Spread of onabotulinumtoxinA after bladder injection. Experimental study using the distribution of cleaved SNAP-25 as the marker of the toxin action.

abstract：BACKGROUND:The endothelin-A receptor (ETAR) has been implicated in the progression of prostate cancer. OBJECTIVES:To investigate the safety and efficacy of the specific ETAR antagonist ZD4054 in patients with metastatic hormone-resistant prostate cancer (HRPC). DESIGN, SETTING, AND PARTICIPANTS:Double-blind, placebo-...

journal_title：European urology

authors： James ND,Caty A,Borre M,Zonnenberg BA,Beuzeboc P,Morris T,Phung D,Dawson NA

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Bladder pain syndrome/interstitial cystitis (BPS/IC) is a chronic disease without an effective treatment, characterized by pain during bladder filling. Most nociceptive bladder afferents course in the trigone. OBJECTIVE:To evaluate efficacy and tolerability of trigonal injection of botulinum toxin A (BoNTA)...

journal_title：European urology

authors： Pinto R,Lopes T,Frias B,Silva A,Silva JA,Silva CM,Cruz C,Cruz F,Dinis P

更新日期：2010-09-01 00:00:00

abstract：CONTEXT:Radiolabelled choline positron emission tomography has changed the management of prostate cancer patients. However, new emerging radiopharmaceutical agents, like radiolabelled prostate specific membrane antigen, and new promising hybrid imaging will begin new challenges in the diagnostic field. OBJECTIVE:The c...

journal_title：European urology

authors： Evangelista L,Briganti A,Fanti S,Joniau S,Reske S,Schiavina R,Stief C,Thalmann GN,Picchio M

更新日期：2016-07-01 00:00:00

abstract：:Treatment of localized prostate cancer by ultrasonically guided transperineal 125I implantation, in contrast to open 125I implantation, may allow for ideal distribution of the seeds and may therefore lead to better treatment results. 46 patients with localized prostatic carcinoma (T1-T2, G1-G3, N0, M0) have been treat...

journal_title：European urology

authors： Vijverberg PL,Kurth KH,Blank LE,Dabhoiwala NF,de Reijke TH,Koedooder K

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To describe the clinical characteristics and treatment results obtained with the application of a homogeneous treatment protocol in 1490 patients with germ-cell tumours (GCT) registered in the 55 hospitals belonging to the Spanish Germ-Cell Cancer Group (GG) during the period between January 1994 and April 20...

journal_title：European urology

authors： Germà-Lluch JR,Garcia del Muro X,Maroto P,Paz-Ares L,Arranz JA,Gumà J,Alba E,Sastre J,Aparicio J,Fernández A,Barnadas A,Terrassa J,Sáenz A,Almenar D,López-Brea M,Climent MA,Sánchez MA,Lasso de la Vega R,Berenguer G,

更新日期：2002-12-01 00:00:00

abstract：:Successful sexual functioning is a complex process involving psychological and social responses as well as neurological, biochemical and vascular processes. Today it is believed that more than 50% of the sexual dysfunction cases have an organic etiology. Reflecting the controversy over the management of psychogenic im...

journal_title：European urology

authors： Yaman LS,Kiliç S,Sarica K,Bayar M,Saygin B

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVES:The script concordance (SC) test is designed to measure the organisation of knowledge that allows interpretation of data in clinical reasoning. This study explores the use of this new written examination tool in urology. MATERIALS AND METHODS:An 80 items SC test was administered to participants from a Frenc...

journal_title：European urology

authors： Sibert L,Charlin B,Corcos J,Gagnon R,Lechevallier J,Grise P

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Urethrorectal fistulas (URF) in patients with complex posterior urethral strictures are rare and difficult to repair surgically. There is no widely accepted standard approach described in the published literature. OBJECTIVE:The aim of this study was to describe the outcomes of various operative approaches f...

journal_title：European urology

authors： Xu YM,Sa YL,Fu Q,Zhang J,Jin SB

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:The survival impact of metastasectomy for metastatic renal cell carcinoma (mRCC) is still an active research field, particularly in the multimodal/targeted therapy era. OBJECTIVE:To determine the survival impact of clinical prognostic factors and their application to stratification of patients according to ...

journal_title：European urology

authors： Tosco L,Van Poppel H,Frea B,Gregoraci G,Joniau S

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Incontinence has a greater detrimental effect on quality of life than other symptoms of overactive bladder (OAB) and is often difficult to treat with antimuscarinic monotherapy. OBJECTIVE:To evaluate the efficacy and the safety and tolerability of combination (solifenacin 5mg and mirabegron 50mg) versus sol...

journal_title：European urology

authors： Drake MJ,Chapple C,Esen AA,Athanasiou S,Cambronero J,Mitcheson D,Herschorn S,Saleem T,Huang M,Siddiqui E,Stölzel M,Herholdt C,MacDiarmid S,BESIDE study investigators.

