Glycyrrhizin attenuates HMGB1-induced hepatocyte apoptosis by inhibiting the p38-dependent mitochondrial pathway.

abstract：:This paper reviews the progress made in understanding the mechanical behaviour of the biliary system. Gallstones and diseases of the biliary tract affect more than 10% of the adult population. The complications of gallstones, i.e. acute pancreatitis and obstructive jandice, can be lethal, and patients with acalculous ...

journal_title：World journal of gastroenterology

authors： Luo X,Li W,Bird N,Chin SB,Hill NA,Johnson AG

更新日期：2007-03-07 00:00:00

abstract：AIM:To investigate the effects of exogenously mutated p27(kipl) (p27) on proliferation and apoptosis of human cholangiocarcinoma cell line, QBC(939)in vivo. METHODS:Adenviral vectors were used to transfect mutated p27 cDNA into human QBC(939)cell line. Expression of p27 was detected by RT-PCR. Western blot. Cell growt...

journal_title：World journal of gastroenterology

authors： Luo J,Chen YJ,Wang WY,Zou SQ

更新日期：2008-09-14 00:00:00

abstract：AIM:To systematically investigate if cGMP/cGMP-dependent protein kinase G (PKG) signaling pathway may participate in dendroaspis natriuretic peptide (DNP)-induced relaxation of gastric circular smooth muscle. METHODS:The content of cGMP in guinea pig gastric antral smooth muscle tissue and perfusion solution were meas...

journal_title：World journal of gastroenterology

authors： Cai CY,Cai ZX,Gu XY,Shan LJ,Wang YX,Yin XZ,Qi QH,Guo HS

更新日期：2008-09-21 00:00:00

abstract：AIM:To investigate the prevalence of celiac disease (CD) in adult patients referred to an open access gastroenterology clinic in the south of Italy and submitted to esophago-gastro-duodenoscopy (EGD) for evaluation of refractory functional dyspepsia. METHODS:Seven hundred and twenty six consecutive dyspeptic patients ...

journal_title：World journal of gastroenterology

authors： Giangreco E,D'agate C,Barbera C,Puzzo L,Aprile G,Naso P,Bonanno G,Russo FP,Nicoletti A,Incarbone S,Trama G,Russo A

更新日期：2008-12-07 00:00:00

abstract：:Despite substantial efforts at early diagnosis, accurate staging and advanced treatments, esophageal cancer (EC) continues to be an ominous disease worldwide. Risk factors for esophageal carcinomas include obesity, gastroesophageal reflux disease, hard-alcohol use and tobacco smoking. Five-year survival rates have imp...

journal_title：World journal of gastroenterology

authors： DaVee T,Ajani JA,Lee JH

更新日期：2017-02-07 00:00:00

abstract：AIM:To investigate omeprazole-induced transepithelial gastric leak and its effects on the permeability of the peptides bradykinin and oxytocin. METHODS:Rat gastric corpus tissue was isolated and mounted in an Ussing chamber apparatus to evaluate the permeability of (3)H-bradykinin, (3)H-oxytocin, and (14)C-EDTA in the...

journal_title：World journal of gastroenterology

authors： Gabello M,Valenzano MC,Zurbach EP,Mullin JM

更新日期：2010-03-07 00:00:00

abstract：AIM:To evaluate the ability of endoscopic ultrasound (EUS) elastography to distinguish benign from malignant pancreatic masses and lymph nodes. METHODS:A multicenter study was conducted and included 222 patients who underwent EUS examination with assessment of a pancreatic mass (n = 121) or lymph node (n = 101). The c...

journal_title：World journal of gastroenterology

authors： Giovannini M,Thomas B,Erwan B,Christian P,Fabrice C,Benjamin E,Geneviève M,Paolo A,Pierre D,Robert Y,Walter S,Hanz S,Carl S,Christoph D,Pierre E,Jean-Luc VL,Jacques D,Peter V,Andrian S

更新日期：2009-04-07 00:00:00

abstract：:AIM:To construct Hsp90 antisense RNA eukaryotic expression vector, transfect it into SGC7901 and SGC7901/VCR of MDR-type human gastric cancer cell lines, HCC7402 of human hepatic cancer and Ec109 of human esophageal cancer cell lines, and to study the cell cycle distribution of the gene transected cells and their resp...

journal_title：World journal of gastroenterology

authors： Liu XL,Xiao B,Yu ZC,Guo JC,Zhao QC,Xu L,Shi YQ,Fan DM

更新日期：1999-06-01 00:00:00

abstract：AIM:To investigate the safety and feasibility of needlescopic grasper-assisted single-incision laparoscopic common bile duct exploration (nSIL-CBDE) by comparing the surgical outcomes of this technique with those of conventional laparoscopic CBDE (CL-CBDE). METHODS:We retrospectively analyzed the clinical data of pati...

journal_title：World journal of gastroenterology

authors： Kim SJ,Kim KH,An CH,Kim JS

更新日期：2015-12-07 00:00:00

abstract：AIM:To determine the clinical effectiveness of intense psychological support to physical activity (PA) in nonalcoholic fatty liver disease (NAFLD), compared with cognitive-behavioral treatment (CBT). METHODS:Twenty-two NAFLD cases received support to exercise, tailored to their motivational needs (PA group). The effec...

