Separation of sub-populations of sperm with higher fertility potential from normal and pathological semen by peanut agglutinin.

Abstract:

:Incubation of human sperm from semen with counts below 20 x 10(6)/ml with peanut agglutinin (PNA) resulted in agglutination of about 70% of sperm. An inverse correlation was found between non-agglutinating (PNA) sperm and sperm density (r = 0.48, p less than 0.01) and a direct correlation with acrosome-damaged sperm (r = 0.83, p less than 0.001). Binding of 125I-PNA to sperm revealed high, and possibly also low affinity binding sites on sperm from both normozoospermic and oligozoospermic origins. Quantitative transmission electron microscopy analysis revealed that agglutinated, PNA+, sperm had lower frequency of acrosomeless spermatozoa than PNA(-)-sperm (44% versus 77%) and higher fertility score (+0.18 +/- 0.1 and -1.5 +/- 0.87 respectively, p less than 0.01). Removal of PNA- sperm from oligozoospermic semen may increase the fertility score of the remaining sperm.

journal_name

Andrologia

journal_title

Andrologia

authors

Ravid A,Sagiv M,Bartoov B,Eltes F,Novogrodsky A,Allalouf D,Levinsky H,Singer R

doi

10.1111/j.1439-0272.1990.tb01970.x

subject

Has Abstract

pub_date

1990-05-01 00:00:00

pages

225-30

issue

3

eissn

0303-4569

issn

1439-0272

journal_volume

22

pub_type

杂志文章
  • Control of gonadotropin secretion in prepubertal male rats by excitatory amino acids.

    abstract::The role of N-methyl-D-aspartate (NMDA) and non-NMDA receptors in the control of FSH and LH secretion was analysed in prepubertal male rats. In the first experiment 4, 8, 12, 16, 20 and 30-day-old males were decapitated 15 min after vehicle, NMDA or kainic acid (KA) administration. In the second experiment, 23-day-old...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1996.tb02776.x

    authors: Aguilar E,Tena-Sempere M,Gonzalez D,Pinilla L

    更新日期:1996-05-01 00:00:00

  • The antiapoptotic and antioxidant effects of eugenol against cisplatin-induced testicular damage in the experimental model.

    abstract::Testicular dysfunction or damage is among the critical side effects of chemotherapeutic drugs like cisplatin. This study was mapped out to assess the possible therapeutic effect of eugenol on cisplatin-induced testicular damage. In this experimental study, a single dose of cisplatin (15 mg/kg) was given intraperitonea...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.13353

    authors: Ekinci Akdemir FN,Yildirim S,Kandemir FM,Aksu EH,Guler MC,Kiziltunc Ozmen H,Kucukler S,Eser G

    更新日期:2019-10-01 00:00:00

  • A case of proximal partial priapism successfully treated with autologous clot embolisation.

    abstract::Partial priapism is a rare disorder in literature and generally described as a contusion or thrombosis of the cavernous body of the penis secondary to blunt trauma. Because of the rarity of disease, there is not much information about the treatment. Conservative management with nonsteroidal anti-inflammatory drug is o...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.13510

    authors: Ozden S,Yildirim O,Ozbek E,Gulsen F

    更新日期:2020-04-01 00:00:00

  • Isolation method of Leydig cells from mature male Djungarian hamsters (Phodopus sungorus) and their steroidogenic activity in vitro.

    abstract::For studies addressing the functions of Leydig cells, isolated cells are often better suited than intact animals. Here, the isolation procedure of Leydig cells from adult male Djungarian hamsters (Phodopus sungorus) is described. Cells were isolated using a procedure involving enzymatic dissociation and Percoll-gradie...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:

    authors: Niedziela M,Lerchl A

    更新日期:1999-05-01 00:00:00

  • Testosterone, FSH and LH in human spermatic and cubital venous plasma in varicocele patients.

    abstract::The plasma level of testosterone, FSH and LH were determined simultaneously in spermatic and cubital veins in 12 patients with varicocele. The testosterone levels in spermatic veins were 13.4 +/- 5.3 times higher than in cubital veins. FSH and LH levels were higher in cubital than in spermatic vein. No correlation was...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1985.tb01018.x

    authors: Bablok L,Janczewski Z,Czaplicki M

    更新日期:1985-07-01 00:00:00

  • Correlation of biochemical constituents of seminal plasma with semen quality in Teddy goat (Capra hircus) bucks.