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to evaluate the role of p53 immunoreactivity as a prognostic marker in prostate cancer. METHODS:The nuclear accumulation of the aberrant p53 protein was determined by immunohisto-chemistry on surgical specimens and related to stage, grade and cancer-specific survival in 186 p...

journal_title：European urology

authors： Stattin P,Bergh A,Karlberg L,Nordgren H,Damber JE

更新日期：1996-01-01 00:00:00

abstract：:Signet ring cell adenocarcinoma of the bladder is rare. Only 16 cases are recorded in the literature, although two meet the requirements for being considered of urachal origin. We present the third case of signet cell adenocarcinoma of urachal origin. ...

journal_title：European urology

authors： Alonso-Gorrea M,Mompo-Sanchis JA,Jorda-Cuevas M,Froufe A,Jiménez-Cruz JF

更新日期：1985-01-01 00:00:00

abstract：:A total of 181 prostatic cancer patients under radiation monotherapy were tested for the therapeutic effect of pelvic lymphadenectomy (PLA). Sixty-seven belonging to the pN0 category formed a highly selective group and presented a 89% rate of 7-year survival. Localized radiation therapy with pelvic irradiation (81 pat...

journal_title：European urology

authors： Schubert J,Kelly LU,Wehnert J,Moravek P

更新日期：1988-01-01 00:00:00

abstract：:23 medical faculties exist in Turkey at the moment and 2 others are being established. Considering that all these faculties run their own programs independently, different education systems might effect the standard of doctors and health care. All of the new graduates in this country face a centralized examination for...

journal_title：European urology

authors： Akdaş A,Simşek F,Ilker Y

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVES:TIMPs control the activity of MMPs, one of the key molecules for tumor invasion and metastasis. The aim of this study was to assess the usefulness of MMP-2 and MMP-9 in relation to their inhibitor (TIMP2) as noninvasive diagnostic tests for bilharzial bladder cancer. MATERIAL AND METHODS:Voided urine sample...

journal_title：European urology

authors： Eissa S,Ali-Labib R,Swellam M,Bassiony M,Tash F,El-Zayat TM

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the effect of long-term sitting on serum prostate-specific antigen (PSA) levels. METHOD:The serum PSA levels of 50 bus drivers under the age of 45 (mean 37.7) years who worked at least 8 h a day for more than 3 weeks were compared with those of 50 healthy surgeons in sim...

journal_title：European urology

authors： Gumus E,Miroglu C,Horasanli K,Ekinci M,Saporta L,Kilinc F

更新日期：1999-11-01 00:00:00

abstract：:Preliminary investigation of cell-mediated immunity (CMI) in 49 patients harboring renal cell carcinoma (RCC) by the migration inhibition factor (MIF) tests as compared to 47 patients with simple renal cysts or normal kidneys established the specificity (85%) and reproducibility of this test. A retrospective analysis ...

journal_title：European urology

authors： Gillon G,Livni E,Servadio C

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVES:To evaluate the long-term results of the transvaginal needle suspension operation for urinary stress incontinence. MATERIALS AND METHODS:A total of 88 women with proved genuine stress incontinence were treated with transvaginal needle suspension with fixation of suspension sutures to the rectus fascia using...

journal_title：European urology

authors： Gilja I

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Patients with end-stage renal disease (ESRD) are at risk of developing renal tumours. OBJECTIVE:Compare clinical, pathologic, and outcome features of renal cell carcinomas (RCCs) in ESRD patients and in patients from the general population. DESIGN, SETTING, AND PARTICIPANTS:Twenty-four French university de...

journal_title：European urology

authors： Neuzillet Y,Tillou X,Mathieu R,Long JA,Gigante M,Paparel P,Poissonnier L,Baumert H,Escudier B,Lang H,Rioux-Leclercq N,Bigot P,Bernhard JC,Albiges L,Bastien L,Petit J,Saint F,Bruyere F,Boutin JM,Brichart N,Karam G

更新日期：2011-08-01 00:00:00

abstract：:Prostatic abscess is a rare but severe disease. Conventional therapy is transurethral resection of the prostatic abscess. Since the advent of transrectal ultrasound (TRUS) a minimal-invasive treatment of prostatic abscess by TRUS-guided perineal drainage under local anesthesia is available. We report on our experience...

journal_title：European urology

authors： Bachor R,Gottfried HW,Hautmann R

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Recent large high-quality trials have questioned the clinical effectiveness of medical expulsive therapy using tamsulosin for ureteral stones. OBJECTIVE:To evaluate the efficacy and safety of tamsulosin for distal ureteral stones compared with placebo. DESIGN, SETTING, AND PARTICIPANTS:We conducted a doubl...

