Abstract：
UNLABELLED:Sleep duration has been identified as risk factor for obesity already in children. Besides investigating the role of fat mass (FM), this study addressed the question whether endocrine mechanisms act as intermediates in the association between sleep duration and overweight/obesity. Within the framework of the IDEFICS study, the present research was conducted in 609 German resident children aged 2-9 years with information on fasting insulin, C-reactive protein and cortisol levels next to anthropometric measurements and parental questionnaires. Emphasising methodological aspects, an age-specific measure of sleep duration was derived to account for alteration in sleep duration during childhood/period of growth. Multivariate linear regression and quantile regression models confirmed an inverse relationship between sleep duration and measures of overweight/obesity. The estimate for the association of sleep duration and body mass index (BMI) was approximately halved after adjustment for FM, but remained significant. The strength of this association was also markedly attenuated when adjusting for insulin mainly for the upper BMI quantiles (Q80, β = -0.36 vs. β = -0.26; Q95, β = -0.87 vs. β = -0.47). Adjustment for cortisol and CrP did not yield this attenuation. CONCLUSION:The inverse relationship between sleep duration and BMI is mainly explained by the association between sleep duration and FM. Insulin may explain part of this association, in particular at the upper tail of the BMI distribution.
journal_name
Eur J Pediatrjournal_title
European journal of pediatricsauthors
Börnhorst C,Hense S,Ahrens W,Hebestreit A,Reisch L,Barba G,von Kries R,Bayer O,IDEFICS Consortium.doi
10.1007/s00431-011-1670-8subject
Has Abstractpub_date
2012-07-01 00:00:00pages
1029-38issue
7eissn
0340-6199issn
1432-1076journal_volume
171pub_type
杂志文章,多中心研究abstract：:The performance of two triggering systems was compared during patient triggered ventilation (PTV) of infants ventilator-dependent beyond 10 days of age. Ten infants were studied who had a median gestational age of 26.5 weeks and a postnatal age of 15.5 days. PTV was administered via the SLE ventilator and the two trig...
journal_title：European journal of pediatrics
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF01957937
更新日期：1992-11-01 00:00:00
abstract：:The Rubinstein-Taybi syndrome is a condition characterized by mental retardation, typical facial changes and broad thumbs and big toes. The cause is unknown; almost all cases are sporadic. We describe a mother and son with Rubinstein-Taybi syndrome. Literature search documented at least 413 cases with 558 sibs. An aff...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00595907
更新日期：1989-02-01 00:00:00
abstract：UNLABELLED:Growth hormone (GH) secretion was determined by evaluating circadian GH profiles for 24 h and GH responses to clonidine stimulation test and insulin-stimulated hypoglycaemia (ITT), in nine prepubertal children with beta-thalassaemia major (TM) and 17 with non-GH deficient short stature (NGHDSS). The TM child...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02029352
更新日期：1995-06-01 00:00:00
abstract：:Cardiovascular abnormalities were evaluated in 64 children aged between 1 year 9 months and 25 years with mucopolysaccharidoses (MPS) and related disorders. A heart murmur was heard in 18 patients, but in only 6 was it characteristic for specific valvular lesions. Echocardiography was performed in 63 children. In one ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310050872
更新日期：1998-07-01 00:00:00
abstract：:Despite advancement in medical care, Rh alloimmunisation remains a major cause of neonatal hyperbilirubinaemia, neuro-morbidity, and late-onset anaemia. Delayed cord clamping (DCC), a standard care now-a-days, is yet not performed in Rh-alloimmunised infants due to paucity of evidence. Hence, we randomised these infan...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-020-03578-8
更新日期：2020-06-01 00:00:00
abstract：OBJECTIVES:The aim of the 'Motorik-Modul' (MoMo Basiserhebung, www.motorik-modul.de ) was to establish prevalence measurements on physical fitness and physical activity in German children and adolescents and to identify differences between age groups and genders. A total of 4,529 children and adolescents between the ag...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-010-1391-4
更新日期：2011-09-01 00:00:00
abstract：:Central line-associated bloodstream infection (CLABSI) is a significant cause of morbidity and mortality in neonatal intensive care units (NICUs). A "bundle" is defined as a combination of evidence-based interventions that provided they are followed collectively and reliably, are proven to improve patient outcomes. Th...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-020-03844-9