journal_title：World journal of gastroenterology

authors： Montesi L,Caselli C,Centis E,Nuccitelli C,Moscatiello S,Suppini A,Marchesini G

更新日期：2014-08-07 00:00:00

abstract：:Arthrogryposis, renal dysfunction and cholestasis (ARC) syndrome (OMIM 208085) is an autosomal recessive disorder that is caused by mutations in 2 interacting genes VPS33B and VIPAS39. Mutations in VPS33B gene account for most cases of ARC. As low or normal gamma-glutamyl transpeptidase (GGT) activity has been describ...

journal_title：World journal of gastroenterology

authors： Wang JS,Zhao J,Li LT

更新日期：2014-04-28 00:00:00

abstract：AIM:To investigate GATA5, SFRP2, and ITGA4 methylation in plasma DNA as noninvasive biomarkers for colorectal cancer (CRC) or adenomas. METHODS:There were 57 CRC patients, 30 adenomas patients, and 47 control patients enrolled in this study. Methylation-specific polymerase chain reaction was used to determine the prom...

journal_title：World journal of gastroenterology

authors： Zhang X,Song YF,Lu HN,Wang DP,Zhang XS,Huang SL,Sun BL,Huang ZG

更新日期：2015-03-07 00:00:00

abstract：:Percutaneous ablation using thermal or chemical methods has been widely used in the treatment of hepatocellular carcinoma (HCC). Nowadays, contrast-enhanced imaging modalities such as computed tomography (CT), magnetic resonance imaging (MRI), and contrast-enhanced ultrasound (CEUS) are widely used to evaluate local t...

journal_title：World journal of gastroenterology

authors： Liu LN,Xu HX,Zhang YF,Xu JM

更新日期：2013-02-14 00:00:00

abstract：AIM:To evaluate the predictive value of tissue transglutaminase (tTG) antibodies for villous atrophy in adult and pediatric populations to determine if duodenal biopsy can be avoided. METHODS:A total of 324 patients with celiac disease (CD; 97 children and 227 adults) were recruited prospectively at two tertiary cente...

journal_title：World journal of gastroenterology

authors： Vivas S,Ruiz de Morales JG,Riestra S,Arias L,Fuentes D,Alvarez N,Calleja S,Hernando M,Herrero B,Casqueiro J,Rodrigo L

更新日期：2009-10-14 00:00:00

abstract：:Tumor necrosis factor-α (TNF-α) inhibitors are known to increase reactivation of concurrent chronic hepatitis B, but their impact on the hepatitis C virus (HCV) is controversial. Some conditions of immunosuppression, such as liver transplantation, typically cause an increase in the rate of HCV evolution. Inhibition of...

journal_title：World journal of gastroenterology

authors： Pompili M,Biolato M,Miele L,Grieco A

更新日期：2013-11-28 00:00:00

abstract：:A 46-year-old female patient with terminal ileum Crohn's disease and ankylosing spondylitis presented with recurrent angioedema and urticaria. Investigations ruled out hereditary angioedema, and environmental or food allergen triggers. She was diagnosed with chronic idiopathic urticaria with angioedema, and was treate...

journal_title：World journal of gastroenterology

authors： Habal F,Huang V

更新日期：2012-09-14 00:00:00

abstract：AIM:To investigate the safety and efficacy of the formulation HD-03/ES capsules in the management of patients with chronic hepatitis B infection. METHODS:A total of 25 patients were recruited to the study and were given HD-03/ES, two capsules twice daily for six months. Clinical assessment of symptoms and signs were d...

journal_title：World journal of gastroenterology

authors： Rajkumar JS,Sekar MG,Mitra SK

更新日期：2007-08-14 00:00:00

abstract：AIM:Hepatitis B virus (HBV) re-activation often occurs spontaneously or after withdrawal of immunosuppressive therapy in patients with chronic hepatitis B. Severe exacerbation, sometimes developing into fulminant hepatic failure, is at high risk of mortality. The efficacy of corticosteroid therapy in "clinically severe...

journal_title：World journal of gastroenterology

authors： Fujiwara K,Yokosuka O,Kojima H,Kanda T,Saisho H,Hirasawa H,Suzuki H

更新日期：2005-02-28 00:00:00

abstract：:Pelvic radiation is a commonly utilized treatment for malignancy of the genitourinary and lower gastrointestinal tract. Radiation proctitis and the resultant clinical picture varies from asymptomatic to potentially life threatening. Similarly, treatment options also vary greatly, from medical therapy to surgical inter...

journal_title：World journal of gastroenterology

authors： Weiner JP,Wong AT,Schwartz D,Martinez M,Aytaman A,Schreiber D

更新日期：2016-08-21 00:00:00

abstract：AIM:To study the beneficial effects of triterpene alpha,beta-amyrin and the underlying mechanisms in an experimental pancreatitis model. METHODS:Acute pancreatitis was induced in five groups of rats (n = 8) by L-arginine (2 x 2.5 g/kg, intraperitoneal, 1 h apart) and 1 h later, they received a single oral dose of alph...

