Decreased accumulation of ultrasound contrast in the liver of nonalcoholic steatohepatitis rat model.

abstract：:It has been known that peripheral adverse event is caused by peripheral antimuscarinic action, from hyoscine butylbromide (Buscopan; Boehringer Ingelheim, Germany) used as a premedication for endoscopy. However, symptoms or signs associated with the central nervous system are rarely reported in the field of anesthesio...

journal_title：World journal of gastroenterology

authors： Lee H,Son HJ,Rhee PL,Kim JJ,Rhee JC

更新日期：2007-07-28 00:00:00

abstract：AIM:To analyze loss of heterozygosity (LOH) and homozygous deletion on p53 gene (exon2-3, 4 and 11), chromosome 10q22-10q23 and 22q11.2 -22q12.1 in human hepatocellular carcinoma (HCC). METHODS:PCR and PCR-based microsatellite polymorphism analysis techniques were used. RESULTS:LOH was observed at D10S579 (10q22-10q2...

journal_title：World journal of gastroenterology

authors： Zhu GN,Zuo L,Zhou Q,Zhang SM,Zhu HQ,Gui SY,Wang Y

更新日期：2004-07-01 00:00:00

abstract：:In mammals, the intestinal epithelium is a tissue that contains two distinct pools of stem cells: active intestinal stem cells and reserve intestinal stem cells. The former are located in the crypt basement membrane and are responsible for maintaining epithelial homeostasis under intact conditions, whereas the latter ...

journal_title：World journal of gastroenterology

authors： Cui S,Chang PY

更新日期：2016-08-21 00:00:00

abstract：AIM:To identify a small, clinically applicable immunohistochemistry (IHC) panel that could be combined with magnetic resonance imaging (MRI)-detected extramural vascular invasion (EMVI) for assessment of prognosis concerning the non-advanced rectal cancer patients prior to operation. METHODS:About 329 patients with pa...

journal_title：World journal of gastroenterology

authors： Li XF,Jiang Z,Gao Y,Li CX,Shen BZ

更新日期：2016-10-14 00:00:00

abstract：AIM:H101, an E1B 55 kD gene deleted adenovirus, has been shown to possess oncolysis activity experimentally and proved to be safe in preliminary phase I study. The current study was designed to evaluate its anti-tumor activity and toxicity in combination with chemotherapy in patients with late stage cancers. METHODS:H...

journal_title：World journal of gastroenterology

authors： Lu W,Zheng S,Li XF,Huang JJ,Zheng X,Li Z

更新日期：2004-12-15 00:00:00

abstract：:Ghrelin, as a kind of multifunctional protein polypeptide, is mainly produced in the fundus of the stomach and can promote occurrence and development of many tumors, including gastrointestinal tumors, which has been proved by the relevant researches. Most gastrointestinal stromal tumors (GISTs, about 80%), as the most...

journal_title：World journal of gastroenterology

authors： Zhu CZ,Liu D,Kang WM,Yu JC,Ma ZQ,Ye X,Li K

更新日期：2017-03-14 00:00:00

abstract：:Somatostatinomas are extremely rare neuroendocrine tumors of the gastrointestinal tract, first described in the pancreas in 1977 and in the duodenum in 1979. They may be functional and cause somatostatinoma or inhibitory syndrome, but more frequently are non-functioning pancreatic endocrine tumors that produce somatos...

journal_title：World journal of gastroenterology

authors： Colović RB,Matić SV,Micev MT,Grubor NM,Atkinson HD,Latincić SM

更新日期：2009-12-14 00:00:00

abstract：:The discovery of induced pluripotent stem cells (iPSCs) unraveled a mystery in stem cell research, after identification of four re-programming factors for generating pluripotent stem cells without the need of embryos. This breakthrough in generating iPSCs from somatic cells has overcome the ethical issues and immune r...

journal_title：World journal of gastroenterology

authors： Subba Rao M,Sasikala M,Nageshwar Reddy D

更新日期：2013-06-14 00:00:00

abstract：:Cholangiocarcinoma (CC) is rare malignant tumors composed of cells that resemble those of the biliary tract. It is notoriously difficult to diagnose, and is associated with a high mortality. Traditionally, CC is divided into intrahepatic and extrahepatic disease according to its location within the biliary tree. Intra...

journal_title：World journal of gastroenterology

authors： Shimoda M,Kubota K

更新日期：2007-03-14 00:00:00

abstract：BACKGROUND:Conventionally, the low luminous intensity, low image resolution, and difficulty in operation have been reported with the ultrathin endoscope. However, it has markedly advanced recently. The improvement of the diagnostic ability is expected. AIM:To compare the early gastric cancer diagnostic ability of an u...

journal_title：World journal of gastroenterology

authors： Suzuki T,Kitagawa Y,Nankinzan R,Yamaguchi T

更新日期：2019-03-21 00:00:00

abstract：:Transforming growth factor-beta (TGF-beta), a prototype of multifunctional cytokine, is a key regulator of extracellular matrix (ECM) assembly and remodeling. Specifically, TGF-beta isoforms have the ability to induce the expression of ECM proteins in mesenchymal cells, and to stimulate the production of protease inhi...

