Abstract:
PURPOSE OF REVIEW:The purpose of this study is to discuss current controversies surrounding the proposed treatments for traumatic optic neuropathy (TON) and review recent evidence from the literature relating to these therapeutic options. RECENT FINDINGS:No recent randomized controlled trials investigating surgical or medical interventions for TON exist. The current literature regarding treatment of TON consists mainly of small, mostly retrospective, observational studies. Treatment of TON with corticosteroids, surgical decompression of the optic canal or combinations of surgery and corticosteroids does not appear to offer improved visual outcomes compared with observation alone. Recent evidence suggests that there may be diminished functional reserve of the optic nerve following trauma. Novel neuroprotective therapies, such as erythropoietin, are currently under investigation in the treatment of TON. SUMMARY:TON may lead to profound visual disability. Because of the absence of Class I evidence relating to treatment of TON, a lack of consensus exists among clinicians regarding the appropriate treatment for TON. Our review of the recent literature finds that there is still no reliable evidence that treatment of TON with corticosteroids, surgical optic canal decompression or both confers any benefit over observation alone, and yet these interventions incur an additional risk that may not warrant their routine use.
journal_name
Curr Opin Ophthalmoljournal_title
Current opinion in ophthalmologyauthors
Chaon BC,Lee MSdoi
10.1097/ICU.0000000000000198subject
Has Abstractpub_date
2015-11-01 00:00:00pages
445-9issue
6eissn
1040-8738issn
1531-7021pii
00055735-201511000-00003journal_volume
26pub_type
杂志文章,评审abstract:PURPOSE OF REVIEW:Sarcoidosis is a multisystemic inflammatory disease that commonly affects the eye and less often the neuro-ophthalmic pathways. The manifestations can be quite variable but can have characteristic signs and clinical features. This review provides a comprehensive overview of the various ocular and neur...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000415
更新日期:2017-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Recent developments in the diagnosis and management of sickle cell ocular manifestations are reviewed to enable the clinician to better manage the ophthalmic care of these patients. RECENT FINDINGS:Research over the past year has focused upon systemic and ocular clues to the presence of sickle cell r...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e328358b921
更新日期:2012-11-01 00:00:00
abstract::Modern molecular genetics has had a profound effect on our understanding of corneal dystrophies. Mutations in the BIGH3 gene are responsible for four autosomal dominant corneal dystrophies. The mutation spectrum reveals the phenotypically diverse possibilities stemming from mutations of a single gene. Dystrophies have...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-200208000-00002
更新日期:2002-08-01 00:00:00
abstract:PURPOSE OF REVIEW:The aim of this article is to review techniques to maximize all-distance uncorrected visual acuity and minimize photic phenomena after the implantation of multifocal and extended-depth of focus (EDOF) intraocular lenses (IOLs). This review examines the role of femtosecond laser-assisted cataract surge...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000723
更新日期:2021-01-01 00:00:00
abstract::Healing of corneal wounds is a complex process involving epithelial, keratocyte, and endothelial interactions that are affected by their associations with wound bed matrix and by cytokine availability and activation. The spectrum of possible cellular-matrix-growth factor interactions is indeed great and growing. Sever...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199508000-00002
更新日期:1995-08-01 00:00:00
abstract::Improvements in the management of strabismus are largely dependent on making the specific diagnosis and differentiating patterns of strabismus. This finding is especially true in the management of superior oblique paresis because there are various types. Recent observation suggests that superior oblique paresis may ...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199310000-00004
更新日期:1993-11-01 00:00:00
abstract::Angiogenesis is a fundamental component of normal development and pathologic processes within the eye. Complications due to abnormal ocular neovascularization remain the leading cause of visual loss throughout the world today. Neovascularization and the associated increase in vascular permeability are the underlying t...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199706000-00005
更新日期:1997-06-01 00:00:00
