Practical aspects of metastatic castration-resistant prostate cancer management: patient case studies.

abstract：OBJECTIVE:To present the results of endopyelotomy using endoluminal ultrasonography (EUS) to identify crossing vessels, as the success rates of endopyelotomy are generally lower than pyeloplasty, especially in patients with crossing vessels. PATIENTS AND METHODS:Forty-one consecutive patients who underwent EUS before ...

journal_title：BJU international

authors： Parkin J,Evans S,Kumar PV,Timoney AG,Keeley FX Jr

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:To determine the value of measuring serum concentrations of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) in patients with benign prostatic hyperplasia (BPH), advanced and localized prostate cancer, and thus assess the role of angiogenesis factors as markers of malignancy...

journal_title：BJU international

authors： Walsh K,Sherwood RA,Dew TK,Mulvin D

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:To prospectively investigate the presentation of germ cell tumours (GCTs) of the testis in terms of stage or histology, as the incidence of this disease in increasing. PATIENTS AND METHODS:Patients diagnosed with GCT of the testis between 1983 and 2002 were categorised into three periods depending on the dat...

journal_title：BJU international

authors： Powles TB,Bhardwa J,Shamash J,Mandalia S,Oliver T

更新日期：2005-06-01 00:00:00

abstract：:What is known on the subject? and What does the study add? Substantial experience of the outcomes has been gathered regarding the acute and sub-acute experience with various types of corrective procedures for POP. These include long-term POP correction as well as more recent recognition of improvement in functional di...

journal_title：BJU international

authors： Gomelsky A,Penson DF,Dmochowski RR

更新日期：2011-06-01 00:00:00

abstract：UNLABELLED:What's known on the subject? and what does the study add?: Variations in the type of urinary diversion exist for patients undergoing radical cystectomy. Although its use has been increasing from 2001 to 2008, patients who are older, female, and primary insured by Medicaid are less likely to receive continent...

journal_title：BJU international

authors： Kim SP,Shah ND,Weight CJ,Thompson RH,Wang JK,Karnes RJ,Han LC,Ziegenfuss JY,Frank I,Tollefson MK,Boorjian SA

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:To illustrate the ultrastructural fibre composition of the rat cavernosal nerve at serial levels, from its origin in the main pelvic ganglion to its termination in the corpus cavernosum of the distal penile shaft, and to develop a technique that permits repeated electrophysiological recording from the fibres ...

journal_title：BJU international

authors： Schaumburg HH,Zotova E,Cannella B,Raine CS,Arezzo J,Tar M,Melman A

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the comparative effectiveness of electromyographic (EMG) biofeedback with verbal instructions as learning tools of pelvic muscle exercises (PMEs) in the early management of urinary incontinence after radical prostatectomy. PATIENTS AND METHODS:Forty-two consecutive patients (mean age 64 years, sd...

journal_title：BJU international

authors： Floratos DL,Sonke GS,Rapidou CA,Alivizatos GJ,Deliveliotis C,Constantinides CA,Theodorou C

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVE:To develop and validate an in vitro method suitable for the quantitative investigation of the growth of calcium oxalate stones through to a clinically significant size. MATERIALS AND METHODS:Small fragments of calcium oxalate calculi were suspended in a mixed suspension/mixed product removal crystalliser sup...

journal_title：BJU international

authors： Ananth K,Kavanagh JP,Walton RC,Rao PN

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVES:To investigate the long-term outcomes of laparoscopic radical prostatectomy (LRP). PATIENTS AND METHODS:In all, 1138 patients underwent LRP during a 163-month period from 2000 to 2008, of which 51.5%, 30.3% and 18.2% were categorised into D'Amico risk groups of low-, intermediate- and high-risk, respectivel...

journal_title：BJU international

authors： Soares R,Di Benedetto A,Dovey Z,Bott S,McGregor RG,Eden CG

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:To evaluate changes in bone mass and fracture risk in patients with prostate cancer on androgen-deprivation therapy (ADT) and with a basal T-score of >-2.0, who were treated with an oral bisphosphonate, as such patients treated with ADT are at increased risk of bone loss and bone fracture. PATIENTS AND METHO...

journal_title：BJU international

authors： Planas J,Trilla E,Raventós C,Cecchini L,Orsola A,Salvador C,Placer J,Encabo G,Morote J

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVES:To investigate whether micronutrients in support of the one-carbon cycle and glutathione synthesis are effective in improving sperm damage after surgical varicocoele induction in rats and whether any effect is achieved without a rebound reductive stress as seen with oral antioxidants. MATERIALS AND METHODS:...