journal_title：European urology

authors： Ye Z,Zeng G,Yang H,Tang K,Zhang X,Li H,Li W,Wu Z,Chen L,Chen X,Liu X,Deng Y,Pan T,Xing J,Wang S,Cheng Y,Gu X,Gao W,Yang J,Zhang Y,Mi Q,Qi L,Li J,Hu W,Liang P,Sun Z,Xu C,Long Y,Liao Y,Liu S,Liu

更新日期：2018-03-01 00:00:00

abstract：:The first 400 patients treated on an inpatient basis at our center underwent bacteriological follow-up after extracorporeal lithotripsy (ECL) for ureteric or renal stones. 278 patients did not have any urinary tract infection on the urine culture before ECL. They did not receive any antibiotic prophylaxis and 4.8% of ...

journal_title：European urology

authors： Charton M,Vallancien G,Veillon B,Prapotnich D,Mombet A,Brisset JM

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Robot-assisted thrombectomy (RAT) for inferior vena cava (IVC) thrombus (RAT-IVCT) is being increasingly reported. However, the techniques and indications for robot-assisted cavectomy (RAC) for IVC thrombus are not well described. OBJECTIVE:To develop a decision-making program and analyze multi-institutiona...

journal_title：European urology

authors： Shi T,Huang Q,Liu K,Du S,Fan Y,Yang L,Peng C,Shen D,Wang Z,Gao Y,Gu L,Niu S,Ai Q,Li H,Liu F,Li Q,Wang H,Guo A,Fu B,Yang X,Zhang X,Wang D,Wang D,Guo H,Li H,Olivero A,Fam XI,Ma X,Wang B,Zhang X

更新日期：2020-10-01 00:00:00

abstract：:The descriptive epidemiology of testicular cancer in Denmark shows that the incidence of both seminoma and non-seminoma has increased gradually since the 1940s to the present. The age-incidence pattern has remained unchanged, and is the same in the Nordic countries despite variation in the overall incidence level. Men...

journal_title：European urology

authors： Møller H

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to determine the prognostic power of Ki-67 immunostaining in renal cell carcinomas (RCC). METHODS:Clinical follow-up data were reviewed in 111 RCC and the results of Ki-67 immunolabelling were correlated to standard prognostic factors and survival data of the patients. RESULTS:Ki-67...

journal_title：European urology

authors： Aaltomaa S,Lipponen P,Ala-Opas M,Eskelinen M,Syrjänen K

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to compare the effects of the nonsteroidal antiandrogen flutamide plus the LH-RH analogue goserelin acetate (combined androgen blockade [CAB]) with goserelin acetate alone in patients with advanced prostate cancer. The original analyses at 25 and 56 months of follow-up have been repo...

journal_title：European urology

authors： Tyrrell CJ,Altwein JE,Klippel F,Jurincic-Winkler C,Varenhorst E,Lunglmayr G,Boccardo F,Holdaway IM,Haefliger JM,Jordaan JP

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Radical perineal prostatectomy (RPP) has been revived with the advent of single-port (SP) robotic surgery. However, its interest and precise role need to be evaluated and better defined. OBJECTIVE:To describe in detail the technique of SP-RPP and compare initial perioperative outcomes with those of multipor...

journal_title：European urology

authors： Lenfant L,Garisto J,Sawczyn G,Wilson CA,Aminsharifi A,Kim S,Schwen Z,Bertolo R,Kaouk J

更新日期：2020-12-20 00:00:00

abstract：OBJECTIVE:Congenital bladder diverticula (CBD) usually occur in areas where the muscle is inadequately formed, typically at the ureterovesical junction, or between bundles of hypertrophied muscle. CBD are mostly asymptomatic and the cases are found incidentally. Occasionally, some cases of CBD may produce urinary obstr...

journal_title：European urology

authors： Sarihan H,Abes M

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVES:To study active surveillance as a management option for the important number of prostate cancer patients who would not have been diagnosed in the absence of screening. PATIENTS AND METHODS:We analyzed baseline characteristics and outcome parameters of all men on active surveillance who were screen-detected ...

journal_title：European urology

authors： Roemeling S,Roobol MJ,de Vries SH,Wolters T,Gosselaar C,van Leenders GJ,Schröder FH

更新日期：2007-05-01 00:00:00

abstract：:10 patients underwent transurethral thermotherapy and after few days were submitted to open prostatectomy. The surgical specimens were compared to those of 2 other patients used as controls. Pathological specimens were evaluated using histological and immunohistochemical stains. Microscopic examination showed a well-p...

journal_title：European urology

authors： Perachino M,Bozzo W,Puppo P,Vitali A,Ardoino S,Ferro MA

更新日期：1993-01-01 00:00:00