Serum total adiponectin level and risk of cardiovascular disease in Han Chinese populations: a meta-analysis of 17 case-control studies.

abstract：PURPOSE:We aim to evaluate the association of PCOS with eating, sleeping and sexual function disorders. METHODS:A comprehensive search including MEDLINE, Embase, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and Scopus through 01 August 2018 was conducted for studies reportin...

journal_title：Clinical endocrinology

authors： Thannickal A,Brutocao C,Alsawas M,Morrow A,Zaiem F,Murad MH,Javed Chattha A

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Mutations in CYP21A2 lead to deficiency of 21-hydroxylase and can have either severe or moderate effects on phenotype, which can be prevented by early treatment. We studied long-term effects of this deficiency on phenotype in patients who had not been treated for prolonged periods and correlated these phenot...

journal_title：Clinical endocrinology

authors： Goossens K,Juniarto AZ,Timmerman MA,Faradz SM,Wolffenbuttel KP,Drop SL,de Jong FH

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVE:With increasing use of computed tomography and magnetic resonance imaging, pituitary adenomas are being discovered incidentally with increasing frequency. However, limited data are available concerning the clinical importance and natural history of such 'incicentalomas'. We have undertaken a prospective study...

journal_title：Clinical endocrinology

authors： Feldkamp J,Santen R,Harms E,Aulich A,Mödder U,Scherbaum WA

更新日期：1999-07-01 00:00:00

abstract：OBJECTIVE:Androgens have paradoxically different effects on hair follicles depending on body site, stimulating beard growth while inducing regression in some areas of the scalp. The mesenchyme derived dermal papilla at the base of the hair follicle regulates many aspects of the growth of follicular epithelium, and is p...

journal_title：Clinical endocrinology

authors： Thornton MJ,Laing I,Hamada K,Messenger AG,Randall VA

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVE:Complications of childhood cirrhosis include abnormal growth and malnutrition, associated with abnormalities in circulating IGFs and IGFBPs. Controlled studies suggest that intensive enteral feeding enhances nutritional status. The aim was to ascertain whether nasogastric feeding improves nutritional status i...

journal_title：Clinical endocrinology

authors： Holt RI,Miell JP,Jones JS,Mieli-Vergani G,Baker AJ

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:We recently identified a novel anorexigenic protein, nesfatin-1, which is processed from nesfatin/nucleobindin-2 (NUCB2). However, the clinical importance of this protein has not been determined. OBJECTIVE:To investigate its clinical significance in humans, we have established a new specific enzyme-linked i...

journal_title：Clinical endocrinology

authors： Tsuchiya T,Shimizu H,Yamada M,Osaki A,Oh-I S,Ariyama Y,Takahashi H,Okada S,Hashimoto K,Satoh T,Kojima M,Mori M

更新日期：2010-10-01 00:00:00

abstract：:A controlled therapeutic trial on seventy-four 70-year-old women was carried out with the purpose of finding the optimal treatment for post menopausal osteoporosis. The bone mineral content (BMC) was measured by I-photonabsorptiometry at two sites in the distal part of the forearms, where the trabecular/cortical ratio...

journal_title：Clinical endocrinology

authors： Jensen GF,Christiansen C,Transbøl I

更新日期：1982-05-01 00:00:00

abstract：:Trilostane is a competitive inhibitor of 3 beta-hydroxysteroid dehydrogenase activity in vitro and an orally active inhibitor of steroidogenesis in vivo. A cytochemical section bioassay for this drug (4 alpha, 5-epoxy-17 beta-hydroxy-3-oxo-5 alpha-androstane-2 alpha-carbonitrile) in human plasma has been developed. Th...

journal_title：Clinical endocrinology

authors： Earnshaw RJ,Mitchell R,Robertson WR

更新日期：1984-07-01 00:00:00

abstract：:Twenty-four hyperprolactinaemic women were treated for 6 months with the new, non-ergot, long-acting dopamine agonist, CV 205-502. The treatment resulted in normalization of PRL secretion in 17 of the 24 women at once-daily doses of 0.05 to 0.15 mg of the drug. Sixteen of these women as well as 4 of those who remained...

journal_title：Clinical endocrinology

authors： Rasmussen C,Bergh T,Wide L,Brownell J

更新日期：1988-09-01 00:00:00

abstract：:The glucocorticoid hormone cortisol is released in pulses resulting in a complex and dynamic ultradian rhythm of plasma cortisol that underlies the classical circadian rhythm. These oscillating levels are also seen at the level of tissues such as the brain and trigger pulses of gene activation and downstream signallin...

journal_title：Clinical endocrinology

authors： Russell GM,Durant C,Ataya A,Papastathi C,Bhake R,Woltersdorf W,Lightman S

更新日期：2014-08-01 00:00:00

abstract：:A 16-year-old female patient with an adrenal tumour was studied. Clinically she had progressive hirsutism, showed high urinary 17-oxosteroid excretion with normal plasma cortisol. Plasma C19-steroids, both unconjugated (including testosterone) and sulphate-conjugated, were greatly elevated. On surgical exploration an ...