abstract:PURPOSE OF REVIEW:The diagnosis and successful treatment of visually significant refractive errors in children are a subject of continued study and debate. RECENT FINDINGS:Treatment of significant refractive errors is widely accepted to reduce lifelong vision loss from amblyopia. Children aged 3-5 years may be screene...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e328244dfed
更新日期:2007-09-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose is to summarize treatment strategies in idiopathic intracranial hypertension (IIH), a potentially sight-threatening disease, with a focus on the most current outcome data for venous sinus stenting. RECENT FINDINGS:Historically, the primary treatment options for medically refractory IIH co...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000315
更新日期:2016-11-01 00:00:00
abstract::Since the publication of my last article in Current Opinion in Ophthalmology in 1991 (2:33-34), the use of multifocal intraocular lenses (IOLs) has not gained general acceptance among ophthalmologists. Despite this situation, major IOL companies have continued to invest in clinical trials of new designs. Recently, lar...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:1996-02-01 00:00:00
abstract:PURPOSE OF REVIEW:To discuss the risks, benefits and value of genetic testing for ocular genetic disease. RECENT FINDINGS:Testing for ocular genetics diseases is becoming more available and successful gene therapy is being reported. Clinicians must prepare for this trend by considering diagnostic genetic testing for t...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000083
更新日期:2014-09-01 00:00:00
abstract:PURPOSE OF REVIEW:To describe trends in corneal transplantation surgery, including indications for surgery, evolution of lamellar keratoplasty, current surgical techniques, and future directions. RECENT FINDINGS:Over the past decade, anterior and posterior lamellar keratoplasty have begun to supplant penetrating kerat...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000080
更新日期:2014-07-01 00:00:00
abstract::There have been many recent advances in the diagnosis and management of children with retinoblastoma. Regarding diagnosis, the judicial use of ancillary studies, particularly B-scan ultrasonography, has been instrumental in supplementing the diagnosis when opaque media preclude a clear view of the underlying neoplasm...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199406000-00014
更新日期:1994-06-01 00:00:00
abstract:PURPOSE OF REVIEW:The objective of this review is to evaluate the result of cataract surgery in patients continuing antiplatelet and/or anticoagulant treatment. RECENT FINDINGS:The number of elderly patients using anticoagulant and antiplatelet treatment in prevention of venous thromboembolism has significantly increa...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000117
更新日期:2015-01-01 00:00:00
abstract:PURPOSE OF REVIEW:Asians make up the world's largest ethnic group, and the eyelid is one of the most prominent features of the face, regardless of race. Recent advances in Asian eyelid research have improved the understanding of its unique anatomy and, more importantly, highlighted differences surgeons should be aware ...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000075
更新日期:2014-09-01 00:00:00
abstract:PURPOSE OF REVIEW:The management of retinoblastoma is complex and involves strategically chosen methods of enucleation, radiotherapy, chemotherapy, laser photocoagulation, thermotherapy, and cryotherapy. Chemotherapy has become the most common eye-sparing modality. There are four routes of delivery of chemotherapy for ...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000091
更新日期:2014-09-01 00:00:00
abstract::The detection and treatment of choroidal melanoma early in its natural course is critical to providing the patient with the best prognosis. Patients with small choroidal melanoma (< 4 mm thickness) develop metastasis in 16% of cases at 5 years follow up, whereas those with medium choroidal melanoma (4-8 mm thickness) ...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-200206000-00001
更新日期:2002-06-01 00:00:00
abstract:PURPOSE OF REVIEW:The most important recent advance in the treatment of neovascular age-related macular degeneration (AMD) is the development of antivascular endothelial growth factor (anti-VEGF) therapeutic agents that preserve and improve visual acuity by arresting choroidal neovascular growth and reducing vascular p...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e32832d25b3
更新日期:2009-05-01 00:00:00
abstract:PURPOSE OF REVIEW:There have been many reports in recent literature concerning the use of scanning laser polarimetry, Heidelberg retinal tomography and optical coherence topography in assessing the optic nerve and peripapillary nerve fibre layer. It is important to assess the validity of new equipment and see whether t...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e3283112bc8
