Abstract:
BACKGROUND AND OBJECTIVE:The aim of this study was to validate the ability of the Finnish Diabetes Risk Score (FINDRISC) to predict the risk of DM2 in a population of south-eastern Spain (Pizarra Study). SUBJECTS AND METHODS:The Pizarra Study is a population-based prospective study developed in the town of Pizarra (Málaga). The first phase of the study was conducted in 1997-1998, including 1051 individuals aged 18-65 years randomly selected from the municipal census of the town. In 2003-2004 the subjects participating in the first study were reassessed. 824 individuals completed the second phase of the study (78.4%). All participants without known diabetes underwent an oral glucose tolerance test both at baseline and follow-up. We evaluated the ability of the FINDRISC to detect undiagnosed DM2 (first phase: cross-sectional study) and in predicting the incidence of DM2 (second phase: cohort study). RESULTS:The test showed good results both to detect undiagnosed DM2 (ROC-AUC 0.74) and to predict incident DM2 (ROC-AUC 0.75). The best prediction of risk of incident DM2 was found in those subjects with fasting glucose >100mg/dl and a FINDRISC ≥9 (OR: 19.37; 95%IC: 8,86-42,34; P<.0001). CONCLUSIONS:The results of our study show that FINDRISC can be a useful tool to detect subjects at high risk of diabetes in this population.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
Soriguer F,Valdés S,Tapia MJ,Esteva I,Ruiz de Adana MS,Almaraz MC,Morcillo S,García Fuentes E,Rodríguez F,Rojo-Martinez Gdoi
10.1016/j.medcli.2011.05.025subject
Has Abstractpub_date
2012-04-14 00:00:00pages
371-6issue
9eissn
0025-7753issn
1578-8989pii
S0025-7753(11)00822-0journal_volume
138pub_type
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