journal_title：Clinical endocrinology

authors： Huhtaniemi I,Kahri AI,Pelkonen R,Salmenperä M,Sivula A,Vihko R

更新日期：1978-04-01 00:00:00

abstract：BACKGROUND:Increased frequencies of adrenal tumours and testicular adrenal rest tumours (TART) have been reported in patients with 21-hydroxylase deficiency (21OHD). OBJECTIVE:Patients, methods and design From a cross-sectional population-based study of 101 adult Norwegian patients with 21OHD, sixty-two participated i...

journal_title：Clinical endocrinology

authors： Nermoen I,Rørvik J,Holmedal SH,Hykkerud DL,Fougner KJ,Svartberg J,Husebye ES,Løvås K

更新日期：2011-12-01 00:00:00

abstract：:The excretion of FSH, LH, oestrogens and pregnanediol was monitored once weekly in urine samples collected from eight peri-menopausal women aged 44-55 years (median, 52 years). Observations were commenced between 5 and 15 weeks before the menopause and were continued for 22-30 weeks after final menstruation. Amenorrho...

journal_title：Clinical endocrinology

authors： Metcalf MG,Donald RA,Livesey JH

更新日期：1982-11-01 00:00:00

abstract：:The citric acid cycle, also known as the Krebs cycle, plays an integral role in cellular metabolism and aerobic respiration. Mutations in genes encoding the citric acid cycle enzymes succinate dehydrogenase, fumarate hydratase and malate dehydrogenase all predispose to hereditary tumour syndromes. The succinate dehydr...

journal_title：Clinical endocrinology

authors： MacFarlane J,Seong KC,Bisambar C,Madhu B,Allinson K,Marker A,Warren A,Park SM,Giger O,Challis BG,Maher ER,Casey RT

更新日期：2020-11-01 00:00:00

abstract：:We have recently reported an impaired growth hormone (GH) response to a single i.v. bolus dose of growth hormone releasing factor (1 microgram/kg body weight) in obese women. We have now investigated whether the i.v. administration of low dose GHRF(1-29)NH2 (0.33 microgram/kg/h) by 15 min pulsed injections for 3 h fol...

journal_title：Clinical endocrinology

authors： Kopelman PG,Noonan K

更新日期：1986-02-01 00:00:00

abstract：OBJECTIVE:The body adiposity index (BAI) has been recently proposed as an alternative index to body mass index (BMI) and waist circumference (WC) to evaluate adiposity in adults, with special focus on its ability to discriminate gender specificities on adiposity. Endothelial dysfunction, circulating endothelial cells (...

journal_title：Clinical endocrinology

authors： Dias IB,Panazzolo DG,Marques MF,Paredes BD,Souza MG,Manhanini DP,Morandi V,Farinatti PT,Bouskela E,Kraemer-Aguiar LG

更新日期：2013-11-01 00:00:00

abstract：:This study deals with serum prolactin concentrations during various conditions in the early puerperium in an attempt to investigate some characteristics of the mechanisms responsible for the regulation of the lactotropes. In nursing, in non-nursing, non-medicated and in non-nursing, bromocriptine-treated women prolact...

journal_title：Clinical endocrinology

authors： Vemer HM,Rolland R

更新日期：1981-08-01 00:00:00

abstract：OBJECTIVE:Stimulation with corticotropin-releasing hormone (CRH) is one of principal tools for the differential diagnosis of ACTH-dependent Cushing's syndrome. However, different dosages and species of CRH may be employed; further, ACTH levels can be measured by radioimmunoassay (RIA) or immunoradiometric assay (IRMA)....

journal_title：Clinical endocrinology

authors： Pecori Giraldi F,Invitti C,Cavagnini F,Study Group of the Italian Society of Endocrinology on the Pathophysiology of the Hypothalamic-pituitary-adrenal axis.

更新日期：2001-05-01 00:00:00

abstract：PURPOSE:Massive macronodular adrenocortical disease (MMAD) may be caused by aberrant microRNA expression. To determine the microRNA profile in MMAD and identify putative microRNA-gene target pairs involved in adrenal tumourigenesis. EXPERIMENTAL DESIGN:We performed microRNA microarray analysis in 10 patients with ACTH...

journal_title：Clinical endocrinology

authors： Bimpaki EI,Iliopoulos D,Moraitis A,Stratakis CA

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:We have investigated plasma potassium changes during insulin-induced hypoglycaemia (IIH) in adult patients with growth hormone deficiency (GHD) who have low total body potassium and may also have a vulnerable myocardium due to an increased prevalence of atherosclerosis. DESIGN:Hypoglycaemia was induced throu...

journal_title：Clinical endocrinology

authors： Davies JS,Hinds NP,Millward EM,McDowell I,Scanlon MF

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:To assess the prevalence and progression of subclinical hypothyroidism in women with type 2 diabetes. DESIGN AND PATIENTS:Cross-sectional and longitudinal observational assessment of thyroid function in 420 adult females with type 2 diabetes randomly selected from participants in the community-based Fremantl...

