Abstract：
:From ancient time leprosy has been regarded as a terrifying, stigmatized disease; nevertheless, its cause remained unidentified up to the late 19th century. For centuries numerous leprosy victims worldwide suffered from its morbidity and were socially isolated. The afflicted individuals were segregated because they were considered 'unclean' and had to live in leper colonies, generally under very poor conditions. Physicians believed that leprosy was an incurable, highly contagious, and hereditary disease. In 1873 the Norwegian physician, Gerhard Armauer Hansen (1841-1912), ended the myth of leprosy and discovered its causative agent, known as Mycobacterium leprae. Hansen's discovery was a great triumph in the fight against leprosy. In the 1930's, the first effective antileprosy drug, dapsone, was introduced and in the early 1980's multi-drug therapy was popularized because of high efficacy in resistant cases. Here, we have presented a brief look at the history of leprosy in the world with special focus on the historical account of leprosy in Iran, particularly during the 19th and 20th centuries.
journal_name
Arch Iran Medjournal_title
Archives of Iranian medicineauthors
Azizi MH,Bahadori Mdoi
011146/AIM.0014subject
Has Abstractpub_date
2011-11-01 00:00:00pages
425-30issue
6eissn
1029-2977issn
1735-3947pii
0014journal_volume
14pub_type
历史文章,杂志文章abstract：BACKGROUND:Regulation of reproduction is now considered to be carried out by the kisspeptin and its receptor, GPR54 or Kiss1r. Mutations of either Kiss1 or Kiss1r in humans and mice result in profound hypogonadotropic hypogonadism. The present study was aimed to determine whether the levels of kisspeptin are associated...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0151801/AIM.005
更新日期：2015-01-01 00:00:00
abstract：:Hereditary spherocytosis (HS), a familial defect involving red blood cell (RBC) membrane proteins, is associated with reduced deformability, increased fragility, and progressive destruction of spherical cells. The present study focuses on three subjects of a family showing a history of repeated episodes of lethargy an...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2020-03-01 00:00:00
abstract：BACKGROUND:Cardiovascular disease (CVD) is among the most common causes of mortality in all populations. Nonalcoholic steatohepatitis is a common finding in patients with CVD. Prevention of CVD in individual patients typically requires periodic clinical evaluation, as well as diagnosis and management of risk factors su...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：015188/AIM.009
更新日期：2015-08-01 00:00:00
abstract：BACKGROUND:Ankylosing spondylitis (AS; OMIM:106300) is a common complex inflammatory disease; in a previous study, we introduced a novel mutation in the RELN gene (OMIM: 600514) which was associated with AS. This study is designed to investigate the potential effect of RELN S2486G mutation on reelin secretion; addition...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：10.34172/aim.2020.87
更新日期：2020-10-01 00:00:00
abstract：:Placental mesenchymal dysplasia is a rare condition of the placenta and its true incidence and underlying cause has remained unknown till now due to its rarity. Its accurate diagnosis is essential, because placental mesenchymal dysplasia is usually compatible with a good fetal and maternal outcome. A precise ultrasono...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：013169/AIM.0013
更新日期：2013-09-01 00:00:00
abstract：OBJECTIVE:This study was conducted to evaluate the hematological effects of umbilical cord clamp timing and delivery type in term infants 48 hours after birth in Imam Hossein Hospital, Tehran, Iran. METHOD:From Oct 2007 - March 2008, 100 mother-infant eligible pairs were selected and divided by cord clamp timing (< or...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：010135/AIM.0010
更新日期：2010-09-01 00:00:00
abstract：BACKGROUND:Tendon entrapment of the first dorsal compartment of the wrist, the de Quervain disease, is a common cause of wrist and hand pain and disability. A group of 50 consecutive patients operated for the treatment of de Quervain disease from 2003 through 2006 were prospectively studied to determine the variation i...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：:Infection-associated hemophagocytic syndrome is a life-threatening condition characterized by prolonged fever, hepatosplenomegaly, and cytopenia-most commonly, thrombocytopenia and anemia. It is characterized by proliferation and activation of benign histiocytes, causing dysfunction of various organs. Herein, we repor...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2006-07-01 00:00:00
