Glaucoma therapy and ocular surface disease: current literature and recommendations.

Abstract:

PURPOSE OF REVIEW:To provide an update on clinical and experimental literature for ocular surface effects of glaucoma therapy and to provide practical guidelines for ophthalmologists treating glaucoma patients with ocular surface disease (OSD). RECENT FINDINGS:Preservatives, notably benzalkonium chloride (BAK), continue to contribute to OSD and demonstrate a variety of toxic ocular effects both in-vitro, and in animal/human studies. Recent literature frequently compares BAK with Polyquad, SofZia, and preservative-free therapies. Some clinical benefit has been demonstrated with newer BAK-free alternatives. SUMMARY:BAK-free and preservative-free therapies are becoming available but are not always a feasible alternative. It is important to recognize different clinical manifestations of allergy and chronic inflammation and to discuss options for patients experiencing OSD.

journal_name

Curr Opin Ophthalmol

authors

Anwar Z,Wellik SR,Galor A

doi

10.1097/ICU.0b013e32835c8aba

subject

Has Abstract

pub_date

2013-03-01 00:00:00

pages

136-43

issue

2

eissn

1040-8738

issn

1531-7021

pii

00055735-201303000-00009

journal_volume

24

pub_type

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