journal_title：Clinical endocrinology

authors： Chubb SA,Davis WA,Inman Z,Davis TM

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVE:Over 1% of the UK population is receiving thyroid hormone replacement with l-thyroxine (T4). However, many patients complain of persistent lethargy and related symptoms on T4 even with normal TSH levels. To date there has been no large study to determine whether this is related to thyroxine replacement or coi...

journal_title：Clinical endocrinology

authors： Saravanan P,Chau WF,Roberts N,Vedhara K,Greenwood R,Dayan CM

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:The standard ACTH test in clinical use employs a pharmacological dose of ACTH which assesses the maximum secretory capacity of the adrenal cortex. We have investigated the responses of plasma adrenocortical steroids including cortisol, aldosterone and dehydroepiandrosterone (DHEA) to physiological doses of AC...

journal_title：Clinical endocrinology

authors： Daidoh H,Morita H,Mune T,Murayama M,Hanafusa J,Ni H,Shibata H,Yasuda K

更新日期：1995-09-01 00:00:00

abstract：OBJECTIVE:Here we use a novel ELISA that is specific for full-length visfatin (PBEF/NAMPT), compare it with the existing C-terminal based assay and use it to investigate associations of visfatin with metabolic parameters. DESIGN, PATIENTS AND MEASUREMENTS:We established the specificity and effectiveness of the new ELI...

journal_title：Clinical endocrinology

authors： Retnakaran R,Youn BS,Liu Y,Hanley AJ,Lee NS,Park JW,Song ES,Vu V,Kim W,Tungtrongchitr R,Havel PJ,Swarbrick MM,Shaw C,Sweeney G

更新日期：2008-12-01 00:00:00

abstract：INTRODUCTION:Confirmation of monogenic diabetes caused by glucokinase mutations (GCK-MODY) allows pharmacogenetic intervention in the form of insulin discontinuation. This is especially important among paediatric and young adult populations where GCK-MODY is most prevalent. METHODS:The study evaluated the utility of l...

journal_title：Clinical endocrinology

authors： Fendler W,Borowiec M,Antosik K,Szadkowska A,Deja G,Jarosz-Chobot P,Mysliwiec M,Wyka K,Pietrzak I,Skupien J,Malecki MT,Mlynarski W

更新日期：2011-09-01 00:00:00

abstract：:Five patients with Bloom's syndrome aged from 2 8/12 to 27 years, all of whom had hypogonadism, were subjected to an i.v. LHRH test and two of them to an i.m. HCG test. There was increased responsiveness of plasma LH and FSH, indicating that the hypogonadism is primary in nature and of early development. The tubular e...

journal_title：Clinical endocrinology

authors： Kauli R,Prager-lewin R,Kaufman H,Laron Z

更新日期：1977-04-01 00:00:00

abstract：OBJECTIVE:We have evaluated the efficacy of percutaneous ethanol injection as an alternative to surgery and iodine-131 treatment in solitary autonomous thyroid adenoma. DESIGN:Percutaneous ethanol injection (0.5-2.8 ml ethanol/ml nodular tissue) was performed under sonographic guidance in 3-5 (1-2 weekly) sessions; a ...

journal_title：Clinical endocrinology

authors： Monzani F,Goletti O,Caraccio N,Del Guerra P,Ferdeghini M,Pucci E,Baschieri L

更新日期：1992-05-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the overall ultrasonographic features and clinical factors that contribute to inadequate sampling in ultrasound-guided fine-needle aspiration biopsy (US-FNAB) of thyroid nodules. MATERIALS AND METHODS:From April 2008 to December 2008, 4077 US-FNABs in 3767 consecutive pati...

journal_title：Clinical endocrinology

authors： Choi SH,Han KH,Yoon JH,Moon HJ,Son EJ,Youk JH,Kim EK,Kwak JY

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:SRY-negative 46,XX testicular and ovotesticular disorders/differences of sex development (T/OTDSD) represent a very rare and unique DSD condition where testicular tissue develops in the absence of a Y chromosome. To date, very few studies have described the phenotype, clinical and surgical management and long...

journal_title：Clinical endocrinology

authors： Lambert S,Peycelon M,Samara-Boustani D,Hyon C,Dumeige L,Peuchmaur M,Fiot E,Léger J,Simon D,Paye-Jaouen A,Bouligand J,Siffroi JP,Carel JC,McElreavey K,El Ghoneimi A,Brachet C,Bouvattier C,Martinerie L

更新日期：2020-12-09 00:00:00

abstract：OBJECTIVE:It has previously been shown that patients with postpartum pituitary necrosis (Sheehan's syndrome, SS) have paradoxically increased TSH levels and loss of the nocturnal TSH surge. This study sought to determine the circadian and pulsatile characteristics of TSH secretion underlying those abnormalities. DESIG...

journal_title：Clinical endocrinology

authors： MacCagnan P,Oliveira JH,Castro V,Abucham J

更新日期：1999-10-01 00:00:00