Abstract:
:Matriptase is a type II transmembrane serine protease expressed abundantly in the epithelial cells and keratinocyte. It plays a key role in the establishment and maintenance of epithelial integrity. Matriptase is considered to be at the most upstream in cellular protease cascade. Activation of its zymogen is the most critical step in regulation of downstream proteases activities and physiological functions. It has recently found that the exposure of matriptase-expressing epithelial cells and its homogenate to mildly acidic pH induces the rapid activation of matriptase zymogen. On the other hand, high ionic strength prevents this activation. The activation of the zymogen is thought to be triggered by the acidification and the lowering of ionic strength in cell-surface microenvironments.
journal_name
J Biochemjournal_title
Journal of biochemistryauthors
Kojima K,Inouye Kdoi
10.1093/jb/mvr075subject
Has Abstractpub_date
2011-08-01 00:00:00pages
123-5issue
2eissn
0021-924Xissn
1756-2651pii
mvr075journal_volume
150pub_type
杂志文章abstract::We describe cross-linking conditions for myosin subfragment-1 and actin with 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide, with which the compositions of cross-linked species can be altered. The specific Mg-ATPase activity of cross-linked subfragment-1 in these preparations was almost the same in spite of the diffe...
journal_title:Journal of biochemistry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.jbchem.a124254
更新日期:1993-12-01 00:00:00
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journal_title:Journal of biochemistry
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doi:10.1093/oxfordjournals.jbchem.a133119
更新日期:1980-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/oxfordjournals.jbchem.a123023
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pub_type: 杂志文章
doi:10.1093/jb/mvj088
更新日期:2006-04-01 00:00:00
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journal_title:Journal of biochemistry
pub_type: 杂志文章
doi:
更新日期:1990-12-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/oxfordjournals.jbchem.a122268
更新日期:1988-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:2014-01-01 00:00:00
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journal_title:Journal of biochemistry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.jbchem.a123329
更新日期:1991-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/oxfordjournals.jbchem.a123624
更新日期:1991-10-01 00:00:00
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pub_type: 杂志文章
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更新日期:2017-06-01 00:00:00
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journal_title:Journal of biochemistry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.jbchem.a122777
更新日期:1989-06-01 00:00:00
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journal_title:Journal of biochemistry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.jbchem.a002827
更新日期:2001-01-01 00:00:00
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journal_title:Journal of biochemistry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.jbchem.a122334
更新日期:1988-04-01 00:00:00
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journal_title:Journal of biochemistry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.jbchem.a122546
更新日期:1988-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/jb/mvv058
更新日期:2015-12-01 00:00:00
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journal_title:Journal of biochemistry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.jbchem.a132715
更新日期:1980-01-01 00:00:00
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journal_title:Journal of biochemistry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.jbchem.a134409
更新日期:1983-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/jb/mvn032
更新日期:2008-06-01 00:00:00
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pub_type: 杂志文章
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更新日期:1982-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:1998-04-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/oxfordjournals.jbchem.a123786
更新日期:1992-04-01 00:00:00
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pub_type: 杂志文章
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更新日期:1982-10-01 00:00:00
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journal_title:Journal of biochemistry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.jbchem.a132010
更新日期:1978-04-01 00:00:00
abstract::We studied the regulation of lipid body biogenesis in the oleaginous fungus Mortierella ramanniana var. angulispora by investigating culture conditions to modulate lipid body size, which we found was affected by the carbon-to-nitrogen ratio (C/N ratio) in the culture medium. Increasing the nitrogen source or decreasin...
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pub_type: 杂志文章
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更新日期:2004-02-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/oxfordjournals.jbchem.a131544
更新日期:1977-04-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/oxfordjournals.jbchem.a123308
更新日期:1990-12-01 00:00:00
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journal_title:Journal of biochemistry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.jbchem.a122715
更新日期:1989-04-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/oxfordjournals.jbchem.a135481
更新日期:1986-01-01 00:00:00
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journal_title:Journal of biochemistry
pub_type: 杂志文章
doi:10.1093/oxfordjournals.jbchem.a124538
更新日期:1994-08-01 00:00:00
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pub_type: 杂志文章
doi:10.1093/oxfordjournals.jbchem.a130800
更新日期:1975-05-01 00:00:00