journal_title：World journal of gastroenterology

authors： Melo CM,Carvalho KM,Neves JC,Morais TC,Rao VS,Santos FA,Brito GA,Chaves MH

更新日期：2010-09-14 00:00:00

abstract：:A number of alterations have been found within the gut microbial profile of patients with inflammatory bowel diseases when compared with the healthy population; however, it is unclear whether such dysbiosis is the cause or simply the consequence of the disease state. In ulcerative colitis, the environment seems to pla...

journal_title：World journal of gastroenterology

authors： Sorrentino D

更新日期：2017-10-07 00:00:00

abstract：BACKGROUND:It is unclear whether immune escape-associated mutations in the major hydrophilic region of hepatitis B virus surface antigen (HBsAg) are associated with nucleoside/nucleotide analog resistance. AIM:To evaluate the association between immune escape-associated mutations and nucleoside/nucleotide analog resis...

journal_title：World journal of gastroenterology

authors： Huang BX,Liu Y,Fan ZP,Si LL,Chen RJ,Wang J,Luo D,Wang FS,Xu DP,Liu XG

更新日期：2020-09-21 00:00:00

abstract：:The main treatment of patients with non-alcoholic fatty liver disease (NAFLD) is life style modification including weight reduction and dietary regimen. Majority of patients are safely treated with this management and pharmacologic interventions are not recommended. However, a subgroup of NAFLD patients with non-alcoh...

journal_title：World journal of gastroenterology

authors： Eshraghian A

更新日期：2017-11-14 00:00:00

abstract：:The combination of either boceprevir or telaprevir with ribavirin and interferon (triple therapy) has been shown to be more effective than ribavirin+interferon (dual therapy) for the treatment of genotype 1 hepatitis C. Since the benefit of these treatments takes place after years, simulation models are needed to pred...

journal_title：World journal of gastroenterology

authors： Messori A,Fadda V,Maratea D,Trippoli S

更新日期：2012-06-21 00:00:00

abstract：AIM:To examine the expressions of matrix metalloproteinases-2 (MMP-2) and tissue inhibitor of metalloproteinases-1 (TIMP-1) in rat fibrotic liver and in normal rat hepatic stellate cells, and to investigate the changes in their expressions in response to treatment with interleukin-10 (IL-10) and platelet-derived growth...

journal_title：World journal of gastroenterology

authors： Zhang LJ,Chen YX,Chen ZX,Huang YH,Yu JP,Wang XZ

更新日期：2004-09-01 00:00:00

abstract：:Wireless capsule endoscopy (CE) is a technology developed for the endoscopic exploration of the small bowel. The first capsule model was approved by the Food and Drug Administration in 2001, and its first and essential indication was occult gastrointestinal (GI) bleeding. Over subsequent years, this technology has bee...

journal_title：World journal of gastroenterology

authors： Redondo-Cerezo E,Sánchez-Capilla AD,De La Torre-Rubio P,De Teresa J

更新日期：2014-11-14 00:00:00

abstract：:AIM:To infect mice with Helicobacter pylori and detect immune response against two form of H. pylori.METHODS:An isolate of H. pylori obtained from a patient with gastric cancer was used to infect mice. Fifty mice were divided into eight groups. Two groups served as negative control without any inoculation and internal...

journal_title：World journal of gastroenterology

authors： Hua JS,Bow H,Zheng PY,Yeoh GK,Ng CH,Lim GS

更新日期：1998-12-01 00:00:00

abstract：AIM:To clarify whether serum chemokine and cytokine levels can become useful biological and functional markers to assess the severity of chronic pancreatitis (CP). This study aimed at clarifying whether serum chemokine and cytokine levels can become useful biological and functional markers to assess the severity of CP....

journal_title：World journal of gastroenterology

authors： Yasuda M,Ito T,Oono T,Kawabe K,Kaku T,Igarashi H,Nakamura T,Takayanagi R

更新日期：2008-11-14 00:00:00

abstract：:Small cell neuroendocrine carcinoma of the ampulla of Vater is extremely rare and different from the common ampullary adenocarcinoma. The ampullary adenoma is also a rare neoplasm and has the potential to develop an adenocarcinoma. Their coexistence has been rarely reported in the literature. We herein describe an unu...

journal_title：World journal of gastroenterology

authors： Sun JH,Chao M,Zhang SZ,Zhang GQ,Li B,Wu JJ

更新日期：2008-08-07 00:00:00

abstract：:Malignant gastrointestinal stromal tumors (GIST) are rare mesenchymal tumors originating from the wall of the gastrointestinal tract. Their coexistence with other tumors originating from other germ layers is unique. We have reported a case of a 63-year-old GIST patient presenting as an epigastric mass associated with ...

journal_title：World journal of gastroenterology

authors： Jaworski R,Jastrzebski T,Swierblewski M,Drucis K,Kobierska-Gulida G

更新日期：2006-01-28 00:00:00