    abstract::This study was planned to determine the relationship between semen quality parameters and the levels of biochemical constituents of seminal plasma of Teddy (Capra hircus) buck semen. For this purpose, semen ejaculates were collected from five mature healthy Teddy bucks. All the experimental bucks were kept under natur...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.12940

    authors: Umar S,Ahmad M,Ahmad I,Zubair M,Umar Z,Qureshi AS,Manzoor A,Murtaza A,Shaukat A

    更新日期:2018-04-01 00:00:00

  • Association between lower urinary tract symptoms and sexual dysfunction in Taiwanese men.

    abstract::The study investigated the association between lower urinary tract symptoms (LUTS) and sexual dysfunction in ageing men. It was a cross-sectional study in an unselected consecutive sample of 398 men aged >40 years attending a urology clinic. LUTS and sexual function were assessed by validated symptom scales, including...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.2008.00876.x

    authors: Tsao CW,Cha TL,Lee SS,Tang SH,Wu ST,Tsui KH,Sun GH

    更新日期:2008-12-01 00:00:00

  • Novel predictive risk factor for Erectile Dysfunction: Serum folic acid.

    abstract::The purpose of this study was to compare the serum Folic Acid (FA) levels in patients with Erectile Dysfunction (ED) and healthy controls and whether levels vary with its severity. The study was carried out on 77 sexually active individuals, out of which 41 complained of ED and 36 were apparently normal. Patients were...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.13890

    authors: Gupta A,Priyadarshi S,Vyas N,Sharma G,Swain PK

    更新日期:2021-02-01 00:00:00

  • Automated semen analysis by SQA Vision® versus the manual approach-A prospective double-blind study.

    abstract::Next to clinical investigations, the evaluation of male fertility relies mainly on detailed sperm analyses, for example, cell counting, motility, cell morphology and vitality testing. The manual creation of a spermiogram is time- and material-consuming. Therefore, reliable high-throughput systems that may be substitut...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.13149

    authors: Engel KM,Grunewald S,Schiller J,Paasch U

    更新日期:2019-02-01 00:00:00

  • Male breast cancer--an andrological disease: risk factors and diagnosis.

    abstract::Gynaecomastia, the enlargement of the male breast, is considered as an andrological disease. To date, a review on male breast cancer (MBC) has not been published in an andrological journal. The papers underlying this review were published from authors of different institutions: Clinical Genetics, Dermatology, Gynaecol...

    journal_title:Andrologia

    pub_type: 杂志文章,评审

    doi:10.1111/j.1439-0272.2004.00639.x

    authors: Krause W

    更新日期:2004-12-01 00:00:00

  • [Motivation and compliance of andrology patents].

    abstract::150 randomized patients from the andrology department of the University Hospital for Gynecology and Obstetrics, Graz, Austria have been evaluated concerning their motivation, cooperation and compliance. To gain basic data from andrology patients and to analyze consequences after the first clinical examination was one ...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:

    authors: Pusch HH

    更新日期:1985-03-01 00:00:00

  • Primary seminal vesicle adenocarcinoma: A case report of rare entity and discussion of its differential diagnosis using immunohistochemical approach for the core biopsy specimen.

    abstract::Primary seminal vesicle adenocarcinoma is a rare malignancy of the male genito-urinary system with only a few confirmed reported cases. Initial tissue diagnostic modality is often a core biopsy specimen. Here, we report this rare entity in a 50-year-old male, highlighting the histomorphological and immunohistochemical...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.13512

    authors: Bhardwaj N,Rastogi P,Attri VS,Bora GS,Gorsi U

    更新日期:2020-04-01 00:00:00

  • Leydig cell function and morphology in the rat testis after exposure to heat.

    abstract::Leydig cell function, as judged from testosterone concentrations in plasma and in testicular tissue after LH stimulation, was tested in adult rat testes 4 days after brief exposure of the scrotum to 33 degrees and 43 degrees C, respectively. There was no significant difference in basal plasma testosterone concentratio...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1980.tb00568.x

    authors: Damber JE,Bergh A,Janson PO

    更新日期:1980-01-01 00:00:00

  • The effects of different dietary protein sources on live weight, sperm quality and the histology of the testes and accessory glands in male rats.

    abstract::This study was aimed at determining the effects of corn and wheat gluten, used as dietary protein sources, on live weight gain, sperm quality and the histology of the testes and accessory glands in male rats. For this purpose, 20-day-old 24 male Wistar albino rats were randomly assigned to three groups. Group 1 (Contr...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.13601

    authors: Gumus R,Uslu S,Uslu BA

    更新日期:2020-07-01 00:00:00

  • Management of supernumerary testis in an adult: case report and review.

