0000000000000689

    authors: Kalavar M,Hua HU,Sridhar J

    更新日期:2020-09-01 00:00:00

  • Criteria for success of surgical treatment of glaucoma.

    abstract::Outcome measures for studies of the surgical treatment of glaucoma include intraocular pressure, functional status (usually with visual field measurements), and structural status of the optic nerve or nerve fiber layer. Older studies relied heavily and almost solely on intraocular pressure as a surrogate measure for e...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/00055735-199704000-00013

    authors: Caprioli J

    更新日期:1997-04-01 00:00:00

  • Corneal complications of cataract surgery.

    abstract::Recent advances in cataract surgery have reduced the incidence of corneal complications. Review of the current literature reveals a trend toward early visual rehabilitation and minimization of postoperative astigmatism by careful selection of incision type and location for small-incision cataract surgery. Since the in...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/00055735-199608000-00010

    authors: Batlan SJ,Dodick JM

    更新日期:1996-08-01 00:00:00

  • Advances in refractive surgery: microkeratome and femtosecond laser flap creation in relation to safety, efficacy, predictability, and biomechanical stability.

    abstract:PURPOSE OF REVIEW:Methods of flap creation have changed over the years from the evolution of the mechanical microkeratome to the introduction of the IntraLase femtosecond laser keratome, both of which have different mechanisms of action to create corneal resections. Previous studies report the advantages and disadvanta...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/01.icu.0000233957.88509.2d

    authors: Stonecipher K,Ignacio TS,Stonecipher M

    更新日期:2006-08-01 00:00:00

  • Optical coherence tomography and cataract surgery.

    abstract:PURPOSE OF REVIEW:To provide an unstructured review of the recent literature on the role of optical coherence tomography (OCT) in cataract surgery with specific focus on cystoid macular edema (CME) on the basis of expert opinion of the authors. RECENT FINDINGS:OCT appears to be a useful method to reveal clinically rel...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/icu.0b013e3283199162

    authors: Kim SJ,Bressler NM

    更新日期:2009-01-01 00:00:00

  • Does general anesthesia or intravitreal injection affect neurodevelopment in children undergoing ophthalmic procedures?

    abstract:PURPOSE OF REVIEW:To review recent studies on potential neurodevelopmental impacts on the pediatric population through general anesthesia events or intravitreal anti-vascular endothelial growth factor (VEGF) injection. RECENT FINDINGS:Studies on this topic have been extensive with varied reported neurodevelopmental ou...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0000000000000598

    authors: De Andrade LM,Isenberg SJ

    更新日期:2019-09-01 00:00:00

  • Diabetes and thyroid-related eye disease.

    abstract::Diabetes and thyroid-related eye disease cause significant morbidity. Although these are endocrine disorders, they cause different ocular manifestations. Previously unexamined epidemiologic factors offer new insight to diabetic eye disease. The association of hyperglycemia, systemic medical therapy, and visual loss is...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/00055735-199412000-00011

    authors: Feman SS

    更新日期:1994-12-01 00:00:00

  • Cosmetic blepharoplasty.

    abstract::Performing flawless cosmetic blepharoplasty surgery requires attention to many details. A proper medical work-up with establishment of patient rapport and preoperative photographic documentation should begin the evaluation. The surgical correction of concomittant brow position abnormalities should be considered. Res...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/00055735-199110000-00013

    authors: Bosniak SL,McDevitt TF

    更新日期:1991-10-01 00:00:00

  • Laser treatment in eyes with drusen.

    abstract::During the past several decades, many individuals have noted that drusen may resolve after macular laser photocoagulation. The lack of effective therapies against choroidal neovascularization (CNV) due to age-related macular degeneration (AMD) has prompted many invesigators to explore strategies designed to prevent CN...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/00055735-199906000-00009

    authors: Ho AC

    更新日期:1999-06-01 00:00:00

  • Cataract surgery in patients with prior refractive surgery.

    abstract::As the number and types of keratorefractive procedures increase and as the baby boomer population moves into the "cataractous decades," the number of patients requiring cataract surgery following refractive surgery grows larger each year. While technological advances in surgical instrumentation and intraocular lens (I...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/00055735-200302000-00008

    authors: Hamilton DR,Hardten DR

    更新日期:2003-02-01 00:00:00

  • Horner syndrome.

    abstract::Horner syndrome refers to the constellation of signs resulting from the interruption of sympathetic innervation to the eye and ocular adnexae. Classically, the clinical findings include a triad of ipsilateral blepharoptosis, pupillary miosis, and facial anhidrosis. The history, additional clinical examination features...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/00055735-200312000-00007

    authors: Walton KA,Buono LM

    更新日期:2003-12-01 00:00:00

  • Posterior vitreous detachment and retinal detachment following cataract extraction.

    abstract:PURPOSE OF THE REVIEW:Cataract surgery induces considerable vitreous modifications that can lead to posterior vitreous detachment. Studies indicate that these changes, whether combined or not with peripheral retinal degenerations such as lattice areas, carry risk for subsequent retinal breaks or detachment. RECENT FIN...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/ICU.0b013e3282fc9c4a

    authors: Coppé AM,Lapucci G

    更新日期:2008-05-01 00:00:00

  • Clinical implications of vascular growth factors in proliferative retinopathies.

    abstract::Angiogenesis is a fundamental component of normal development and pathologic processes within the eye. Complications due to abnormal ocular neovascularization remain the leading cause of visual loss throughout the world today. Neovascularization and the associated increase in vascular permeability are the underlying t...

    journal_title:Current opinion in ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1097/00055735-199706000-00005

    authors: Aiello LP

    更新日期:1997-06-01 00:00:00