更新日期:2008-11-01 00:00:00
abstract::The possibility for visual improvement after the treatment of subfoveal choroidal neovascular membranes with laser photocoagulation is poor. The surgical excision of these membranes in age-related macular degeneration, the presumed ocular histoplasmosis syndrome, idiopathic neovascularization, and myopia is the focus ...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199306000-00004
更新日期:1993-06-01 00:00:00
abstract::An improvement in our understanding of the pathogenesis and natural history of idiopathic macular holes over the last 10 years has led to a more optimistic and interventionist approach to the surgical management of this vitreoretinal disorder. This article reviews the theories postulated for the pathogenesis of this c...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199706000-00015
更新日期:1997-06-01 00:00:00
abstract:PURPOSE OF REVIEW:The diagnosis and management of chronic pediatric uveitis can be particularly challenging, with an estimated 25-33% of childhood uveitis cases resulting in severe, life-long visual disability. This paper reviews the recent literature on the management of chronic pediatric uveitis. RECENT FINDINGS:Thi...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/01.icu.0000177414.79030.32
更新日期:2005-10-01 00:00:00
abstract:PURPOSE OF REVIEW:Glaucoma has a disproportionate prevalence among specific ethnic groups. Therefore, the issue of 'race' and glaucoma has been the focus of much discussion. The purpose of this article is to provide a review of the literature regarding the prevalence, management, and outcome of glaucoma among different...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/01.icu.0000156137.28193.48
更新日期:2005-04-01 00:00:00
abstract:PURPOSE OF REVIEW:This review summarizes the current evidence for biologic therapies in the treatment of uveitis. The review emphasizes published research in this field since 2005. RECENT FINDINGS:The anti-tumour necrosis factor-alpha infliximab and adalimumab have demonstrated significant efficacy in controlling uvei...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e3282f03d42
更新日期:2007-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Many causes of toxic optic neuropathy have been described to date and novel causes of toxicity are continuously being added to the current literature. The pathophysiological basis for the toxicity or a direct causal relationship is yet to be determined for many of these agents. This review highlights ...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000001
更新日期:2013-11-01 00:00:00
abstract:PURPOSE OF REVIEW:This review provides an update of recent advances in understanding the quality and functional significance of contrast sensitivity for the clinician regarding cataract, intraocular lenses and refractive surgery that goes beyond the measurement of visual acuity. RECENT FINDINGS:New American National S...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/01.icu.0000192520.48411.fa
更新日期:2006-02-01 00:00:00
abstract:PURPOSE OF REVIEW:Topography-guided laser refractive surgery regularizes the front corneal surface irregularities to achieve the desired refractive outcome. This is particularly applicable in highly aberrated corneas, where wavefront aberrometry is often not possible. This article aims to review the recently published ...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e3283622a59
更新日期:2013-07-01 00:00:00
abstract:PURPOSE OF REVIEW:To describe the epidemiology of disc hemorrhages and underscore the importance of detecting these markers of potential glaucomatous damage and progression. RECENT FINDINGS:The Ocular Hypertension Treatment Study has confirmed that disc hemorrhages are an independent risk factor in the development of ...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e3282f3e6bc
更新日期:2008-03-01 00:00:00
abstract::In the past year, as in recent years, most of the research on the development of refraction has focused on the following: 1) mechanisms whereby the eye can maintain coordinated growth to achieve emmetropia and 2) disruptions of emmetropization resulting in myopia or hyperopia. Preterm children and those with Down synd...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199910000-00002
更新日期:1999-10-01 00:00:00
abstract:PURPOSE OF REVIEW:Greater understanding of central serous chorioretinopathy (CSCR) has changed initial beliefs that CSCR is a benign condition affecting young men with almost complete resolution. CSCR has a spectrum of presentations with more diffuse retinal dysfunction and variations between races. CSCR can affect old...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e3283459826
更新日期:2011-05-01 00:00:00