更新日期：2021-02-01 00:00:00
abstract：UNLABELLED:Periventricular leucomalacia is a condition that causes lifelong disability and considerable economic burden. It occurs in premature infants of less than 32 weeks gestation due to their unique anatomical features. The white matter of these infants is poorly vascularised and contains oligodendrocyte progenito...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s00431-004-1477-y
更新日期：2004-08-01 00:00:00
abstract：UNLABELLED:Our aim was to determine whether the chest radiograph appearance at 7 days predicted chronic lung disease development (oxygen dependency at 36 weeks post-menstrual age) or death before discharge and if it was a better predictor than readily available clinical data. Two consecutive studies were performed. In ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-003-1332-6
更新日期：2004-01-01 00:00:00
abstract：UNLABELLED:The pathogenesis of sporadic hemiplegic migraine remains unclear, and perfusion-weighted magnetic resonance imaging (PWI) has been used for characterization of hemodynamic changes in migraine aura. We report a case of sporadic hemiplegic migraine in which magnetic resonance perfusion imaging showed left cere...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-015-2609-2
更新日期：2016-02-01 00:00:00
abstract：:A term newborn infant developed a right sciatic nerve palsy after ischaemic necrosis of the gluteal region following umbilical arterial catheterization. The nerve lesion was believed to be caused by entrapment and compression by scar tissue. Recovery was slow and remained incomplete up to 6 months of age. ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00439407
更新日期：1986-09-01 00:00:00
abstract：:Strategies for the treatment of cystathionine beta-synthase (CBS) deficiency include (1) increasing residual enzyme activity by giving pyridoxine in those patients with vitamin responsive variants, (2) reducing the load on the affected pathway with a low methionine diet and supplementing the diet with cysteine; and (3...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/pl00014308
更新日期：1998-04-01 00:00:00
abstract：:Scimitar syndrome is a rare congenital cardiopulmonary malformation characterized by hypoplasia of the right lung and drainage of the right pulmonary veins into the vena cava inferior. It may also be associated with cardiac dextroversion and anomalies of the tracheobronchial system, cardiovascular system, and diaphrag...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-010-1153-3
更新日期：2010-10-01 00:00:00
abstract：:A large number of ventilation strategies are now available for the neonate. This review has focused on new information, that is, studies published since 2000 and the implication of their results for current clinical practice. Meta-analysis of randomised trials has demonstrated that assist control and synchronous inter...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s00431-007-0513-0
更新日期：2007-10-01 00:00:00
abstract：:Specialist paediatric services manage a variety of presentations of functional somatic symptoms. We aimed to describe the presentation and management of children and adolescents with somatic symptom and related disorders (SSRDs) requiring admission to a tertiary children's hospital with the objective of informing the ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-020-03867-2
更新日期：2020-11-13 00:00:00
abstract：:A girl developed acute agranulocytosis (45/mm3), 37 days after the onset of infectious mononucleosis. The bone marrow showed myeloid hyperplasia with maturation arrest and erythroid hypoplasia. A normal amount of colony forming units of granulocytes and macrophages (CFU-GM) colonies with a relative high number of clus...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF01959523
更新日期：1990-07-01 00:00:00
abstract：:The aim of this retrospective study was to describe the epidemiology and spectrum of infections of admitted pediatric refugees and asylum seekers in a tertiary referral hospital in a high-income country in Europe. We identified recent refugees and asylum seekers < 18 years of age admitted to the University Children's ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-017-3014-9
更新日期：2017-12-01 00:00:00
abstract：UNLABELLED:During puberty fat-free mass (FFM) and fat mass (FM) change quickly and these changes are influenced by sex and obesity. Since it is not completely known how these changes affect resting metabolic rate (RMR), the aim of the present study was to investigate the effect of body composition, age, sex and puberta...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310050618
更新日期：1997-05-01 00:00:00
