Fatal bilateral pneumothoraces following administration of aerosolised pentamidine.

Abstract:

:Aerosolised pentamidine (AP) is used for prophylaxis against infection with Pneumocystis jiroveci (carinii), a significant cause of morbidity and mortality for people with human immunodeficiency virus (HIV). In this article we report a 55 year old man with HIV and a background history of asthma since childhood, who suffered respiratory arrest and died within an hour of commencing AP prophylaxis. Autopsy revealed bilateral pneumothoraces. Common side effects of AP therapy include bronchospasm and coughing. Pneumothorax has been reported in several cases. To our knowledge, this is the first reported fatality from bilateral pneumothoraces.

journal_name

J Forensic Leg Med

authors

Green A,Milne N,Ong BB

doi

10.1016/j.jflm.2011.06.012

subject

Has Abstract

pub_date

2011-10-01 00:00:00

pages

332-5

issue

7

eissn

1752-928X

issn

1878-7487

pii

S1752-928X(11)00130-2

journal_volume

18

pub_type

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