abstract：:The coronavirus infection is an evolving pandemic with high morbidity and mortality, especially in people with comorbidities. The case fatality rate (CFR) is 9.2% in the presence of diabetes, while it is 1.4% in those without any comorbidity. Diabetes is a prevalent disease globally; hence, healthcare professionals ar...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：10.34172/aim.2020.61
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:Coronavirus disease 2019 (COVID-19) has been widespread since late December 2019, with several symptoms related to the upper and lower respiratory system. However, its cardiac manifestations are less frequently studied. We aimed to analyze the available COVID-19 data on acute cardiac injury, using troponin a...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章,meta分析
doi：10.34172/aim.2020.107
更新日期：2020-11-01 00:00:00
abstract：BACKGROUND:Cystic craniopharyngiomas are the most frequent intracranial neoplasm of nonglial origin in children. Follow-up data were analyzed to assess the value of intracavitary irradiation with stereotactically applied 32P radioisotopes for the treatment of patients with craniopharyngioma cysts admitted to Shohada Ta...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：08111/AIM.009
更新日期：2008-01-01 00:00:00
abstract：BACKGROUND:It is well known that inhalation of chemical warfare, mostly sulfur mustard, causes injury of the respiratory system. Chronic obstructive pulmonary disease is a common disease among these patients. Health-related quality of life is a common feature of studies in chronic obstructive pulmonary disease. The obj...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2006-10-01 00:00:00
abstract：:Several studies have shown that patients with acromegaly are at increased risk of developing colorectal polyps and cancer. The prevalence of polyp in colon of patients with acromegaly was variously reported between 23% and 53%. This study was conducted to determine the prevalence of polyp and cancer of colon in patien...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：07102/AIM.0019
更新日期：2007-04-01 00:00:00
abstract：BACKGROUND:Hepatitis delta virus is a unique human pathogen responsible for some 20 million infections globally. This virus is dependent on hepatitis B virus for transmission and propagation. Currently, at least three genotypes of hepatitis delta virus with different geographic distribution and clinical manifestations ...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2009-05-01 00:00:00
abstract：:Fibrodysplasia ossificans progressiva is a rare and disabling syndrome, which is characterized by heterotopic ossifications and skeletal deformities. So far, around 200 patients with fibrodysplasia ossificans progressiva have been reported in the world literature. Herein, we analyze the clinical records of 7 known cas...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章,多中心研究
doi：07101/AIM.0018
更新日期：2007-01-01 00:00:00
abstract：BACKGROUND:we aimed to recap and highlight the major results of the Global Burden of Diseases, Injuries, and Risk Factors Study 2010 by mortality and morbidity to clarify the current health priorities and challenges in Iran. METHODS:We estimated Iran's mortality and burden of 289 diseases with 67 risk factors and 1160...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0141705/AIM.004
更新日期：2014-05-01 00:00:00
abstract：BACKGROUND:Functional foods are extensively studied for their cancer preventive effects. In the present study, we compared the anti-cancer activity of aqueous extracts of three species of mushrooms including: Pleurotus ostreatus (PAE), Auricularia polytricha (AAE) and Macrolepiota procera (MAE) on COLO-205 cells. METH...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0151805/AIM.006
更新日期：2015-05-01 00:00:00
abstract：:Heck's disease or focal epithelial hyperplasia is a benign contagious disease caused by human papillomavirus types 13 or 32. It occurs with low frequency in the Iranian population. This condition is characterized by the occurrence of multiple, small papules or nodules in the oral cavity, especially on the labial and b...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：BACKGROUND:Breast cancer is the leading cause of carcinoma death in women. Proper treatment depends on the consideration of molecular biology status of tumor cells, which may determine the patient's treatment and prognosis. To determine the prognostic models for this disease, we evaluated the role of cell proliferation...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章,多中心研究
doi：07101/AIM.008
更新日期：2007-01-01 00:00:00