    abstract::Polyorchidism is a rare congenital anomaly. Approximately 100 cases have been published to date. We report a case of triorchidism in a 20-year-old man who presented to us with inguinal hernia. There is more than 30% incidence of histological abnormalities in polyorchid testes and 4-7% present with malignancy. The mana...

    journal_title:Andrologia

    pub_type: 杂志文章,评审

    doi:10.1111/j.1439-0272.2009.01026.x

    authors: Nayak SP,Sreejayan MP

    更新日期:2011-04-01 00:00:00

  • Antioxidant effects of N-acetylcysteine on the male reproductive system: A systematic review.

    abstract::This study aimed to evaluate the effect of N-acetyl cysteine on the male reproductive system and consensus and classification of data found from previous studies. It is undeniable that N-acetyl cysteine as a powerful antioxidant compound can medicate many diseases such as cardiovascular, kidney, liver and reproductive...

    journal_title:Andrologia

    pub_type: 杂志文章,评审

    doi:10.1111/and.13898

    authors: Ghafarizadeh A,Malmir M,Naderi Noreini S,Faraji T

    更新日期:2021-02-01 00:00:00

  • Effect of nonylphenol on spermatogenesis: A systematic review.

    abstract::Nonylphenol (NP) is known as an environmental pollutant that has adverse effects on the spermatogenesis process. In this review, we focus on (1999-2020) studies on the effect of this pollutant on the sperm parameters and the male reproductive system. Spermatogenesis is a process in which male spermatogonia (primary ge...

    journal_title:Andrologia

    pub_type: 杂志文章,评审

    doi:10.1111/and.13748

    authors: Malmir M,Faraji T,Ghafarizadeh AA,Khodabandelo H

    更新日期:2020-07-14 00:00:00

  • Effects of a DNA-specific fluorochrome, Hoechst 33258, on mouse sperm motility and fertilizing capacity.

    abstract::DNA specific fluorochrome (Hoechst 33342 and 33258) as non-toxic stains, have been widely used to measure cell density and proliferation, detect sperm-egg fusion, and observe the development of pre-implantation embryos. It has been reported that Hoechst 33342 at a concentration of 10 micrograms ml-1 had significant in...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1992.tb02632.x

    authors: Yelian FD,Dukelow WR

    更新日期:1992-05-01 00:00:00

  • Functional characterisation of a natural androgen receptor missense mutation (N771H) causing human androgen insensitivity syndrome.

    abstract::Androgen insensitivity syndrome (AIS) is an X-linked disorder due to mutations of androgen receptor (AR) gene. Various AR mutations have been identified, and the characterisation of these mutations greatly facilitates our understanding of AR structure-function. In this study, we have analysed an AR missense mutation (...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.2011.01219.x

    authors: Cai J,Cai LQ,Hong Y,Zhu YS

    更新日期:2012-05-01 00:00:00

  • Seminal parameters of chronic male genital inflammation are associated with disturbed sperm DNA integrity.

    abstract::Definition of chronic male genital tract inflammation and its impact on male infertility is still a matter of debate. In particular, DNA integrity has been reported to be disturbed in subfertile men. Thus, the aim of this study was to investigate an association of DNA integrity to altered standard semen parameters as ...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.12408

    authors: Haidl F,Haidl G,Oltermann I,Allam JP

    更新日期:2015-05-01 00:00:00

  • Pulmonary embolism complicating human chorionic gonadotropin treatment in a patient with type IV hyperlipoproteinemia.

    abstract::Human chorionic Gonadotropin (HCG) therapy has been used beneficially in men with subfertility especially after varicocele surgery. Very few side effects have been observed in male patients. Herein, we report a case of pulmonary embolism in a male patient following the use of HCG. The patient was subsequently found to...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1987.tb01861.x

    authors: Dhabuwala CB,Kumar A,Pierce JM

    更新日期:1987-01-01 00:00:00

  • The presence of progressive motility sustaining factor (PMSF) in human epididymis.