journal_title：BJU international

authors： Mohammadi P,Hassani-Bafrani H,Tavalaee M,Dattilo M,Nasr-Esfahani MH

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVES:To evaluate partial nephrectomy (PN) use in patients at higher risk for clinical progression, using a large national database of American patients. PATIENTS AND METHODS:We performed a retrospective review of patients with cN0/cM0 renal cell carcinoma from 2003 to 2011 using the National Cancer Data Base. Ou...

journal_title：BJU international

authors： Maurice MJ,Zhu H,Kim SP,Abouassaly R

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy, tolerability and safety of darifenacin, a muscarinic M3 selective receptor antagonist (M3 SRA), from an analysis of pooled data from three phase III, multicentre, double-blind clinical trials in patients with overactive bladder (OAB). PATIENTS AND METHODS:After a 4-week washout/run-...

journal_title：BJU international

authors： Chapple C,Steers W,Norton P,Millard R,Kralidis G,Glavind K,Abrams P

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVE:To characterize the clinical outcomes of androgen deprivation therapy (ADT) as the sole therapy for localized prostate cancer, and to determine independent predictors of disease progression, as recent studies indicate an increasing use of ADT. PATIENTS AND METHODS:The records of all patients with cT1-4NXM0 a...

journal_title：BJU international

authors： Janoff DM,Peterson C,Mongoue-Tchokote S,Peters L,Beer TM,Wersinger EM,Mori M,Garzotto M

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:To study the role of peroperative transrectal ultrasonography (peTRUS) for the dissection of the bladder neck during robot-assisted laparoscopic prostatectomy (RALP). PATIENTS AND METHODS:Integrated peTRUS in the da Vinci S system (Intuitive Surgical, Sunnyvale, CA, USA) was used for bladder neck identificat...

journal_title：BJU international

authors： van der Poel HG,de Blok W,Bex A,Meinhardt W,Horenblas S

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:To assess the relationship between the histological features of renal chromophobe cell carcinoma (CCC) and clinical outcome in patients with renal cell carcinoma. PATIENTS AND METHODS:From 1957 to 1996, 41 patients with CCC of the kidney (4.9% of all kidney carcinomas) were treated at our university hospital...

journal_title：BJU international

authors： Onishi T,Oishi Y,Yanada S,Abe K,Hasegawa T,Maeda S

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE:To identify predictors of delayed therapy with curative intent, an increasingly common option in contemporary patients with prostate cancer who initially choose watchful waiting. PATIENTS AND METHODS:The characteristics of all patients at one institution and diagnosed with T1-4NXM0 prostate cancer between 19...

journal_title：BJU international

authors： el-Geneidy M,Garzotto M,Panagiotou I,Hsieh YC,Mori M,Peters L,Klein T,Beer TM

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVE:To test the replicability and robustness of findings about urological symptoms in men and women, classified using an objective statistical method, cluster analysis, by planned sensitivity analyses conducted within and across two large, epidemiological studies of lower urinary tract symptoms. METHODS:Sensitiv...

journal_title：BJU international

authors： Rosen RC,Coyne KS,Henry D,Link CL,Cinar A,Aiyer LP,Mollon P,Kaplan SA,Roehrborn CG,Thompson C

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:To determine the effect of a deep and narrow pelvis on apical positive surgical margins (PSM) at radical prostatectomy (RP), controlling for other clinical and pathological variables and surgical approach, i.e. open retropubic (RRP) vs laparoscopic (LRP), as apical dissection is expected to be more challengin...

journal_title：BJU international

authors： Matikainen MP,von Bodman CJ,Secin FP,Yunis LH,Vora K,Guillonneau B,Laudone V,Eastham JA,Scardino PT,Akin O,Rabbani F

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:We evaluated survival outcomes of partial nephrectomy (PN) and radical nephrectomy (RN) for clinical T2 renal masses (cT2RM) controlling for R.E.N.A.L. nephrometry score. PATIENTS AND METHODS:A two-centre study comprised of 202 patients with cT2RM who underwent RN (122) or PN (80) between July 2002 and June ...

journal_title：BJU international

authors： Kopp RP,Mehrazin R,Palazzi KL,Liss MA,Jabaji R,Mirheydar HS,Lee HJ,Patel N,Elkhoury F,Patterson AL,Derweesh IH