journal_title：World journal of gastroenterology

authors： Verrecchia F,Mauviel A

更新日期：2007-06-14 00:00:00

abstract：AIM:To investigate the effects of short-term application of low-dose growth hormone on trace element metabolism and blood glucose in surgical patients. METHODS:A total of 48 consecutive patients undergoing abdominal operations were randomized to receive either subcutaneous rhGH (0.15 IU/kg) or placebo (menstruum) inje...

journal_title：World journal of gastroenterology

authors： Qian K,Wan Z,Hao LS,Zhang MM,Zhou Y,Wu XT

更新日期：2007-12-14 00:00:00

abstract：AIM:To define the common deleted region on the long arm of haman chromosome 7q linked to primary gastric carcinomas in Chinese by loss of heterozygosity (LOH) and its clinical significance. METHODS:Nine microsatellite markers distributed over chromosome 7q with an average marker density of 10cM were used to examine 70...

journal_title：World journal of gastroenterology

authors： Weng DS,Li JT,Mai SJ,Pan ZZ,Feng BJ,Feng QS,Huang LX,Wang QJ,Li YQ,Yu XJ,Chen SP,He J,Xia JC

更新日期：2006-04-21 00:00:00

abstract：AIM:To investigate the prevalence and characteristics of uninvestigated dyspepsia among college students in Zhejiang Province. METHODS:Young adult students attending undergraduate (within the 4-year program) and graduate (only first-year students) colleges in Zhejiang Province were recruited between November 2010 and ...

journal_title：World journal of gastroenterology

authors： Li M,Lu B,Chu L,Zhou H,Chen MY

更新日期：2014-04-07 00:00:00

abstract：AIM:To compare the outcome of upper gastrointestinal bleeding (UGIB) between patients receiving restrictive and liberal transfusion. METHODS:PubMed, EMBASE, and Cochrane Library databases were employed to identify all relevant randomized controlled trials regarding the outcome of UGIB after restrictive or liberal tran...

journal_title：World journal of gastroenterology

authors： Wang J,Bao YX,Bai M,Zhang YG,Xu WD,Qi XS

更新日期：2013-10-28 00:00:00

abstract：:Alcohol-related cirrhosis is a consequence of heavy and prolonged drinking. Similarly to patients with cirrhosis of other etiologies, patients with alcoholic cirrhosis develop portal hypertension and the hepatic, splanchnic and systemic hemodynamic alterations that follow. However, in alcoholic cirrhosis, some specifi...

journal_title：World journal of gastroenterology

authors： Bolognesi M,Verardo A,Di Pascoli M

更新日期：2014-07-07 00:00:00

abstract：AIM:To study the inhibitory effects of a Shuangling Fuzheng anticancer preparation (SFAP) on the human gastric cancer cell line SGC-7901 in vitro as well as its immune-modulated effects in a cyclophosphamide-treated murine model. METHODS:MTT experiments and immunocytochemistry ABC experiments were performed for detect...

journal_title：World journal of gastroenterology

authors： Chen HS,Chen J,Cui DL,Zheng YY,Xu AH,Chen G,Jia LC

更新日期：2007-12-28 00:00:00

abstract：AIM:To assess long-term effects of Helicobacter pylori (H pylori) eradication on antral G cell morphology and function in patients with and without duodenal ulcer (DU). METHODS:Consecutive dyspeptic patients referred to the endoscopy entered the study. Out of 39 H pylori positive patients, 8 had DU (H pylori +DU) and ...

journal_title：World journal of gastroenterology

authors： Sokic-Milutinovic A,Todorovic V,Milosavljevic T,Micev M,Drndarevic N,Mitrovic O

更新日期：2005-07-21 00:00:00

abstract：AIM:To investigate the relationship between glucose metabolism and glypican-3 (GPC3) expression in hepatocellular carcinoma (HCC). METHODS:Immunohistochemical staining of pathological samples for GPC3 and glucose transporter 1 (GLUT1), and whole-body 18F-FDG PET/CT for measuring tumour glucose uptake were performed in...

journal_title：World journal of gastroenterology

authors： Li YC,Yang CS,Zhou WL,Li HS,Han YJ,Wang QS,Wu HB

更新日期：2018-01-28 00:00:00

abstract：AIM:To test whether ethanol feeding could induce Toll-like receptor 4 (TLR4) responses, assess the hepatoprotective effect of betaine and its inhibitive effect on TLR4 in animal models of alcoholic liver injury. METHODS:Forty-eight female Sprague-Dawley rats were randomly divided into four groups as control, model, lo...