    abstract::Progressive Motility Sustaining Factor (PMSF) was isolated from human epididymides. PMSF could significantly improve progressive motility of oligozoospermic as well as asthenozoospermic semen. PMSF was found to increase cyclic AMP accumulation by the human spermatozoa indicating its possible mode of action. ...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1981.tb00021.x

    authors: Sheth AR,Gunjikar AN,Shah GV

    更新日期:1981-03-01 00:00:00

  • Treatment of oligozoospermia with tamoxifen (open and controlled studies).

    abstract::Open and double-blind therapeutic studies were carried out on the effects of tamoxifen in oligozoospermia. The examinations involved 74 patients. The first group (n = 20) received tamoxifen 20 mg/day; the second group (n = 54) got tamoxifen or placebo for 3 months. In the open study, tamoxifen treatment led to signifi...

    journal_title:Andrologia

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1439-0272.1985.tb01048.x

    authors: Török L

    更新日期:1985-09-01 00:00:00

  • The effects of vasectomy on viscosity, pH and volume of semen in man.

    abstract::The effects of vasectomy on seminal viscosity, volume and pH have been investigated in freshly emitted semen of 21 healthy men before operation and three months later. Viscosity and the pH range were decreased significantly, but the decrease of the seminal volume was not significant. Reasons of changes have been discu...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1979.tb02170.x

    authors: Nikkanen V

    更新日期:1979-03-01 00:00:00

  • Nuclear sperm quality in total polymorphic teratozoospermia and its impact on intracytoplasmic sperm injection outcome.

    abstract::Various nuclear sperm alterations are reported in patients with syndromic teratozoospermia; however, this has not been clearly identified yet in total polymorphic teratozoospermia. The aim of this study was to analyse sperm aneuploidy, DNA integrity and chromatin packaging in 45 infertile patients with total polymorph...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.13252

    authors: Braham A,Ghedir H,Zidi I,Sallem A,Hajlaoui A,Ajina M,Saad A,Ibala-Romdhane S

    更新日期:2019-06-01 00:00:00

  • Reproductive immunology: 4. The effect of seminal plasma from immunologic infertile men on in vitro lymphocyte cultures.

    abstract::The seminal plasma of 31 patients were examined for the presence of sperm antibodies and for inhibitory properties on the transformation rates of donor lymphocytes cultured in vitro. Twenty five (80%) of the men revealed apart from fertile semen, no sperm antibody activities while six (20%) patients showed high sperma...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1982.tb03105.x

    authors: Franken DR,Slabber CF

    更新日期:1982-03-01 00:00:00

  • Polyorchidism with varicocele: a case report and review of literature.

    abstract::Polyorchidism is defined as the presence of more than 2 histologically proven testes. We report the case of a 20-year-old man with polyorchidism, presenting with right scrotal pain and right scrotal ovoid mass. Scrotal examination revealed two ovoid, mobile lumps with testicular sensation in the right side of the scro...

    journal_title:Andrologia

    pub_type: 杂志文章,评审

    doi:10.1111/j.1439-0272.2011.01205.x

    authors: Topsakal K,Ak H,Yumurtas N

    更新日期:2012-05-01 00:00:00

  • The evaluation of free-L-carnitine, zinc and fructose in the seminal plasma of patients with varicocele and normozoospermia.

    abstract::The function of the epididymis and of the sex accessory glands have been investigated in a selected group of varicocele patients with normal sperm count. In the seminal plasma of these patients free-L-carnitine, fructose and zinc levels were determined as functional markers respectively of epididymis, seminal vesicles...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:

    authors: Andó S,Carpino A,Buffone M,Maggiolini M,Sisci D

    更新日期:1989-03-01 00:00:00

  • Male fertility preservation-Methods, indications and challenges.

    abstract::Male fertility preservation has been steadily increasing over the past two decades. Significant improvements have been achieved in the treatment modalities of cancer and other severe chronic medical conditions, leading to an increase in patient survivorship and the resulting demand for future parenthood. Recognition a...

    journal_title:Andrologia

    pub_type: 杂志文章,评审

    doi:10.1111/and.13635

    authors: Grin L,Girsh E,Harlev A

    更新日期:2020-05-11 00:00:00

  • Hypotonic challenge reduces human sperm motility through coiling and folding of the tail.

    abstract::Human ejaculates collected for in vitro procedures show variably rapid increases in osmolality, depending on enzymatic degradation of compounds. Changes in osmolality can affect cell functions due to the energy consuming processes needed to control cell volume. The aim was to examine the effects of a hypotonic challen...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.13859

    authors: Holmes E,Björndahl L,Kvist U

    更新日期:2020-12-01 00:00:00