更新日期：2014-11-01 00:00:00

abstract：:To assess the evidence for the concept that the androgen receptor of prostate cancer (PCa) cells becomes saturated when testosterone values exceed castrate levels, so that testosterone administration in hypogonadal men with untreated PCa does not stimulate tumour growth. To propose basic criteria for administration of...

journal_title：BJU international

authors： Morales A

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVES:To evaluate the proportion of patients achieving clinically meaningful improvement of lower urinary tract symptoms suggestive of benign prostatic hyperplasia (BPH-LUTS) with tadalafil using two definitions of response. PATIENTS AND METHODS:Post hoc integrated analysis of four placebo-controlled studies in m...

journal_title：BJU international

authors： Nickel JC,Brock GB,Herschorn S,Dickson R,Henneges C,Viktrup L

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the prevalence of depression, anxiety and distress among active surveillance (AS) and radical prostatectomy (RP) patients. To evaluate the impact of these symptoms at baseline on urinary and sexual quality of life at follow-up. PATIENTS AND METHODS:Patients managed with AS or RP who completed val...

journal_title：BJU international

authors： Punnen S,Cowan JE,Dunn LB,Shumay DM,Carroll PR,Cooperberg MR

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:To examine whether a history of sexually transmitted infections (STIs) or positive STI serology is associated with prevalent and incident benign prostatic hyperplasia (BPH)/lower urinary tract symptoms (LUTS)-related outcomes in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. METHODS:Self-...

journal_title：BJU international

authors： Breyer BN,Huang WY,Rabkin CS,Alderete JF,Pakpahan R,Beason TS,Kenfield SA,Mabie J,Ragard L,Wolin KY,Grubb RL 3rd,Andriole GL,Sutcliffe S

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To evaluate contrast-enhanced ultrasonography (US) using cadence-contrast pulse sequencing (CPS) technology, compared with systematic biopsy for detecting prostate cancer, as grey-scale US has low sensitivity and specificity for detecting prostate cancer. PATIENTS AND METHODS:In all, 44 men with suspicious p...

journal_title：BJU international

authors： Aigner F,Pallwein L,Mitterberger M,Pinggera GM,Mikuz G,Horninger W,Frauscher F

更新日期：2009-02-01 00:00:00

abstract：UNLABELLED:What's known on the subject? and What does the study add? To date, there has been limited impetus to examine the use of cytarabine in prostate cancer. We presented preliminary laboratory data to suggest its utility in the castration refractory prostate cancer (CRPC) population which, combined with a previous...

journal_title：BJU international

authors： Dhani NC,Emmenegger U,Adams L,Jongstra J,Tannock IF,Sridhar SS,Knox JJ,Day JR,Groskopf J,Joshua AM

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVES:To determine the risk of failure during drug development in castration-resistant prostate cancer (CRPC) and to identify factors that could improve outcomes. METHODS:We investigated CRPC by analysing compounds in phase I to phase III clinical trials between 1998 and April 2011. Drug development failures were...

journal_title：BJU international

authors： Tenuta A,Klotz L,Parker JL

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the variability of subjective tutor performance improvement (Pi) assessment and to compare it with a novel measurement algorithm: the Pi score. MATERIALS AND METHODS:The Pi-score algorithm considers time measurement and number of errors from two different repetitions (first and fifth) of the same...

journal_title：BJU international

authors： Veneziano D,Canova A,Arnolds M,Beatty JD,Biyani CS,Dehò F,Fiori C,Hellawell GO,Langenhuijsen JF,Pini G,Rodriguez Faba O,Siena G,Skolarikos A,Tokas T,Van Cleynenbreugel BSEP,Wagner C,Tripepi G,Somani B,Lima B

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the experience and views regarding live surgical broadcasts (LSB) among European urologists attending the European Association of Urology Robotic Urology Society (ERUS) congress in September 2012. MATERIALS AND METHODS:An anonymous survey was distributed via email inviting the participants of the...

journal_title：BJU international

authors： Khan SA,Chang RT,Ahmed K,Knoll T,van Velthoven R,Challacombe B,Dasgupta P,Rane A

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:To review time-trends in the use of perioperative chemotherapy and its impact on oncological outcomes in patients with bladder urothelial cancer (UC) at a single tertiary institution. PATIENTS AND METHODS:Using electronic and paper medical records, 89 patients were identified who underwent radical cystectomy...

journal_title：BJU international

authors： Liew MS,Azad A,Tafreshi A,Eapen R,Bolton D,Davis ID,Sengupta S

更新日期：2013-11-01 00:00:00