abstract：BACKGROUND:Genetic and expression anomaly of HER-2 have been frequently observed in different cancers. However, an overall association of HER-2 polymorphism (Ile655Val) with available cancer studies has not yet been explored. In the present study, a probable correlation of HER-2 Ile655Val polymorphism with 6 major type...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章,meta分析,评审
doi：0161906/AIM.0011
更新日期：2016-06-01 00:00:00
abstract：BACKGROUND:The need for mental health care among children and adolescents in Iran, as in other low and middle income countries (LAMIC) remains mostly unmet. In this paper, we sought to provide an overview of the extent of unmet need and mental health services in Iran. We also aimed to propose approaches to address this...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0161911/AIM.0010
更新日期：2016-11-01 00:00:00
abstract：BACKGROUND:Thalassemia major and its treatment by stem cell transplantation can have deleterious effects on bone integrity. This study assesses the adverse effects of transplantation on growing bones of pediatric thalassemic patients. METHODS:Bone mineral density (BMD) of 20 patients from three thalassemia classes who...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：013162/AIM.008
更新日期：2013-02-01 00:00:00
abstract：BACKGROUND:Abnormal expression of microRNAs (miRNAs) plays an important role in development of several cancer types, including bladder cancer (BCa). However, the relationship between the ratio of miR-181/miR-100 and the prognosis of BCa has not been studied yet. The aim of this study was to evaluate the expression of m...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0161909/AIM.008
更新日期：2016-09-01 00:00:00
abstract：PURPOSE:To evaluate the outcome of laparoendoscopic single-site (LESS-A) through one transumbilical port vs. 3-port laparoscopic (3TA) appendectomy in children. METHODS:We reviewed the records of 309 children (65 LESS-A, 244 3TA) operated on between 2008 and 2012. One hundered forty-nine patients had acute catarrhalis...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0161901/AIM.0011
更新日期：2016-01-01 00:00:00
abstract：:Chronic myelogenous leukemia (CML) and tuberculosis (TB) are diseases with effective available therapy. Treating patients who are afflicted simultaneously with both of these conditions is challenging due to significant drug interactions and the requirement of strict adherence to the multi-agent treatment regimen. Here...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0151801/AIM.0015
更新日期：2015-01-01 00:00:00
abstract：:Nationwide implementation of Family Physician (FP) program started in 2005 and targeted almost 25,000,000 citizens residing in rural areas and cities with less than 20,000 populations in Iran. Despite its blatant initiation that resulted in some modest achievements, the future of FP looks unclear in Iran. Thus far, no...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0141711/AIM.0012
更新日期：2014-11-01 00:00:00
abstract：:As there is a significant number of Iranian immigrant and illegal refugees living in marginal areas of large cities that might induce immunization gap in these areas. The aim of this study was to provide reliable information on vaccination status of these people. A cross sectional study was conducted on children 24-4...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0141710/AIM.0011
更新日期：2014-10-01 00:00:00
abstract：BACKGROUND:The probiotic microorganisms are live normal flora that provide nutritional benefits. When probiotic administered in adequate amounts, they also confer a health benefit on the host. Different mechanisms of probiotic effects include the following: stimulating the immune system, modifying the composition of no...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：0151803/AIM.006
更新日期：2015-03-01 00:00:00
abstract：:The early efforts for promotion of public health measures and prevention of fatal epidemic diseases in Iran date back to the second half of the 19th century. Based on historical records, the informal protosanitary councils had existed since the early 1850s, but a new formal health institution called "Sanitary Council"...
journal_title：Archives of Iranian medicine
pub_type： 历史文章,杂志文章
doi：07101/AIM.0028
更新日期：2007-01-01 00:00:00
abstract：BACKGROUND:Preventing violence is important especially in the Middle East, where many countries are struggling with violence. Knowing the affecting factors could help public policy makers to decrease violence level. Thus, this study is aimed to analyze health and other socio-economic factors that could affect interpers...
journal_title：Archives of Iranian medicine
pub_type： 杂志文章
doi：
更新日期：2020-02-01 00:00:00
