Abstract:
:Incubation of human sperm from semen with counts below 20 x 10(6)/ml with peanut agglutinin (PNA) resulted in agglutination of about 70% of sperm. An inverse correlation was found between non-agglutinating (PNA) sperm and sperm density (r = 0.48, p less than 0.01) and a direct correlation with acrosome-damaged sperm (r = 0.83, p less than 0.001). Binding of 125I-PNA to sperm revealed high, and possibly also low affinity binding sites on sperm from both normozoospermic and oligozoospermic origins. Quantitative transmission electron microscopy analysis revealed that agglutinated, PNA+, sperm had lower frequency of acrosomeless spermatozoa than PNA(-)-sperm (44% versus 77%) and higher fertility score (+0.18 +/- 0.1 and -1.5 +/- 0.87 respectively, p less than 0.01). Removal of PNA- sperm from oligozoospermic semen may increase the fertility score of the remaining sperm.
journal_name
Andrologiajournal_title
Andrologiaauthors
Ravid A,Sagiv M,Bartoov B,Eltes F,Novogrodsky A,Allalouf D,Levinsky H,Singer Rdoi
10.1111/j.1439-0272.1990.tb01970.xsubject
Has Abstractpub_date
1990-05-01 00:00:00pages
225-30issue
3eissn
0303-4569issn
1439-0272journal_volume
22pub_type
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