journal_title：World journal of gastroenterology

authors： Shi QZ,Wang LW,Zhang W,Gong ZJ

更新日期：2010-02-21 00:00:00

abstract：AIM:To investigate the reactivity of a panel of 8 mouse anti-hepatitis B surface antigen (HBsAg) monoclonal antibodies (mAbs) using a collection of 9 recombinant HBsAg mutants with a variety of amino acid substitutions mostly located within the "a" region. METHODS:The entire HBs genes previously cloned into a mammalia...

journal_title：World journal of gastroenterology

authors： Roohi A,Yazdani Y,Khoshnoodi J,Jazayeri SM,Carman WF,Chamankhah M,Rashedan M,Shokri F

更新日期：2006-09-07 00:00:00

abstract：BACKGROUND:Incidence and severity variations of inflammatory bowel disease (IBD) have been reported from Western populations between continents and regions of the same countries. However, no data were available from other countries. AIM:To investigate the regional differences in the IBD profiles of pediatric patients ...

journal_title：World journal of gastroenterology

authors： El Mouzan MI,AlEdreesi MH,Hasosah MY,Al-Hussaini AA,Al Sarkhy AA,Assiri AA

更新日期：2020-01-28 00:00:00

abstract：:Alcohol consumption and hepatitis C virus (HCV) infection have a synergic hepatotoxic effect, and the coexistence of these factors increases the risk of advanced liver disease. The main mechanisms of this effect are increased viral replication and altered immune response, although genetic predisposition may also play ...

journal_title：World journal of gastroenterology

authors： Novo-Veleiro I,Alvela-Suárez L,Chamorro AJ,González-Sarmiento R,Laso FJ,Marcos M

更新日期：2016-01-28 00:00:00

abstract：AIM:To study the hemodynamics in the immediate post transplant period and compare patients with alcoholic vs viral cirrhosis. METHODS:Between 2000-2003, 38 patients were transplanted for alcoholic cirrhosis and 28 for postviral cirrhosis. Heart rate (HR), central venous pressure (CVP), mean arterial pressure (MAP), pu...

journal_title：World journal of gastroenterology

authors： Al-Hamoudi WK,Alqahtani S,Tandon P,Ma M,Lee SS

更新日期：2010-02-07 00:00:00

abstract：:The biology of colorectal cancer differs according to its location within the large intestine. A report published in a previous issue of World Journal of Gastroenterology (November 2010) evaluated the importance of tumor location as a risk factor for lymph node metastasis in colorectal cancer, and showed that rectal c...

journal_title：World journal of gastroenterology

authors： Akiyoshi T,Watanabe T,Ueno M,Muto T

更新日期：2011-08-07 00:00:00

abstract：AIM:To assess the efficacy and safety of fourth-generation quinolones for Helicobacter pylori (H. pylori) eradication, we conducted this systematic review and meta-analysis of randomized clinical trials. METHODS:Major literature databases (PubMed, EMBASE and the Cochrane Central Register of Controlled Trials) were sea...

journal_title：World journal of gastroenterology

authors： An Y,Wang Y,Wu S,Wang YH,Qian X,Li Z,Fu YJ,Xie Y

更新日期：2018-08-07 00:00:00

abstract：:Hepatocellular carcinoma (HCC) remains to be one of the top causing cancer-related deaths today. The majority of HCC cases are reported to be the result of chronic hepatitis B virus (HBV) infection. Current treatments for HBV-related HCC revolve around the use of drugs to inhibit viral replication, as a high level of ...

journal_title：World journal of gastroenterology

authors： Tan YL,Chen WN

更新日期：2014-05-28 00:00:00

abstract：AIM:To study the practical use of the model for end-stage liver disease (MELD) on clinic and assess its validity by the concordance (C)-statistic in predicting the prognosis of the patient with severe viral hepatitis. METHODS:One hundred and twenty-one patients were divided into plasma exchange group and non-plasma ex...

journal_title：World journal of gastroenterology

authors： Weng ZH,Cai SQ

更新日期：2005-02-14 00:00:00

abstract：:Human intestinal microbiota create a complex polymicrobial ecology. This is characterised by its high population density, wide diversity and complexity of interaction. Any dysbalance of this complex intestinal microbiome, both qualitative and quantitative, might have serious health consequence for a macro-organism, in...

journal_title：World journal of gastroenterology

authors： Bures J,Cyrany J,Kohoutova D,Förstl M,Rejchrt S,Kvetina J,Vorisek V,Kopacova M

更新日期：2010-06-28 00:00:00

abstract：AIM:To investigate the gastric emptying after bowel preparation to allow general anaesthesia. METHODS:A prospective, non-comparative, and non-randomized trial was performed and registered on Eudra CT database (2011-002953-80) and on www.trial.gov (NCT01398098). All patients had a validated indication for colonoscopy a...

journal_title：World journal of gastroenterology

authors： Coriat R,Polin V,Oudjit A,Henri F,Dhooge M,Leblanc S,Delchambre C,Esch A,Tabouret T,Barret M,Prat F,Chaussade S

更新日期：2014-10-07 00:00:00