abstract：UNLABELLED:The objective of this study was to study the experiences of parents of preterm infants who use social networking sites and the potential of such sites for gathering information and facilitating personal exchange. An anonymous self-reporting questionnaire was administered to parents of infants below 1,500 g b...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-013-2067-7
更新日期：2013-12-01 00:00:00
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journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00496426
更新日期：1988-05-01 00:00:00
abstract：:A 4.5-year-old male patient is described with chorioretinopathy, minor facial anomalies, delayed closure of the fontanel, mental retardation, moderate hypotonia, epilepsy and hepatic fibrosis. Postural control, intentional vocalising and manual dexterity were superior to the performance of patients with classical Zell...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00441774
更新日期：1985-11-01 00:00:00
abstract：:Vascularization of the arms has been studied by impedance plethysmography (rheography) in eight children with Poland syndrome, a common malformation characterized by unilateral hand anomaly and ipsilateral aplasia of the inferior head of the pectoralis major muscle. A marked decrease of the velocity of the systolic in...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00496922
更新日期：1978-05-22 00:00:00
abstract：:We compared epinephrine and dopamine as a first-line vasoactive drug in 40 neonates (enrolled in two gestational age strata ≤ 306/7 and ≥ 310/7 weeks) with fluid-refractory septic shock. Epinephrine or dopamine was initiated at 0.2 or 10 μg/kg/min, respectively. If shock persisted after 15 min, epinephrine or dopamine...
journal_title：European journal of pediatrics
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00431-018-3195-x
更新日期：2018-09-01 00:00:00
abstract：:Screening of neonates for inborn errors of metabolism has been carried out on a national level since 1969 in the Federal Republic of Germany. To raise the reliability of these routine investigations, we introduced an external quality control in March 1982. Every 2 months ten filter paper samples were sent to the scree...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00451907
更新日期：1985-07-01 00:00:00
abstract：:Of all newborn infants, 5% require some degree of basic life support at birth. Newborn resuscitation therefore is one of the most frequent procedures carried out in medicine. It is therefore important that the routines in use are evidence based. Newborn resuscitation can be divided into ten steps: (1) initial stabilis...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/pl00014284
更新日期：1998-01-01 00:00:00
abstract：UNLABELLED:To evaluate the indications, underlying cardiac disorders, efficacy and complications involved with implantable cardioverter-defibrillators (ICDs) in paediatric patients in The Netherlands, the records of all patients aged 18 years or younger who underwent ICD placement were reviewed retrospectively. Between...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-005-1668-1
更新日期：2005-07-01 00:00:00
abstract：:Two children with congenital cytomegalovirus infection and intracerebral echogenicities were investigated by computer sonography and colour Doppler imaging (CDI). By simultaneous imaging of brain tissue and CDI, blood flow within the stripe-like echogenicities of the basal ganglia was demonstrated. Using CDI the echog...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF01959476
更新日期：1990-11-01 00:00:00
abstract：:Adolescence obesity and depression are increasingly prevalent and are associated with various health complications. The aim of this study was to examine the association between weight status (normal weight, overweight, and obese) and depressive symptoms in adolescents and to explore the probable mediators, including o...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-012-1753-1
更新日期：2012-08-01 00:00:00
abstract：UNLABELLED:About 50% of intersex cases are due to male pseudohermaphroditism, and of these cases, 50% are not clarified aetiologically. The association of idiopathic male pseudohermaphroditism and prenatal growth retardation has been recently reported. The aim of this study was to verify whether there was a difference ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-005-1626-y
更新日期：2005-05-01 00:00:00
abstract：:A 4-month-old boy was admitted for having diffuse eruption in the perianal region, legs, trunk hands, and face with failure to thrive, edema, hypoalbuminemia, and anemia. The patient was thought to have acrodermatitis enteropathica-like eruption due to malabsorption. The eruption completely resolved with enzyme supple...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-008-0825-8
更新日期：2009-01-01 00:00:00
